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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Evolution of nitric oxide regulation of gut function

Authors:
Yaguchi J, Yaguchi S
Citation:
Proc Nat Acad Sci USA. 2019;[Epub ahead of print] doi:10.1073/pnas.1816973116
Epub:
Yes
Abstract:
Although morphologies are diverse, the common pattern in bilaterians is for passage of food in the gut to be controlled by...
Delivery Method:
microinjection
Organism or Cell Type:
Hemicentrotus pulcherrimus (sea urchin)
Citation Extract:
Yaguchi J, Yaguchi S. Evolution of nitric oxide regulation of gut function. Proc Nat Acad Sci USA. 2019;[Epub ahead of print] doi:10.1073/pnas.1816973116.

The selective autophagy receptors Optineurin and p62 are both required for zebrafish host resistance to mycobacterial infection

Authors:
Zhang R, Varela M, Vallentgoed W, Forn-Cuni G, van der Vaart M, Meijer AH
Citation:
PLoS Pathog. 2019;15(2):e1007329. doi:10.1371/journal.ppat.1007329
Epub:
Not Epub
Abstract:
Mycobacterial pathogens are the causative agents of chronic infectious diseases like tuberculosis and leprosy. Autophagy has...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang R, Varela M, Vallentgoed W, Forn-Cuni G, van der Vaart M, Meijer AH. The selective autophagy receptors Optineurin and p62 are both required for zebrafish host resistance to mycobacterial infection. PLoS Pathog. 2019;15(2):e1007329. doi:10.1371/journal.ppat.1007329.

Zebrafish prdm12b acts independently of nkx6.1 repression to promote eng1b expression in the neural tube p1 domain

Authors:
Yildiz O, Downes GB, Sagerström CG
Citation:
Neural Dev. 2019;14:5. doi:10.1186/s13064-019-0129-x
Epub:
Not Epub
Abstract:
Background: Functioning of the adult nervous system depends on the establishment of neural circuits during embryogenesis. In...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yildiz O, Downes GB, Sagerström CG. Zebrafish prdm12b acts independently of nkx6.1 repression to promote eng1b expression in the neural tube p1 domain. Neural Dev. 2019;14:5. doi:10.1186/s13064-019-0129-x.

Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependent pigment progenitors in zebrafish

Authors:
Camargo-Sosa K, Colanesi S, Müller J, Schulte-Merker S, Stemple D, Patton EE, Kelsh RN
Citation:
PLoS Genet. 2019;15(2):e1007941. doi:10.1371/journal.pgen.1007941
Epub:
Not Epub
Abstract:
Skin pigment patterns are important, being under strong selection for multiple roles including camouflage and UV protection....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Camargo-Sosa K, Colanesi S, Müller J, Schulte-Merker S, Stemple D, Patton EE, Kelsh RN . Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependent pigment progenitors in zebrafish. PLoS Genet. 2019;15(2):e1007941. doi:10.1371/journal.pgen.1007941.

Mutations in the Glycosyltransferase Domain of GLT8D1 Are Associated with Familial Amyotrophic Lateral Sclerosis

Authors:
Cooper-Knock J, Moll T, Ramesh T, Castelli L, Beer A, Robins H, Fox I, Niedermoser I, Van Damme P, Moisse M, Robberecht W, Hardiman O, Panades MP, Assialioui A, Mora JS, Basak AN, Morrison KE, Shaw CE, Al-Chalabi A, Landers JE, Wyles M, Heath PR, Higginbottom A, Walsh T, Kazoka M, McDermott CJ, Hautbergue GM, Kirby J, Shaw PJ
Citation:
Cell Rep. 2019;26(9):2298-306. doi:10.1016/j.celrep.2019.02.006
Epub:
Not Epub
Abstract:
Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disorder without effective neuroprotective therapy. Known...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cooper-Knock J, Moll T, Ramesh T, Castelli L, Beer A, Robins H, Fox I, Niedermoser I, Van Damme P, Moisse M, Robberecht W, Hardiman O, Panades MP, Assialioui A, Mora JS, Basak AN, Morrison KE, Shaw CE, Al-Chalabi A, Landers JE, Wyles M, Heath PR, Higginbottom A, Walsh T, Kazoka M, McDermott CJ, Hautbergue GM, Kirby J, Shaw PJ. Mutations in the Glycosyltransferase Domain of GLT8D1 Are Associated with Familial Amyotrophic Lateral Sclerosis. Cell Rep. 2019;26(9):2298-306. doi:10.1016/j.celrep.2019.02.006.

A familial congenital heart disease with a possible multigenic origin involving a mutation in BMPR1A

Authors:
Demal TJ, Heise M, Reiz B, Dogra D, Brænne I, Reichenspurner H, Männer J, Aherrahrou Z, Schunkert H, Erdmann J, Abdelilah-Seyfried S
Citation:
Sci Rep. 2019;9:2959. doi:10.1038/s41598-019-39648-7
Epub:
Not Epub
Abstract:
The genetics of many congenital heart diseases (CHDs) can only unsatisfactorily be explained by known chromosomal or Mendelian...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Demal TJ, Heise M, Reiz B, Dogra D, Brænne I, Reichenspurner H, Männer J, Aherrahrou Z, Schunkert H, Erdmann J, Abdelilah-Seyfried S. A familial congenital heart disease with a possible multigenic origin involving a mutation in BMPR1A. Sci Rep. 2019;9:2959. doi:10.1038/s41598-019-39648-7.

Fluid dynamics during bleb formation in migrating cells in vivo

Authors:
Goudarzi M, Boquet-Pujadas A, Olivo-Marin J-C, Raz E
Citation:
PLoS ONE. 2019;14(2): e0212699. doi:10.1371/journal.pone.0212699
Epub:
Not Epub
Abstract:
Blebs are cellular protrusions observed in migrating cells and in cells undergoing spreading, cytokinesis, and apoptosis. Here...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Goudarzi M, Boquet-Pujadas A, Olivo-Marin J-C, Raz E. Fluid dynamics during bleb formation in migrating cells in vivo. PLoS ONE. 2019;14(2): e0212699. doi:10.1371/journal.pone.0212699.

The wnt inhibitor Dkk1 is required for maintaining the normal cardiac differentiation program in Xenopus laevis

Authors:
Guo Y, Dorn T, Kühl SJ, Linnemann A, Rothe M, Pfister AS, Vainio S, Laugwitz KL, Moretti A, Kühl M
Citation:
Dev Biol. 2019 Feb 21. pii: S0012-1606(18)30559-1. doi: 10.1016/j.ydbio.2019.02.009. [Epub ahead of print]
Epub:
Yes
Abstract:
Wnt proteins can activate different intracellular signaling pathways. These pathways need to be tightly regulated for proper...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Guo Y, Dorn T, Kühl SJ, Linnemann A, Rothe M, Pfister AS, Vainio S, Laugwitz KL, Moretti A, Kühl M. The wnt inhibitor Dkk1 is required for maintaining the normal cardiac differentiation program in Xenopus laevis. Dev Biol. 2019 Feb 21. pii: S0012-1606(18)30559-1. doi: 10.1016/j.ydbio.2019.02.009. [Epub ahead of print].

ClC-7 Regulates the Pattern and Early Development of Craniofacial Bone and Tooth

Authors:
Zhang Y, Ji D, Li L, Yang S, Zhang H, Duan X
Citation:
Theranostics. 2019;9(5):1387-1400. doi:10.7150/thno.29761
Epub:
Not Epub
Abstract:
Human CLCN7 encodes voltage-gated chloride channel 7 (ClC-7); mutations of CLCN7 lead to osteopetrosis which is characterized...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Y, Ji D, Li L, Yang S, Zhang H, Duan X. ClC-7 Regulates the Pattern and Early Development of Craniofacial Bone and Tooth. Theranostics. 2019;9(5):1387-1400. doi:10.7150/thno.29761.

Tulotta C, Stefanescu C, Chen Q, Torraca V, Meijer AH, Snaar-Jagalska BE

Authors:
CXCR4 signaling regulates metastatic onset by controlling neutrophil motility and response to malignant cells
Citation:
Sci Rep. 2019;9:2399 doi:10.1038/s41598-019-38643-2
Epub:
Not Epub
Abstract:
Developing tumors interact with the surrounding microenvironment. Myeloid cells exert both anti- and pro-tumor functions and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
CXCR4 signaling regulates metastatic onset by controlling neutrophil motility and response to malignant cells. Tulotta C, Stefanescu C, Chen Q, Torraca V, Meijer AH, Snaar-Jagalska BE. Sci Rep. 2019;9:2399 doi:10.1038/s41598-019-38643-2.

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