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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Calcium binding is essential for plastin3 function in Smn-deficient motor neurons

Authors:
Lyon AN, Pineda RH, Hao LT, Kudryashova E, Kudryashov DS, Beattie CE
Citation:
Hum Mol Genet. 2013 Nov 23. [Epub ahead of print]
Epub:
Yes
Abstract:
The actin binding and bundling protein, plastin 3 (PLS3), was identified as a protective modifier of spinal muscular atrophy (...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lyon AN, Pineda RH, Hao LT, Kudryashova E, Kudryashov DS, Beattie CE. Calcium binding is essential for plastin3 function in Smn-deficient motor neurons. Hum Mol Genet. 2013 Nov 23. [Epub ahead of print].

Novel role for carbamoyl phosphate synthetase 2 in cranial sensory circuit formation

Authors:
Cox JA, LaMora A, Johnson SL, Voigt MA
Citation:
Int J Dev Neurosci. 2013;[Epub ahead of print] http://dx.doi.org/10.1016/j.ijdevneu.2013.11.003
Epub:
Not Epub
Abstract:
In zebrafish, cranial sensory circuits form by 4 days post-fertilization. We used a forward genetic screen to identify genes...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cox JA, LaMora A, Johnson SL, Voigt MA. Novel role for carbamoyl phosphate synthetase 2 in cranial sensory circuit formation. Int J Dev Neurosci. 2013;[Epub ahead of print] http://dx.doi.org/10.1016/j.ijdevneu.2013.11.003.

Presynaptic inhibitory actions of pregabalin on excitatory transmission in superficial dorsal horn of mouse spinal cord: Further characterization of presynaptic mechanisms

Authors:
Matsuzawa R, Fujiwara T, Nemoto K, Fukushima T, Yamaguchi S, Akagawa K, Hori Y
Citation:
Neurosci Lett. 2013;[Epub ahead of print] doi:10.1016/j.neulet.2013.11.017
Epub:
Yes
Abstract:
Pregabalin is widely used as an analgesic for the treatment of neuropathic pain. In the present experiments using mouse spinal...
Delivery Method:
intrathecal injection
Organism or Cell Type:
mouse
Citation Extract:
Matsuzawa R, Fujiwara T, Nemoto K, Fukushima T, Yamaguchi S, Akagawa K, Hori Y. Presynaptic inhibitory actions of pregabalin on excitatory transmission in superficial dorsal horn of mouse spinal cord: Further characterization of presynaptic mechanisms. Neurosci Lett. 2013;[Epub ahead of print] doi:10.1016/j.neulet.2013.11.017.

Gene regulatory network for neurogenesis in a sea star embryo connects broad neural specification and localized patterning

Authors:
Yankura KA, Koechlein CS, Cryan AF, Cheatle A, Hinman VF
Citation:
Proc Natl Acad Sci U S A. 2013 May 21;110(21):8591-6. doi: 10.1073/pnas.1220903110. Epub 2013 May 6
Epub:
Not Epub
Abstract:
A great challenge in development biology is to understand how interacting networks of regulatory genes can direct the often...
Delivery Method:
microinjection
Organism or Cell Type:
sea star Patiria miniata
Citation Extract:
Yankura KA, Koechlein CS, Cryan AF, Cheatle A, Hinman VF. Gene regulatory network for neurogenesis in a sea star embryo connects broad neural specification and localized patterning. Proc Natl Acad Sci U S A. 2013 May 21;110(21):8591-6. doi: 10.1073/pnas.1220903110. Epub 2013 May 6.

Hedgehog signaling via a calcitonin receptor-like receptor can induce arterial differentiation independently of VEGF signaling in zebrafish

Authors:
Wilkinson RN, Koudijs MJ, Patient RK, Ingham PW, Schulte-Merker S, van Eeden FJ
Citation:
Blood. 2012 Jul 12;120(2):477-88. doi: 10.1182/blood-2011-10-383729. Epub 2012 Jun 5
Epub:
Not Epub
Abstract:
Multiple signaling pathways control the specification of endothelial cells (ECs) to become arteries or veins during vertebrate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wilkinson RN, Koudijs MJ, Patient RK, Ingham PW, Schulte-Merker S, van Eeden FJ. Hedgehog signaling via a calcitonin receptor-like receptor can induce arterial differentiation independently of VEGF signaling in zebrafish. Blood. 2012 Jul 12;120(2):477-88. doi: 10.1182/blood-2011-10-383729. Epub 2012 Jun 5.

miR-1 and miR-206 target different genes to have opposing roles during angiogenesis in zebrafish embryos

Authors:
Lin CY, Lee HC, Fu CY, Ding YY, Chen JS, Lee MH, Huang WJ, Tsai HJ
Citation:
Nat Commun. 2013 Nov 22;4:2829. doi: 10.1038/ncomms3829
Epub:
Not Epub
Abstract:
As miR-1 and miR-206 share identical seed sequences, they are commonly speculated to target the same gene. Here, we identify an...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin CY, Lee HC, Fu CY, Ding YY, Chen JS, Lee MH, Huang WJ, Tsai HJ. miR-1 and miR-206 target different genes to have opposing roles during angiogenesis in zebrafish embryos. Nat Commun. 2013 Nov 22;4:2829. doi: 10.1038/ncomms3829.

Phosphorylation of angiomotin by Lats1/2 kinases inhibits F-actin binding, cell migration and angiogenesis

Authors:
Dai X, She P, Chi F, Feng Y, Liu H, Jin D, Zhao Y, Guo X, Jiang D, Guan KL, Zhong TP, Zhao B
Citation:
J Biol Chem. 2013 Oct 8. [Epub ahead of print]
Epub:
Yes
Abstract:
The Hippo tumor suppressor pathway plays important roles in organ size control through Lats1/2 mediated phosphorylation of the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dai X, She P, Chi F, Feng Y, Liu H, Jin D, Zhao Y, Guo X, Jiang D, Guan KL, Zhong TP, Zhao B. Phosphorylation of angiomotin by Lats1/2 kinases inhibits F-actin binding, cell migration and angiogenesis. J Biol Chem. 2013 Oct 8. [Epub ahead of print].

The role of cAMP-mediated intracellular signaling in regulating Na+ uptake in zebrafish larvae

Authors:
Kumai Y, Kwong RW, Perry SF
Citation:
Am J Physiol Regul Integr Comp Physiol. 2014 Jan 1;306(1):R51-60. doi: 10.1152/ajpregu.00317.2013. Epub 2013 Nov 20
Epub:
Not Epub
Abstract:
In the current study, the role of cAMP in stimulating Na+ uptake in larval zebrafish was investigated. Treating larvae at 4...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kumai Y, Kwong RW, Perry SF . The role of cAMP-mediated intracellular signaling in regulating Na+ uptake in zebrafish larvae. Am J Physiol Regul Integr Comp Physiol. 2014 Jan 1;306(1):R51-60. doi: 10.1152/ajpregu.00317.2013. Epub 2013 Nov 20.

Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling

Authors:
Wilson CW, Parker LH, Hall CJ, Smyczek T, Mak J, Crow A, Posthuma G, De Mazière A, Sagolla M, Chalouni C, Vitorino P, Roose-Girma M, Warming S, Klumperman J, Crosier PS, Ye W
Citation:
Blood. 2013 Jul 25. [Epub ahead of print]
Epub:
Yes
Abstract:
Establishment and stabilization of endothelial tubes with patent lumens is vital during vertebrate development. Ras-interacting...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wilson CW, Parker LH, Hall CJ, Smyczek T, Mak J, Crow A, Posthuma G, De Mazière A, Sagolla M, Chalouni C, Vitorino P, Roose-Girma M, Warming S, Klumperman J, Crosier PS, Ye W. Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling. Blood. 2013 Jul 25. [Epub ahead of print].

Zinc finger protein 219-like (ZNF219L) and Sox9a regulate synuclein-γ2 (sncgb) expression in the developing notochord of zebrafish

Authors:
Lien H-W, Yang C-H, Cheng C-H, Liao Y-F, Han Y-S, Huang C-J
Citation:
Biochem Biophys Res Comm. 2013;[Epub ahead of print] http://dx.doi.org/10.1016/j.bbrc.2013.11.042
Epub:
Yes
Abstract:
Zebrafish synuclein-γ2 (sncgb) has been reported to be expressed specifically in the notochord. However, the mechanism by which...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lien H-W, Yang C-H, Cheng C-H, Liao Y-F, Han Y-S, Huang C-J. Zinc finger protein 219-like (ZNF219L) and Sox9a regulate synuclein-γ2 (sncgb) expression in the developing notochord of zebrafish. Biochem Biophys Res Comm. 2013;[Epub ahead of print] http://dx.doi.org/10.1016/j.bbrc.2013.11.042.

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