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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Rab13-dependent trafficking of RhoA is required for directional migration and angiogenesis

Authors:
Wu C, Agrawal S, Vasanji A, Drazba J, Sarkaria S, Xie J, Welch CM, Liu M, Anand-Apte B, Horowitz A
Citation:
J Biol Chem. 2011 Jul 1;286(26):23511-20. Epub 2011 May 4.
Epub:
Not Epub
Abstract:
Angiogenesis requires concomitant remodeling of cell junctions and migration, as exemplified by recent observations of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu C, Agrawal S, Vasanji A, Drazba J, Sarkaria S, Xie J, Welch CM, Liu M, Anand-Apte B, Horowitz A. Rab13-dependent trafficking of RhoA is required for directional migration and angiogenesis. J Biol Chem. 2011 Jul 1;286(26):23511-20. Epub 2011 May 4..

Retinotopic mapping requires focal adhesion kinase-mediated regulation of growth cone adhesion

Authors:
Woo S, Rowan DJ, Gomez TM
Citation:
J Neurosci. 2009 Nov 4;29(44):13981-91
Epub:
Not Epub
Abstract:
Adhesion controls growth cone motility, yet the effects of axon guidance cues on adhesion site dynamics are poorly understood....
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Woo S, Rowan DJ, Gomez TM. Retinotopic mapping requires focal adhesion kinase-mediated regulation of growth cone adhesion. J Neurosci. 2009 Nov 4;29(44):13981-91.

RNA-targeted splice-correction therapy for neuromuscular disease

Authors:
Wood MJ, Gait MJ, Yin H
Citation:
Brain. 2010 Feb 11. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Splice-modulation therapy, whereby molecular manipulation of premessenger RNA splicing is engineered to yield genetic...
Citation Extract:
Wood MJ, Gait MJ, Yin H. RNA-targeted splice-correction therapy for neuromuscular disease. Brain. 2010 Feb 11. [Epub ahead of print].

Role of Two Genes Encoding PACAP in Early Brain Development in Zebrafish

Authors:
Wu S, Adams BA, Fradinger EA, Sherwood NM
Citation:
Ann N Y Acad Sci. 2006 Jul;1070:602-21
Epub:
Not Epub
Abstract:
To study the role of pituitary adenylate cyclase-activating polypeptide (PACAP) in early brain development, we examined PACAP...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu S, Adams BA, Fradinger EA, Sherwood NM. Role of Two Genes Encoding PACAP in Early Brain Development in Zebrafish. Ann N Y Acad Sci. 2006 Jul;1070:602-21.

SNW1 Is a Critical Regulator of Spatial BMP Activity, Neural Plate Border Formation, and Neural Crest Specification in Vertebrate Embryos

Authors:
Wu MY, Ramel M-C, Howell M, Hill CS
Citation:
PLoS Biol. 2011;9(2):e1000593. doi:10.1371/journal.pbio.1000593
Epub:
Not Epub
Abstract:
Bone morphogenetic protein (BMP) gradients provide positional information to direct cell fate specification, such as patterning...
Delivery Method:
Microinjection
Organism or Cell Type:
Zebrafish and Xenopus laevis
Citation Extract:
Wu MY, Ramel M-C, Howell M, Hill CS. SNW1 Is a Critical Regulator of Spatial BMP Activity, Neural Plate Border Formation, and Neural Crest Specification in Vertebrate Embryos. PLoS Biol. 2011;9(2):e1000593. doi:10.1371/journal.pbio.1000593.

Spindle Position in Symmetric Cell Divisions during Epiboly Is Controlled by Opposing and Dynamic Apicobasal Forces

Authors:
Woolner S, Papalopulu N
Citation:
Dev Cell. 2012 Apr 17;22(4):775-87. Epub 2012 Mar 8
Epub:
Not Epub
Abstract:
Orientation of cell division is a vital aspect of tissue morphogenesis and growth. Asymmetric divisions generate cell fate...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Woolner S, Papalopulu N. Spindle Position in Symmetric Cell Divisions during Epiboly Is Controlled by Opposing and Dynamic Apicobasal Forces. Dev Cell. 2012 Apr 17;22(4):775-87. Epub 2012 Mar 8.

Study on effective mechanism of mycophenolic acid on antiangiogeneses in flk-GFP zebrafish

Authors:
Wu X, Zhong H, Yuan J, Li J, Luo X, Lin S
Citation:
Chin J Clin Pharmacol. 2008;24(4):311-4
Epub:
Not Epub
Abstract:
Objective To identify small molecules with potential of anti-angiogenesis (mycophenolic acid, MPA) from approved drugs and do...
Organism or Cell Type:
zebrafish
Citation Extract:
Wu X, Zhong H, Yuan J, Li J, Luo X, Lin S. Study on effective mechanism of mycophenolic acid on antiangiogeneses in flk-GFP zebrafish. Chin J Clin Pharmacol. 2008;24(4):311-4.

Targeted knockdown of insulin-like growth factor binding protein-2 (IGFBP-2) disrupts cardiovascular development in zebrafish embryos

Authors:
Wood AW, Schlueter PJ, Duan C
Citation:
Mol Endocrinol. 2005 Apr;19(4):1024-34. Epub 2004 Dec 23.
Epub:
Not Epub
Abstract:
Insulin-like growth factor binding protein-2 (IGFBP-2) is an evolutionarily conserved protein that binds insulin-like growth...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wood AW, Schlueter PJ, Duan C. Targeted knockdown of insulin-like growth factor binding protein-2 (IGFBP-2) disrupts cardiovascular development in zebrafish embryos. Mol Endocrinol. 2005 Apr;19(4):1024-34. Epub 2004 Dec 23..

Targeted Skipping of Human Dystrophin Exons in Transgenic Mouse Model Systemically for Antisense Drug Development

Authors:
Wu B, Benrashid E, Lu P, Cloer C, Zillmer A, Shaban M, Lu QL
Citation:
PLoS ONE. 2011;6(5):e19906. doi:10.1371/journal.pone.0019906
Epub:
Not Epub
Abstract:
Antisense therapy has recently been demonstrated with great potential for targeted exon skipping and restoration of dystrophin...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mouse hDMD, cell cultures
Citation Extract:
Wu B, Benrashid E, Lu P, Cloer C, Zillmer A, Shaban M, Lu QL. Targeted Skipping of Human Dystrophin Exons in Transgenic Mouse Model Systemically for Antisense Drug Development. PLoS ONE. 2011;6(5):e19906. doi:10.1371/journal.pone.0019906.

The microtubule-severing protein Spastin is essential for axon outgrowth in the zebrafish embryo

Authors:
Wood JD, Landers JA, Bingley M, McDermott CJ, Thomas-McArthur V, Gleadall LJ, Shaw PJ, Cunliffe VT
Citation:
Hum Mol Genet. 2006 Sep 15;15(18):2763-71. Epub 2006 Aug 7.
Epub:
Not Epub
Abstract:
Hereditary spastic paraplegia (HSP) is a collection of neurological disorders characterised by developmental failure or...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wood JD, Landers JA, Bingley M, McDermott CJ, Thomas-McArthur V, Gleadall LJ, Shaw PJ, Cunliffe VT. The microtubule-severing protein Spastin is essential for axon outgrowth in the zebrafish embryo. Hum Mol Genet. 2006 Sep 15;15(18):2763-71. Epub 2006 Aug 7..

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