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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Phenotypic regulation of the sphingosine 1-phosphate receptor Miles Apart by GRK2

Authors:
Burczyk MS, Burkhalter MD, Blätte T, Matysik S, Caron MG, Barak LS, Philipp M
Citation:
Biochemistry. 2015;[Epub ahead of print] doi:10.1021/bi501061h
Epub:
Not Epub
Abstract:
The evolutionary conserved DRY motif at the end of the third helix of rhodopsin-like, class-A G protein-coupled receptors (...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Burczyk MS, Burkhalter MD, Blätte T, Matysik S, Caron MG, Barak LS, Philipp M. Phenotypic regulation of the sphingosine 1-phosphate receptor Miles Apart by GRK2. Biochemistry. 2015;[Epub ahead of print] doi:10.1021/bi501061h.

CD47 in the Tumor Microenvironment Limits Cooperation between Antitumor T-cell Immunity and Radiotherapy

Authors:
Soto-Pantoja DR, Terabe M, Ghosh A, Ridnour LA, DeGraff WG, Wink DA, Berzofsky JA, Roberts DD
Citation:
Cancer Res. 2014 Dec 1;74(23):6771-83. doi: 10.1158/0008-5472.CAN-14-0037-T. Epub 2014 Oct 8
Epub:
Not Epub
Abstract:
Although significant advances in radiotherapy have increased its effectiveness in many cancer settings, general strategies to...
Delivery Method:
ip injection
Organism or Cell Type:
mice
Citation Extract:
Soto-Pantoja DR, Terabe M, Ghosh A, Ridnour LA, DeGraff WG, Wink DA, Berzofsky JA, Roberts DD. CD47 in the Tumor Microenvironment Limits Cooperation between Antitumor T-cell Immunity and Radiotherapy. Cancer Res. 2014 Dec 1;74(23):6771-83. doi: 10.1158/0008-5472.CAN-14-0037-T. Epub 2014 Oct 8.

Whole-transcriptome analysis of endothelial to hematopoietic stem cell transition reveals a requirement for Gpr56 in HSC generation

Authors:
Kartalaei P, Yamada-Inagawa T, Vink CS, de Pater E, van der Linden R, Marks-Bluth J, van der Sloot A, van den Hout M, Yokomizo T, van Schaick-Solernó ML, Delwel R, Pimanda JE, van IJcken WFJ, Dzierzak E
Citation:
J Exp Med. 2014;[Epub ahead ofprint] doi:10.1084/jem.20140767
Epub:
Yes
Abstract:
Hematopoietic stem cells (HSCs) are generated via a natural transdifferentiation process known as endothelial to hematopoietic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kartalaei P, Yamada-Inagawa T, Vink CS, de Pater E, van der Linden R, Marks-Bluth J, van der Sloot A, van den Hout M, Yokomizo T, van Schaick-Solernó ML, Delwel R, Pimanda JE, van IJcken WFJ, Dzierzak E. Whole-transcriptome analysis of endothelial to hematopoietic stem cell transition reveals a requirement for Gpr56 in HSC generation. J Exp Med. 2014;[Epub ahead ofprint] doi:10.1084/jem.20140767.

A naturally occurring 4-bp deletion in the intron 4 of p53 creates a spectrum of novel p53 isoforms with anti-apoptosis function

Authors:
Shi H, Tao T, Huang D, Ou Z, Chen J, Peng J
Citation:
Nucl Acids Res. 2014;[Epub ahead of print] doi:10.1093/nar/gku1359
Epub:
Yes
Abstract:
p53 functions as a tumor suppressor by transcriptionally regulating the expression of genes involved in controlling cell...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shi H, Tao T, Huang D, Ou Z, Chen J, Peng J. A naturally occurring 4-bp deletion in the intron 4 of p53 creates a spectrum of novel p53 isoforms with anti-apoptosis function. Nucl Acids Res. 2014;[Epub ahead of print] doi:10.1093/nar/gku1359.

Nephron proximal tubule patterning and corpuscles of Stannius formation are regulated by the sim1a transcription factor and retinoic acid in zebrafish

Authors:
Cheng CN, Wingert RA
Citation:
Dev Biol. 2014 Dec 24. pii: S0012-1606(14)00650-2. doi: 10.1016/j.ydbio.2014.12.020. [Epub ahead of print]
Epub:
Yes
Abstract:
The mechanisms that establish nephron segments are poorly understood. The zebrafish embryonic kidney, or pronephros, is a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cheng CN, Wingert RA. Nephron proximal tubule patterning and corpuscles of Stannius formation are regulated by the sim1a transcription factor and retinoic acid in zebrafish. Dev Biol. 2014 Dec 24. pii: S0012-1606(14)00650-2. doi: 10.1016/j.ydbio.2014.12.020. [Epub ahead of print].

Activity-dependent expression of neuronal PAS domain-containing protein 4 (npas4a) in the developing zebrafish brain

Authors:
Klarić T, Lardelli M, Key B, Koblar S, Lewis M
Citation:
Front Neuroanat. 2014 Dec 4;8:148. doi: 10.3389/fnana.2014.00148. eCollection 2014
Epub:
Not Epub
Abstract:
In rodents, the Npas4 gene has recently been identified as being an important regulator of synaptic plasticity and memory....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Klarić T, Lardelli M, Key B, Koblar S, Lewis M. Activity-dependent expression of neuronal PAS domain-containing protein 4 (npas4a) in the developing zebrafish brain. Front Neuroanat. 2014 Dec 4;8:148. doi: 10.3389/fnana.2014.00148. eCollection 2014.

Expression and Function of Ccbe1 in the Chick Early Cardiogenic Regions Are Required for Correct Heart Development

Authors:
Furtado J, Bento M, Correia E, Inácio JM, Belo JA
Citation:
PLoS One. 2014 Dec 29;9(12):e115481. doi: 10.1371/journal.pone.0115481. eCollection 2014
Epub:
Not Epub
Abstract:
During the course of a differential screen to identify transcripts specific for chick heart/hemangioblast precursor cells, we...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Furtado J, Bento M, Correia E, Inácio JM, Belo JA. Expression and Function of Ccbe1 in the Chick Early Cardiogenic Regions Are Required for Correct Heart Development. PLoS One. 2014 Dec 29;9(12):e115481. doi: 10.1371/journal.pone.0115481. eCollection 2014.

Prioritizing causal disease genes using unbiased genomic features

Authors:
Deo RC, Musso G, Tasan M, Tang P, Poon A, Yuan C, Felix JF, Vasan RS, Beroukhim R, De Marco T, Kwok P-Y, MacRae CA, Roth FP
Citation:
Genome Biol. 2014;15:3274. doi:10.1186/s13059-014-0534-8
Epub:
Not Epub
Abstract:
Background: Cardiovascular disease (CVD) is the leading cause of death in the developed world. Human genetic studies, including...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Deo RC, Musso G, Tasan M, Tang P, Poon A, Yuan C, Felix JF, Vasan RS, Beroukhim R, De Marco T, Kwok P-Y, MacRae CA, Roth FP. Prioritizing causal disease genes using unbiased genomic features. Genome Biol. 2014;15:3274. doi:10.1186/s13059-014-0534-8.

Dietary cholesterol directly induces acute inflammasome-dependent intestinal inflammation

Authors:
Progatzky F, Sangha NJ, Yoshida N, McBrien M, Cheung J, Shia A, Scott J, Marchesi JR, Lamb JR, Bugeon L, Dallman MJ
Citation:
Nat Commun. 2014 Dec 23;5:5864. doi: 10.1038/ncomms6864
Epub:
Not Epub
Abstract:
Prolonged ingestion of a ​cholesterol- or saturated fatty acid-enriched diet induces chronic, often systemic, auto-inflammatory...
Delivery Method:
feeding
Organism or Cell Type:
zebrafish
Citation Extract:
Progatzky F, Sangha NJ, Yoshida N, McBrien M, Cheung J, Shia A, Scott J, Marchesi JR, Lamb JR, Bugeon L, Dallman MJ. Dietary cholesterol directly induces acute inflammasome-dependent intestinal inflammation. Nat Commun. 2014 Dec 23;5:5864. doi: 10.1038/ncomms6864.

Sequential actions of β-catenin and Bmp pattern the oral nerve net in Nematostella vectensis

Authors:
Watanabe H, Kuhn A, Fushiki M, Agata K, Özbek S, Fujisawa T, Holstein TW
Citation:
Nat Commun. 2014 Dec 23;5:5536. doi: 10.1038/ncomms6536
Epub:
Not Epub
Abstract:
Animal evolution is closely linked to the emergence of the nervous system. At present it is unknown how the basic mechanisms of...
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (cnidarian)
Citation Extract:
Watanabe H, Kuhn A, Fushiki M, Agata K, Özbek S, Fujisawa T, Holstein TW. Sequential actions of β-catenin and Bmp pattern the oral nerve net in Nematostella vectensis. Nat Commun. 2014 Dec 23;5:5536. doi: 10.1038/ncomms6536.

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