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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

FGF signaling is required for brain left-right asymmetry and brain midline formation

Authors:
Neugebauer JM, Joseph Yost H
Citation:
Dev Biol. 2013 Dec 12. pii: S0012-1606(13)00637-4. doi: 10.1016/j.ydbio.2013.11.020. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Early disruption of FGF signaling alters left-right (LR) asymmetry throughout the embryo. Here we uncover a role for FGF...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Neugebauer JM, Joseph Yost H. FGF signaling is required for brain left-right asymmetry and brain midline formation. Dev Biol. 2013 Dec 12. pii: S0012-1606(13)00637-4. doi: 10.1016/j.ydbio.2013.11.020. [Epub ahead of print].

Knockdown of the germ cell factor Dead end induces multiple transcriptional changes in Atlantic cod (Gadus morhua) hatchlings

Authors:
Škugor A, Tveiten H, Krasnov A, Andersen Ø
Citation:
Anim Rep Sci. 2014;[Epub ahead of print] doi:10.1016/j.anireprosci.2013.12.010
Epub:
Not Epub
Abstract:
The RNA binding protein Dead end (DnD) is essential for maintaining viable germ cells in vertebrates and silencing of the gene...
Delivery Method:
microinjection
Organism or Cell Type:
Gadus morhua (Atlantic cod)
Citation Extract:
Škugor A, Tveiten H, Krasnov A, Andersen Ø. Knockdown of the germ cell factor Dead end induces multiple transcriptional changes in Atlantic cod (Gadus morhua) hatchlings. Anim Rep Sci. 2014;[Epub ahead of print] doi:10.1016/j.anireprosci.2013.12.010.

The Prdm13 histone methyltransferase encoding gene is a Ptf1a-Rbpj downstream target that suppresses glutamatergic and promotes GABAergic neuronal fate in the dorsal neural tube

Authors:
Hanotel J, Bessodes N, Thélie A, Hedderich M, Parain K, Driessche BV, Brandão KD, Kricha S, Jorgensen MC, Grapin-Botton A, Serup P, Lint CV, Perron M, Pieler T, Henningfeld KA, Bellefroid EJ
Citation:
Dev Biol. 2013 Dec 24. pii: S0012-1606(13)00681-7. doi: 10.1016/j.ydbio.2013.12.024. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The basic helix-loop-helix (bHLH) transcriptional activator Ptf1a determines inhibitory GABAergic over excitatory glutamatergic...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Hanotel J, Bessodes N, Thélie A, Hedderich M, Parain K, Driessche BV, Brandão KD, Kricha S, Jorgensen MC, Grapin-Botton A, Serup P, Lint CV, Perron M, Pieler T, Henningfeld KA, Bellefroid EJ. The Prdm13 histone methyltransferase encoding gene is a Ptf1a-Rbpj downstream target that suppresses glutamatergic and promotes GABAergic neuronal fate in the dorsal neural tube. Dev Biol. 2013 Dec 24. pii: S0012-1606(13)00681-7. doi: 10.1016/j.ydbio.2013.12.024. [Epub ahead of print].

Mycobacteria manipulate macrophage recruitment through coordinated use of membrane lipids

Authors:
Cambier CJ, Takaki KK, Larson RP, Hernandez RE, Tobin DM, Urdahl KB, Cosma CL, Ramakrishnan L
Citation:
Nature. 2014 Jan 9;505(7482):218-222. doi: 10.1038/nature12799. Epub 2013 Dec 15
Epub:
Not Epub
Abstract:
The evolutionary survival of Mycobacterium tuberculosis, the cause of human tuberculosis, depends on its ability to invade the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cambier CJ, Takaki KK, Larson RP, Hernandez RE, Tobin DM, Urdahl KB, Cosma CL, Ramakrishnan L. Mycobacteria manipulate macrophage recruitment through coordinated use of membrane lipids. Nature. 2014 Jan 9;505(7482):218-222. doi: 10.1038/nature12799. Epub 2013 Dec 15.

Gas6 Stimulates Angiogenesis of Human Retinal Endothelial Cells and of Zebrafish Embryos via ERK1/2 Signaling

Authors:
Kim YS, Jung S-H, Jung DH, Choi S-J, Lee Y-R, Kim JS
Citation:
PLoS ONE. 2014;9(1): e83901. doi:10.1371/journal.pone.0083901
Epub:
Not Epub
Abstract:
Aim: To determine if growth arrest-specific 6 (Gas6) plays an important role in the regulation of angiogenesis in human retinal...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim YS, Jung S-H, Jung DH, Choi S-J, Lee Y-R, Kim JS. Gas6 Stimulates Angiogenesis of Human Retinal Endothelial Cells and of Zebrafish Embryos via ERK1/2 Signaling. PLoS ONE. 2014;9(1): e83901. doi:10.1371/journal.pone.0083901.

S-Nitrosothiol Signaling Regulates Liver Development and Improves Outcome following Toxic Liver Injury

Authors:
Cox AG, Saunders DC, Kelsey PB Jr, Conway AA, Tesmenitsky Y, Marchini JF, Brown KK, Stamler JS, Colagiovanni DB, Rosenthal GJ, Croce KJ, North TE, Goessling W
Citation:
Cell Rep. 2013 Dec 31. pii: S2211-1247(13)00752-3. doi: 10.1016/j.celrep.2013.12.007. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Toxic liver injury is a leading cause of liver failure and death because of the organ's inability to regenerate amidst...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cox AG, Saunders DC, Kelsey PB Jr, Conway AA, Tesmenitsky Y, Marchini JF, Brown KK, Stamler JS, Colagiovanni DB, Rosenthal GJ, Croce KJ, North TE, Goessling W. S-Nitrosothiol Signaling Regulates Liver Development and Improves Outcome following Toxic Liver Injury. Cell Rep. 2013 Dec 31. pii: S2211-1247(13)00752-3. doi: 10.1016/j.celrep.2013.12.007. [Epub ahead of print].

Transcriptional changes and developmental abnormalities in a zebrafish model of myotonic dystrophy type 1

Authors:
Todd PK, Ackall FY, Hur J, Sharma K, Paulson HL, Dowling JJ
Citation:
Dis Model Mech. 2014 Jan-Feb;7(1):143-55. doi: 10.1242/dmm.012427. Epub 2013 Oct 2
Epub:
Not Epub
Abstract:
Myotonic dystrophy type I (DM1) is a multi-system, autosomal dominant disorder caused by expansion of a CTG repeat sequence in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Todd PK, Ackall FY, Hur J, Sharma K, Paulson HL, Dowling JJ. Transcriptional changes and developmental abnormalities in a zebrafish model of myotonic dystrophy type 1. Dis Model Mech. 2014 Jan-Feb;7(1):143-55. doi: 10.1242/dmm.012427. Epub 2013 Oct 2.

The neuronal co-repressor CoREST: An additional marker for immature neurons within the olfactory epithelium of the developing and adult mouse

Authors:
Lehner C, Wagner A, Tempfer H, Gehwolf R, Bauer H-C
Citation:
J Stem Cells & Regen Med. 2012;8(2):P150
Epub:
Not Epub
Abstract:
Heart failure due to the loss of functional cardiomyocytes is one of the most frequent cardiovascular diseases. Understanding...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lehner C, Wagner A, Tempfer H, Gehwolf R, Bauer H-C. The neuronal co-repressor CoREST: An additional marker for immature neurons within the olfactory epithelium of the developing and adult mouse. J Stem Cells & Regen Med. 2012;8(2):P150.

Differential activation of natriuretic peptide receptors modulates cardiomyocyte proliferation during development

Authors:
Becker JR, Chatterjee S, Robinson TY, Bennett JS, Panáková D, Galindo CL, Zhong L, Shin JT, Coy SM, Kelly AE, Roden DM, Lim CC, Macrae CA
Citation:
Development. 2014 Jan;141(2):335-45. doi: 10.1242/dev.100370. Epub 2013 Dec 18
Epub:
Not Epub
Abstract:
Organ development is a highly regulated process involving the coordinated proliferation and differentiation of diverse cellular...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Becker JR, Chatterjee S, Robinson TY, Bennett JS, Panáková D, Galindo CL, Zhong L, Shin JT, Coy SM, Kelly AE, Roden DM, Lim CC, Macrae CA. Differential activation of natriuretic peptide receptors modulates cardiomyocyte proliferation during development. Development. 2014 Jan;141(2):335-45. doi: 10.1242/dev.100370. Epub 2013 Dec 18.

Myomasp/LRRC39, a heart- and muscle-specific protein, is a novel component of the sarcomeric M-band and is involved in stretch sensing

Authors:
Will RD, Eden M, Just S, Hansen A, Eder A, Frank D, Kuhn C, Seeger TS, Oehl U, Wiemann S, Korn B, Koegl M, Rottbauer W, Eschenhagen T, Katus HA, Frey N
Citation:
Circ Res. 2010 Nov 12;107(10):1253-64. doi: 10.1161/CIRCRESAHA.110.222372. Epub 2010 Sep 16
Epub:
Not Epub
Abstract:
RATIONALE AND OBJECTIVE: The M-band represents a transverse structure in the center of the sarcomeric A-band and provides an...
Delivery Method:
microinjection
Organism or Cell Type:
z
Citation Extract:
Will RD, Eden M, Just S, Hansen A, Eder A, Frank D, Kuhn C, Seeger TS, Oehl U, Wiemann S, Korn B, Koegl M, Rottbauer W, Eschenhagen T, Katus HA, Frey N. Myomasp/LRRC39, a heart- and muscle-specific protein, is a novel component of the sarcomeric M-band and is involved in stretch sensing. Circ Res. 2010 Nov 12;107(10):1253-64. doi: 10.1161/CIRCRESAHA.110.222372. Epub 2010 Sep 16.

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