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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Zebrafish as a model system for drug target screening and validation
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Citation:
DDT: TARGETS. 2004 June;3(3):89-96 Epub:
Not Epub Abstract:
The zebrafish is becoming an increasingly popular model organism to study human diseases. Novel assays have been and continue... Organism or Cell Type:
Zebrafish (lit. review) Citation Extract: Sumanas S, Lin S. Zebrafish as a model system for drug target screening and validation. DDT: TARGETS. 2004 June;3(3):89-96. |
Zebrafish chaperone protein GP96 is required for otolith formation during ear development
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Citation:
Dev Biol. 2003 Sep 15;261(2):443-55. Epub:
Not Epub Abstract:
Chaperone proteins are considered to be fairly ubiquitous proteins that promote the correct folding and assembly of multiple... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Sumanas S, Larson JD, Miller Bever M.. Zebrafish chaperone protein GP96 is required for otolith formation during ear development. Dev Biol. 2003 Sep 15;261(2):443-55.. |
Zebrafish Chemical Screening Reveals the Impairment of Dopaminergic Neuronal Survival by Cardiac Glycosides
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Citation:
PLoS ONE. 2012;7(4):e35645. doi:10.1371/journal.pone.0035645 Epub:
Not Epub Abstract:
Parkinson's disease is a neurodegenerative disorder characterized by the prominent degeneration of dopaminergic (DA)... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Sun Y, Dong Z, Khodabakhsh H, Chatterjee S, Guo S. Zebrafish Chemical Screening Reveals the Impairment of Dopaminergic Neuronal Survival by Cardiac Glycosides. PLoS ONE. 2012;7(4):e35645. doi:10.1371/journal.pone.0035645. |
Zebrafish early cardiac connexin, Cx36.7/Ecx, regulates myofibril orientation and heart morphogenesis by establishing Nkx2.5 expression
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Citation:
Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4763-8. Epub 2008 Mar 12 Epub:
Not Epub Abstract:
Heart development is a precisely coordinated process of cellular proliferation, migration, differentiation, and integrated... Organism or Cell Type:
zebrafish Citation Extract: Sultana N, Nag K, Hoshijima K, Laird DW, Kawakami A, Hirose S. Zebrafish early cardiac connexin, Cx36.7/Ecx, regulates myofibril orientation and heart morphogenesis by establishing Nkx2.5 expression. Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4763-8. Epub 2008 Mar 12. |
Zebrafish frizzled-2 morphant displays defects in body axis elongation
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Citation:
Genesis. 2001 Jul;30(3):114-8. Epub:
Not Epub Abstract:
No abstract available. Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Sumanas S, Kim HJ, Hermanson S, Ekker SC. Zebrafish frizzled-2 morphant displays defects in body axis elongation. Genesis. 2001 Jul;30(3):114-8.. |
Zebrafish HSF4: a novel protein that shares features of both HSF1 and HSF4 of mammals
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Citation:
Cell Stress Chaperones. 2012 Apr 17. [Epub ahead of print] Epub:
Not Epub Abstract:
Heat-shock proteins (hsps) have important roles in the development of the eye lens. We previously demonstrated that knockdown... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Swan CL, Evans TG, Sylvain N, Krone PH. Zebrafish HSF4: a novel protein that shares features of both HSF1 and HSF4 of mammals. Cell Stress Chaperones. 2012 Apr 17. [Epub ahead of print]. |
Zebrafish models of p53 functions
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Cold Spring Harb Perspect Biol. 2010 Aug 1;2(8):a001123. Epub 2010 May 5 Epub:
Not Epub Abstract:
Zebrafish models have significantly contributed to our understanding of vertebrate development and, more recently, human... Organism or Cell Type:
zebrafish Citation Extract: Storer NY, Zon LI. Zebrafish models of p53 functions. Cold Spring Harb Perspect Biol. 2010 Aug 1;2(8):a001123. Epub 2010 May 5. |
Zili inhibits transforming growth factor-beta signaling by interacting with Smad4
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Citation:
J Biol Chem. 2010 Feb 5;285(6):4243-50. Epub 2009 Dec 9 Epub:
Not Epub Abstract:
Piwi proteins are required for germ cell proliferation, differentiation, and germ line stem cell maintenance. In normal tissues... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Sun H, Li D, Chen S, Liu Y, Liao X, Deng W, Li N, Zeng M, Tao D, Ma Y. Zili inhibits transforming growth factor-beta signaling by interacting with Smad4. J Biol Chem. 2010 Feb 5;285(6):4243-50. Epub 2009 Dec 9. |
A feedback loop mediated by degradation of an inhibitor is required to initiate neuronal differentiation
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Citation:
Genes Dev. 2010 Jan 15;24(2):206-18 Epub:
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Neuronal differentiation is regulated by proneural genes that promote neurogenesis and inhibitory mechanisms that maintain... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Sobieszczuk DF, Poliakov A, Xu Q, Wilkinson DG. A feedback loop mediated by degradation of an inhibitor is required to initiate neuronal differentiation. Genes Dev. 2010 Jan 15;24(2):206-18. |
A gene regulatory network subcircuit drives a dynamic pattern of gene expression
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Citation:
Science. 2007 Nov 2;318(5851):794-7 Epub:
Not Epub Abstract:
Early specification of endomesodermal territories in the sea urchin embryo depends on a moving torus of regulatory gene... Organism or Cell Type:
sea urchin Citation Extract: Smith J, Theodoris C, Davidson EH. A gene regulatory network subcircuit drives a dynamic pattern of gene expression. Science. 2007 Nov 2;318(5851):794-7. |