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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

G.O.24: Eteplirsen in Duchenne Muscular Dystrophy (DMD): 3year update on Six-Minute Walk Test (6MWT) and Safety

Authors:
Mendell JR, Rodino-Klapac L, Sahenk Z, Roush K, Bird L, Lowes LP, Alfano L, Gomez AM, Lewis S, Malik V, Shontz K, Flanigan KM, Shilling C, Sazani P, Saoud J, Duda P, Kaye E
Citation:
Neuromusc Disord. 2014;24(9):922. doi:10.1016/j.nmd.2014.06.423
Epub:
Not Epub
Abstract:
DMD, a rare, degenerative, genetic disease that results in progressive muscle loss and premature death affects 1:5000 male...
Link:
http://www.nmd-journal.com/article/S0960-8966(14)00574-4/abstract
Delivery Method:
iv infusion
Organism or Cell Type:
human
Citation Extract:
Mendell JR, Rodino-Klapac L, Sahenk Z, Roush K, Bird L, Lowes LP, Alfano L, Gomez AM, Lewis S, Malik V, Shontz K, Flanigan KM, Shilling C, Sazani P, Saoud J, Duda P, Kaye E. G.O.24: Eteplirsen in Duchenne Muscular Dystrophy (DMD): 3year update on Six-Minute Walk Test (6MWT) and Safety. Neuromusc Disord. 2014;24(9):922. doi:10.1016/j.nmd.2014.06.423.

HSPA5 is an essential host factor for Ebola virus infection

Authors:
Patrick Reid S, Shurtleff AC, Costantino JA, Tritsch SR, Retterer C, Spurgers KB, Bavari S
Citation:
Antiviral Res. 2014 Sep;109:171-4. doi: 10.1016/j.antiviral.2014.07.004. Epub 2014 Jul 11
Epub:
Not Epub
Abstract:
Development of novel strategies targeting the highly virulent ebolaviruses is urgently required. A proteomic study identified...
Link:
http://www.sciencedirect.com/science/article/pii/S0166354214002034
Delivery Method:
ip injection
Organism or Cell Type:
mice, cell culture: U2OS reporter cell line
Citation Extract:
Patrick Reid S, Shurtleff AC, Costantino JA, Tritsch SR, Retterer C, Spurgers KB, Bavari S. HSPA5 is an essential host factor for Ebola virus infection. Antiviral Res. 2014 Sep;109:171-4. doi: 10.1016/j.antiviral.2014.07.004. Epub 2014 Jul 11.

CCDC151 Mutations Cause Primary Ciliary Dyskinesia by Disruption of the Outer Dynein Arm Docking Complex Formation

Authors:
Hjeij R, Onoufriadis A, Watson CM, Slagle CE, Klena NT, Dougherty GW, Kurkowiak M, Loges NT, Diggle CP, Morante NFC, Gabriel GC, Lemke KL, Li Y, Pennekamp P, Menchen T, Konert F, Marthin JK, Mans DA, Letteboer SJF, Werner C, Burgoyne T, Westermann C, Rutman A, Carr IM, O’Callaghan C, Moya E, Chung EMK, UK10K Consortium, Sheridan E, Nielsen KG, Roepman R, Bartscherer K, Burdine RD, Lo CW, Omran H, Mitchison HM
Citation:
Am J Hum Genet. 2014;95(3):257-74. doi:10.1016/j.ajhg.2014.08.005
Epub:
Not Epub
Abstract:
A diverse family of cytoskeletal dynein motors powers various cellular transport systems, including axonemal dyneins generating...
Link:
http://www.cell.com/ajhg/abstract/S0002-9297%2814%2900349-8
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hjeij R, Onoufriadis A, Watson CM, Slagle CE, Klena NT, Dougherty GW, Kurkowiak M, Loges NT, Diggle CP, Morante NFC, Gabriel GC, Lemke KL, Li Y, Pennekamp P, Menchen T, Konert F, Marthin JK, Mans DA, Letteboer SJF, Werner C, Burgoyne T, Westermann C, Rutman A, Carr IM, O’Callaghan C, Moya E, Chung EMK, UK10K Consortium, Sheridan E, Nielsen KG, Roepman R, Bartscherer K, Burdine RD, Lo CW, Omran H, Mitchison HM. CCDC151 Mutations Cause Primary Ciliary Dyskinesia by Disruption of the Outer Dynein Arm Docking Complex Formation. Am J Hum Genet. 2014;95(3):257-74. doi:10.1016/j.ajhg.2014.08.005.

Systematic transcriptome analysis of the zebrafish model of diamond-blackfan anemia induced by RPS24 deficiency

Authors:
Song B, Zhang Q, Zhang Z, Wan Y, Jia Q, Wang X, Zhu X, Leung A Y-H, Cheng T, Fang X, Yuan W, Jia H
Citation:
BMC Genomics. 2014;15:759. doi:10.1186/1471-2164-15-759
Epub:
Not Epub
Abstract:
Background: Diamond-Blackfan anemia (DBA) is a class of human diseases linked to defective ribosome biogenesis that results in...
Link:
http://www.biomedcentral.com/1471-2164/15/759/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Song B, Zhang Q, Zhang Z, Wan Y, Jia Q, Wang X, Zhu X, Leung A Y-H, Cheng T, Fang X, Yuan W, Jia H. Systematic transcriptome analysis of the zebrafish model of diamond-blackfan anemia induced by RPS24 deficiency. BMC Genomics. 2014;15:759. doi:10.1186/1471-2164-15-759.

Phosphoproteomics-Mediated Identification of Fer Kinase as a Target of Mutant Shp2 in Noonan and LEOPARD Syndrome

Authors:
Paardekooper Overman J, Preisinger C, Prummel K, Bonetti M, Giansanti P, Heck A, Hertog JD
Citation:
PLoS One. 2014 Sep 3;9(9):e106682. doi: 10.1371/journal.pone.0106682. eCollection 2014
Epub:
Not Epub
Abstract:
Noonan syndrome (NS) and LEOPARD syndrome (LS) cause congenital afflictions such as short stature, hypertelorism and heart...
Link:
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0106682
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Paardekooper Overman J, Preisinger C, Prummel K, Bonetti M, Giansanti P, Heck A, Hertog JD. Phosphoproteomics-Mediated Identification of Fer Kinase as a Target of Mutant Shp2 in Noonan and LEOPARD Syndrome. PLoS One. 2014 Sep 3;9(9):e106682. doi: 10.1371/journal.pone.0106682. eCollection 2014.

Directional Collective Cell Migration Emerges as a Property of Cell Interactions

Authors:
Woods ML, Carmona-Fontaine C, Barnes CP, Couzin ID, Mayor R, Page KM
Citation:
PLoS One. 2014 Sep 2;9(9):e104969. doi: 10.1371/journal.pone.0104969. eCollection 2014
Epub:
Not Epub
Abstract:
Collective cell migration is a fundamental process, occurring during embryogenesis and cancer metastasis. Neural crest cells...
Link:
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0104969#pone-0104969-g006
Organism or Cell Type:
zebrafish
Citation Extract:
Woods ML, Carmona-Fontaine C, Barnes CP, Couzin ID, Mayor R, Page KM. Directional Collective Cell Migration Emerges as a Property of Cell Interactions. PLoS One. 2014 Sep 2;9(9):e104969. doi: 10.1371/journal.pone.0104969. eCollection 2014.

Identification of differentially expressed genes during development of the zebrafish pineal complex using RNA sequencing

Authors:
Khuansuwan S, Gamse JT
Citation:
Dev Biol. 2014 Aug 27. pii: S0012-1606(14)00406-0. doi: 10.1016/j.ydbio.2014.08.015. [Epub ahead of print]
Epub:
Yes
Abstract:
We describe a method for isolating RNA suitable for high-throughput RNA sequencing (RNA-seq) from small numbers of...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160614004060
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Khuansuwan S, Gamse JT. Identification of differentially expressed genes during development of the zebrafish pineal complex using RNA sequencing. Dev Biol. 2014 Aug 27. pii: S0012-1606(14)00406-0. doi: 10.1016/j.ydbio.2014.08.015. [Epub ahead of print].

Functional analysis of hox genes in zebrafish

Authors:
Ladam F, Sagerström CG
Citation:
Methods Mol Biol. 2014;1196:133-44. doi: 10.1007/978-1-4939-1242-1_9
Epub:
Not Epub
Abstract:
The zebrafish model organism is well suited to study the role of specific genes, such as hox genes, in embryogenesis and organ...
Link:
http://link.springer.com/protocol/10.1007%2F978-1-4939-1242-1_9
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ladam F, Sagerström CG. Functional analysis of hox genes in zebrafish. Methods Mol Biol. 2014;1196:133-44. doi: 10.1007/978-1-4939-1242-1_9.

The PDZ-Containing Unconventional Myosin XVIIIA Regulates Embryonic Muscle Integrity in Zebrafish

Authors:
Cao J, Li S, Shao M, Cheng X, Xu Z, Shi D
Citation:
J Genet Genomics. 2014 Aug 20;41(8):417-28. doi: 10.1016/j.jgg.2014.06.008. Epub 2014 Jul 17
Epub:
Not Epub
Abstract:
Myosin XVIIIA, or MYO18A, is a unique PDZ domain-containing unconventional myosin and is evolutionarily conserved from...
Link:
http://www.sciencedirect.com/science/article/pii/S1673852714001210
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cao J, Li S, Shao M, Cheng X, Xu Z, Shi D. The PDZ-Containing Unconventional Myosin XVIIIA Regulates Embryonic Muscle Integrity in Zebrafish. J Genet Genomics. 2014 Aug 20;41(8):417-28. doi: 10.1016/j.jgg.2014.06.008. Epub 2014 Jul 17.

Diverse functions of kindlin/fermitin proteins during embryonic development in Xenopus laevis

Authors:
Rozario T, Mead PE, DeSimone DW
Citation:
Mech Dev. 2014 Aug 27. pii: S0925-4773(14)00037-9. doi: 10.1016/j.mod.2014.07.004. [Epub ahead of print]
Epub:
Yes
Abstract:
The kindlin/fermitin family includes three proteins involved in regulating integrin ligand-binding activity and adhesion. Loss-...
Link:
http://www.sciencedirect.com/science/article/pii/S0925477314000379
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Rozario T, Mead PE, DeSimone DW. Diverse functions of kindlin/fermitin proteins during embryonic development in Xenopus laevis. Mech Dev. 2014 Aug 27. pii: S0925-4773(14)00037-9. doi: 10.1016/j.mod.2014.07.004. [Epub ahead of print].

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