You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Genetic Reduction in Left Ventricular Protein Kinase C-α and Adverse Ventricular Remodeling in Human Subjects

Authors:
Hu R, Morley MP, Brandimarto J, Tucker NR, Parsons VA, Zhao SD, Meder B, Katus HA, Rühle F, Stoll M, Villard E, Cambien F, Lin H, Smith NL, Felix JF, Vasan RS, van der Harst P, Newton-Cheh C, Li J, Kim CE, Hakonarson H, Hannenhalli S, Ashley EA, Moravec CS, Tang WHW, Maillet M, Molkentin JD, Ellinor PT, Margulies KB, Cappola TP
Citation:
Circ Genom Precis Med. 2018 Mar;11(3):e001901. doi: 10.1161/CIRCGEN.117.001901
Epub:
Yes
Abstract:
BACKGROUND: Inhibition of PKC-α (protein kinase C-α) enhances contractility and cardioprotection in animal models, but effects...
Link:
http://circgenetics.ahajournals.org/content/11/3/e001901
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hu R, Morley MP, Brandimarto J, Tucker NR, Parsons VA, Zhao SD, Meder B, Katus HA, Rühle F, Stoll M, Villard E, Cambien F, Lin H, Smith NL, Felix JF, Vasan RS, van der Harst P, Newton-Cheh C, Li J, Kim CE, Hakonarson H, Hannenhalli S, Ashley EA, Moravec CS, Tang WHW, Maillet M, Molkentin JD, Ellinor PT, Margulies KB, Cappola TP. Genetic Reduction in Left Ventricular Protein Kinase C-α and Adverse Ventricular Remodeling in Human Subjects. Circ Genom Precis Med. 2018 Mar;11(3):e001901. doi: 10.1161/CIRCGEN.117.001901.

Successful Knockdown of Aquaporin 1 (AQP1) Protein Expression in American Eel (Anguilla rostrata) Gastrointestinal Tract Using Direct-Infusions of Vivo-Morpholinos

Authors:
Cutler CP, Tanner P
Citation:
The Bulletin: Mount Desert Island Biological Laboratory. 2014;53:12-13
Epub:
Not Epub
Abstract:
Vivo-morpholinos are artificial nucleic acids that can block the protein production from a particular gene. Direct intestinal...
Link:
https://mdibl.org/bulletin/2014/Welcome.html
Delivery Method:
Vivo-morpholino
Organism or Cell Type:
Anguilla rostrata (American eel)
Citation Extract:
Cutler CP, Tanner P. Successful Knockdown of Aquaporin 1 (AQP1) Protein Expression in American Eel (Anguilla rostrata) Gastrointestinal Tract Using Direct-Infusions of Vivo-Morpholinos. The Bulletin: Mount Desert Island Biological Laboratory. 2014;53:12-13.

March2 is required for head formation by mediating Dishevelled degradation in concert with Dapper1

Authors:
Lee H, Cheong SM, Han W, Koo Y, Jo SB, Cho GS, Yang JS, Kim S, Han JK
Citation:
Development. 2018 Mar 16. pii: dev.143107. doi: 10.1242/dev.143107. [Epub ahead of print]
Epub:
Yes
Abstract:
Dishevelled (Dvl/Dsh) is a key scaffold protein that propagates Wnt signaling essential for embryogenesis and homeostasis....
Link:
http://dev.biologists.org/content/early/2018/03/15/dev.143107
Organism or Cell Type:
Xenopus
Citation Extract:
Lee H, Cheong SM, Han W, Koo Y, Jo SB, Cho GS, Yang JS, Kim S, Han JK. March2 is required for head formation by mediating Dishevelled degradation in concert with Dapper1. Development. 2018 Mar 16. pii: dev.143107. doi: 10.1242/dev.143107. [Epub ahead of print].

Cdc42 controls primary mesenchyme cell morphogenesis in the sea urchin embryo

Authors:
Sepúlveda-Ramírez SP, Toledo-Jacobo L, Henson JH, Shuster CB
Citation:
Dev Biol. 2018 Mar 16. pii: S0012-1606(17)30779-0. doi: 10.1016/j.ydbio.2018.03.015. [Epub ahead of print]
Epub:
Yes
Abstract:
In the sea urchin embryo, gastrulation is characterized by the ingression and directed cell migration of primary mesenchyme...
Link:
https://www.sciencedirect.com/science/article/pii/S0012160617307790
Organism or Cell Type:
sea urchin
Citation Extract:
Sepúlveda-Ramírez SP, Toledo-Jacobo L, Henson JH, Shuster CB. Cdc42 controls primary mesenchyme cell morphogenesis in the sea urchin embryo. Dev Biol. 2018 Mar 16. pii: S0012-1606(17)30779-0. doi: 10.1016/j.ydbio.2018.03.015. [Epub ahead of print].

An optimized pipeline for parallel image-based quantification of gene expression and genotyping after in situ hybridization

Authors:
Dobrzycki T, Krecsmarik M, Bonkhofer F, Patient R, Monteiro R
Citation:
Biol Open. 2018 Mar 13. pii: bio.031096. doi: 10.1242/bio.031096. [Epub ahead of print]
Epub:
Yes
Abstract:
Advances in genome engineering have resulted in the generation of numerous zebrafish mutant lines. A commonly used method to...
Link:
http://bio.biologists.org/content/early/2018/03/12/bio.031096.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dobrzycki T, Krecsmarik M, Bonkhofer F, Patient R, Monteiro R. An optimized pipeline for parallel image-based quantification of gene expression and genotyping after in situ hybridization. Biol Open. 2018 Mar 13. pii: bio.031096. doi: 10.1242/bio.031096. [Epub ahead of print].

Dynamics of two key maternal factors that initiate zygotic regulatory programs in ascidian embryos

Authors:
Oda-Ishii I, Abe T, Satou Y
Citation:
Dev Biol. 2018 Mar 14. pii: S0012-1606(18)30031-9. doi: 10.1016/j.ydbio.2018.03.009. [Epub ahead of print]
Epub:
Yes
Abstract:
In animal embryos, transcription is repressed for a definite period of time after fertilization. In the embryo of the ascidian...
Link:
https://www.sciencedirect.com/science/article/pii/S0012160618300319
Delivery Method:
microinjection
Organism or Cell Type:
Ciona intestinalis (ascidian)
Citation Extract:
Oda-Ishii I, Abe T, Satou Y. Dynamics of two key maternal factors that initiate zygotic regulatory programs in ascidian embryos. Dev Biol. 2018 Mar 14. pii: S0012-1606(18)30031-9. doi: 10.1016/j.ydbio.2018.03.009. [Epub ahead of print].

Motor axon navigation relies on Fidgetin-like 1-driven microtubule plus end dynamics

Authors:
Fassier C, Fréal A, Gasmi L, Delphin C, Ten Martin D, De Gois S, Tambalo M, Bosc C, Mailly P, Revenu C, Peris L, Bolte S, Schneider-Maunoury S, Houart C, Nothias F, Larcher JC, Andrieux A, Hazan J
Citation:
J Cell Biol. 2018 Mar 13. pii: jcb.201604108. doi: 10.1083/jcb.201604108. [Epub ahead of print]
Epub:
Yes
Abstract:
During neural circuit assembly, extrinsic signals are integrated into changes in growth cone (GC) cytoskeleton underlying axon...
Link:
http://jcb.rupress.org/content/early/2018/03/12/jcb.201604108
Organism or Cell Type:
zebrafish
Citation Extract:
Fassier C, Fréal A, Gasmi L, Delphin C, Ten Martin D, De Gois S, Tambalo M, Bosc C, Mailly P, Revenu C, Peris L, Bolte S, Schneider-Maunoury S, Houart C, Nothias F, Larcher JC, Andrieux A, Hazan J. Motor axon navigation relies on Fidgetin-like 1-driven microtubule plus end dynamics. J Cell Biol. 2018 Mar 13. pii: jcb.201604108. doi: 10.1083/jcb.201604108. [Epub ahead of print].

TGF-ß Regulates Cathepsin Activation during Normal and Pathogenic Development

Authors:
Flanagan-Steet H, Christian C, Lu PN, Aarnio-Peterson M, Sanman L, Archer-Hartmann S, Azadi P, Bogyo M, Steet RA
Citation:
Cell Rep. 2018 Mar 13;22(11):2964-2977. doi: 10.1016/j.celrep.2018.02.066
Epub:
Not Epub
Abstract:
Cysteine cathepsins play roles during development and disease beyond their function in lysosomal protein turnover. Here, we...
Link:
http://www.cell.com/cell-reports/fulltext/S2211-1247(18)30260-2
Organism or Cell Type:
zebrafish
Citation Extract:
Flanagan-Steet H, Christian C, Lu PN, Aarnio-Peterson M, Sanman L, Archer-Hartmann S, Azadi P, Bogyo M, Steet RA. TGF-ß Regulates Cathepsin Activation during Normal and Pathogenic Development. Cell Rep. 2018 Mar 13;22(11):2964-2977. doi: 10.1016/j.celrep.2018.02.066.

Mir-126 is a conserved modulator of lymphatic development

Authors:
Kontarakis Z, Rossi A, Ramas S, Dellinger MT, Stainier DYR
Citation:
Dev Biol. 2018 Mar 14. pii: S0012-1606(18)30138-6. doi: 10.1016/j.ydbio.2018.03.006. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Organ homeostasis relies upon cellular and molecular processes that restore tissue structure and function in a timely fashion....
Link:
https://www.sciencedirect.com/science/article/pii/S0012160618301386
Organism or Cell Type:
zebrafish
Citation Extract:
Kontarakis Z, Rossi A, Ramas S, Dellinger MT, Stainier DYR. Mir-126 is a conserved modulator of lymphatic development. Dev Biol. 2018 Mar 14. pii: S0012-1606(18)30138-6. doi: 10.1016/j.ydbio.2018.03.006. [Epub ahead of print].

Analysis of hpf1 expression and function in early embryonic development of zebrafish

Authors:
Zhang Z, Sun H, Chen Y, Cao T, Songyang Z, Huang J, Huang Y
Citation:
Dev Genes Evol. 2018 Mar 17. doi: 10.1007/s00427-018-0608-9. [Epub ahead of print]
Epub:
Yes
Abstract:
About 70% of zebrafish (Danio rerio) genes are orthologues of the human's, which are of great interests, but still largely...
Link:
https://link.springer.com/article/10.1007/s00427-018-0608-9
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Z, Sun H, Chen Y, Cao T, Songyang Z, Huang J, Huang Y. Analysis of hpf1 expression and function in early embryonic development of zebrafish. Dev Genes Evol. 2018 Mar 17. doi: 10.1007/s00427-018-0608-9. [Epub ahead of print].

Pages