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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Identification of an evx1-Dependent Joint-Formation Pathway during FIN Regeneration

Authors:
Ton QV, Iovine MK
Citation:
PLoS ONE. 2013;8(11):e81240. doi:10.1371/journal.pone.0081240
Epub:
Not Epub
Abstract:
Joints are essential for skeletal flexibly and form, yet the process underlying joint morphogenesis is poorly understood....
Delivery Method:
injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Ton QV, Iovine MK. Identification of an evx1-Dependent Joint-Formation Pathway during FIN Regeneration. PLoS ONE. 2013;8(11):e81240. doi:10.1371/journal.pone.0081240.

Downregulation of max dimerization protein 3 is involved in decreased visceral adipose tissue by inhibiting adipocyte differentiation in zebrafish and mice

Authors:
Shimada Y, Kuroyanagi J, Zhang B, Ariyoshi M, Umemoto N, Nishimura Y, Tanaka T
Citation:
Int J Obes (Lond). 2013 Nov 20. doi: 10.1038/ijo.2013.217. [Epub ahead of print]
Epub:
Yes
Abstract:
Background:The diet-induced obesity model of zebrafish (DIO-zebrafish) shares a common pathophysiological pathway with...
Delivery Method:
i.p. injection
Organism or Cell Type:
zebrafish
Citation Extract:
Shimada Y, Kuroyanagi J, Zhang B, Ariyoshi M, Umemoto N, Nishimura Y, Tanaka T. Downregulation of max dimerization protein 3 is involved in decreased visceral adipose tissue by inhibiting adipocyte differentiation in zebrafish and mice. Int J Obes (Lond). 2013 Nov 20. doi: 10.1038/ijo.2013.217. [Epub ahead of print].

A time delay gene circuit is required for palp formation in the ascidian embryo

Authors:
Ikeda T, Matsuoka T, Satou Y
Citation:
Development. 2013;140:4703-8. doi:10.1242/dev.100339
Epub:
Not Epub
Abstract:
The ascidian larval brain and palps (a putative rudimentary placode) are specified by two transcription factor genes, ZicL and...
Delivery Method:
microinjection
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Ikeda T, Matsuoka T, Satou Y. A time delay gene circuit is required for palp formation in the ascidian embryo. Development. 2013;140:4703-8. doi:10.1242/dev.100339.

A secreted splice variant of the Xenopus frizzled-4 receptor is a biphasic modulator of Wnt signalling

Authors:
Gorny A-K, Kaufmann LT, Swain RK, Steinbeisser H
Citation:
Cell Comm Signaling. 2013;11:89 doi:10.1186/1478-811X-11-89
Epub:
Not Epub
Abstract:
Background: Activation of the Wnt signalling cascade is primarily based on the interplay between Wnt ligands, their receptors...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Gorny A-K, Kaufmann LT, Swain RK, Steinbeisser H. A secreted splice variant of the Xenopus frizzled-4 receptor is a biphasic modulator of Wnt signalling. Cell Comm Signaling. 2013;11:89 doi:10.1186/1478-811X-11-89.

The NADH Oxidase ENOX1, a Critical Mediator of Endothelial Cell Radiosensitivity, is Crucial for Vascular Development

Authors:
Venkateswaran A, Sekhar KR, Levic DS, Melville DB, Clark TA, Rybski WM, Walsh AJ, Skala MC, Crooks PA, Knapik EW, Freeman ML
Citation:
Cancer Res. 2013;[Epub ahead of print]. doi:10.1158/0008-5472.CAN-13-1981
Epub:
Yes
Abstract:
ENOX1 is a highly conserved NADH oxidase that helps to regulate intracellular nicotinamide adenine dinucleotide levels in many...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Venkateswaran A, Sekhar KR, Levic DS, Melville DB, Clark TA, Rybski WM, Walsh AJ, Skala MC, Crooks PA, Knapik EW, Freeman ML. The NADH Oxidase ENOX1, a Critical Mediator of Endothelial Cell Radiosensitivity, is Crucial for Vascular Development. Cancer Res. 2013;[Epub ahead of print]. doi:10.1158/0008-5472.CAN-13-1981.

Rapid positional cloning of zebrafish mutations by linkage and homozygosity mapping using whole-genome sequencing

Authors:
Obholzer N, Swinburne IA, Schwab E, Nechiporuk AV, Nicolson T, Megason SG
Citation:
Development. 2012 Nov;139(22):4280-90. doi: 10.1242/dev.083931. Epub 2012 Oct 10
Epub:
Not Epub
Abstract:
Forward genetic screens in zebrafish have identified >9000 mutants, many of which are potential disease models. Most mutants...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Obholzer N, Swinburne IA, Schwab E, Nechiporuk AV, Nicolson T, Megason SG. Rapid positional cloning of zebrafish mutations by linkage and homozygosity mapping using whole-genome sequencing. Development. 2012 Nov;139(22):4280-90. doi: 10.1242/dev.083931. Epub 2012 Oct 10.

Zebrafish as a novel vertebrate model to dissect enterococcal pathogenesis

Authors:
Prajsnar TK, Renshaw SA, Ogryzko NV, Foster SJ, Serror P, Mesnage S
Citation:
Infect Immun. 2013 Nov;81(11):4271-9. doi: 10.1128/IAI.00976-13. Epub 2013 Sep 3
Epub:
Not Epub
Abstract:
Enterococcus faecalis is an opportunistic pathogen responsible for a wide range of life-threatening nosocomial infections, such...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Prajsnar TK, Renshaw SA, Ogryzko NV, Foster SJ, Serror P, Mesnage S. Zebrafish as a novel vertebrate model to dissect enterococcal pathogenesis. Infect Immun. 2013 Nov;81(11):4271-9. doi: 10.1128/IAI.00976-13. Epub 2013 Sep 3.

Upon Wnt stimulation, Rac1 activation requires Rac1 and Vav2 binding to p120-catenin

Authors:
Valls G, Codina M, Miller RK, Del Valle-Pérez B, Vinyoles M, Caelles C, McCrea PD, García de Herreros A, Duñach M
Citation:
J Cell Sci. 2012 Nov 15;125(Pt 22):5288-301. doi: 10.1242/jcs.101030. Epub 2012 Sep 3
Epub:
Not Epub
Abstract:
A role for Rac1 GTPase in canonical Wnt signaling has recently been demonstrated, showing that it is required for β-catenin...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Valls G, Codina M, Miller RK, Del Valle-Pérez B, Vinyoles M, Caelles C, McCrea PD, García de Herreros A, Duñach M. Upon Wnt stimulation, Rac1 activation requires Rac1 and Vav2 binding to p120-catenin. J Cell Sci. 2012 Nov 15;125(Pt 22):5288-301. doi: 10.1242/jcs.101030. Epub 2012 Sep 3.

Haploinsufficiency of TAB2 causes congenital heart defects in humans

Authors:
Thienpont B, Zhang L, Postma AV, Breckpot J, Tranchevent LC, Van Loo P, Møllgård K, Tommerup N, Bache I, Tümer Z, van Engelen K, Menten B, Mortier G, Waggoner D, Gewillig M, Moreau Y, Devriendt K, Larsen LA
Citation:
Am J Hum Genet. 2010 Jun 11;86(6):839-49. doi: 10.1016/j.ajhg.2010.04.011. Epub 2010 May 20
Epub:
Yes
Abstract:
Congenital heart defects (CHDs) are the most common major developmental anomalies and the most frequent cause for perinatal...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Thienpont B, Zhang L, Postma AV, Breckpot J, Tranchevent LC, Van Loo P, Møllgård K, Tommerup N, Bache I, Tümer Z, van Engelen K, Menten B, Mortier G, Waggoner D, Gewillig M, Moreau Y, Devriendt K, Larsen LA. Haploinsufficiency of TAB2 causes congenital heart defects in humans. Am J Hum Genet. 2010 Jun 11;86(6):839-49. doi: 10.1016/j.ajhg.2010.04.011. Epub 2010 May 20.

Nuclear Wave1 is required for reprogramming transcription in oocytes and for normal development

Authors:
Miyamoto K, Teperek M, Yusa K, Allen GE, Bradshaw CR, Gurdon JB
Citation:
Science. 2013 Aug 30;341(6149):1002-5. doi: 10.1126/science.1240376
Epub:
Yes
Abstract:
Eggs and oocytes have a remarkable ability to induce transcription of sperm after normal fertilization and in somatic nuclei...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Miyamoto K, Teperek M, Yusa K, Allen GE, Bradshaw CR, Gurdon JB. Nuclear Wave1 is required for reprogramming transcription in oocytes and for normal development. Science. 2013 Aug 30;341(6149):1002-5. doi: 10.1126/science.1240376.

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