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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Zebrafish pronephros tubulogenesis and epithelial identity maintenance are reliant on the polarity proteins Prkc iota and zeta
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Citation:
Dev Biol. 2014 Oct 14. pii: S0012-1606(14)00502-8. doi: 10.1016/j.ydbio.2014.08.038. [Epub ahead of print] Epub:
Yes Abstract:
The zebrafish pronephros provides an excellent in vivo system to study the mechanisms of vertebrate nephron development. When... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gerlach GF, Wingert RA. Zebrafish pronephros tubulogenesis and epithelial identity maintenance are reliant on the polarity proteins Prkc iota and zeta. Dev Biol. 2014 Oct 14. pii: S0012-1606(14)00502-8. doi: 10.1016/j.ydbio.2014.08.038. [Epub ahead of print]. |
Pax8 and Pax2 are specifically required at different steps of Xenopus pronephros development
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Citation:
Dev Biol. 2014 Nov 8. pii: S0012-1606(14)00563-6. doi: 10.1016/j.ydbio.2014.10.022. [Epub ahead of print] Epub:
Yes Abstract:
The respective role of Pax2 and Pax8 in early kidney development in vertebrates is poorly understood. In this report, we have... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Buisson I, le Bouffant R, Futel M, Riou JF, Umbhauer M. Pax8 and Pax2 are specifically required at different steps of Xenopus pronephros development. Dev Biol. 2014 Nov 8. pii: S0012-1606(14)00563-6. doi: 10.1016/j.ydbio.2014.10.022. [Epub ahead of print]. |
The transcription factor hairy/E(spl)-related 2 induces proliferation of neural progenitors and regulates neurogenesis and gliogenesis
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Citation:
Dev Biol. 2014 Nov 1. pii: S0012-1606(14)00559-4. doi: 10.1016/j.ydbio.2014.10.018. [Epub ahead of print] Epub:
Yes Abstract:
The study of molecular regulation in neural development provides information to understand how diverse neural cells are... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cheng YC, Chiang MC, Shih HY, Ma TL, Yeh TH, Huang YC, Lin CY, Lin SJ. The transcription factor hairy/E(spl)-related 2 induces proliferation of neural progenitors and regulates neurogenesis and gliogenesis. Dev Biol. 2014 Nov 1. pii: S0012-1606(14)00559-4. doi: 10.1016/j.ydbio.2014.10.018. [Epub ahead of print]. |
Non-muscle myosin IIA and IIB differentially regulate cell shape changes during zebrafish brain morphogenesis
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Citation:
Dev Biol. 2014 Oct 31. pii: S0012-1606(14)00558-2. doi: 10.1016/j.ydbio.2014.10.017. [Epub ahead of print] Epub:
Yes Abstract:
During brain morphogenesis, the neuroepithelium must fold in specific regions to delineate functional units, and give rise to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gutzman JH, Sahu SU, Kwas C. Non-muscle myosin IIA and IIB differentially regulate cell shape changes during zebrafish brain morphogenesis. Dev Biol. 2014 Oct 31. pii: S0012-1606(14)00558-2. doi: 10.1016/j.ydbio.2014.10.017. [Epub ahead of print]. |
Fezf2 promotes neuronal differentiation through localised activation of Wnt/β-catenin signalling during forebrain development
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Citation:
Development. 2014;141:4794-805. doi:10.1242/dev.115691 Epub:
Not Epub Abstract:
Brain regionalisation, neuronal subtype diversification and circuit connectivity are crucial events in the establishment of... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Zhang S, Li J, Lea R, Vleminckx K, Amaya E. Fezf2 promotes neuronal differentiation through localised activation of Wnt/β-catenin signalling during forebrain development. Development. 2014;141:4794-805. doi:10.1242/dev.115691. |
A Possible Zebrafish Model of Polycystic Kidney Disease: Knockdown of wnt5a Causes Cysts in Zebrafish Kidneys
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Citation:
J Vis Exp. 2014;94:e52156. doi:10.3791/52156 Epub:
Not Epub Abstract:
Polycystic kidney disease (PKD) is one of the most common causes of end-stage kidney disease, a devastating disease for which... Link:
Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Huang L, Xiao A, Wecker A, McBride DA, Choi SY, Zhou W, Lipschutz JH. A Possible Zebrafish Model of Polycystic Kidney Disease: Knockdown of wnt5a Causes Cysts in Zebrafish Kidneys. J Vis Exp. 2014;94:e52156. doi:10.3791/52156. |
Bi-specific splice-switching PMO oligonucleotides conjugated via a single peptide active in a mouse model of Duchenne muscular dystrophy
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Citation:
Nucl Acids Res. 2015 Jan;43(1):29-39. doi: 10.1093/nar/gku1256. Epub 2014 Dec 2 Epub:
Not Epub Abstract:
The potential for therapeutic application of splice-switching oligonucleotides (SSOs) to modulate pre-mRNA splicing is... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: mouse H2K/mdx myotubes, mice (mdx) Citation Extract: Shabanpoor F, McClorey G, Saleh AF, Järver P, Wood MJA, Gait MJ. Bi-specific splice-switching PMO oligonucleotides conjugated via a single peptide active in a mouse model of Duchenne muscular dystrophy. Nucl Acids Res. 2015 Jan;43(1):29-39. doi: 10.1093/nar/gku1256. Epub 2014 Dec 2. |
Manipulation of Developing Juvenile Structures in Purple Sea Urchins (Strongylocentrotus purpuratus) by Morpholino Injection into Late Stage Larvae
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Citation:
PLoS One. 2014 Dec 1;9(12):e113866. doi: 10.1371/journal.pone.0113866. eCollection 2014 Epub:
Not Epub Abstract:
Sea urchins have been used as experimental organisms for developmental biology for over a century. Yet, as is the case for many... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin) Citation Extract: Heyland A, Hodin J, Bishop C. Manipulation of Developing Juvenile Structures in Purple Sea Urchins (Strongylocentrotus purpuratus) by Morpholino Injection into Late Stage Larvae. PLoS One. 2014 Dec 1;9(12):e113866. doi: 10.1371/journal.pone.0113866. eCollection 2014. |
Induction of clusterin Expression by Neuronal Cell Death in Zebrafish
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Citation:
J Genet Genomics. 2014 Nov 20;41(11):583-9. doi: 10.1016/j.jgg.2014.08.007. Epub 2014 Sep 30 Epub:
Not Epub Abstract:
Clusterin, a protein associated with multiple functions, is expressed in a wide variety of mammalian tissues. Although... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jeong YM, Jin TE, Choi JH, Lee MS, Kim HT, Hwang KS, Park DS, Oh HW, Choi JK, Korzh V, Schachner M, You KH, Kim CH. Induction of clusterin Expression by Neuronal Cell Death in Zebrafish. J Genet Genomics. 2014 Nov 20;41(11):583-9. doi: 10.1016/j.jgg.2014.08.007. Epub 2014 Sep 30. |
Zebrafish Prion Protein PrP2 Controls Collective Migration Process during Lateral Line Sensory System Development
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Citation:
PLoS ONE. 2014;9(12):e113331. doi:10.1371/journal.pone.0113331 Epub:
Not Epub Abstract:
Prion protein is involved in severe neurodegenerative disorders but its physiological role is still in debate due to an absence... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Huc-Brandt S, Hieu N, Imberdis T, Cubedo N, Silhol M, Leighton PLA, Domaschke T, Allison WT, Perrier V, Rossel M. Zebrafish Prion Protein PrP2 Controls Collective Migration Process during Lateral Line Sensory System Development. PLoS ONE. 2014;9(12):e113331. doi:10.1371/journal.pone.0113331. |