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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

The protein tyrosine phosphatase Pez regulates TGFbeta, epithelial mesenchymal transition, and organ development

Authors:
Wyatt L, Wadham C, Crocker LA, Lardelli M, Khew-Goodall Y
Citation:
J Cell Biol. 2007 Sep 24;178(7):1223-35
Epub:
Not Epub
Abstract:
Epithelial-mesenchymal transition (EMT), crucial during embryogenesis for new tissue and organ formation, is also considered to...
Organism or Cell Type:
zebrafish
Citation Extract:
Wyatt L, Wadham C, Crocker LA, Lardelli M, Khew-Goodall Y. The protein tyrosine phosphatase Pez regulates TGFbeta, epithelial mesenchymal transition, and organ development. J Cell Biol. 2007 Sep 24;178(7):1223-35.

The Snail repressor is required for PMC ingression in the sea urchin embryo. Development. 2007 Mar;134(6):1061-70

Authors:
Wu SY, McClay DR
Citation:
Epub 2007 Feb 7
Epub:
Not Epub
Abstract:
In metazoans, the epithelial-mesenchymal transition (EMT) is a crucial process for placing the mesoderm beneath the ectoderm....
Organism or Cell Type:
sea urchin
Citation Extract:
Wu SY, McClay DR. The Snail repressor is required for PMC ingression in the sea urchin embryo. Development. 2007 Mar;134(6):1061-70. Epub 2007 Feb 7.

The tight junction scaffolding protein cingulin regulates neural crest cell migration

Authors:
Wu CY, Jhingory S, Taneyhill LA
Citation:
Dev. Dyn. 2011 [Epub ahead of print] doi:10.1002/dvdy.22735
Epub:
Not Epub
Abstract:
Neural crest cells give rise to a diverse range of structures during vertebrate development. These cells initially exist in the...
Delivery Method:
Electroporation
Organism or Cell Type:
chick embryo
Citation Extract:
Wu CY, Jhingory S, Taneyhill LA. The tight junction scaffolding protein cingulin regulates neural crest cell migration. Dev. Dyn. 2011 [Epub ahead of print] doi:10.1002/dvdy.22735.

The you Gene Encodes an EGF-CUB Protein Essential for Hedgehog Signaling in Zebrafish

Authors:
Woods IG, Talbot WS
Citation:
PLoS Biol. 2005 Jan 11;3(3):e66 [Epub ahead of print]
Epub:
Not Epub
Abstract:
Hedgehog signaling is required for many aspects of development in vertebrates and invertebrates. Misregulation of the Hedgehog...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Woods IG, Talbot WS. The you Gene Encodes an EGF-CUB Protein Essential for Hedgehog Signaling in Zebrafish. PLoS Biol. 2005 Jan 11;3(3):e66 [Epub ahead of print].

Toward an oligonucleotide therapy for Duchenne muscular dystrophy: A complex development challenge

Authors:
Wood MJA
Citation:
Sci. Transl. Med. 2010;2:25ps15
Epub:
Not Epub
Abstract:
Antisense oligonucleotide (AO)–mediated exon skipping is a promising new therapy for Duchenne muscular dystrophy (DMD),...
Citation Extract:
Wood MJA. Toward an oligonucleotide therapy for Duchenne muscular dystrophy: A complex development challenge. Sci. Transl. Med. 2010;2:25ps15.

Twist is an essential regulator of the skeletogenic gene regulatory network in the sea urchin embryo

Authors:
Wu SY, Yang YP, McClay DR
Citation:
Dev Biol. 2008 Apr 15. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Recent work on the sea urchin endomesoderm gene regulatory network (GRN) offers many opportunities to study the specification...
Organism or Cell Type:
sea urchin
Citation Extract:
Wu SY, Yang YP, McClay DR. Twist is an essential regulator of the skeletogenic gene regulatory network in the sea urchin embryo. Dev Biol. 2008 Apr 15. [Epub ahead of print].

WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development

Authors:
Wysocka J, Swigut T, Milne TA, Dou Y, Zhang X, Burlingame AL, Roeder RG, Brivanlou AH, Allis CD
Citation:
Cell. 2005 Jun 17;121(6):859-72
Epub:
Not Epub
Abstract:
Histone H3 lysine 4 (K4) methylation has been linked to the transcriptional activation in a variety of eukaryotic species. Here...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Wysocka J, Swigut T, Milne TA, Dou Y, Zhang X, Burlingame AL, Roeder RG, Brivanlou AH, Allis CD. WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development. Cell. 2005 Jun 17;121(6):859-72.

Wnt-frizzled signaling in neural crest formation.

Authors:
Wu J, Saint-Jeannet JP, Klein PS
Citation:
Trends Neurosci 2003 Jan;26(1):40-5
Epub:
Not Epub
Abstract:
No abstract available.
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Wu J, Saint-Jeannet JP, Klein PS. Wnt-frizzled signaling in neural crest formation.. Trends Neurosci 2003 Jan;26(1):40-5.

A DNA Repair Protein Involved in Heart and Blood Development

Authors:
Wang Y, Shupenko CC, Melo LF, Strauss PR
Citation:
Mol Cell Biol. 2006 Dec;26(23):9083-93. Epub 2006 Sep 11.
Epub:
Not Epub
Abstract:
AP endonuclease 1, a key enzyme in repairing abasic sites in DNA, is an embryonic lethal in mice. We are examining its role in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang Y, Shupenko CC, Melo LF, Strauss PR. A DNA Repair Protein Involved in Heart and Blood Development. Mol Cell Biol. 2006 Dec;26(23):9083-93. Epub 2006 Sep 11..

A frameshift mutation in LRSAM1 is responsible for a dominant hereditary polyneuropathy

Authors:
Weterman MAJ, Sorrentino V, Kasher PR, Jakobs ME, van Engelen BGM, Fluiter K, de Wissel MB, Sizarov A, Nürnberg G, Nürnberg P, Zelcer N, Schelhaas HJ, Baas F
Citation:
Hum Mol Genet. 2012 Jan 15;21(2):358-70. doi: 10.1093/hmg/ddr471. Epub 2011 Oct 19.
Epub:
Not Epub
Abstract:
Despite the high number of genes identified in hereditary polyneuropathies/CMT, the genetic defect in many families is still...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Weterman MAJ, Sorrentino V, Kasher PR, Jakobs ME, van Engelen BGM, Fluiter K, de Wissel MB, Sizarov A, Nürnberg G, Nürnberg P, Zelcer N, Schelhaas HJ, Baas F. A frameshift mutation in LRSAM1 is responsible for a dominant hereditary polyneuropathy. Hum Mol Genet. 2012 Jan 15;21(2):358-70. doi: 10.1093/hmg/ddr471. Epub 2011 Oct 19..

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