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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

A non-canonical function of telomerase RNA in the regulation of developmental myelopoiesis in zebrafish

Authors:
Alcaraz-Pérez F, García-Castillo J, García-Moreno D, López-Muñoz A, Anchelin M, Angosto D, Zon LI, Mulero V, Cayuela ML
Citation:
Nat Commun. 2014 Feb 5;5:3228. doi: 10.1038/ncomms4228
Epub:
Not Epub
Abstract:
Dyskeratosis congenita (DC) is an inherited disorder with mutations affecting telomerase or telomeric proteins. DC patients...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Alcaraz-Pérez F, García-Castillo J, García-Moreno D, López-Muñoz A, Anchelin M, Angosto D, Zon LI, Mulero V, Cayuela ML. A non-canonical function of telomerase RNA in the regulation of developmental myelopoiesis in zebrafish. Nat Commun. 2014 Feb 5;5:3228. doi: 10.1038/ncomms4228.

PCP and septins compartmentalize cortical actomyosin to direct collective cell movement

Authors:
Shindo A, Wallingford JB
Citation:
Science. 2014 Feb 7;343(6171):649-52. doi: 10.1126/science.1243126
Epub:
Not Epub
Abstract:
Despite our understanding of actomyosin function in individual migrating cells, we know little about the mechanisms by which...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Shindo A, Wallingford JB. PCP and septins compartmentalize cortical actomyosin to direct collective cell movement. Science. 2014 Feb 7;343(6171):649-52. doi: 10.1126/science.1243126.

An essential role for LPA signalling in telencephalon development

Authors:
Geach TJ, Faas L, Devader C, Gonzalez-Cordero A, Tabler JM, Brunsdon H, Isaacs HV, Dale L
Citation:
Development. 2014 Feb;141(4):940-9. doi: 10.1242/dev.104901
Epub:
Not Epub
Abstract:
Lysophosphatidic acid (LPA) has wide-ranging effects on many different cell types, acting through G-protein-coupled receptors...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Geach TJ, Faas L, Devader C, Gonzalez-Cordero A, Tabler JM, Brunsdon H, Isaacs HV, Dale L. An essential role for LPA signalling in telencephalon development. Development. 2014 Feb;141(4):940-9. doi: 10.1242/dev.104901.

Impaired embryonic motility in dusp27 mutants reveals a developmental defect in myofibril structure

Authors:
Fero K, Bergeron SA, Horstick EJ, Codore H, Li GH, Ono F, Dowling JJ, Burgess HA
Citation:
Dis Model Mech. 2013 Nov 7. [Epub ahead of print]
Epub:
Yes
Abstract:
An essential step in muscle fiber maturation is the assembly of highly ordered myofibrils that are required for contraction....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fero K, Bergeron SA, Horstick EJ, Codore H, Li GH, Ono F, Dowling JJ, Burgess HA. Impaired embryonic motility in dusp27 mutants reveals a developmental defect in myofibril structure. Dis Model Mech. 2013 Nov 7. [Epub ahead of print].

PV.1 induced by FGF-Xbra functions as a repressor of neurogenesis in Xenopus embryos

Authors:
Yoon J, Kim JH, Lee SY, Kim S, Park JB, Lee JY, Kim J
Citation:
BMB Rep. 2014 Feb 6. pii: 2608. [Epub ahead of print]
Epub:
Yes
Abstract:
During Xenopus early development, FGF signaling is involved in mesoderm formation and neurogenesis by modulating various...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yoon J, Kim JH, Lee SY, Kim S, Park JB, Lee JY, Kim J. PV.1 induced by FGF-Xbra functions as a repressor of neurogenesis in Xenopus embryos. BMB Rep. 2014 Feb 6. pii: 2608. [Epub ahead of print].

Differential Skeletal Muscle Proteome of High and Low Active mice

Authors:
Ferguson DP, Dangott LJ, Schmitt EE, Vellers HL, Lightfoot JT
Citation:
J Appl Physiol. 1985. 2014 Feb 6. [Epub ahead of print]
Epub:
Yes
Abstract:
Physical inactivity contributes to cardiovascular disease, type II diabetes, obesity and some types of cancer. While the...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mouse
Citation Extract:
Ferguson DP, Dangott LJ, Schmitt EE, Vellers HL, Lightfoot JT. Differential Skeletal Muscle Proteome of High and Low Active mice. J Appl Physiol. 1985. 2014 Feb 6. [Epub ahead of print].

Expression and function of transcription factor cMyb during cranial neural crest development

Authors:
Betancur P, Simões-Costa M, Sauka-Spengler T, Bronner ME
Citation:
Mech Dev. 2014;[Epub ahead of print] doi:10.1016/j.mod.2014.01.005
Epub:
Yes
Abstract:
The transcription factor cMyb has well known functions in vertebrate hematopoiesis, but little was known about its distribution...
Organism or Cell Type:
chick
Citation Extract:
Betancur P, Simões-Costa M, Sauka-Spengler T, Bronner ME. Expression and function of transcription factor cMyb during cranial neural crest development. Mech Dev. 2014;[Epub ahead of print] doi:10.1016/j.mod.2014.01.005.

The Heterochronic Genes lin-28a and lin-28b Play an Essential and Evolutionarily Conserved Role in Early Zebrafish Development

Authors:
Ouchi Y, Yamamoto J, Iwamoto T
Citation:
PLoS ONE. 2014;9(2):e88086. doi:10.1371/journal.pone.0088086
Epub:
Not Epub
Abstract:
The Caenorhabditis elegans heterochronic gene pathway, which consists of a set of regulatory genes, plays an important...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ouchi Y, Yamamoto J, Iwamoto T. The Heterochronic Genes lin-28a and lin-28b Play an Essential and Evolutionarily Conserved Role in Early Zebrafish Development. PLoS ONE. 2014;9(2):e88086. doi:10.1371/journal.pone.0088086.

Interdependence of Bad and Puma during Ionizing-Radiation-Induced Apoptosis

Authors:
Toruno C, Carbonneau S, Stewart RA, Jette C
Citation:
PLoS ONE. 2014;9(2):e88151. doi:10.1371/journal.pone.0088151
Epub:
Not Epub
Abstract:
Ionizing radiation (IR)-induced DNA double-strand breaks trigger an extensive cellular signaling response that involves the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Toruno C, Carbonneau S, Stewart RA, Jette C. Interdependence of Bad and Puma during Ionizing-Radiation-Induced Apoptosis. PLoS ONE. 2014;9(2):e88151. doi:10.1371/journal.pone.0088151.

Antisense suppression of donor splice site mutations in the dystrophin gene transcript

Authors:
Fletcher S, Meloni PL, Johnsen RD, Wong BL, Muntoni F, Wilton SD
Citation:
Mol Genet Genomic Med. 2013 Sep;1(3):162-73. doi: 10.1002/mgg3.19. Epub 2013 Jun 13
Epub:
Not Epub
Abstract:
We describe two donor splice site mutations, affecting dystrophin exons 16 and 45 that led to Duchenne muscular dystrophy (DMD...
Delivery Method:
peptide-linked
Organism or Cell Type:
Primary DMD human cells underwent forced myogenesis
Citation Extract:
Fletcher S, Meloni PL, Johnsen RD, Wong BL, Muntoni F, Wilton SD. Antisense suppression of donor splice site mutations in the dystrophin gene transcript. Mol Genet Genomic Med. 2013 Sep;1(3):162-73. doi: 10.1002/mgg3.19. Epub 2013 Jun 13.

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