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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

In-vivo analysis of formation and endocytosis of the Wnt/β-Catenin signaling complex in zebrafish embryos

Authors:
Hagemann AI, Kurz J, Kauffeld S, Chen Q, Reeves PM, Weber S, Schindler S, Davidson G, Kirchhausen T, Scholpp S
Citation:
J Cell Sci. 2014 Jul 29. pii: jcs.148767. [Epub ahead of print]
Epub:
Yes
Abstract:
After activation by Wnt/β-Catenin ligands, a multi-protein complex assembles at the clustering membrane-bound receptors and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hagemann AI, Kurz J, Kauffeld S, Chen Q, Reeves PM, Weber S, Schindler S, Davidson G, Kirchhausen T, Scholpp S. In-vivo analysis of formation and endocytosis of the Wnt/β-Catenin signaling complex in zebrafish embryos. J Cell Sci. 2014 Jul 29. pii: jcs.148767. [Epub ahead of print].

The RNA-binding protein rbm24 is transiently expressed in myoblasts and is required for myogenic differentiation during vertebrate development

Authors:
Grifone R, Xie X, Bourgeois A, Saquet A, Duprez D, Shi DL
Citation:
Mech Dev. 2014 Sep 10. pii: S0925-4773(14)00039-2. doi: 10.1016/j.mod.2014.08.003. [Epub ahead of print]
Epub:
Yes
Abstract:
RNA-binding proteins (RBP) contribute to gene regulation through post-transcriptional events. Despite the important roles...
Organism or Cell Type:
chick
Citation Extract:
Grifone R, Xie X, Bourgeois A, Saquet A, Duprez D, Shi DL. The RNA-binding protein rbm24 is transiently expressed in myoblasts and is required for myogenic differentiation during vertebrate development. Mech Dev. 2014 Sep 10. pii: S0925-4773(14)00039-2. doi: 10.1016/j.mod.2014.08.003. [Epub ahead of print].

The role of a lens survival pathway including sox2 and αA-crystallin in the evolution of cavefish eye degeneration

Authors:
Ma L, Parkhurst A, Jeffery WR
Citation:
Evodevo. 2014 Aug 28;5:28. doi: 10.1186/2041-9139-5-28. eCollection 2014
Epub:
Not Epub
Abstract:
Background: The teleost Astyanax mexicanus is a single species consisting of eyed surface-dwelling (surface fish) and blind...
Delivery Method:
microinjection
Organism or Cell Type:
Astyanax mexicanus
Citation Extract:
Ma L, Parkhurst A, Jeffery WR. The role of a lens survival pathway including sox2 and αA-crystallin in the evolution of cavefish eye degeneration. Evodevo. 2014 Aug 28;5:28. doi: 10.1186/2041-9139-5-28. eCollection 2014.

Promoter analysis of ventricular myosin heavy chain (vmhc) in zebrafish embryos

Authors:
Jin D, Ni TT, Hou J, Rellinger E, Zhong TP
Citation:
Dev Dyn. 2009 Jul;238(7):1760-7. doi: 10.1002/dvdy.22000
Epub:
Not Epub
Abstract:
In zebrafish, ventricular myosin heavy chain (vmhc) gene is initially expressed at the anterior lateral mesoderm and thereafter...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jin D, Ni TT, Hou J, Rellinger E, Zhong TP. Promoter analysis of ventricular myosin heavy chain (vmhc) in zebrafish embryos. Dev Dyn. 2009 Jul;238(7):1760-7. doi: 10.1002/dvdy.22000.

Cdon acts as a Hedgehog decoy receptor during proximal-distal patterning of the optic vesicle

Authors:
Cardozo MJ, Sánchez-Arrones L, Sandonis A, Sánchez-Camacho C, Gestri G, Wilson SW, Guerrero I, Bovolenta P.
Citation:
Nat Commun. 2014 Jul 8;5:4272. doi: 10.1038/ncomms5272
Epub:
Not Epub
Abstract:
Patterning of the vertebrate optic vesicle into proximal/optic stalk and distal/neural retina involves midline-derived...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cardozo MJ, Sánchez-Arrones L, Sandonis A, Sánchez-Camacho C, Gestri G, Wilson SW, Guerrero I, Bovolenta P.. Cdon acts as a Hedgehog decoy receptor during proximal-distal patterning of the optic vesicle. Nat Commun. 2014 Jul 8;5:4272. doi: 10.1038/ncomms5272.

In vivo mutation of pre-mRNA processing factor 8 (Prpf8) affects transcript splicing, cell survival and myeloid differentiation

Authors:
Keightley MC, Crowhurst MO, Layton JE, Beilharz T, Markmiller S, Varma S, Hogan BM, de Jong-Curtain TA, Heath JK, Lieschke GJ
Citation:
FEBS Lett. 2013 Jul 11;587(14):2150-7. doi: 10.1016/j.febslet.2013.05.030. Epub 2013 May 25
Epub:
Not Epub
Abstract:
Mutated spliceosome components are recurrently being associated with perturbed tissue development and disease pathogenesis....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Keightley MC, Crowhurst MO, Layton JE, Beilharz T, Markmiller S, Varma S, Hogan BM, de Jong-Curtain TA, Heath JK, Lieschke GJ. In vivo mutation of pre-mRNA processing factor 8 (Prpf8) affects transcript splicing, cell survival and myeloid differentiation. FEBS Lett. 2013 Jul 11;587(14):2150-7. doi: 10.1016/j.febslet.2013.05.030. Epub 2013 May 25.

Elephant shark genome provides unique insights into gnathostome evolution

Authors:
Venkatesh B, Lee AP, Ravi V, Maurya AK, Lian MM, Swann JB, Ohta Y, Flajnik MF, Sutoh Y, Kasahara M, Hoon S, Gangu V, Roy SW, Irimia M, Korzh V, Kondrychyn I, Lim ZW, Tay BH, Tohari S, Kong KW, Ho S, Lorente-Galdos B, Quilez J, Marques-Bonet T, Raney BJ, Ingham PW, Tay A, Hillier LW, Minx P, Boehm T, Wilson RK, Brenner S, Warren WC
Citation:
Nature. 2014 Jan 9;505(7482):174-9. doi: 10.1038/nature12826
Epub:
Not Epub
Abstract:
The emergence of jawed vertebrates (gnathostomes) from jawless vertebrates was accompanied by major morphological and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Venkatesh B, Lee AP, Ravi V, Maurya AK, Lian MM, Swann JB, Ohta Y, Flajnik MF, Sutoh Y, Kasahara M, Hoon S, Gangu V, Roy SW, Irimia M, Korzh V, Kondrychyn I, Lim ZW, Tay BH, Tohari S, Kong KW, Ho S, Lorente-Galdos B, Quilez J, Marques-Bonet T, Raney BJ, Ingham PW, Tay A, Hillier LW, Minx P, Boehm T, Wilson RK, Brenner S, Warren WC. Elephant shark genome provides unique insights into gnathostome evolution. Nature. 2014 Jan 9;505(7482):174-9. doi: 10.1038/nature12826.

Acetylcholine serves as a derepressor in Loperamide-induced Opioid-Induced Bowel Dysfunction (OIBD) in zebrafish

Authors:
Shi Y, Zhang Y, Zhao F, Ruan H, Huang H, Luo L, Li L
Citation:
Sci Rep. 2014 Jul 7;4:5602. doi: 10.1038/srep05602
Epub:
Not Epub
Abstract:
The mechanisms underlying gut development, especially peristalsis, are widely studied topics. However, the causes of gut...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shi Y, Zhang Y, Zhao F, Ruan H, Huang H, Luo L, Li L. Acetylcholine serves as a derepressor in Loperamide-induced Opioid-Induced Bowel Dysfunction (OIBD) in zebrafish. Sci Rep. 2014 Jul 7;4:5602. doi: 10.1038/srep05602.

Mycobacteria counteract a TLR-mediated nitrosative defense mechanism in a zebrafish infection model

Authors:
Elks PM, van der Vaart M, van Hensbergen V, Schutz E, Redd MJ, Murayama E, Spaink HP, Meijer AH
Citation:
PLoS One. 2014 Jun 26;9(6):e100928. doi: 10.1371/journal.pone.0100928. eCollection 2014
Epub:
Not Epub
Abstract:
Pulmonary tuberculosis (TB), caused by the intracellular bacterial pathogen Mycobacterium tuberculosis (Mtb), is a major world...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Elks PM, van der Vaart M, van Hensbergen V, Schutz E, Redd MJ, Murayama E, Spaink HP, Meijer AH. Mycobacteria counteract a TLR-mediated nitrosative defense mechanism in a zebrafish infection model. PLoS One. 2014 Jun 26;9(6):e100928. doi: 10.1371/journal.pone.0100928. eCollection 2014.

Inhibiting glucose-regulated protein 78 modulates lipid metabolism through controlling stearoyl-CoA desaturase 1

Authors:
Cook K, Clarke P, Warri A, Clarke R
Citation:
Cancer Metab. 2014;2(Suppl 1):P16. doi:10.1186/2049-3002-2-S1-P16
Epub:
Not Epub
Abstract:
Of the 230,000 new cases of invasive breast cancer diagnosed annually, 70% express the estrogen receptor-α and may be treated...
Organism or Cell Type:
cell culture, tumors: LCC1 cells
Citation Extract:
Cook K, Clarke P, Warri A, Clarke R. Inhibiting glucose-regulated protein 78 modulates lipid metabolism through controlling stearoyl-CoA desaturase 1. Cancer Metab. 2014;2(Suppl 1):P16. doi:10.1186/2049-3002-2-S1-P16.

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