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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

miR-1 and miR-206 regulate angiogenesis by modulating VegfA expression in zebrafish

Authors:
Stahlhut C, Suárez Y, Lu J, Mishima Y, Giraldez AJ
Citation:
Development. 2012;139:4356-4365. doi:10.1242/dev.083774
Epub:
Not Epub
Abstract:
Cellular communication across tissues is an essential process during embryonic development. Secreted factors with potent...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stahlhut C, Suárez Y, Lu J, Mishima Y, Giraldez AJ. miR-1 and miR-206 regulate angiogenesis by modulating VegfA expression in zebrafish. Development. 2012;139:4356-4365. doi:10.1242/dev.083774.

miRNA regulation of Sdf1 chemokine signaling provides genetic robustness to germ cell migration

Authors:
Staton AA, Knaut H, Giraldez AJ
Citation:
Nat Genet. 2011 Jan 23. [Epub ahead of print]
Epub:
Not Epub
Abstract:
microRNAs (miRNAs) function as genetic rheostats to control gene output. Based on their role as modulators, it has been...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Staton AA, Knaut H, Giraldez AJ. miRNA regulation of Sdf1 chemokine signaling provides genetic robustness to germ cell migration. Nat Genet. 2011 Jan 23. [Epub ahead of print].

Modulation of 5-HT3 receptor distribution by the light chain of MAP1B expressed in HEK 293 cells

Authors:
Sun H, Hu X, Emerit MB, Schoenebeck JC, Kimmel CE, Peoples RW, Miko A, Zhang L
Citation:
J Physiol. 2007 Dec 6; [Epub ahead of print]
Epub:
Not Epub
Abstract:
Regulation of ligand-gated ion channel (LGIC) function and trafficking by cytoskeleton proteins has been the topic of recent...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: HEK 293
Citation Extract:
Sun H, Hu X, Emerit MB, Schoenebeck JC, Kimmel CE, Peoples RW, Miko A, Zhang L. Modulation of 5-HT3 receptor distribution by the light chain of MAP1B expressed in HEK 293 cells. J Physiol. 2007 Dec 6; [Epub ahead of print].

Morpholino and Phosphorothioate Antisense Oligomers Compared in Cell-Free and In-Cell Systems

Authors:
Summerton J, Stein D, Huang SB, Matthews P, Weller D, Partridge M
Citation:
Antisense & Nucleic Acid Drug Development 1997 7: 63-70
Epub:
Not Epub
Abstract:
Morpholino and phosphorothioate (S-DNA) antisense oligos were compared in both cell-free and in-cell translation systems. In...
Delivery Method:
in vitro: TNT and scrape loading
Organism or Cell Type:
cell culture: HeLa cells
Citation Extract:
Summerton J, Stein D, Huang SB, Matthews P, Weller D, Partridge M. Morpholino and Phosphorothioate Antisense Oligomers Compared in Cell-Free and In-Cell Systems. Antisense & Nucleic Acid Drug Development 1997 7: 63-70.

Morpholino Antisense Oligomers: The Case for an RNase-H Independent Structural Type

Authors:
Summerton J
Citation:
Biochimica et Biophysica Acta 1999 1489: 141-158
Epub:
Not Epub
Abstract:
RNase H-competent phosphorothioates (S-DNAs) have dominated the antisense field in large part because they offer reasonable...
Citation Extract:
Summerton J. Morpholino Antisense Oligomers: The Case for an RNase-H Independent Structural Type. Biochimica et Biophysica Acta 1999 1489: 141-158.

Morpholino Antisense Oligos: Applications in Biopharmaceutical Research

Authors:
Summerton J
Citation:
Innovations in Pharmaceutical Technology. Sept 2005
Epub:
Not Epub
Abstract:
Oligos which bind to complementary RNA sequences are commonly called ‘antisense’ oligos because they are typically used to...
Citation Extract:
Summerton J. Morpholino Antisense Oligos: Applications in Biopharmaceutical Research. Innovations in Pharmaceutical Technology. Sept 2005.

Morpholino phosphorodiamidate oligonucleotides in zebrafish: A recipe for functional genomics?

Authors:
Sumanas S, Larson JD
Citation:
Briefings in Functional Genomics and Proteomics. 2002. 1(3):239-256
Epub:
Not Epub
Abstract:
Morpholino phosphorodiamidate anti-sense oligonucleotides (MPOs) have recently emerged as a tool for gene-specific knockdown....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sumanas S, Larson JD. Morpholino phosphorodiamidate oligonucleotides in zebrafish: A recipe for functional genomics?. Briefings in Functional Genomics and Proteomics. 2002. 1(3):239-256.

Morpholino, siRNA, and S-DNA Compared: Impact of Structure and Mechanism of Action on Off-Target Effects and Sequence Specificity

Authors:
Summerton J
Citation:
Med Chem. 2007;7(7):651-660
Epub:
Not Epub
Abstract:
Generally a gene knockdown agent should achieve high sequence specificity and should lack off-target effects (non-antisense...
Citation Extract:
Summerton J. Morpholino, siRNA, and S-DNA Compared: Impact of Structure and Mechanism of Action on Off-Target Effects and Sequence Specificity. Med Chem. 2007;7(7):651-660.

Morpholinos and PNAs compared

Authors:
Summerton J
Citation:
Letters in Peptide Science 2004 10: 215-236
Epub:
Not Epub
Abstract:
No abstract available.
Delivery Method:
various
Organism or Cell Type:
not applicable
Citation Extract:
Summerton J. Morpholinos and PNAs compared. Letters in Peptide Science 2004 10: 215-236.

Morpholinos and PNAs Compared In: Peptide Nucleic Acids, Morpholinos, and Related Antisense Biomolecules

Authors:
Summerton J
Citation:
Janson C. and During M., eds. Landes Biosciences 2004, Georgetown, TX.
Epub:
Not Epub
Citation Extract:
Summerton J. Morpholinos and PNAs Compared In: Peptide Nucleic Acids, Morpholinos, and Related Antisense Biomolecules. Janson C. and During M., eds. Landes Biosciences 2004, Georgetown, TX..

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