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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Shared regulatory programs suggest retention of blastula-stage potential in neural crest cells
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Citation:
Science. 2015 Jun 19;348(6241):1332-5. doi: 10.1126/science.aaa3655. Epub 2015 Apr 30 Epub:
Not Epub Abstract:
Neural crest cells, which are specific to vertebrates, arise in the ectoderm but can generate cell types that are typically... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Buitrago-Delgado E, Nordin K, Rao A, Geary L, LaBonne C. Shared regulatory programs suggest retention of blastula-stage potential in neural crest cells. Science. 2015 Jun 19;348(6241):1332-5. doi: 10.1126/science.aaa3655. Epub 2015 Apr 30. |
Zic1 controls placode progenitor formation non-cell autonomously by regulating retinoic acid production and transport
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Citation:
Nat Comm. 2015;6:7476. doi:10.1038/ncomms8476 Epub:
Not Epub Abstract:
All cranial placode progenitors arise from a common precursor field anterior to the neural plate, the pre-placodal region (PPR... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Jaurena MB, Juraver-Geslin H, Devotta A, Saint-Jeannet J-P. Zic1 controls placode progenitor formation non-cell autonomously by regulating retinoic acid production and transport. Nat Comm. 2015;6:7476. doi:10.1038/ncomms8476. |
Dendritic Nanoconjugates for Intracellular Delivery of Neutral Oligonucleotides
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Citation:
Nanoscale. 2015;[Epub ahead of print] doi:10.1039/C5NR01665G Epub:
Yes Abstract:
Dendrimer-based gene delivery has been constrained by intrinsic toxicity and suboptimal nanostructure. Conjugation of neutral... Delivery Method:
PAMAM-linked Organism or Cell Type:
cell culture: cancer cells Citation Extract: Ming X, Wu L, Carver K, Yuan A, Min Y. Dendritic Nanoconjugates for Intracellular Delivery of Neutral Oligonucleotides. Nanoscale. 2015;[Epub ahead of print] doi:10.1039/C5NR01665G. |
Zdhhc15b Regulates Differentiation of Diencephalic Dopaminergic Neurons in Zebrafish
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Citation:
J Cell Biochem. 2015 Jun 11. doi: 10.1002/jcb.25256. [Epub ahead of print] Epub:
Yes Abstract:
The aspartate-histidine-histidine-cysteine (DHHC) protein family shares a 50-amino acid cysteine-rich domain with a conserved... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang F, Chen X, Shi W, Yao L, Gao M, Yang Y, Hao A. Zdhhc15b Regulates Differentiation of Diencephalic Dopaminergic Neurons in Zebrafish. J Cell Biochem. 2015 Jun 11. doi: 10.1002/jcb.25256. [Epub ahead of print]. |
Ca2+ enrichment in culture medium potentiates effect of oligonucleotides
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Citation:
Nucl Acids Res. 2015;[Epub ahead of print] doi:10.1093/nar/gkv626 Epub:
Yes Abstract:
Antisense and RNAi-related oligonucleotides have gained attention as laboratory tools and therapeutic agents based on their... Delivery Method:
CaCl2, Endo-Porter Organism or Cell Type:
cell culture: Huh-7 cells Citation Extract: Hori S-i, Yamamoto T, Waki R, Wada S, Wada F, Noda M, Obika S. Ca2+ enrichment in culture medium potentiates effect of oligonucleotides. Nucl Acids Res. 2015;[Epub ahead of print] doi:10.1093/nar/gkv626. |
The use of urinary and kidney SILAM proteomics to monitor kidney response to high dose morpholino oligonucleotides in the mdx mouse
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Citation:
Tox Rep. 2015;2:838-49. doi:10.1016/j.toxrep.2015.05.008 Epub:
Not Epub Abstract:
Phosphorodiamidate morpholino oligonucleotides (PMO) are used as a promising exon-skipping gene therapy for Duchenne muscular... Delivery Method:
injection Organism or Cell Type:
mice, mdx Citation Extract: Zhang A, Uaesoontrachoon K, Shaughnessy C, Das JR, Rayavarapu S, Brown KJ, Ray PE, Nagaraju K, van den Anker JN, Hoffman EP, Hathout Y. The use of urinary and kidney SILAM proteomics to monitor kidney response to high dose morpholino oligonucleotides in the mdx mouse. Tox Rep. 2015;2:838-49. doi:10.1016/j.toxrep.2015.05.008. |
miR-181a/b control the assembly of visual circuitry by regulating retinal axon specification and growth
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Citation:
Dev Neurobiol. 2015 Feb 27. doi: 10.1002/dneu.22282. [Epub ahead of print] Epub:
Yes Abstract:
Connectivity and function of neuronal circuitry require the correct specification and growth of axons and dendrites. Here we... Delivery Method:
microinjection Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Carrella S, D'Agostino Y, Barbato S, Huber-Reggi SP, Salierno FG, Manfredi A, Neuhauss SC, Banfi S, Conte I. miR-181a/b control the assembly of visual circuitry by regulating retinal axon specification and growth. Dev Neurobiol. 2015 Feb 27. doi: 10.1002/dneu.22282. [Epub ahead of print]. |
Cross-Scale Integrin Regulation Organizes ECM and Tissue Topology
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Citation:
Dev Cell. 2015;[Epub ahead of print] doi:10.1016/j.devcel.2015.05.005 Epub:
Yes Abstract:
The diverse morphologies of animal tissues are underlain by different configurations of adherent cells and extracellular matrix... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jülich D, Cobb G, Melo AM, McMillen P, Lawton AK, Mochrie SGJ, Rhoades E, Holley SA. Cross-Scale Integrin Regulation Organizes ECM and Tissue Topology. Dev Cell. 2015;[Epub ahead of print] doi:10.1016/j.devcel.2015.05.005. |
The chromatin remodeler chd5 is necessary for proper head development during embryogenesis of Danio rerio
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Citation:
Biochim Biophys Acta. 2015 Jun 16. pii: S1874-9399(15)00129-7. doi: 10.1016/j.bbagrm.2015.06.006. [Epub ahead of print] Epub:
Yes Abstract:
The chromatin remodeler CHD5 plays a critical role in tumor suppression and neurogenesis in mammals. CHD5 contributes to gene... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bishop B, Ho KK, Tyler K, Smith A, Bonilla S, Leung YF, Ogas J. The chromatin remodeler chd5 is necessary for proper head development during embryogenesis of Danio rerio. Biochim Biophys Acta. 2015 Jun 16. pii: S1874-9399(15)00129-7. doi: 10.1016/j.bbagrm.2015.06.006. [Epub ahead of print]. |
Human Kidney Disease-causing INF2 Mutations Perturb Rho/Dia Signaling in the Glomerulus
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Citation:
EBioMedicine. 2014 Nov 13;1(2-3):107-15. doi: 10.1016/j.ebiom.2014.11.009. eCollection 2014 Dec Epub:
Not Epub Abstract:
Mutations in Inverted Formin 2 (INF2), a diaphanous formin family protein that regulates actin cytoskeleton dynamics, cause... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sun H, Al-Romaih KI, MacRae CA, Pollak MR. Human Kidney Disease-causing INF2 Mutations Perturb Rho/Dia Signaling in the Glomerulus. EBioMedicine. 2014 Nov 13;1(2-3):107-15. doi: 10.1016/j.ebiom.2014.11.009. eCollection 2014 Dec. |