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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Aminolevulinate synthase 2 mediates erythrocyte differentiation by regulating larval globin expression during Xenopus primary hematopoiesis

Authors:
Ogawa-Otomo A, Kurisaki A, Ito Y
Citation:
Biochem Biophys Res Commun. 2014 Dec 4. pii: S0006-291X(14)02151-2. doi: 10.1016/j.bbrc.2014.11.110. [Epub ahead of print]
Epub:
Yes
Abstract:
Hemoglobin synthesis by erythrocytes continues throughout a vertebrate's lifetime. The mechanism of mammalian heme...
Link:
http://www.sciencedirect.com/science/article/pii/S0006291X14021512
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ogawa-Otomo A, Kurisaki A, Ito Y. Aminolevulinate synthase 2 mediates erythrocyte differentiation by regulating larval globin expression during Xenopus primary hematopoiesis. Biochem Biophys Res Commun. 2014 Dec 4. pii: S0006-291X(14)02151-2. doi: 10.1016/j.bbrc.2014.11.110. [Epub ahead of print].

Neuropathy target esterase impairments cause Oliver-McFarlane and Laurence-Moon syndromes

Authors:
Hufnagel RB, Arno G, Hein ND, Hersheson J, Prasad M, Anderson Y, Krueger LA, Gregory LC, Stoetzel C, Jaworek TJ, Hull S, Li A, Plagnol V, Willen CM, Morgan TM, Prows CA, Hegde RS, Riazuddin S, Grabowski GA, Richardson RJ, Dieterich K, Huang T, Revesz T, Martinez-Barbera JP, Sisk RA, Jefferies C, Houlden H, Dattani MT, Fink JK, Dollfus H, Moore AT, Ahmed ZM
Citation:
J Med Genet. 2014 Dec 5. pii: jmedgenet-2014-102856. doi: 10.1136/jmedgenet-2014-102856. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: Oliver-McFarlane syndrome is characterised by trichomegaly, congenital hypopituitarism and retinal degeneration...
Link:
http://jmg.bmj.com/content/early/2014/12/05/jmedgenet-2014-102856.abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Hufnagel RB, Arno G, Hein ND, Hersheson J, Prasad M, Anderson Y, Krueger LA, Gregory LC, Stoetzel C, Jaworek TJ, Hull S, Li A, Plagnol V, Willen CM, Morgan TM, Prows CA, Hegde RS, Riazuddin S, Grabowski GA, Richardson RJ, Dieterich K, Huang T, Revesz T, Martinez-Barbera JP, Sisk RA, Jefferies C, Houlden H, Dattani MT, Fink JK, Dollfus H, Moore AT, Ahmed ZM. Neuropathy target esterase impairments cause Oliver-McFarlane and Laurence-Moon syndromes. J Med Genet. 2014 Dec 5. pii: jmedgenet-2014-102856. doi: 10.1136/jmedgenet-2014-102856. [Epub ahead of print].

In vivo loss of function study reveals the short stature homeobox-containing (shox) gene plays indispensable roles in early embryonic growth and bone formation in zebrafish

Authors:
Sawada R, Kamei H, Hakuno F, Takahashi SI, Shimizu T
Citation:
Dev Dyn. 2014 Dec 8. doi: 10.1002/dvdy.24239. [Epub ahead of print]
Epub:
Yes
Abstract:
Background: Congenital loss of the SHOX gene is considered to be a genetic cause of short stature phenotype in Turner syndrome...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/dvdy.24239/abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Sawada R, Kamei H, Hakuno F, Takahashi SI, Shimizu T. In vivo loss of function study reveals the short stature homeobox-containing (shox) gene plays indispensable roles in early embryonic growth and bone formation in zebrafish. Dev Dyn. 2014 Dec 8. doi: 10.1002/dvdy.24239. [Epub ahead of print].

Zebrafish Rab5 proteins and a role for Rab5ab in nodal signalling

Authors:
Kenyon EJ, Campos I, Bull JC, Williams PH, Stemple DL, Clark MD
Citation:
Dev Biol. 2014 Dec 3. pii: S0012-1606(14)00584-3. doi: 10.1016/j.ydbio.2014.11.007. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The RAB5 gene family is the best characterised of all human RAB families and is essential for in vitro homotypic fusion of...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160614005843
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kenyon EJ, Campos I, Bull JC, Williams PH, Stemple DL, Clark MD. Zebrafish Rab5 proteins and a role for Rab5ab in nodal signalling. Dev Biol. 2014 Dec 3. pii: S0012-1606(14)00584-3. doi: 10.1016/j.ydbio.2014.11.007. [Epub ahead of print].

CTNND2-a candidate gene for reading problems and mild intellectual disability

Authors:
Hofmeister W, Nilsson D, Topa A, Anderlid BM, Darki F, Matsson H, Tapia Páez I, Klingberg T, Samuelsson L, Wirta V, Vezzi F, Kere J, Nordenskjöld M, Syk Lundberg E, Lindstrand A
Citation:
J Med Genet. 2014 Dec 3. pii: jmedgenet-2014-102757. doi: 10.1136/jmedgenet-2014-102757. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: Cytogenetically visible chromosomal translocations are highly informative as they can pinpoint strong effect genes...
Link:
http://jmg.bmj.com/content/early/2014/12/03/jmedgenet-2014-102757.abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Hofmeister W, Nilsson D, Topa A, Anderlid BM, Darki F, Matsson H, Tapia Páez I, Klingberg T, Samuelsson L, Wirta V, Vezzi F, Kere J, Nordenskjöld M, Syk Lundberg E, Lindstrand A. CTNND2-a candidate gene for reading problems and mild intellectual disability. J Med Genet. 2014 Dec 3. pii: jmedgenet-2014-102757. doi: 10.1136/jmedgenet-2014-102757. [Epub ahead of print].

The amniote primitive streak is defined by epithelial cell intercalation before gastrulation

Authors:
Voiculescu O, Bertocchini F, Wolpert L, Keller RE, Stern CD
Citation:
Nature. 2007 Oct 25;449(7165):1049-52. Epub 2007 Oct 10.
Epub:
Not Epub
Abstract:
During gastrulation, a single epithelial cell layer, the ectoderm, generates two others: the mesoderm and the endoderm. In...
Link:
http://www.nature.com/nature/journal/v449/n7165/full/nature06211.html
Delivery Method:
electroporation
Organism or Cell Type:
chick
Citation Extract:
Voiculescu O, Bertocchini F, Wolpert L, Keller RE, Stern CD. The amniote primitive streak is defined by epithelial cell intercalation before gastrulation. Nature. 2007 Oct 25;449(7165):1049-52. Epub 2007 Oct 10..

RGM Regulates BMP-Mediated Secondary Axis Formation in the Sea Anemone Nematostella vectensis

Authors:
Leclère L, Rentzsch F
Citation:
Cell Rep. 2014;[Epub ahead of print] doi:10.1016/j.celrep.2014.11.009
Epub:
Yes
Abstract:
Patterning of the metazoan dorsoventral axis is mediated by a complex interplay of BMP signaling regulators. Repulsive guidance...
Link:
http://www.cell.com/cell-reports/abstract/S2211-1247(14)00963-2
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (cnidarian)
Citation Extract:
Leclère L, Rentzsch F. RGM Regulates BMP-Mediated Secondary Axis Formation in the Sea Anemone Nematostella vectensis. Cell Rep. 2014;[Epub ahead of print] doi:10.1016/j.celrep.2014.11.009.

Characterization of an apparently synonymous F5 mutation causing aberrant splicing and factor V deficiency

Authors:
Nuzzo F, Bulato C, Nielsen BI, Lee K, Wielders SJ, Simioni P, Key NS, Castoldi E
Citation:
Haemophilia. 2014 Dec 3. doi: 10.1111/hae.12554. [Epub ahead of print]
Epub:
Yes
Abstract:
Coagulation factor V (FV) deficiency is a rare autosomal recessive bleeding disorder. We investigated a patient with severe FV...
Link:
http://onlinelibrary.wiley.com/doi/10.1111/hae.12554/abstract
Citation Extract:
Nuzzo F, Bulato C, Nielsen BI, Lee K, Wielders SJ, Simioni P, Key NS, Castoldi E. Characterization of an apparently synonymous F5 mutation causing aberrant splicing and factor V deficiency. Haemophilia. 2014 Dec 3. doi: 10.1111/hae.12554. [Epub ahead of print].

Both the folate cycle and betaine-homocysteine methyltransferase contribute methyl groups for DNA methylation in mouse blastocysts

Authors:
Zhang B, Denomme MM, White CR, Leung KY, Lee MB, Greene ND, Mann MR, Trasler JM, Baltz JM
Citation:
FASEB J. 2014 Dec 2. pii: fj.14-261131. [Epub ahead of print]
Epub:
Yes
Abstract:
The embryonic pattern of global DNA methylation is first established in the inner cell mass (ICM) of the mouse blastocyst. The...
Link:
http://www.fasebj.org/content/early/2014/11/25/fj.14-261131.abstract
Delivery Method:
Lipofectin
Organism or Cell Type:
Eight-cell stage mouse embryos
Citation Extract:
Zhang B, Denomme MM, White CR, Leung KY, Lee MB, Greene ND, Mann MR, Trasler JM, Baltz JM. Both the folate cycle and betaine-homocysteine methyltransferase contribute methyl groups for DNA methylation in mouse blastocysts. FASEB J. 2014 Dec 2. pii: fj.14-261131. [Epub ahead of print].

DNA methyltransferase 3B regulates duration of neural crest production via repression of Sox10

Authors:
Hu N, Strobl-Mazzulla PH, Simoes-Costa M, Sánchez-Vásquez E, Bronner ME
Citation:
Proc Natl Acad Sci U S A. 2014 Dec 1. pii: 201318408. [Epub ahead of print]
Epub:
Yes
Abstract:
Neural crest stem cells arise within the central nervous system but then undergo an epithelial-to-mesenchymal transition to...
Link:
http://www.pnas.org/content/early/2014/11/26/1318408111.abstract
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Hu N, Strobl-Mazzulla PH, Simoes-Costa M, Sánchez-Vásquez E, Bronner ME. DNA methyltransferase 3B regulates duration of neural crest production via repression of Sox10. Proc Natl Acad Sci U S A. 2014 Dec 1. pii: 201318408. [Epub ahead of print].

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