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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

IRE1α is essential for Xenopus pancreas development

Authors:
Yuan L, Li X, Feng J, Yin C, Yuan F, Wang X
Citation:
J Biomed Res. 2013;28. doi:10.7555/JBR.28. 20130076
Epub:
Not Epub
Abstract:
Inositol requiring enzyme-1 (IRE1) is highly conserved from yeasts to humans. Upon the endoplasmic reticu­lum (ER) stress, IRE1...
Link:
http://www.jbr-pub.org/ch/reader/view_news.aspx?id=20131230052149001####
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yuan L, Li X, Feng J, Yin C, Yuan F, Wang X. IRE1α is essential for Xenopus pancreas development. J Biomed Res. 2013;28. doi:10.7555/JBR.28. 20130076.

Wnt5a uses CD146 as a receptor to regulate cell motility and convergent extension

Authors:
Ye Z, Zhang C, Tu T, Sun M, Liu D, Lu D, Feng J, Yang D, Liu F, Yan X
Citation:
Nat Commun. 2013 Dec 13;4:2803. doi: 10.1038/ncomms3803
Epub:
Not Epub
Abstract:
Dysregulation of Wnt signalling leads to developmental defects and diseases. Non-canonical Wnt signalling via planar cell...
Link:
http://www.nature.com/ncomms/2013/131213/ncomms3803/full/ncomms3803.html
Organism or Cell Type:
zebrafish
Citation Extract:
Ye Z, Zhang C, Tu T, Sun M, Liu D, Lu D, Feng J, Yang D, Liu F, Yan X. Wnt5a uses CD146 as a receptor to regulate cell motility and convergent extension. Nat Commun. 2013 Dec 13;4:2803. doi: 10.1038/ncomms3803.

Transcriptome analysis reveals novel players in the cranial neural crest gene regulatory network

Authors:
Simões-Costa M, Tan-Cabugao J, Antoshechkin I, Sauka-Spengler T, Bronner ME
Citation:
Genome Res. 2014 Jan 3. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The neural crest is an embryonic stem cell population that gives rise to a multitude of derivatives. In particular, the cranial...
Link:
http://genome.cshlp.org/content/early/2014/01/02/gr.161182.113.abstract
Citation Extract:
Simões-Costa M, Tan-Cabugao J, Antoshechkin I, Sauka-Spengler T, Bronner ME. Transcriptome analysis reveals novel players in the cranial neural crest gene regulatory network. Genome Res. 2014 Jan 3. [Epub ahead of print].

Ribosome biogenesis factor Bms1-like is essential for liver development in zebrafish

Authors:
Wang Y, Luo Y, Hong Y, Peng J, Lo L
Citation:
J Genet Genomics. 2012 Sep 20;39(9):451-62. doi: 10.1016/j.jgg.2012.07.007. Epub 2012 Aug 11
Epub:
Not Epub
Abstract:
Ribosome biogenesis in the nucleolus requires numerous nucleolar proteins and small non-coding RNAs. Among them is ribosome...
Link:
ttp://www.sciencedirect.com/science/article/pii/S1673852712001488
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang Y, Luo Y, Hong Y, Peng J, Lo L. Ribosome biogenesis factor Bms1-like is essential for liver development in zebrafish. J Genet Genomics. 2012 Sep 20;39(9):451-62. doi: 10.1016/j.jgg.2012.07.007. Epub 2012 Aug 11.

Therapeutic antagonists of microRNAs deplete leukemia-initiating cell activity

Authors:
Velu CS, Chaubey A, Phelan JD, Horman SR, Wunderlich M, Guzman ML, Jegga AG, Zeleznik-Le NJ, Chen J, Mulloy JC, Cancelas JA, Jordan CT, Aronow BJ, Marcucci G, Bhat B, Gebelein B, Grimes HL
Citation:
J Clin Invest. 2014 Jan 2;124(1):222-36. doi: 10.1172/JCI66005. Epub 2013 Dec 16
Epub:
Not Epub
Abstract:
Acute myelogenous leukemia (AML) subtypes that result from oncogenic activation of homeobox (HOX) transcription factors are...
Link:
http://www.jci.org/articles/view/66005
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: c-Kit+ CD45.1+ CD45.2+ MLL-AF9-initiated leukemia cells
Citation Extract:
Velu CS, Chaubey A, Phelan JD, Horman SR, Wunderlich M, Guzman ML, Jegga AG, Zeleznik-Le NJ, Chen J, Mulloy JC, Cancelas JA, Jordan CT, Aronow BJ, Marcucci G, Bhat B, Gebelein B, Grimes HL. Therapeutic antagonists of microRNAs deplete leukemia-initiating cell activity. J Clin Invest. 2014 Jan 2;124(1):222-36. doi: 10.1172/JCI66005. Epub 2013 Dec 16.

High-resolution imaging of cardiomyocyte behavior reveals two distinct steps in ventricular trabeculation

Authors:
Staudt DW, Liu J, Thorn KS, Stuurman N, Liebling M, Stainier DY
Citation:
Development. 2014 Jan 8. [Epub ahead of print]
Epub:
Yes
Abstract:
Over the course of development, the vertebrate heart undergoes a series of complex morphogenetic processes that transforms it...
Link:
http://dev.biologists.org/content/early/2014/01/08/dev.098632.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Staudt DW, Liu J, Thorn KS, Stuurman N, Liebling M, Stainier DY. High-resolution imaging of cardiomyocyte behavior reveals two distinct steps in ventricular trabeculation. Development. 2014 Jan 8. [Epub ahead of print].

ADAM10 Negatively Regulates Neuronal Differentiation during Spinal Cord Development

Authors:
Yan X, Lin J, Talabattula VA, Mußmann C, Yang F, Wree A, Rolfs A, Luo J
Citation:
PLoS One. 2014 Jan 3;9(1):e84617. doi: 10.1371/journal.pone.0084617
Epub:
Not Epub
Abstract:
Members of the ADAM (a disintegrin and metalloprotease) family are involved in embryogenesis and tissue formation via their...
Link:
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0084617
Delivery Method:
electroporation
Organism or Cell Type:
chick
Citation Extract:
Yan X, Lin J, Talabattula VA, Mußmann C, Yang F, Wree A, Rolfs A, Luo J. ADAM10 Negatively Regulates Neuronal Differentiation during Spinal Cord Development. PLoS One. 2014 Jan 3;9(1):e84617. doi: 10.1371/journal.pone.0084617.

Rab5 and Rab4 Regulate Axon Elongation in the Xenopus Visual System

Authors:
Falk J, Konopacki FA, Zivraj KH, Holt CE
Citation:
J Neurosci. 2014;34(2):373-91; doi:10.1523/JNEUROSCI.0876-13.2014
Epub:
Not Epub
Abstract:
The elongation rate of axons is tightly regulated during development. Recycling of the plasma membrane is known to regulate...
Link:
http://www.jneurosci.org/content/34/2/373.full
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Falk J, Konopacki FA, Zivraj KH, Holt CE. Rab5 and Rab4 Regulate Axon Elongation in the Xenopus Visual System. J Neurosci. 2014;34(2):373-91; doi:10.1523/JNEUROSCI.0876-13.2014.

Loss of col8a1a function during zebrafish embryogenesis results in congenital vertebral malformations

Authors:
Gray RS, Wilm TP, Smith J, Bagnat M, Dale RM, Topczewski J, Johnson SL, Solnica-Krezel L
Citation:
Dev Biol. 2013 Dec 11. pii: S0012-1606(13)00645-3. doi: 10.1016/j.ydbio.2013.11.028. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Congenital vertebral malformations (CVM) occur in 1 in 1000 live births and in many cases can cause spinal deformities, such as...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160613006453
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gray RS, Wilm TP, Smith J, Bagnat M, Dale RM, Topczewski J, Johnson SL, Solnica-Krezel L. Loss of col8a1a function during zebrafish embryogenesis results in congenital vertebral malformations. Dev Biol. 2013 Dec 11. pii: S0012-1606(13)00645-3. doi: 10.1016/j.ydbio.2013.11.028. [Epub ahead of print].

Expression of actin-binding proteins and requirement for actin depolymerizing factor in chick neural crest cells

Authors:
Vermillion KL, Lidberg KA, Gammill LS
Citation:
Dev Dyn. 2014;[Epub ahead of print] doi:10.1002/dvdy.24105
Epub:
Not Epub
Abstract:
Background: Neural crest cells are multipotent cells that migrate extensively throughout vertebrate embryos to form diverse...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/dvdy.24105/abstract
Organism or Cell Type:
chick
Citation Extract:
Vermillion KL, Lidberg KA, Gammill LS. Expression of actin-binding proteins and requirement for actin depolymerizing factor in chick neural crest cells. Dev Dyn. 2014;[Epub ahead of print] doi:10.1002/dvdy.24105.

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