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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Large-scale discovery of novel genetic causes of developmental disorders

Authors:
The Deciphering Developmental Disorders Study
Citation:
Nature. 2014 Dec 24. doi: 10.1038/nature14135. [Epub ahead of print]
Epub:
Yes
Abstract:
Despite three decades of successful, predominantly phenotype-driven discovery of the genetic causes of monogenic disorders, up...
Link:
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14135.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
The Deciphering Developmental Disorders Study. Large-scale discovery of novel genetic causes of developmental disorders. Nature. 2014 Dec 24. doi: 10.1038/nature14135. [Epub ahead of print].

Zebrafish cardiotoxicity: the effects of CYP1A inhibition and AHR2 knockdown following exposure to weak aryl hydrocarbon receptor agonists

Authors:
Brown DR, Clark BW, Garner LV, Di Giulio RT
Citation:
Environ Sci Pollut Res Int. 2014 Dec 23. [Epub ahead of print]
Epub:
Yes
Abstract:
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that mediates many of the toxic effects of...
Link:
http://link.springer.com/article/10.1007%2Fs11356-014-3969-2
Organism or Cell Type:
zebrafish
Citation Extract:
Brown DR, Clark BW, Garner LV, Di Giulio RT. Zebrafish cardiotoxicity: the effects of CYP1A inhibition and AHR2 knockdown following exposure to weak aryl hydrocarbon receptor agonists. Environ Sci Pollut Res Int. 2014 Dec 23. [Epub ahead of print].

No Evidence for AID/MBD4-Coupled DNA Demethylation in Zebrafish Embryos

Authors:
Shimoda N, Hirose K, Kaneto R, Izawa T, Yokoi H, Hashimoto N, Kikuchi Y
Citation:
PLoS ONE. 2014;9(12):e114816. doi:10.1371/journal.pone.0114816
Epub:
Not Epub
Abstract:
The mechanisms responsible for active DNA demethylation remain elusive in Metazoa. A previous study that utilized zebrafish...
Link:
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0114816
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shimoda N, Hirose K, Kaneto R, Izawa T, Yokoi H, Hashimoto N, Kikuchi Y. No Evidence for AID/MBD4-Coupled DNA Demethylation in Zebrafish Embryos. PLoS ONE. 2014;9(12):e114816. doi:10.1371/journal.pone.0114816.

High tissue glucose alters intersomitic blood vessels in zebrafish via methylglyoxal targeting the VEGF receptor signalling cascade

Authors:
Jörgens K, Stoll SJ, Pohl J, Fleming TH, Sticht C, Nawroth PP, Hammes HP, Kroll J
Citation:
Diabetes. 2014 Aug 4. pii: DB_140352. [Epub ahead of print]
Epub:
Yes
Abstract:
Hyperglycemia causes micro- and macrovascular complications in diabetic patients. Elevated glucose concentrations lead to...
Link:
http://diabetes.diabetesjournals.org/content/64/1/213.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jörgens K, Stoll SJ, Pohl J, Fleming TH, Sticht C, Nawroth PP, Hammes HP, Kroll J. High tissue glucose alters intersomitic blood vessels in zebrafish via methylglyoxal targeting the VEGF receptor signalling cascade. Diabetes. 2014 Aug 4. pii: DB_140352. [Epub ahead of print].

The Notochord Breaks Bilateral Symmetry by Controlling Cell Shapes in the Zebrafish Laterality Organ

Authors:
Compagnon J, Barone V, Rajshekar S, Kottmeier R, Pranjic-Ferscha K, Behrndt M, Heisenberg C-P
Citation:
Dev Cell. 2014;31(6):774-83. doi:10.1016/j.devcel.2014.11.003
Epub:
Not Epub
Abstract:
Kupffer’s vesicle (KV) is the zebrafish organ of laterality, patterning the embryo along its left-right (LR) axis. Regional...
Link:
http://www.cell.com/developmental-cell/abstract/S1534-5807%2814%2900720-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Compagnon J, Barone V, Rajshekar S, Kottmeier R, Pranjic-Ferscha K, Behrndt M, Heisenberg C-P. The Notochord Breaks Bilateral Symmetry by Controlling Cell Shapes in the Zebrafish Laterality Organ. Dev Cell. 2014;31(6):774-83. doi:10.1016/j.devcel.2014.11.003.

Osmotic surveillance mediates rapid wound closure through nucleotide release

Authors:
Gault WJ, Enyedi B, Niethammer P
Citation:
J Cell Biol. 2014;207:767-82. doi:10.1083/jcb.201408049
Epub:
Yes
Abstract:
Osmotic cues from the environment mediate rapid detection of epithelial breaches by leukocytes in larval zebrafish tail fins....
Link:
http://jcb.rupress.org/content/207/6/767.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gault WJ, Enyedi B, Niethammer P. Osmotic surveillance mediates rapid wound closure through nucleotide release. J Cell Biol. 2014;207:767-82. doi:10.1083/jcb.201408049 .

Xenopus Nkx6.3 Is a Neural Plate Border Specifier Required for Neural Crest Development

Authors:
Zhang Z, Shi Y, Zhao S, Li J, Li C, Mao B
Citation:
PLoS One. 2014 Dec 22;9(12):e115165. doi: 10.1371/journal.pone.0115165. eCollection 2014
Epub:
Not Epub
Abstract:
In vertebrates, the neural plate border (NPB) is established by a group of transcription factors including Dlx3, Msx1 and Zic1...
Link:
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0115165
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Zhang Z, Shi Y, Zhao S, Li J, Li C, Mao B. Xenopus Nkx6.3 Is a Neural Plate Border Specifier Required for Neural Crest Development. PLoS One. 2014 Dec 22;9(12):e115165. doi: 10.1371/journal.pone.0115165. eCollection 2014.

Modulation of p53 and met expression by krüppel-like factor 8 regulates zebrafish cerebellar development

Authors:
Tsai M, Lu Y, Liu Y, Lien H, Huang C, Wu J, Hwang SL
Citation:
Dev Neurobiol. 2014 Dec 19. doi: 10.1002/dneu.22258. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Krüppel-like factor 8 (Klf8) is a zinc-finger transcription factor implicated in cell proliferation, and cancer cell survival...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/dneu.22258/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tsai M, Lu Y, Liu Y, Lien H, Huang C, Wu J, Hwang SL. Modulation of p53 and met expression by krüppel-like factor 8 regulates zebrafish cerebellar development. Dev Neurobiol. 2014 Dec 19. doi: 10.1002/dneu.22258. [Epub ahead of print].

Tissue factor pathway inhibitor-2 is critical in zebrafish cardiogenesis

Authors:
Zhang Y, Wang H, Zhang J, Zheng F, Jiang N, Ma D
Citation:
Biochem Biophys Res Commun. 2014 Dec 11. pii: S0006-291X(14)02182-2. doi: 10.1016/j.bbrc.2014.12.017. [Epub ahead of print]
Epub:
Yes
Abstract:
Human tissue factor pathway inhibitor-2 (Tfpi-2) is an extracellular matrix-associated Kunitz-type serine proteinase inhibitor...
Link:
http://www.sciencedirect.com/science/article/pii/S0006291X14021822
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Y, Wang H, Zhang J, Zheng F, Jiang N, Ma D. Tissue factor pathway inhibitor-2 is critical in zebrafish cardiogenesis. Biochem Biophys Res Commun. 2014 Dec 11. pii: S0006-291X(14)02182-2. doi: 10.1016/j.bbrc.2014.12.017. [Epub ahead of print].

nkx2.1 and nkx2.4 genes function partially redundant during development of the zebrafish hypothalamus, preoptic region, and pallidum

Authors:
Manoli M, Driever W
Citation:
Front Neuroanat. 2014 Dec 2;8:145. doi: 10.3389/fnana.2014.00145. eCollection 2014
Epub:
Not Epub
Abstract:
During ventral forebrain development, orthologs of the homeodomain transcription factor Nkx2.1 control patterning of...
Link:
http://journal.frontiersin.org/Journal/10.3389/fnana.2014.00145/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Manoli M, Driever W. nkx2.1 and nkx2.4 genes function partially redundant during development of the zebrafish hypothalamus, preoptic region, and pallidum. Front Neuroanat. 2014 Dec 2;8:145. doi: 10.3389/fnana.2014.00145. eCollection 2014.

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