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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

A Mechanoresponsive Cadherin-Keratin Complex Directs Polarized Protrusive Behavior and Collective Cell Migration

Authors:
Weber GF, Bjerke MA, DeSimone DW
Citation:
Dev Cell. 2011;[Epub ahead of print] doi:10.1016/j.devcel.2011.10.013
Epub:
Not Epub
Abstract:
Collective cell migration requires maintenance of adhesive contacts between adjacent cells, coordination of polarized cell...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Weber GF, Bjerke MA, DeSimone DW. A Mechanoresponsive Cadherin-Keratin Complex Directs Polarized Protrusive Behavior and Collective Cell Migration. Dev Cell. 2011;[Epub ahead of print] doi:10.1016/j.devcel.2011.10.013.

A role for foxd3 and sox10 in the differentiation of gonadotropin-releasing hormone (GnRH) cells in the zebrafish Danio rerio

Authors:
Whitlock KE, Smith KM, Kim H, Harden MV
Citation:
Development. 2005 Dec;132(24):5491-502. Epub 2005 Nov 16
Epub:
Not Epub
Abstract:
Gonadotropin-releasing hormone (GnRH) is found in a wide range of vertebrate tissues, including the nervous system. In general...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Whitlock KE, Smith KM, Kim H, Harden MV. A role for foxd3 and sox10 in the differentiation of gonadotropin-releasing hormone (GnRH) cells in the zebrafish Danio rerio. Development. 2005 Dec;132(24):5491-502. Epub 2005 Nov 16.

Abnormal vasculature interferes with optic fissure closure in lmo2 mutant zebrafish embryos

Authors:
Weiss O, Kaufman R, Michaeli N, Inbal A
Citation:
Dev Biol. 2012 Jul 17. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Ocular coloboma is a potentially blinding congenital eye malformation caused by failure of optic fissure closure during early...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Weiss O, Kaufman R, Michaeli N, Inbal A. Abnormal vasculature interferes with optic fissure closure in lmo2 mutant zebrafish embryos. Dev Biol. 2012 Jul 17. [Epub ahead of print].

ADAM13 induces cranial neural crest by cleaving class B Ephrins and regulating Wnt signaling

Authors:
Wei S, Xu G, Bridges LC, Williams P, White JM, DeSimone DW
Citation:
Dev Cell. 2010 Aug 17;19(2):345-52
Epub:
Not Epub
Abstract:
The cranial neural crest (CNC) consists of multipotent embryonic cells that contribute to craniofacial structures and other...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Wei S, Xu G, Bridges LC, Williams P, White JM, DeSimone DW. ADAM13 induces cranial neural crest by cleaving class B Ephrins and regulating Wnt signaling. Dev Cell. 2010 Aug 17;19(2):345-52.

Advanced antisense therapies for postexposure protection against lethal filovirus infections

Authors:
Warren TK, Warfield KL, Wells J, Swenson DL, Donner KS, Van Tongeren SA, Garza NL, Dong L, Mourich DV, Crumley S, Nichols DK, Iversen PL, Bavari S
Citation:
Nat Med. 2010 Sep;16(9):991-4. doi: 10.1038/nm.2202. Epub 2010 Aug 22. PMID: 20729866
Epub:
Not Epub
Abstract:
Currently, no vaccines or therapeutics are licensed to counter Ebola or Marburg viruses, highly pathogenic filoviruses that are...
Link:
https://www.nature.com/articles/nm.2202
Delivery Method:
Injection
Organism or Cell Type:
monkey: rhesus, cynomolgus
Citation Extract:
Warren TK, Warfield KL, Wells J, Swenson DL, Donner KS, Van Tongeren SA, Garza NL, Dong L, Mourich DV, Crumley S, Nichols DK, Iversen PL, Bavari S. Advanced antisense therapies for postexposure protection against lethal filovirus infections. Nat Med. 2010 Sep;16(9):991-4. doi: 10.1038/nm.2202. Epub 2010 Aug 22. PMID: 20729866.

Advanced morpholino oligomers: a novel approach to antiviral therapy

Authors:
Warren TK, Shurtleff AC, Bavari S
Citation:
Antiviral Res. 2012 Apr;94(1):80-8. doi: 10.1016/j.antiviral.2012.02.004. Epub 2012 Feb 14. PMID: 22353544; PMCID: PMC7114334
Epub:
Not Epub
Abstract:
Phosphorodiamidate morpholino oligomers (PMOs) are synthetic antisense oligonucleotide analogs that are designed to interfere...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC7114334/
Citation Extract:
Warren TK, Shurtleff AC, Bavari S. Advanced morpholino oligomers: a novel approach to antiviral therapy. Antiviral Res. 2012 Apr;94(1):80-8. doi: 10.1016/j.antiviral.2012.02.004. Epub 2012 Feb 14. PMID: 22353544; PMCID: PMC7114334.

An octaguanidine-morpholino oligo conjugate improves muscle function of mdx mice

Authors:
Widrick JJ, Jiang S, Choi SJ, Knuth ST, Morcos PA
Citation:
Muscle & Nerve 2011 [Epub ahead of print]
Epub:
Not Epub
Abstract:
Introduction: Skeletal muscles of mdx mice lack functional levels of dystrophin due to a mutation in Dmd exon 23. Morpholino...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice, mdx
Citation Extract:
Widrick JJ, Jiang S, Choi SJ, Knuth ST, Morcos PA. An octaguanidine-morpholino oligo conjugate improves muscle function of mdx mice. Muscle & Nerve 2011 [Epub ahead of print].

Analysis of the zebrafish perplexed mutation reveals tissue specific roles for de novo pyrimidine synthesis during development

Authors:
Willer GB, Lee VM, Gregg RG, Link BA
Citation:
Genetics. 2005 Aug;170(4):1827-37. Epub 2005 Jun 3.
Epub:
Not Epub
Abstract:
The zebrafish perplexed mutation disrupts cell proliferation and differentiation during retinal development. In addition,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Willer GB, Lee VM, Gregg RG, Link BA. Analysis of the zebrafish perplexed mutation reveals tissue specific roles for de novo pyrimidine synthesis during development. Genetics. 2005 Aug;170(4):1827-37. Epub 2005 Jun 3..

Angiomotin-like2 Gene (amotl2) Is Required for Migration and Proliferation of Endothelial Cells during Angiogenesis

Authors:
Wang Y, Li Z, Xu P, Huang L, Tong J, Huang H, Meng A
Citation:
J Biol Chem. 2011 Nov 25;286(47):41095-104. Epub 2011 Sep 20
Epub:
Not Epub
Abstract:
Angiogenesis involves sprouting, migration, and proliferation of endothelial cells. The angiomotin-like2 gene (amotl2) has been...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang Y, Li Z, Xu P, Huang L, Tong J, Huang H, Meng A. Angiomotin-like2 Gene (amotl2) Is Required for Migration and Proliferation of Endothelial Cells during Angiogenesis. J Biol Chem. 2011 Nov 25;286(47):41095-104. Epub 2011 Sep 20.

Antisense approaches for elucidating ranavirus gene function in an infected fish cell line

Authors:
Whitley DS, Sample RC, Sinning AR, Henegar J, Chinchar VG
Citation:
Dev Comp Immunol. 2011 Sep;35(9):937-48. doi: 10.1016/j.dci.2010.12.002. Epub 2010 Dec 13.
Epub:
Not Epub
Abstract:
Viral virulence/immune evasion strategies and host anti-viral responses represent different sides of the continuing struggle...
Link:
https://www.sciencedirect.com/science/article/pii/S0145305X10002867
Organism or Cell Type:
cell culture: fish cells, frog virus 3
Citation Extract:
Whitley DS, Sample RC, Sinning AR, Henegar J, Chinchar VG. Antisense approaches for elucidating ranavirus gene function in an infected fish cell line. Dev Comp Immunol. 2011 Sep;35(9):937-48. doi: 10.1016/j.dci.2010.12.002. Epub 2010 Dec 13..

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