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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Roles of progesterone receptor membrane component 1 and membrane progestin receptor alpha in regulation of zebrafish oocyte maturation
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Citation:
Gen Comp Endocrinol. 2018 Apr 9. pii: S0016-6480(17)30757-8. doi: 10.1016/j.ygcen.2018.04.009. [Epub ahead of print] Epub:
Yes Abstract:
Although previous studies suggest membrane progesterone receptor alpha (mPRα/Paqr7) mediates 17, 20β-dihydroxy-4-pregnen-3-one... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Aizen J, Pang Y, Harris C, Converse A, Zhu Y, Aguirre MA, Thomas P. Roles of progesterone receptor membrane component 1 and membrane progestin receptor alpha in regulation of zebrafish oocyte maturation. Gen Comp Endocrinol. 2018 Apr 9. pii: S0016-6480(17)30757-8. doi: 10.1016/j.ygcen.2018.04.009. [Epub ahead of print]. |
Systemic administration of the antisense oligonucleotide NS-065/NCNP-01 for skipping of exon 53 in patients with Duchenne muscular dystrophy
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Citation:
Sci Transl Med. 2018 Apr 18;10(437). pii: eaan0713. doi: 10.1126/scitranslmed.aan0713 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is a lethal hereditary muscle disease caused by mutations in the gene encoding the muscle... Delivery Method:
i.v. infusion Organism or Cell Type:
human Citation Extract: Komaki H, Nagata T, Saito T, Masuda S, Takeshita E, Sasaki M, Tachimori H, Nakamura H, Aoki Y, Takeda S. Systemic administration of the antisense oligonucleotide NS-065/NCNP-01 for skipping of exon 53 in patients with Duchenne muscular dystrophy. Sci Transl Med. 2018 Apr 18;10(437). pii: eaan0713. doi: 10.1126/scitranslmed.aan0713. |
Dual Molecular Effects of Dominant RORA Mutations Cause Two Variants of Syndromic Intellectual Disability with Either Autism or Cerebellar Ataxia
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Citation:
Am J Hum Genet. 2018;[Epub ahead of print] doi:10.1016/j.ajhg.2018.02.021 Epub:
Not Epub Abstract:
RORα, the RAR-related orphan nuclear receptor alpha, is essential for cerebellar development. The spontaneous mutant mouse... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Guissart C, Latypova X, Rollier P, Khan TN, Stamberger H, McWalter K, Cho MT, Kjaergaard S, Weckhuysen S, Lesca G, Besnard T, Õunap K, Schema J, Chiocchetti AG, McDonald M, de Bellescize J, Vincent M, Van Esch H, Sattler S, Forghani I, Thiffault I, Freitag CM, Barbouth DS, Cadieux-Dion M, Willaert R, Sacoto MJG, Safina NP, Dubourg C, Grote L, Carré W, Saunders C, Pajusalu S, Farrow E, Boland A, Karlowicz DH, Deleuze J-F, Wojcik MH, Pressman R, Isidor B, Vogels A, Van Paesschen W, Al-Gazali J, Al Shamsi AM, Claustres M, Pujol A, Sanders SJ, Rivier F, Leboucq N, Cogné B, Sasorith S, Sanlaville D, Retterer K, Odent S, Katsanis N, Bézieau S, Koenig M, Davis EE, Pasquier L, Küry S. Dual Molecular Effects of Dominant RORA Mutations Cause Two Variants of Syndromic Intellectual Disability with Either Autism or Cerebellar Ataxia. Am J Hum Genet. 2018;[Epub ahead of print] doi:10.1016/j.ajhg.2018.02.021. |
Calcium Signals Act Through Histone Deacetylase to Mediate Pronephric Kidney Morphogenesis
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Citation:
Dev Dyn. 2018 Apr 6. doi: 10.1002/dvdy.24632. [Epub ahead of print] Epub:
Not Epub Abstract:
BACKGROUND: Autosomal dominant polycystic kidney disease is the most common monogenetic kidney disorder and is linked to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rothschild SC, Lee HJ, Ingram SR, Mohammadi DK, Walsh GS, Tombes RM. Calcium Signals Act Through Histone Deacetylase to Mediate Pronephric Kidney Morphogenesis. Dev Dyn. 2018 Apr 6. doi: 10.1002/dvdy.24632. [Epub ahead of print]. |
Synaptically silent sensory hair cells in zebrafish are recruited after damage
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Citation:
Nat Comm. 2018;9:1388. doi:10.1038/s41467-018-03806-8 Epub:
Not Epub Abstract:
Analysis of mechanotransduction among ensembles of sensory hair cells in vivo is challenging in many species. To overcome this... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang Q, Li S, Wong H-TC, He XJ, Beirl A, Petralia RS, Wang Y-X, Kindt KS. Synaptically silent sensory hair cells in zebrafish are recruited after damage. Nat Comm. 2018;9:1388. doi:10.1038/s41467-018-03806-8. |
Blocking variant surface glycoprotein synthesis alters endoplasmic reticulum exit sites/Golgi homeostasis in Trypanosoma brucei
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Citation:
Traffic. 2018;[Epub] doi:10.1111/tra.12561 Epub:
Yes Abstract:
The predominant secretory cargo of bloodstream form Trypanosoma brucei is variant surface glycoprotein (VSG), comprising ~10%... Delivery Method:
electroporation Organism or Cell Type:
Trypanosoma brucei Citation Extract: Ooi C-P, Smith TK, Gluenz E, Vasileva Wand NV, Vaughan S, Rudenko G. Blocking variant surface glycoprotein synthesis alters endoplasmic reticulum exit sites/Golgi homeostasis in Trypanosoma brucei. Traffic. 2018;[Epub] doi:10.1111/tra.12561. |
An Early Function of Polycystin-2 for Left-Right Organizer Induction in Xenopus
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Citation:
iScience. 2018;2:76-85. doi:10.1016/j.isci.2018.03.011 Epub:
Not Epub Abstract:
Nodal signaling controls asymmetric organ placement during vertebrate embryogenesis. Nodal is induced by a leftward fluid flow... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Vick P, Kreis J, Schneider I, Tingler M, Getwan M, Thumberger T, Beyer T, Schweickert A, Blum M. An Early Function of Polycystin-2 for Left-Right Organizer Induction in Xenopus. iScience. 2018;2:76-85. doi:10.1016/j.isci.2018.03.011 . |
Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights
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Citation:
Nat Genet. 2018;[Epub ahead of print] doi:10.1038/s41588-018-0092-1 Epub:
Yes Abstract:
Genome-wide association studies (GWAS) have identified over 100 risk loci for schizophrenia, but the causal mechanisms remain... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gusev A, Mancuso N, Won H, Kousi M, Finucane HK, Reshef Y, Song L, Safi A, Schizophrenia Working Group of the Psychiatric Genomics Consortium, McCarroll S, Neale BM, Ophoff RA, O’Donovan MC, Crawford GE, Geschwind DH, Katsanis N, Sullivan PF, Pasaniuc B, Price AL. Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights. Nat Genet. 2018;[Epub ahead of print] doi:10.1038/s41588-018-0092-1. |
Transgenic Xenopus laevis Line for In Vivo Labeling of Nephrons within the Kidney
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Citation:
Genes. 2018;9(4):197. doi:10.3390/genes9040197 Epub:
Not Epub Abstract:
Xenopus laevis embryos are an established model for studying kidney development. The nephron structure and genetic pathways... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Corkins ME, Hannah L. Hanania HL, Krneta-Stankic V, DeLay BD, Pearl EJ, Lee M, Ji H, Davidson AJ, Horb ME, Miller RK. Transgenic Xenopus laevis Line for In Vivo Labeling of Nephrons within the Kidney. Genes. 2018;9(4):197. doi:10.3390/genes9040197. |
Machine Learning To Predict Cell-Penetrating Peptides for Antisense Delivery
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Citation:
ACS Cent Sci. 2018;[Epub] doi:10.1021/acscentsci.8b00098 Epub:
Yes Abstract:
Cell-penetrating peptides (CPPs) can facilitate the intracellular delivery of large therapeutically relevant molecules,... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: HeLa 654 Citation Extract: Wolfe JM, Fadzen CM, Choo Z-N, Rebecca L. Holden RL, Yao M, Hanson GJ, Pentelute BL. Machine Learning To Predict Cell-Penetrating Peptides for Antisense Delivery. ACS Cent Sci. 2018;[Epub] doi:10.1021/acscentsci.8b00098. |