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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
The protein tyrosine phosphatase Pez regulates TGFbeta, epithelial mesenchymal transition, and organ development
Citation:
J Cell Biol. 2007 Sep 24;178(7):1223-35 Epub:
Not Epub Abstract:
Epithelial-mesenchymal transition (EMT), crucial during embryogenesis for new tissue and organ formation, is also considered to... Organism or Cell Type:
zebrafish Citation Extract: Wyatt L, Wadham C, Crocker LA, Lardelli M, Khew-Goodall Y. The protein tyrosine phosphatase Pez regulates TGFbeta, epithelial mesenchymal transition, and organ development. J Cell Biol. 2007 Sep 24;178(7):1223-35. |
The Snail repressor is required for PMC ingression in the sea urchin embryo. Development. 2007 Mar;134(6):1061-70
Citation:
Epub 2007 Feb 7 Epub:
Not Epub Abstract:
In metazoans, the epithelial-mesenchymal transition (EMT) is a crucial process for placing the mesoderm beneath the ectoderm.... Organism or Cell Type:
sea urchin Citation Extract: Wu SY, McClay DR. The Snail repressor is required for PMC ingression in the sea urchin embryo. Development. 2007 Mar;134(6):1061-70. Epub 2007 Feb 7. |
The tight junction scaffolding protein cingulin regulates neural crest cell migration
Citation:
Dev. Dyn. 2011 [Epub ahead of print] doi:10.1002/dvdy.22735 Epub:
Not Epub Abstract:
Neural crest cells give rise to a diverse range of structures during vertebrate development. These cells initially exist in the... Delivery Method:
Electroporation Organism or Cell Type:
chick embryo Citation Extract: Wu CY, Jhingory S, Taneyhill LA. The tight junction scaffolding protein cingulin regulates neural crest cell migration. Dev. Dyn. 2011 [Epub ahead of print] doi:10.1002/dvdy.22735. |
The you Gene Encodes an EGF-CUB Protein Essential for Hedgehog Signaling in Zebrafish
Citation:
PLoS Biol. 2005 Jan 11;3(3):e66 [Epub ahead of print] Epub:
Not Epub Abstract:
Hedgehog signaling is required for many aspects of development in vertebrates and invertebrates. Misregulation of the Hedgehog... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Woods IG, Talbot WS. The you Gene Encodes an EGF-CUB Protein Essential for Hedgehog Signaling in Zebrafish. PLoS Biol. 2005 Jan 11;3(3):e66 [Epub ahead of print]. |
Toward an oligonucleotide therapy for Duchenne muscular dystrophy: A complex development challenge
Citation:
Sci. Transl. Med. 2010;2:25ps15 Epub:
Not Epub Abstract:
Antisense oligonucleotide (AO)–mediated exon skipping is a promising new therapy for Duchenne muscular dystrophy (DMD),... Citation Extract: Wood MJA. Toward an oligonucleotide therapy for Duchenne muscular dystrophy: A complex development challenge. Sci. Transl. Med. 2010;2:25ps15. |
Twist is an essential regulator of the skeletogenic gene regulatory network in the sea urchin embryo
Citation:
Dev Biol. 2008 Apr 15. [Epub ahead of print] Epub:
Not Epub Abstract:
Recent work on the sea urchin endomesoderm gene regulatory network (GRN) offers many opportunities to study the specification... Organism or Cell Type:
sea urchin Citation Extract: Wu SY, Yang YP, McClay DR. Twist is an essential regulator of the skeletogenic gene regulatory network in the sea urchin embryo. Dev Biol. 2008 Apr 15. [Epub ahead of print]. |
WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development
Citation:
Cell. 2005 Jun 17;121(6):859-72 Epub:
Not Epub Abstract:
Histone H3 lysine 4 (K4) methylation has been linked to the transcriptional activation in a variety of eukaryotic species. Here... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Wysocka J, Swigut T, Milne TA, Dou Y, Zhang X, Burlingame AL, Roeder RG, Brivanlou AH, Allis CD. WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development. Cell. 2005 Jun 17;121(6):859-72. |
Wnt-frizzled signaling in neural crest formation.
Citation:
Trends Neurosci 2003 Jan;26(1):40-5 Epub:
Not Epub Abstract:
No abstract available. Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Wu J, Saint-Jeannet JP, Klein PS. Wnt-frizzled signaling in neural crest formation.. Trends Neurosci 2003 Jan;26(1):40-5. |
A DNA Repair Protein Involved in Heart and Blood Development
Citation:
Mol Cell Biol. 2006 Dec;26(23):9083-93. Epub 2006 Sep 11. Epub:
Not Epub Abstract:
AP endonuclease 1, a key enzyme in repairing abasic sites in DNA, is an embryonic lethal in mice. We are examining its role in... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang Y, Shupenko CC, Melo LF, Strauss PR. A DNA Repair Protein Involved in Heart and Blood Development. Mol Cell Biol. 2006 Dec;26(23):9083-93. Epub 2006 Sep 11.. |
A frameshift mutation in LRSAM1 is responsible for a dominant hereditary polyneuropathy
Citation:
Hum Mol Genet. 2012 Jan 15;21(2):358-70. doi: 10.1093/hmg/ddr471. Epub 2011 Oct 19. Epub:
Not Epub Abstract:
Despite the high number of genes identified in hereditary polyneuropathies/CMT, the genetic defect in many families is still... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Weterman MAJ, Sorrentino V, Kasher PR, Jakobs ME, van Engelen BGM, Fluiter K, de Wissel MB, Sizarov A, Nürnberg G, Nürnberg P, Zelcer N, Schelhaas HJ, Baas F. A frameshift mutation in LRSAM1 is responsible for a dominant hereditary polyneuropathy. Hum Mol Genet. 2012 Jan 15;21(2):358-70. doi: 10.1093/hmg/ddr471. Epub 2011 Oct 19.. |