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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Phosphorylation states change Otx2 activity for cell proliferation and patterning in the Xenopus embryo
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Citation:
Development. 2018 Mar 12;145(5). pii: dev159640. doi: 10.1242/dev.159640 Epub:
Not Epub Abstract:
The homeodomain transcription factor Otx2 has essential roles in head and eye formation via the negative and positive... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Satou Y, Minami K, Hosono E, Okada H, Yasuoka Y, Shibano T, Tanaka T, Taira M. Phosphorylation states change Otx2 activity for cell proliferation and patterning in the Xenopus embryo. Development. 2018 Mar 12;145(5). pii: dev159640. doi: 10.1242/dev.159640. |
Time-lapse observation of stepwise regression of Erk activity in zebrafish presomitic mesoderm
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Citation:
Sci Rep. 2018 Mar 12;8(1):4335. doi: 10.1038/s41598-018-22619-9 Epub:
Not Epub Abstract:
During somite segmentation, clock genes oscillate within the posterior presomitic mesoderm (PSM). The temporal information ties... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sari DWK, Akiyama R, Naoki H, Ishijima H, Bessho Y, Matsui T. Time-lapse observation of stepwise regression of Erk activity in zebrafish presomitic mesoderm. Sci Rep. 2018 Mar 12;8(1):4335. doi: 10.1038/s41598-018-22619-9. |
GABA promotes survival and axonal regeneration in identifiable descending neurons after spinal cord injury in larval lampreys
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Citation:
bioRxiv. 2018:[preprint] doi:10.1101/280891 Epub:
Yes Abstract:
In mammals, spinal cord injury (SCI) causes permanent disability. The poor regenerative capacity of descending neurons is one... Delivery Method:
Gelfoam at lesion Organism or Cell Type:
Petromyzon marinus (lamprey) Citation Extract: Romaus-Sanjurjo D, Ledo-Garcia R, Fernandez-Lopez B, Hanslik K, Morgan JR, Barreiro-Iglesias A, Rodicio MC. GABA promotes survival and axonal regeneration in identifiable descending neurons after spinal cord injury in larval lampreys. bioRxiv. 2018:[preprint] doi:10.1101/280891 . |
Polycystin-1 loss-of-function is directly linked to an imbalance in G-Protein signaling in the kidney
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Citation:
Development. 2018 Mar 12. pii: dev.158931. doi: 10.1242/dev.158931. [Epub ahead of print] Epub:
Not Epub Abstract:
The development of the kidney relies on the establishment and maintenance of a precise tubular diameter of its functional units... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Zhang B, Tran U, Wessely O. Polycystin-1 loss-of-function is directly linked to an imbalance in G-Protein signaling in the kidney. Development. 2018 Mar 12. pii: dev.158931. doi: 10.1242/dev.158931. [Epub ahead of print]. |
A zebrafish model for FHL1-opathy reveals loss-of-function effects of human FHL1 mutations
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Citation:
Neuromusc Disord. 2018;[Epub ahead of print] doi:10.1016/j.nmd.2018.03.001 Epub:
Yes Abstract:
Missense mutations in the four and a half LIM domain 1 (FHL1) gene were found to cause X-linked inherited myopathies of both... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Keßler M, Kieltsch A, Kayvanpour E, Katus HA, Schoser B, Schessl J, Just S, Rottbauer W. A zebrafish model for FHL1-opathy reveals loss-of-function effects of human FHL1 mutations. Neuromusc Disord. 2018;[Epub ahead of print] doi:10.1016/j.nmd.2018.03.001. |
TBX20 Regulates Angiogenesis Through the PROK2-PROKR1 Pathway
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Citation:
Circulation. 2018 Mar 15. pii: CIRCULATIONAHA.118.033939. doi: 10.1161/CIRCULATIONAHA.118.033939. [Epub ahead of print] Epub:
Yes Abstract:
Background -Angiogenesis is integral for embryogenesis, and targeting angiogenesis improves the outcome of many pathological... Organism or Cell Type:
zebrafish Citation Extract: Meng S, Gu Q, Yang X, Lv J, Owusu I, Matrone G, Chen K, Cooke JP, Fang L. TBX20 Regulates Angiogenesis Through the PROK2-PROKR1 Pathway. Circulation. 2018 Mar 15. pii: CIRCULATIONAHA.118.033939. doi: 10.1161/CIRCULATIONAHA.118.033939. [Epub ahead of print]. |
Pitx1 regulates cement gland development in Xenopus laevis through activation of transcriptional targets and inhibition of BMP signaling
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Citation:
Dev Biol. 2018 Mar 9. pii: S0012-1606(17)30225-7. doi: 10.1016/j.ydbio.2018.03.008. [Epub ahead of print] Epub:
Yes Abstract:
The cement gland in Xenopus laevis has long been used as a model to study the interplay of cell signaling and transcription... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Jin Y, Weinstein DC. Pitx1 regulates cement gland development in Xenopus laevis through activation of transcriptional targets and inhibition of BMP signaling. Dev Biol. 2018 Mar 9. pii: S0012-1606(17)30225-7. doi: 10.1016/j.ydbio.2018.03.008. [Epub ahead of print]. |
Scribble influences cyst formation in autosomal-dominant polycystic kidney disease by regulating Hippo signaling pathway
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Citation:
FASEB J. 2018 Mar 12:fj201701376RR. doi: 10.1096/fj.201701376RR. [Epub ahead of print] Epub:
Yes Abstract:
Polarity complexes, including the PAR (Partitioning-defective), CRB (Crumbs) and SCRIB (Scribble) complexes, are required for... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Xu D, Lv J, He L, Fu L, Hu R, Cao Y, Mei C. Scribble influences cyst formation in autosomal-dominant polycystic kidney disease by regulating Hippo signaling pathway. FASEB J. 2018 Mar 12:fj201701376RR. doi: 10.1096/fj.201701376RR. [Epub ahead of print]. |
Role of zebrafish fhl1A in satellite cell and skeletal muscle development
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Citation:
Curr Mol Med. 2018 Mar 7. doi: 10.2174/1566524018666180308113909. [Epub ahead of print] Epub:
Yes Abstract:
Four-and-a-half LIM domains protein 1 (FHL1) mutations are associated with human myopathies. However, the function of this... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen F, Yuan W, Mo X, Zhuang J, Wang Y, Chen J, Jiang Z, Zhu X, Zeng Q, Wan Y, Li F, Shi Y, Cao L, Fan X, Luo S, Ye X, Chen Y, Dai G, Gao J, Wang X, Xie H, Zhu P, Li Y, Wu X. Role of zebrafish fhl1A in satellite cell and skeletal muscle development. Curr Mol Med. 2018 Mar 7. doi: 10.2174/1566524018666180308113909. [Epub ahead of print]. |
Morpholino-mediated in vivo silencing of Cryptosporidium parvum lactate dehydrogenase decreases oocyst shedding and infectivity
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Citation:
Int J Parasitol. 2018 Mar 9. pii: S0020-7519(18)30056-0. doi: 10.1016/j.ijpara.2018.01.005. [Epub ahead of print] Epub:
Yes Abstract:
Cryptosporidium is a highly prevalent protozoan parasite that is the second leading cause of childhood morbidity and mortality... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Cryptosporidium parvum Citation Extract: Zhang X, Kim CY, Worthen T, Witola WH. Morpholino-mediated in vivo silencing of Cryptosporidium parvum lactate dehydrogenase decreases oocyst shedding and infectivity. Int J Parasitol. 2018 Mar 9. pii: S0020-7519(18)30056-0. doi: 10.1016/j.ijpara.2018.01.005. [Epub ahead of print]. |