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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Morpholino treatment improves muscle function and pathology of Pitx1 transgenic mice
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Citation:
Mol Ther. 2013 Nov 14. doi: 10.1038/mt.2013.263. [Epub ahead of print] Epub:
Yes Abstract:
Paired-like homeodomain transcription factor 1 (PITX1) was proposed to be part of the disease mechanisms of facioscapulohumeral... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mouse Citation Extract: Pandey SN, Lee YC, Yokota T, Chen YW. Morpholino treatment improves muscle function and pathology of Pitx1 transgenic mice. Mol Ther. 2013 Nov 14. doi: 10.1038/mt.2013.263. [Epub ahead of print]. |
The Integrator Complex Subunit 6 (Ints6) Confines the Dorsal Organizer in Vertebrate Embryogenesis
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Citation:
PLoS Genet. 2013;9(10):e1003822. doi:10.1371/journal.pgen.1003822 Epub:
Not Epub Abstract:
Dorsoventral patterning of the embryonic axis relies upon the mutual antagonism of competing signaling pathways to establish a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kapp LD, Abrams EW, Marlow FL, Mullins MC. The Integrator Complex Subunit 6 (Ints6) Confines the Dorsal Organizer in Vertebrate Embryogenesis. PLoS Genet. 2013;9(10):e1003822. doi:10.1371/journal.pgen.1003822. |
Par6b Regulates the Dynamics of Apicobasal Polarity during Development of the Stratified Xenopus Epidermis
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Citation:
PLoS ONE. 2013;8(10): e76854. doi:10.1371/journal.pone.0076854 Epub:
Not Epub Abstract:
During early vertebrate development, epithelial cells establish and maintain apicobasal polarity, failure of which can cause... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Wang S, Cha S-W, Zorn AM, Wylie C. Par6b Regulates the Dynamics of Apicobasal Polarity during Development of the Stratified Xenopus Epidermis. PLoS ONE. 2013;8(10): e76854. doi:10.1371/journal.pone.0076854. |
Epilepsy in kcnj10 Morphant Zebrafish Assessed with a Novel Method for Long-Term EEG Recordings
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Citation:
PLoS ONE. 2013;8(11):e79765. doi:10.1371/journal.pone.0079765 Epub:
Not Epub Abstract:
We aimed to develop and validate a reliable method for stable long-term recordings of EEG activity in zebrafish, which is less... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zdebik AA, Mahmood F, Stanescu HC, Kleta R, Bockenhauer D, Russell C. Epilepsy in kcnj10 Morphant Zebrafish Assessed with a Novel Method for Long-Term EEG Recordings. PLoS ONE. 2013;8(11):e79765. doi:10.1371/journal.pone.0079765. |
Translation of Human Tissue Factor Pathway Inhibitor-β mRNA Is Controlled by Alternative Splicing Within the 5′ Untranslated Region
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Citation:
Arterioscler Thromb Vasc Biol. 2014 Jan;34(1):187-95. doi: 10.1161/ATVBAHA.113.302660. Epub 2013 Nov 14. Epub:
Yes Abstract:
Objective: Tissue factor pathway inhibitor (TFPI) blocks the initiation of coagulation by inhibiting TF-activated factor VII,... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: MDA-MB-231 cells Citation Extract: Ellery PER, Maroney SA, Martinez ND, Wickens MP, Mast AE. Translation of Human Tissue Factor Pathway Inhibitor-β mRNA Is Controlled by Alternative Splicing Within the 5′ Untranslated Region. Arterioscler Thromb Vasc Biol. 2014 Jan;34(1):187-95. doi: 10.1161/ATVBAHA.113.302660. Epub 2013 Nov 14.. |
Oligonucleotide therapeutics in cancer
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Citation:
Cancer Treat Res. 2013;158:213-33. doi: 10.1007/978-3-642-31659-3_9 Epub:
Not Epub Abstract:
Alterations in pre-mRNA splicing can have profound effects on gene expression and lead to cellular transformation.... Citation Extract: Wan J, Bauman JA, Graziewicz MA, Sazani P, Kole R. Oligonucleotide therapeutics in cancer. Cancer Treat Res. 2013;158:213-33. doi: 10.1007/978-3-642-31659-3_9. |
Podocalyxin regulates pronephric glomerular development in zebrafish
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Citation:
Physiol Rep. 2013 Aug;1(3). doi:pii: e00074 Epub:
Not Epub Abstract:
Vertebrate glomerular podocytes possess a highly sialylated transmembrane glycoprotein, Podocalyxin. In mammals, the sialic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ichimura K, Powell R, Nakamura T, Kurihara H, Sakai T, Obara T. Podocalyxin regulates pronephric glomerular development in zebrafish. Physiol Rep. 2013 Aug;1(3). doi:pii: e00074. |
Piwi regulates Vasa accumulation during embryogenesis in the sea urchin
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Citation:
Dev Dyn. 2013 Nov 12. doi: 10.1002/dvdy.24096. [Epub ahead of print] Epub:
Yes Abstract:
Background: Piwi proteins are essential for germ line development, stem cell maintenance, and more recently found to function... Organism or Cell Type:
Sea urchin: Strongylocentrotus purpuratus Citation Extract: Yajima M, Gustafson EA, Song JL, Wessel GM. Piwi regulates Vasa accumulation during embryogenesis in the sea urchin. Dev Dyn. 2013 Nov 12. doi: 10.1002/dvdy.24096. [Epub ahead of print]. |
A Pou5f1/Oct4 dependent Klf2a, Klf2b, and Klf17 regulatory sub-network contributes to EVL and ectoderm development during zebrafish embryogenesis
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Citation:
Dev Biol. 2013 Nov 5. doi:pii: S0012-1606(13)00580-0. 10.1016/j.ydbio.2013.10.025. [Epub ahead of print] Epub:
Yes Abstract:
In mammalian ES cells, the transcription factors Klf4 and Klf2 contribute to maintenance of pluripotency and self-renewal and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kotkamp K, Mössner R, Allen A, Onichtchouk D, Driever W. A Pou5f1/Oct4 dependent Klf2a, Klf2b, and Klf17 regulatory sub-network contributes to EVL and ectoderm development during zebrafish embryogenesis. Dev Biol. 2013 Nov 5. doi:pii: S0012-1606(13)00580-0. 10.1016/j.ydbio.2013.10.025. [Epub ahead of print]. |
Exome sequencing identifies NBEAL2 as the causative gene for gray platelet syndrome
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Citation:
Nat Genet. 2011 Jul 17;43(8):735-7. doi: 10.1038/ng.885 Epub:
Yes Abstract:
Gray platelet syndrome (GPS) is a predominantly recessive platelet disorder that is characterized by mild thrombocytopenia with... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Albers CA, Cvejic A, Favier R, Bouwmans EE, Alessi MC, Bertone P, Jordan G, Kettleborough RN, Kiddle G, Kostadima M, Read RJ, Sipos B, Sivapalaratnam S, Smethurst PA, Stephens J, Voss K, Nurden A, Rendon A, Nurden P, Ouwehand WH. Exome sequencing identifies NBEAL2 as the causative gene for gray platelet syndrome. Nat Genet. 2011 Jul 17;43(8):735-7. doi: 10.1038/ng.885. |