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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination

Authors:
Wei L, Nakajima S, Böhm S, Bernstein KA, Shen Z, Tsang M, Levine AS, Lan L
Citation:
PNAS. 2015;112(27):E3495-E3504. doi:10.1073/pnas.1507105112
Epub:
Not Epub
Abstract:
Damage repair mechanisms at transcriptionally active sites during the G0/G1 phase are largely unknown. To elucidate these...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wei L, Nakajima S, Böhm S, Bernstein KA, Shen Z, Tsang M, Levine AS, Lan L. DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination. PNAS. 2015;112(27):E3495-E3504. doi:10.1073/pnas.1507105112.

In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress

Authors:
Anderson BR, Howell DN, Soldano K, Garrett ME, Katsanis N, Telen MJ, Davis EE, Ashley-Koch AE
Citation:
PLoS Genet. 2015;11(7):e1005349. doi:10.1371/journal.pgen.1005349
Epub:
Not Epub
Abstract:
African Americans have a disproportionate risk for developing nephropathy. This disparity has been attributed to coding...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Anderson BR, Howell DN, Soldano K, Garrett ME, Katsanis N, Telen MJ, Davis EE, Ashley-Koch AE. In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress. PLoS Genet. 2015;11(7):e1005349. doi:10.1371/journal.pgen.1005349.

Plastin 3 Expression Does Not Modify Spinal Muscular Atrophy Severity in the ∆7 SMA Mouse

Authors:
McGovern VL, Massoni-Laporte A, Wang X, Le TT, Le HT, Beattie CE, Rich MM, Burghes AH
Citation:
PLoS One. 2015 Jul 2;10(7):e0132364. doi: 10.1371/journal.pone.0132364. eCollection 2015
Epub:
Not Epub
Abstract:
Spinal muscular atrophy is caused by loss of the SMN1 gene and retention of SMN2. The SMN2 copy number inversely correlates...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
McGovern VL, Massoni-Laporte A, Wang X, Le TT, Le HT, Beattie CE, Rich MM, Burghes AH. Plastin 3 Expression Does Not Modify Spinal Muscular Atrophy Severity in the ∆7 SMA Mouse. PLoS One. 2015 Jul 2;10(7):e0132364. doi: 10.1371/journal.pone.0132364. eCollection 2015.

Zebrafish Wnt9b Patterns the First Pharyngeal Arch into D-I-V Domains and Promotes Anterior-Medial Outgrowth

Authors:
Jackson HW, Prakash D, Litaker M, Ferreira T, Jezewski PA
Citation:
Am J Molec Biol. 2015;5(3):[Epub] doi:10.4236/ajmb.2015.53006
Epub:
Yes
Abstract:
Disrupted morphogenesis and growth of the embryonic maxillary jaw leads to oral facial clefting in humans (OFC) and results in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jackson HW, Prakash D, Litaker M, Ferreira T, Jezewski PA. Zebrafish Wnt9b Patterns the First Pharyngeal Arch into D-I-V Domains and Promotes Anterior-Medial Outgrowth. Am J Molec Biol. 2015;5(3):[Epub] doi:10.4236/ajmb.2015.53006.

Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction

Authors:
Jia XE, Ma K, Xu T, Gao L, Wu S, Fu C, Zhang W, Wang Z, Liu K, Dong M, Jing C, Ren C, Dong Z, Chen Y, Jin Y, Huang Q, Chang X, Deng M, Li L, Luo L, Zhu J, Dang Y, Chang HC, Zon LI, Zhou Y, Chen S, Pan W
Citation:
Cell Res. 2015 Jul 3. doi: 10.1038/cr.2015.81. [Epub ahead of print]
Epub:
Yes
Abstract:
Dysregulation of ribosome biogenesis causes human diseases, such as Diamond-Blackfan anemia, del (5q-) syndrome and bone marrow...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jia XE, Ma K, Xu T, Gao L, Wu S, Fu C, Zhang W, Wang Z, Liu K, Dong M, Jing C, Ren C, Dong Z, Chen Y, Jin Y, Huang Q, Chang X, Deng M, Li L, Luo L, Zhu J, Dang Y, Chang HC, Zon LI, Zhou Y, Chen S, Pan W. Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction. Cell Res. 2015 Jul 3. doi: 10.1038/cr.2015.81. [Epub ahead of print].

Lack of phosphomannomutase 2 affects Xenopus laevis morphogenesis and the non-canonical Wnt5a/Ror2 signalling

Authors:
Himmelreich N, Kaufmann LT, Steinbeisser H, Körner C, Thiel C
Citation:
J Inherit Metab Dis. 2015 Jul 4. [Epub ahead of print]
Epub:
Yes
Abstract:
Reduced phosphomannomutase 2 activity in man leads to hypoglycosylation of glycoconjugates causing PMM2-CDG, the most common...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Himmelreich N, Kaufmann LT, Steinbeisser H, Körner C, Thiel C. Lack of phosphomannomutase 2 affects Xenopus laevis morphogenesis and the non-canonical Wnt5a/Ror2 signalling. J Inherit Metab Dis. 2015 Jul 4. [Epub ahead of print].

Ribosomal Protein Mutations Result in Constitutive p53 Protein Degradation through Impairment of the AKT Pathway

Authors:
Antunes AT, Goos YJ, Pereboom TC, Hermkens D, Wlodarski MW, Da Costa L, MacInnes AW
Citation:
PLoS Genet. 2015;11(7):e1005326. doi:10.1371/journal.pgen.1005326
Epub:
Not Epub
Abstract:
Mutations in ribosomal protein (RP) genes can result in the loss of erythrocyte progenitor cells and cause severe anemia. This...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Antunes AT, Goos YJ, Pereboom TC, Hermkens D, Wlodarski MW, Da Costa L, MacInnes AW. Ribosomal Protein Mutations Result in Constitutive p53 Protein Degradation through Impairment of the AKT Pathway. PLoS Genet. 2015;11(7):e1005326. doi:10.1371/journal.pgen.1005326.

TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis

Authors:
Gao L, Li D, Ma K, Zhang W, Xu T, Fu C, Jing C, Jia X, Wu S, Sun X, Dong M, Deng M, Chen Y, Shu W, Penf J, Wan F, Zhou Y, Zon LI, Pan W
Citation:
PLoS Genet. 2015;11(7): e1005346. doi:10.1371/journal.pgen.1005346
Epub:
Not Epub
Abstract:
In vertebrate definitive hematopoiesis, nascent hematopoietic stem/progenitor cells (HSPCs) migrate to and reside in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gao L, Li D, Ma K, Zhang W, Xu T, Fu C, Jing C, Jia X, Wu S, Sun X, Dong M, Deng M, Chen Y, Shu W, Penf J, Wan F, Zhou Y, Zon LI, Pan W. TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis. PLoS Genet. 2015;11(7): e1005346. doi:10.1371/journal.pgen.1005346.

RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells

Authors:
Hoeppner LH, Sinha S, Wang Y, Bhattacharya R, Dutta S, Gong X, Bedell VM, Suresh S, Chun CZ, Ramchandran R, Ekker SC, Mukhopadhyay D
Citation:
J Cell Sci. 2015;[Epub ahead of print] doi:10.1242/jcs.167601
Epub:
Yes
Abstract:
Vasculogenesis and angiogenesis are controlled by vascular permeability factor/vascular endothelial growth factor A (VEGF)....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish keratocytes
Citation Extract:
Hoeppner LH, Sinha S, Wang Y, Bhattacharya R, Dutta S, Gong X, Bedell VM, Suresh S, Chun CZ, Ramchandran R, Ekker SC, Mukhopadhyay D. RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells. J Cell Sci. 2015;[Epub ahead of print] doi:10.1242/jcs.167601 .

Tinkering signaling pathways by gain and loss of protein isoforms: the case of the EDA pathway regulator EDARADD

Authors:
Sadier A, Lambert E, Chevret P, Décimo D, Sémon M, Tohmé M, Ruggiero F, Ohlmann T, Pantalacci S, Laudet V
Citation:
BMC Evol Bio. 2015;15:129 doi:10.1186/s12862-015-0395-0
Epub:
Not Epub
Abstract:
Background: Only a handful of signaling pathways are major actors of development and responsible for both the conservation and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sadier A, Lambert E, Chevret P, Décimo D, Sémon M, Tohmé M, Ruggiero F, Ohlmann T, Pantalacci S, Laudet V. Tinkering signaling pathways by gain and loss of protein isoforms: the case of the EDA pathway regulator EDARADD. BMC Evol Bio. 2015;15:129 doi:10.1186/s12862-015-0395-0.

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