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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
p53 isoform Δ113p53/Δ133p53 promotes DNA double-strand break repair to protect cell from death and senescence in response to DNA damage
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Citation:
Cell Res. 2015 Mar;25(3):351-69. doi: 10.1038/cr.2015.22. Epub 2015 Feb 20 Epub:
Not Epub Abstract:
The inhibitory role of p53 in DNA double-strand break (DSB) repair seems contradictory to its tumor-suppressing property. The... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gong L, Gong H, Pan X, Chang C, Ou Z, Ye S, Yin L, Yang L, Tao T, Zhang Z, Liu C, Lane DP, Peng J, Chen J. p53 isoform Δ113p53/Δ133p53 promotes DNA double-strand break repair to protect cell from death and senescence in response to DNA damage. Cell Res. 2015 Mar;25(3):351-69. doi: 10.1038/cr.2015.22. Epub 2015 Feb 20. |
Molecular association between beta-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/beta-catenin signaling
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Citation:
Oncogene. 2008 Oct 2;27(44):5845-55. doi: 10.1038/onc.2008.202. Epub 2008 Jul 21 Epub:
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The canonical Wnt/beta-catenin pathway is a highly conserved signaling cascade that is involved in development and stem cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Upadhyay G, Goessling W, North TE, Xavier R, Zon LI, Yajnik V. Molecular association between beta-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/beta-catenin signaling. Oncogene. 2008 Oct 2;27(44):5845-55. doi: 10.1038/onc.2008.202. Epub 2008 Jul 21. |
Intraciliary calcium oscillations initiate vertebrate left-right asymmetry
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Citation:
Curr Biol. 2015 Mar 2;25(5):556-67. doi: 10.1016/j.cub.2014.12.051. Epub 2015 Feb 5 Epub:
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BACKGROUND: Bilateral symmetry during vertebrate development is broken at the left-right organizer (LRO) by ciliary motility... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yuan S, Zhao L, Brueckner M, Sun Z. Intraciliary calcium oscillations initiate vertebrate left-right asymmetry. Curr Biol. 2015 Mar 2;25(5):556-67. doi: 10.1016/j.cub.2014.12.051. Epub 2015 Feb 5. |
A novel role for Ascl1 in the regulation of mesendoderm formation via HDAC-dependent antagonism of VegT
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Citation:
Development. 2016 Feb 1;143(3):492-503. doi: 10.1242/dev.126292. Epub 2015 Dec 23 Epub:
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Maternally expressed proteins function in vertebrates to establish the major body axes of the embryo and to establish a pre-... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Gao L, Zhu X, Chen G, Ma X, Zhang Y, Khand AA, Shi H, Gu F, Lin H, Chen Y, Zhang H, He L, Tao Q. A novel role for Ascl1 in the regulation of mesendoderm formation via HDAC-dependent antagonism of VegT. Development. 2016 Feb 1;143(3):492-503. doi: 10.1242/dev.126292. Epub 2015 Dec 23. |
Cannabinoid Receptor-2 Regulates Embryonic Hematopoietic Stem Cell Development via Prostaglandin E2 and P-Selectin Activity
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Citation:
Stem Cells. 2015 Aug;33(8):2596-612. doi: 10.1002/stem.2044. Epub 2015 May 26 Epub:
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Cannabinoids (CB) modulate adult hematopoietic stem and progenitor cell (HSPCs) function, however, impact on the production,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Esain V, Kwan W, Carroll KJ, Cortes M, Liu SY, Frechette GM, Sheward LM, Nissim S, Goessling W, North TE. Cannabinoid Receptor-2 Regulates Embryonic Hematopoietic Stem Cell Development via Prostaglandin E2 and P-Selectin Activity. Stem Cells. 2015 Aug;33(8):2596-612. doi: 10.1002/stem.2044. Epub 2015 May 26. |
Opposing Nodal/Vg1 and BMP signals mediate axial patterning in embryos of the basal chordate amphioxus
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Citation:
Dev Biol. 2010 Aug 1;344(1):377-89. doi: 10.1016/j.ydbio.2010.05.016. Epub 2010 May 19. Erratum in: Dev Biol. 2011 Apr 1;352(1):179 Epub:
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The basal chordate amphioxus resembles vertebrates in having a dorsal, hollow nerve cord, a notochord and somites. However, it... Delivery Method:
microinjection Organism or Cell Type:
Branchiostoma floridae (amphioxis) Citation Extract: Onai T, Yu JK, Blitz IL, Cho KW, Holland LZ. Opposing Nodal/Vg1 and BMP signals mediate axial patterning in embryos of the basal chordate amphioxus. Dev Biol. 2010 Aug 1;344(1):377-89. doi: 10.1016/j.ydbio.2010.05.016. Epub 2010 May 19. Erratum in: Dev Biol. 2011 Apr 1;352(1):179. |
Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling
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Citation:
Sci Signal. 2009 May 26;2(72):ra25. doi: 10.1126/scisignal.2000230 Epub:
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Wnts are secreted ligands that activate several receptor-mediated signal transduction cascades. Homeostatic Wnt signaling... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: James RG, Biechele TL, Conrad WH, Camp ND, Fass DM, Major MB, Sommer K, Yi X, Roberts BS, Cleary MA, Arthur WT, MacCoss M, Rawlings DJ, Haggarty SJ, Moon RT
. Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling. Sci Signal. 2009 May 26;2(72):ra25. doi: 10.1126/scisignal.2000230. |
Atrogin-1 Deficiency Leads to Myopathy and Heart Failure in Zebrafish
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Citation:
Int J Mol Sci. 2016 Jan 30;17(2). pii: E187. doi: 10.3390/ijms17020187 Epub:
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Orchestrated protein synthesis and degradation is fundamental for proper cell function. In muscle, impairment of proteostasis... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bühler A, Kustermann M, Bummer T, Rottbauer W, Sandri M, Just S. Atrogin-1 Deficiency Leads to Myopathy and Heart Failure in Zebrafish. Int J Mol Sci. 2016 Jan 30;17(2). pii: E187. doi: 10.3390/ijms17020187. |
mRNA and microRNA transcriptomics analyses in a murine model of dystrophin loss and therapeutic restoration
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Citation:
Genom Data. 2015 Dec 2;7:88-9. doi: 10.1016/j.gdata.2015.11.025. eCollection 2016 Mar Epub:
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Duchenne muscular dystrophy (DMD) is a pediatric, X-linked, progressive muscle-wasting disorder caused by loss of function... Delivery Method:
peptide-linked Organism or Cell Type:
mice, mdx Citation Extract: Roberts TC, Blomberg KE, Smith CI, El Andaloussi S, Wood MJ. mRNA and microRNA transcriptomics analyses in a murine model of dystrophin loss and therapeutic restoration. Genom Data. 2015 Dec 2;7:88-9. doi: 10.1016/j.gdata.2015.11.025. eCollection 2016 Mar. |
A ligand-independent integrin β1 mechanosensory complex guides spindle orientation
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Citation:
Nat Commun. 2016 Mar 8;7:10899. doi: 10.1038/ncomms10899 Epub:
Not Epub Abstract:
Control of spindle orientation is a fundamental process for embryonic development, morphogenesis and tissue homeostasis, while... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Petridou NI, Skourides PA. A ligand-independent integrin β1 mechanosensory complex guides spindle orientation. Nat Commun. 2016 Mar 8;7:10899. doi: 10.1038/ncomms10899. |