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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

The Wnt receptor Frizzled-4 modulates ADAM13 metalloprotease activity

Authors:
Abbruzzese G, Gorny AK, Kaufmann LT, Cousin H, Kleino I, Steinbeisser H, Alfandari D
Citation:
J Cell Sci. 2015 Mar 15;128(6):1139-49. doi: 10.1242/jcs.163063. Epub 2015 Jan 22
Epub:
Not Epub
Abstract:
Cranial neural crest (CNC) cells are a transient population of stem cells that originate at the border of the neural plate and...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Abbruzzese G, Gorny AK, Kaufmann LT, Cousin H, Kleino I, Steinbeisser H, Alfandari D. The Wnt receptor Frizzled-4 modulates ADAM13 metalloprotease activity. J Cell Sci. 2015 Mar 15;128(6):1139-49. doi: 10.1242/jcs.163063. Epub 2015 Jan 22.

Quantitative optical coherence tomography imaging of intermediate flow defect phenotypes in ciliary physiology and pathophysiology

Authors:
Huang BK, Gamm UA, Jonas S, Khokha MK, Choma MA
Citation:
J Biomed Opt. 2015 Mar;20(3):030502. doi: 10.1117/1.JBO.20.3.030502
Epub:
Not Epub
Abstract:
Cilia-driven fluid flow is a critical yet poorly understood aspect of pulmonary physiology. Here, we demonstrate that optical...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis, zebrafish
Citation Extract:
Huang BK, Gamm UA, Jonas S, Khokha MK, Choma MA. Quantitative optical coherence tomography imaging of intermediate flow defect phenotypes in ciliary physiology and pathophysiology. J Biomed Opt. 2015 Mar;20(3):030502. doi: 10.1117/1.JBO.20.3.030502.

β-Amyloid precursor protein-b is essential for Mauthner cell development in the zebrafish in a Notch-dependent manner

Authors:
Banote RK, Edling M, Eliassen F, Kettunen P, Zetterberg H, Abramsson A
Citation:
Dev Biol. 2016;[Epub ahead of print] doi:10.1016/j.ydbio.2016.03.012
Epub:
Yes
Abstract:
Amyloid precursor protein (APP) is a transmembrane glycoprotein that has been the subject of intense research because of its...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Banote RK, Edling M, Eliassen F, Kettunen P, Zetterberg H, Abramsson A. β-Amyloid precursor protein-b is essential for Mauthner cell development in the zebrafish in a Notch-dependent manner. Dev Biol. 2016;[Epub ahead of print] doi:10.1016/j.ydbio.2016.03.012.

Identifying candidate genes for 2p15p16.1 microdeletion syndrome using clinical, genomic, and functional analysis

Authors:
Bagheri H, Badduke C, Qiao Y, Colnaghi R, Abramowicz I, Alcantara D, Dunham C, Wen J, Wildin RS, Nowaczyk MJM, Eichmeyer J, Lehman A, Maranda B, Martell S, Shan X, Lewis SME, O’Driscoll M, Gregory-Evans CY, Rajcan-Separovic E
Citation:
JCI Insight. 2016;1(3):e85461. doi:10.1172/jci.insight.85461
Epub:
Not Epub
Abstract:
The 2p15p16.1 microdeletion syndrome has a core phenotype consisting of intellectual disability, microcephaly, hypotonia,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bagheri H, Badduke C, Qiao Y, Colnaghi R, Abramowicz I, Alcantara D, Dunham C, Wen J, Wildin RS, Nowaczyk MJM, Eichmeyer J, Lehman A, Maranda B, Martell S, Shan X, Lewis SME, O’Driscoll M, Gregory-Evans CY, Rajcan-Separovic E. Identifying candidate genes for 2p15p16.1 microdeletion syndrome using clinical, genomic, and functional analysis. JCI Insight. 2016;1(3):e85461. doi:10.1172/jci.insight.85461.

Evolution of gene regulatory network topology and dorsal-1 ventral axis specification in early development of sea urchins (Echinoidea)

Authors:
Erkenbrack EM
Citation:
bioRxiv. 2016. doi:10.1101/044149
Epub:
Yes
Abstract:
Developmental gene regulatory networks (dGRNs) are assemblages of interacting regulatory factors that direct ontogeny of animal...
Delivery Method:
microinjection
Organism or Cell Type:
Eucidaris tribuloides (sea urchin)
Citation Extract:
Erkenbrack EM. Evolution of gene regulatory network topology and dorsal-1 ventral axis specification in early development of sea urchins (Echinoidea). bioRxiv. 2016. doi:10.1101/044149.

Sonic hedgehog is a chemotactic neural crest cell guide that is perturbed by ethanol exposure

Authors:
Tolosa EJ, Fernández-Zapico ME, Battiato NL, Rovasio RA
Citation:
Eur J Cell Biol. 2016 Feb 20. pii: S0171-9335(16)30006-1. doi: 10.1016/j.ejcb.2016.02.003. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Our aim was to understand the involvement of Sonic hedgehog (Shh) morphogen in the oriented distribution of neural crest cells...
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Tolosa EJ, Fernández-Zapico ME, Battiato NL, Rovasio RA. Sonic hedgehog is a chemotactic neural crest cell guide that is perturbed by ethanol exposure. Eur J Cell Biol. 2016 Feb 20. pii: S0171-9335(16)30006-1. doi: 10.1016/j.ejcb.2016.02.003. [Epub ahead of print].

Cross-species functional analyses reveal shared and separate roles for Sox11 in frog primary neurogenesis and mouse cortical neuronal differentiation

Authors:
Chen C, Jin J, Lee GA, Silva E, Donoghue M
Citation:
Biol Open. 2016 Mar 9. pii: bio.015404. doi: 10.1242/bio.015404. [Epub ahead of print]
Epub:
Yes
Abstract:
A well-functioning brain requires production of the correct number and types of cells during development; cascades of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chen C, Jin J, Lee GA, Silva E, Donoghue M. Cross-species functional analyses reveal shared and separate roles for Sox11 in frog primary neurogenesis and mouse cortical neuronal differentiation. Biol Open. 2016 Mar 9. pii: bio.015404. doi: 10.1242/bio.015404. [Epub ahead of print].

vox homeobox gene: a novel regulator of midbrain-hindbrain boundary development in medaka fish?

Authors:
Fabian P, Pantzartzi CN, Kozmikova I, Kozmik Z
Citation:
Dev Genes Evol. 2016 Mar 10. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The midbrain-hindbrain boundary (MHB) is one of the key organizing centers of the vertebrate central nervous system (CNS). Its...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Fabian P, Pantzartzi CN, Kozmikova I, Kozmik Z. vox homeobox gene: a novel regulator of midbrain-hindbrain boundary development in medaka fish?. Dev Genes Evol. 2016 Mar 10. [Epub ahead of print].

Noggin4 is a long-range inhibitor of Wnt8 signalling that regulates head development in Xenopus laevis

Authors:
Eroshkin FM, Nesterenko AM, Borodulin AV, Martynova NY, Ermakova GV, Gyoeva FK, Orlov EE, Belogurov AA, Lukyanov KA, Bayramov AV, Zaraisky AG
Citation:
Sci Rep. 2016;6:23049. doi:10.1038/srep23049
Epub:
Not Epub
Abstract:
Noggin4 is a Noggin family secreted protein whose molecular and physiological functions remain unknown. In this study, we...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Eroshkin FM, Nesterenko AM, Borodulin AV, Martynova NY, Ermakova GV, Gyoeva FK, Orlov EE, Belogurov AA, Lukyanov KA, Bayramov AV, Zaraisky AG. Noggin4 is a long-range inhibitor of Wnt8 signalling that regulates head development in Xenopus laevis. Sci Rep. 2016;6:23049. doi:10.1038/srep23049.

Prp40 pre-mRNA processing factor 40 homolog B (PRPF40B) associates with SF1 and U2AF65 and modulates alternative pre-mRNA splicing in vivo

Authors:
Becerra S, Montes M, Hernández-Munain C, Suñé C
Citation:
RNA. 2015 Mar;21(3):438-57. doi: 10.1261/rna.047258.114. Epub 2015 Jan 20
Epub:
Not Epub
Abstract:
The first stable complex formed during the assembly of spliceosomes onto pre-mRNA substrates in mammals includes U1 snRNP,...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HEK293T
Citation Extract:
Becerra S, Montes M, Hernández-Munain C, Suñé C. Prp40 pre-mRNA processing factor 40 homolog B (PRPF40B) associates with SF1 and U2AF65 and modulates alternative pre-mRNA splicing in vivo. RNA. 2015 Mar;21(3):438-57. doi: 10.1261/rna.047258.114. Epub 2015 Jan 20.

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