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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Essential role of AWP1 in neural crest specification in Xenopus

Authors:
Seo J-H, Park D-S, Hong M, Chang E-J, Choi S-C
Citation:
Int J Dev Biol. 2014;[Epub ahead of print] doi:10.1387/ijdb.130109sc
Epub:
Yes
Abstract:
The neural crest (NC) comprises a transient and multipotent embryonic cell population, which gives rise to a wide variety of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Seo J-H, Park D-S, Hong M, Chang E-J, Choi S-C. Essential role of AWP1 in neural crest specification in Xenopus. Int J Dev Biol. 2014;[Epub ahead of print] doi:10.1387/ijdb.130109sc.

Novel Ex Vivo Culture Method for the Study of Dupuytren's Disease: Effects of TGFβ Type 1 Receptor Modulation by Antisense Oligonucleotides

Authors:
Karkampouna S, Kruithof BP, Kloen P, Obdeijn MC, van der Laan AM, Tanke HJ, Kemaladewi DU, Hoogaars WM, 't Hoen PA, Aartsma-Rus A, Clark IM, Ten Dijke P, Goumans MJ, Kruithof-de Julio M
Citation:
Mol Ther Nucleic Acids. 2014 Jan 21;3:e142. doi: 10.1038/mtna.2013.69
Epub:
Not Epub
Abstract:
Dupuytren's disease (DD) is a benign fibroproliferative disease of the hand. It is characterized by the excessive...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Human explant cultures
Citation Extract:
Karkampouna S, Kruithof BP, Kloen P, Obdeijn MC, van der Laan AM, Tanke HJ, Kemaladewi DU, Hoogaars WM, 't Hoen PA, Aartsma-Rus A, Clark IM, Ten Dijke P, Goumans MJ, Kruithof-de Julio M. Novel Ex Vivo Culture Method for the Study of Dupuytren's Disease: Effects of TGFβ Type 1 Receptor Modulation by Antisense Oligonucleotides. Mol Ther Nucleic Acids. 2014 Jan 21;3:e142. doi: 10.1038/mtna.2013.69.

Essential role of SH3-domain GRB2-like 3 for vascular lumen maintenance in zebrafish

Authors:
Zhao Y, Lin S
Citation:
Arterioscler Thromb Vasc Biol. 2013 Jun;33(6):1280-6. doi: 10.1161/ATVBAHA.112.301025. Epub 2013 Mar 28
Epub:
Not Epub
Abstract:
OBJECTIVE: Studying the underlying molecular mechanisms for maintaining stereotyped vascular lumen diameters should help toward...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao Y, Lin S. Essential role of SH3-domain GRB2-like 3 for vascular lumen maintenance in zebrafish. Arterioscler Thromb Vasc Biol. 2013 Jun;33(6):1280-6. doi: 10.1161/ATVBAHA.112.301025. Epub 2013 Mar 28.

Molecular cloning and knockdown of galactocerebrosidase in zebrafish: New insights into the pathogenesis of Krabbe’s disease

Authors:
Zizioli D, Guarienti M, Tobia C, Gariano G, Borsani G, Bresciani R, Ronca R, Giacopuzzi E, Preti A, Gaudenzi G, Belleri M, Di Salle E, Fabrias G, Casas J, Ribatti D, Monti E, Presta M
Citation:
Biochim Biophys Acta. 2014;[Epub ahead of print] http://dx.doi.org/10.1016/j.bbadis.2014.01.008
Epub:
Yes
Abstract:
The lysosomal hydrolase galactocerebrosidase (GALC) catalyzes the removal of galactose from galactosylceramide and from other...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zizioli D, Guarienti M, Tobia C, Gariano G, Borsani G, Bresciani R, Ronca R, Giacopuzzi E, Preti A, Gaudenzi G, Belleri M, Di Salle E, Fabrias G, Casas J, Ribatti D, Monti E, Presta M. Molecular cloning and knockdown of galactocerebrosidase in zebrafish: New insights into the pathogenesis of Krabbe’s disease. Biochim Biophys Acta. 2014;[Epub ahead of print] http://dx.doi.org/10.1016/j.bbadis.2014.01.008.

Expression and Functional Characterization of Smyd1a in Myofibril Organization of Skeletal Muscles

Authors:
Gao J, Li J, Li B-J, Yagil E, Zhang J, Du SJ
Citation:
PLoS ONE. 2014;9(1): e86808. doi:10.1371/journal.pone.0086808
Epub:
Not Epub
Abstract:
Background: Smyd1, the founding member of the Smyd family including Smyd-1, 2, 3, 4 and 5, is a SET and MYND domain containing...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gao J, Li J, Li B-J, Yagil E, Zhang J, Du SJ. Expression and Functional Characterization of Smyd1a in Myofibril Organization of Skeletal Muscles. PLoS ONE. 2014;9(1): e86808. doi:10.1371/journal.pone.0086808.

Interplay between pre-mRNA splicing and microRNA biogenesis within the supraspliceosome

Authors:
Agranat-Tamir L, Shomron N, Sperling J, Sperling R
Citation:
Nucl Acids Res. 2014;[Epub ahead of print] doi:10.1093/nar/gkt1413
Epub:
Yes
Abstract:
MicroRNAs (miRNAs) are central regulators of gene expression, and a large fraction of them are encoded in introns of RNA...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HeLa
Citation Extract:
Agranat-Tamir L, Shomron N, Sperling J, Sperling R. Interplay between pre-mRNA splicing and microRNA biogenesis within the supraspliceosome. Nucl Acids Res. 2014;[Epub ahead of print] doi:10.1093/nar/gkt1413 .

Overexpression of autotaxin, a lysophosphatidic acid-producing enzyme, enhances cardia bifida induced by hypo-sphingosine-1-phosphate signaling in zebrafish embryo

Authors:
Nakanaga K, Hama K, Kano K, Sato T, Yukiura H, Inoue A, Saigusa D, Tokuyama H, Tomioka Y, Nishina H, Kawahara A, Aoki J
Citation:
J Biochem. 2014 Jan 21. [Epub ahead of print]
Epub:
Yes
Abstract:
Lysophosphatidic acid (LPA) and sphingosine-1-phosphate (S1P) are second-generation lysophospholipid mediators that exert...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nakanaga K, Hama K, Kano K, Sato T, Yukiura H, Inoue A, Saigusa D, Tokuyama H, Tomioka Y, Nishina H, Kawahara A, Aoki J. Overexpression of autotaxin, a lysophosphatidic acid-producing enzyme, enhances cardia bifida induced by hypo-sphingosine-1-phosphate signaling in zebrafish embryo. J Biochem. 2014 Jan 21. [Epub ahead of print].

The Nogo-C2/Nogo Receptor Complex Regulates the Morphogenesis of Zebrafish Lateral Line Primordium through Modulating the Expression of dkk1b, a Wnt Signal Inhibitor

Authors:
Han H-W, Chou C-M, Chu C-Y, Cheng C-H, Yang C-H, Hung C-C, Hwang P-P, Lee S-J, Liao Y-F, Huang C-J
Citation:
PLoS ONE. 2014;9(1):e86345. doi:10.1371/journal.pone.0086345
Epub:
Not Epub
Abstract:
The fish lateral line (LL) is a mechanosensory system closely related to the hearing system of higher vertebrates, and it is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Han H-W, Chou C-M, Chu C-Y, Cheng C-H, Yang C-H, Hung C-C, Hwang P-P, Lee S-J, Liao Y-F, Huang C-J. The Nogo-C2/Nogo Receptor Complex Regulates the Morphogenesis of Zebrafish Lateral Line Primordium through Modulating the Expression of dkk1b, a Wnt Signal Inhibitor. PLoS ONE. 2014;9(1):e86345. doi:10.1371/journal.pone.0086345.

Zebrafish eaf1 Suppresses foxo3b Expression to Modulate Transcriptional Activity of gata1 and spi1 in Primitive Hematopoiesis

Authors:
Hu B, Zhang W, Feng X, Ji W, Xie X, Xiao W
Citation:
Dev Biol. 2014 Apr 1;388(1):81-93. doi: 10.1016/j.ydbio.2014.01.005. Epub 2014 Jan 17
Epub:
Not Epub
Abstract:
Studies implicate a potential role for EAF1 in MLL-ELL induced leukemogenesis; however the biological function of EAF1 in this...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hu B, Zhang W, Feng X, Ji W, Xie X, Xiao W. Zebrafish eaf1 Suppresses foxo3b Expression to Modulate Transcriptional Activity of gata1 and spi1 in Primitive Hematopoiesis. Dev Biol. 2014 Apr 1;388(1):81-93. doi: 10.1016/j.ydbio.2014.01.005. Epub 2014 Jan 17.

Endocytosis of Fgf8 Is a Double-Stage Process and Regulates Spreading and Signaling

Authors:
Rengarajan C, Matzke A, Reiner L, Orian-Rousseau V, Scholpp S
Citation:
PLoS ONE. 2014;9(1):e86373. doi:10.1371/journal.pone.0086373
Epub:
Not Epub
Abstract:
Tightly controlled concentration gradients of morphogens provide positional information and thus regulate tissue...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rengarajan C, Matzke A, Reiner L, Orian-Rousseau V, Scholpp S. Endocytosis of Fgf8 Is a Double-Stage Process and Regulates Spreading and Signaling. PLoS ONE. 2014;9(1):e86373. doi:10.1371/journal.pone.0086373.

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