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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Ethanol-induced upregulation of 10-formyltetrahydrofolate dehydrogenase helps relieve ethanol-induced oxidative stress

Authors:
Hsiao TH, Lin CJ, Chung YS, Lee GH, Kao TT, Chang WN, Chen BH, Hung JJ, Fu TF
Citation:
Mol Cell Biol. 2014 Feb;34(3):498-509. doi: 10.1128/MCB.01427-13. Epub 2013 Nov 25
Epub:
Not Epub
Abstract:
Alcoholism induces folate deficiency and increases the risk for embryonic anomalies. However, the interplay between ethanol...
Link:
http://mcb.asm.org/content/34/3/498.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hsiao TH, Lin CJ, Chung YS, Lee GH, Kao TT, Chang WN, Chen BH, Hung JJ, Fu TF. Ethanol-induced upregulation of 10-formyltetrahydrofolate dehydrogenase helps relieve ethanol-induced oxidative stress. Mol Cell Biol. 2014 Feb;34(3):498-509. doi: 10.1128/MCB.01427-13. Epub 2013 Nov 25.

Yeast Augmented Network Analysis (YANA): a new systems approach to identify therapeutic targets for human genetic diseases

Authors:
Wiley DJ, Juan I, Le H, Cai X, Baumbach L, Beattie C, D'Urso G
Citation:
F1000Res. 2014 Jun 2;3:121. doi: 10.12688/f1000research.4188.1. eCollection 2014
Epub:
Not Epub
Abstract:
Genetic interaction networks that underlie most human diseases are highly complex and poorly defined. Better-defined networks...
Link:
http://f1000research.com/articles/3-121/v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wiley DJ, Juan I, Le H, Cai X, Baumbach L, Beattie C, D'Urso G. Yeast Augmented Network Analysis (YANA): a new systems approach to identify therapeutic targets for human genetic diseases. F1000Res. 2014 Jun 2;3:121. doi: 10.12688/f1000research.4188.1. eCollection 2014.

Cell-fibronectin interactions propel vertebrate trunk elongation via tissue mechanics

Authors:
Dray N, Lawton A, Nandi A, Jülich D, Emonet T, Holley SA
Citation:
Curr Biol. 2013 Jul 22;23(14):1335-41. doi: 10.1016/j.cub.2013.05.052. Epub 2013 Jun 27
Epub:
Not Epub
Abstract:
During embryonic development and tissue homeostasis, cells produce and remodel the extracellular matrix (ECM). The ECM...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725194/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dray N, Lawton A, Nandi A, Jülich D, Emonet T, Holley SA. Cell-fibronectin interactions propel vertebrate trunk elongation via tissue mechanics. Curr Biol. 2013 Jul 22;23(14):1335-41. doi: 10.1016/j.cub.2013.05.052. Epub 2013 Jun 27.

IRE1α knockdown rescues tunicamycin-induced developmental defects and apoptosis in Xenopus laevis

Authors:
Yuan L, Yu J, Li X, Feng J, Yin C, Wang X
Citation:
J Biomed Res. 2014 Jul;28(4):275-81. doi: 10.7555/JBR.28.20120075. Epub 2014 Mar 15
Epub:
Not Epub
Abstract:
Inositol requiring enzyme-1 (IRE1) is highly conserved from yeasts to humans. Upon endoplasmic reticulum (ER) stress, IRE1...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102841/
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yuan L, Yu J, Li X, Feng J, Yin C, Wang X. IRE1α knockdown rescues tunicamycin-induced developmental defects and apoptosis in Xenopus laevis. J Biomed Res. 2014 Jul;28(4):275-81. doi: 10.7555/JBR.28.20120075. Epub 2014 Mar 15.

Modular Evolution of DNA-Binding Preference of a Tbrain Transcription Factor Provides a Mechanism for Modifying Gene Regulatory Networks

Authors:
Cheatle Jarvela AM, Brubaker L, Vedenko A, Gupta A, Armitage BA, Bulyk ML, Hinman VF
Citation:
Mol Biol Evol. 2014 Oct;31(10):2672-88. doi: 10.1093/molbev/msu213. Epub 2014 Jul 12
Epub:
Not Epub
Abstract:
Gene regulatory networks (GRNs) describe the progression of transcriptional states that take a single-celled zygote to a...
Link:
http://mbe.oxfordjournals.org/content/31/10/2672.long
Delivery Method:
microinjection
Organism or Cell Type:
Patiria miniata (sea star)
Citation Extract:
Cheatle Jarvela AM, Brubaker L, Vedenko A, Gupta A, Armitage BA, Bulyk ML, Hinman VF. Modular Evolution of DNA-Binding Preference of a Tbrain Transcription Factor Provides a Mechanism for Modifying Gene Regulatory Networks. Mol Biol Evol. 2014 Oct;31(10):2672-88. doi: 10.1093/molbev/msu213. Epub 2014 Jul 12.

Cholestenoic acids regulate motor neuron survival via liver X receptors

Authors:
Theofilopoulos S, Griffiths WJ, Crick PJ, Yang S, Meljon A, Ogundare M, Kitambi SS, Lockhart A, Tuschl K, Clayton PT, Morris AA, Martinez A, Reddy MA, Martinuzzi A, Bassi MT, Honda A, Mizuochi T, Kimura A, Nittono H, De Michele G, Carbone R, Criscuolo C, Yau JL, Seckl JR, Schüle R, Schöls L, Sailer AW, Kuhle J, Fraidakis MJ, Gustafsson JA, Steffensen KR, Björkhem I, Ernfors P, Sjövall J, Arenas E, Wang Y
Citation:
J Clin Invest. 2014 Oct 1. pii: 68506. doi: 10.1172/JCI68506. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Cholestenoic acids are formed as intermediates in metabolism of cholesterol to bile acids, and the biosynthetic enzymes that...
Link:
http://www.jci.org/articles/view/68506
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Theofilopoulos S, Griffiths WJ, Crick PJ, Yang S, Meljon A, Ogundare M, Kitambi SS, Lockhart A, Tuschl K, Clayton PT, Morris AA, Martinez A, Reddy MA, Martinuzzi A, Bassi MT, Honda A, Mizuochi T, Kimura A, Nittono H, De Michele G, Carbone R, Criscuolo C, Yau JL, Seckl JR, Schüle R, Schöls L, Sailer AW, Kuhle J, Fraidakis MJ, Gustafsson JA, Steffensen KR, Björkhem I, Ernfors P, Sjövall J, Arenas E, Wang Y. Cholestenoic acids regulate motor neuron survival via liver X receptors. J Clin Invest. 2014 Oct 1. pii: 68506. doi: 10.1172/JCI68506. [Epub ahead of print].

Zebrafish cul4a, but not cul4b, modulates cardiac and forelimb development by upregulating tbx5a expression

Authors:
Zhao X, Jiang B, Hu H, Mao F, Mi J, Li Z, Liu Q, Shao C, Gong Y
Citation:
Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu503
Epub:
Not Epub
Abstract:
CUL4A and CUL4B are closely related cullin family members and can each assemble a Cullin-RING E3 ligase complex (CRL) and...
Link:
http://hmg.oxfordjournals.org/content/early/2014/09/30/hmg.ddu503.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao X, Jiang B, Hu H, Mao F, Mi J, Li Z, Liu Q, Shao C, Gong Y. Zebrafish cul4a, but not cul4b, modulates cardiac and forelimb development by upregulating tbx5a expression. Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu503.

Contact-Mediated Inhibition Between Oligodendrocyte Progenitor Cells and Motor Exit Point Glia Establishes the Spinal Cord Transition Zone

Authors:
Smith CJ, Morris AD, Welsh TG, Kucenas S
Citation:
PLoS Biol. 2014;12(9):e1001961. doi:10.1371/journal.pbio.1001961
Epub:
Not Epub
Abstract:
Rapid conduction of action potentials along motor axons requires that oligodendrocytes and Schwann cells myelinate distinct...
Link:
http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1001961
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Smith CJ, Morris AD, Welsh TG, Kucenas S. Contact-Mediated Inhibition Between Oligodendrocyte Progenitor Cells and Motor Exit Point Glia Establishes the Spinal Cord Transition Zone. PLoS Biol. 2014;12(9):e1001961. doi:10.1371/journal.pbio.1001961.

Stage-dependent plasticity of the anterior neural folds to form neural crest

Authors:
Ezin M, Barembaum M, Bronner ME
Citation:
Differentiation. 2014 Sep 25. pii: S0301-4681(14)00053-X. doi: 10.1016/j.diff.2014.09.003. [Epub ahead of print]
Epub:
Yes
Abstract:
The anterior neural fold (ANF) is the only region of the neural tube that does not produce neural crest cells. Instead, ANF...
Link:
http://www.sciencedirect.com/science/article/pii/S030146811400053X
Organism or Cell Type:
chick
Citation Extract:
Ezin M, Barembaum M, Bronner ME. Stage-dependent plasticity of the anterior neural folds to form neural crest. Differentiation. 2014 Sep 25. pii: S0301-4681(14)00053-X. doi: 10.1016/j.diff.2014.09.003. [Epub ahead of print].

Leptin and IL-6 Family Cytokines Synergize to Stimulate Müller Glia Reprogramming and Retina Regeneration

Authors:
Zhao X-F, Wan J, Powell C, Ramachandran R, Myers Jr MG, Goldman D
Citation:
Cell Rep. 2014 Oct 9;9(1):272-84. doi: 10.1016/j.celrep.2014.08.047. Epub 2014 Sep 25.
Epub:
Not Epub
Abstract:
Unlike mammals, zebrafish can regenerate a damaged retina. This remarkable regenerative response is mediated by Müller glia (MG...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4194149/
Delivery Method:
retinal injury & electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao X-F, Wan J, Powell C, Ramachandran R, Myers Jr MG, Goldman D. Leptin and IL-6 Family Cytokines Synergize to Stimulate Müller Glia Reprogramming and Retina Regeneration. Cell Rep. 2014 Oct 9;9(1):272-84. doi: 10.1016/j.celrep.2014.08.047. Epub 2014 Sep 25..

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