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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Common and specific downstream signaling targets controlled by Tlr2 and Tlr5 innate immune signaling in zebrafish
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Citation:
BMC Genomics. 2015;16:547 doi:10.1186/s12864-015-1740-9 Epub:
Not Epub Abstract:
Background: Although the responses to many pathogen associated molecular patterns (PAMPs) in cell cultures and extracted organs... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang S, Marín-Juez R, Meijer AH, Spaink HP. Common and specific downstream signaling targets controlled by Tlr2 and Tlr5 innate immune signaling in zebrafish. BMC Genomics. 2015;16:547 doi:10.1186/s12864-015-1740-9. |
In Vitro Assays to Assess Exon Skipping in Duchenne Muscular Dystrophy
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Citation:
Methods Mol Biol. 2015;1324:317-29. doi: 10.1007/978-1-4939-2806-4_20 Epub:
Not Epub Abstract:
Cell-penetrating peptide (CPP)-mediated delivery of phosphorodiamidate morpholino oligomers (PMO) results in efficient exon... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: skeletal H2k cells and primary cardiomyocytes from mdx mice Citation Extract: Boisguerin P, O'Donovan L, Gait MJ, Lebleu B. In Vitro Assays to Assess Exon Skipping in Duchenne Muscular Dystrophy. Methods Mol Biol. 2015;1324:317-29. doi: 10.1007/978-1-4939-2806-4_20. |
Splicing inhibition decreases phosphorylation level of Ser2 in Pol II CTD
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Citation:
Nucl Acids Res. 2015;[Epub ahead of print] doi:10.1093/nar/gkv740 Epub:
Yes Abstract:
Phosphorylation of the C-terminal domain of the largest subunit of RNA polymerase II (Pol II), especially Ser2 and Ser5... Delivery Method:
electroporation Organism or Cell Type:
cell culture: HeLa Citation Extract: Koga M, Hayashi M, Kaida D. Splicing inhibition decreases phosphorylation level of Ser2 in Pol II CTD. Nucl Acids Res. 2015;[Epub ahead of print] doi:10.1093/nar/gkv740. |
AVI-7288 for Marburg Virus in Nonhuman Primates and Humans
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Citation:
New Engl J Med. 2015;373:339-48. doi:10.1056/NEJMoa1410345 Epub:
Not Epub Abstract:
Background: AVI-7288 is a phosphorodiamidate morpholino oligomer with positive charges that targets the viral messenger RNA... Delivery Method:
infusion Organism or Cell Type:
Humans and nonhuman primates Citation Extract: Heald AE, Charleston JS, Iversen PL, Warren TK, Saoud JB, Al-Ibrahim M, Wells JW, Warfield KL, Swenson DL, Welch LS, Sazani P, Wong M, Berry D, Kaye EM, Bavari S. AVI-7288 for Marburg Virus in Nonhuman Primates and Humans. New Engl J Med. 2015;373:339-48. doi:10.1056/NEJMoa1410345. |
Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment
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Citation:
Nature. 2015;523:468-71. doi:10.1038/nature14569 Epub:
Not Epub Abstract:
Haematopoietic stem and progenitor cell (HSPC) transplant is a widely used treatment for life-threatening conditions such as... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li P, Lahvic JL, Binder V, Pugach EK, Riley EB, Tamplin OJ, Panigrahy D, Bowman TV, Barrett FG, Heffner GC, McKinney-Freeman S, Schlaeger TM, Daley GQ, Zeldin DC, Zon LI. Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. Nature. 2015;523:468-71. doi:10.1038/nature14569. |
von Hippel-Lindau gene plays a role during zebrafish pronephros development
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Citation:
In Vitro Cell Dev Biol Anim. 2015 Jul 21. [Epub ahead of print] Epub:
Yes Abstract:
von Hippel-Lindau (pVHL)-mediated ubiquitination of HIF-1α plays a central role in the cellular responses to changes in oxygen... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen YH, Chang CF, Lai YY, Sun CY, Ding YJ, Tsai JN. von Hippel-Lindau gene plays a role during zebrafish pronephros development. In Vitro Cell Dev Biol Anim. 2015 Jul 21. [Epub ahead of print]. |
Pannexin 3 is required for normal progression of skeletal development in vertebrates
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Citation:
FASEB J. 2015 Jul 16. pii: fj.15-273722. [Epub ahead of print] Epub:
Yes Abstract:
The vertebrate skeletal system has various functions, including support, movement, protection, and the production of blood... Organism or Cell Type:
zebrafish Citation Extract: Oh SK, Shin JO, Baek JI, Lee J, Bae JW, Ankamerddy H, Kim MJ, Huh TL, Ryoo ZY, Kim UK, Bok J, Lee KY. Pannexin 3 is required for normal progression of skeletal development in vertebrates. FASEB J. 2015 Jul 16. pii: fj.15-273722. [Epub ahead of print]. |
Annexin A3 Regulates Early Blood Vessel Formation
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Citation:
PLoS ONE. 2015;10(7):e0132580. doi:10.1371/journal.pone.0132580 Epub:
Not Epub Abstract:
Annexins are a large family of calcium binding proteins that associate with cell membrane phospholipids and are involved in... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Meadows SM, Cleaver O. Annexin A3 Regulates Early Blood Vessel Formation. PLoS ONE. 2015;10(7):e0132580. doi:10.1371/journal.pone.0132580. |
Missense mutations in TENM4, a regulator of axon guidance and central myelination, cause essential tremor
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Citation:
Hum Mol Genet. 2015;[Epub ahead of print] doi: 10.1093/hmg/ddv281 Epub:
Yes Abstract:
Essential tremor (ET) is a common movement disorder with an estimated prevalence of 5% of the population aged over 65 years. In... Organism or Cell Type:
zebrafish Citation Extract: Hor H, Francescatto L, Bartesaghi L, Ortega-Cubero S, Kousi M, Lorenzo-Betancor O, Jiménez-Jiménez FJ, Gironell A, Clarimón J, Drechsel O, Agúndez JAG, Kenzelmann Broz D, Chiquet-Ehrismann R, Lleó A, Coria F, García-Martin E, Alonso-Navarro H, Martí MJ, Kulisevsky J, Hor CN, Ossowski S, Chrast R, Katsanis N, Pastor P, Estivill X. Missense mutations in TENM4, a regulator of axon guidance and central myelination, cause essential tremor. Hum Mol Genet. 2015;[Epub ahead of print] doi: 10.1093/hmg/ddv281. |
Zebrafish TARP Cacng2 is required for the expression and normal development of AMPA receptors at excitatory synapses
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Citation:
Dev Neurobiol. 2015 Jul 16. doi: 10.1002/dneu.22327. [Epub ahead of print] Epub:
Yes Abstract:
Fast excitatory synaptic transmission in the CNS is mediated by the neurotransmitter glutamate, binding to and activating AMPA... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Roy B, Ahmed KT, Cunningham ME, Ferdous J, Mukherjee R, Zeng W, Chen XZ, Ali DW. Zebrafish TARP Cacng2 is required for the expression and normal development of AMPA receptors at excitatory synapses. Dev Neurobiol. 2015 Jul 16. doi: 10.1002/dneu.22327. [Epub ahead of print]. |