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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Mechanosensing by the lamina protects against nuclear rupture, DNA damage, and cell cycle arrest

Authors:
Cho S, Vashisth M, Abbas A, Majkutv S, Vogel K, Xia Y, Ivanovska IL, Irianto J, Tewari M, Zhu K, Tichy ED, Mourkioti F, Tang H-Y, Greenberg R, Prosser BL, Discher DE
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/583179
Epub:
Not Epub
Abstract:
Whether cell forces or extracellular matrix (ECM) can impact genome integrity is largely unclear. Here, acute perturbations (~...
Link:
https://www.biorxiv.org/content/10.1101/583179v1
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
organ culture: Gallus gallus (chick) hearts
Citation Extract:
Cho S, Vashisth M, Abbas A, Majkutv S, Vogel K, Xia Y, Ivanovska IL, Irianto J, Tewari M, Zhu K, Tichy ED, Mourkioti F, Tang H-Y, Greenberg R, Prosser BL, Discher DE. Mechanosensing by the lamina protects against nuclear rupture, DNA damage, and cell cycle arrest. bioRxiv. 2019;[preprint] doi:10.1101/583179.

Posterior axis formation requires Dlx5/Dlx6 expression at the neural plate border

Authors:
Narboux-Neme N, Ekker M, Levi G, Heude E
Citation:
PLoS ONE. 2019;14(3):e0214063. https://doi.org/10.1371/journal.pone.0214063
Epub:
Not Epub
Abstract:
Neural tube defects (NTDs), one of the most common birth defects in human, present a multifactorial etiology with a poorly...
Link:
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214063
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Narboux-Neme N, Ekker M, Levi G, Heude E. Posterior axis formation requires Dlx5/Dlx6 expression at the neural plate border. PLoS ONE. 2019;14(3):e0214063. https://doi.org/10.1371/journal.pone.0214063.

Morpholino-induced exon skipping stimulates cell-mediated and humoral responses to dystrophin in mdx mice

Authors:
Vila MC, Novak JS, Benny Klimek M, Li N, Morales M, Fritz AG, Edwards K, Boehler JF, Hogarth MW, Kinder TB, Zhang A, Mazala D, Fiorillo AA, Douglas B, Chen YW, van den Anker J, Lu QL, Hathout Y, Hoffman EP, Partridge TA, Nagaraju K
Citation:
J Pathol. 2019 Mar 18. doi: 10.1002/path.5263. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Exon skipping is a promising genetic therapeutic strategy for restoring dystrophin expression in the treatment of Duchenne...
Link:
https://onlinelibrary.wiley.com/doi/abs/10.1002/path.5263
Organism or Cell Type:
mice mdx
Citation Extract:
Vila MC, Novak JS, Benny Klimek M, Li N, Morales M, Fritz AG, Edwards K, Boehler JF, Hogarth MW, Kinder TB, Zhang A, Mazala D, Fiorillo AA, Douglas B, Chen YW, van den Anker J, Lu QL, Hathout Y, Hoffman EP, Partridge TA, Nagaraju K. Morpholino-induced exon skipping stimulates cell-mediated and humoral responses to dystrophin in mdx mice. J Pathol. 2019 Mar 18. doi: 10.1002/path.5263. [Epub ahead of print].

Thrombocyte inhibition restores protective immunity to mycobacterial infection in zebrafish

Authors:
Hortle E, Johnson KE, Johansen MD, Nguyen T, Shavit JA, Britton WJ, Tobin DM, Oehlers SH
Citation:
J Infect Dis. 2019 Mar 16. pii: jiz110. doi: 10.1093/infdis/jiz110. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: Infection-induced thrombocytosis is a clinically important complication of tuberculosis infection. Recent studies...
Link:
https://academic.oup.com/jid/advance-article-abstract/doi/10.1093/infdis/jiz110/5381834
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hortle E, Johnson KE, Johansen MD, Nguyen T, Shavit JA, Britton WJ, Tobin DM, Oehlers SH. Thrombocyte inhibition restores protective immunity to mycobacterial infection in zebrafish. J Infect Dis. 2019 Mar 16. pii: jiz110. doi: 10.1093/infdis/jiz110. [Epub ahead of print].

Blockade of a Laminin-411-Notch Axis with CRISPR/Cas9 or a Nanobioconjugate Inhibits Glioblastoma Growth through Tumor-Microenvironment Cross-talk

Authors:
Sun T, Patil R, Galstyan A, Klymyshyn D, Ding H, Chesnokova A, Cavenee WK, Furnari FB, Ljubimov VA, Shatalova ES, Wagner S, Li D, Mamelak AN, Bannykh SI, Patil CG, Rudnick JD, Hu J, Grodzinski ZB, Rekechenetskiy A, Falahatian V, Lyubimov AV, Chen YL, Leoh LS, Daniels-Wells TR, Penichet ML, Holler E, Ljubimov AV, Black KL, Ljubimova JY
Citation:
Cancer Res. 2019 Mar 15;79(6):1239-1251. doi: 10.1158/0008-5472.CAN-18-2725. Epub 2019 Jan 18
Epub:
Not Epub
Abstract:
. . . There is an unmet need for the treatment of glioblastoma multiforme (GBM). The extracellular matrix, including...
Link:
http://cancerres.aacrjournals.org/content/79/6/1239
Delivery Method:
nanoparticles
Organism or Cell Type:
mice with glioblastome xenograft
Citation Extract:
Sun T, Patil R, Galstyan A, Klymyshyn D, Ding H, Chesnokova A, Cavenee WK, Furnari FB, Ljubimov VA, Shatalova ES, Wagner S, Li D, Mamelak AN, Bannykh SI, Patil CG, Rudnick JD, Hu J, Grodzinski ZB, Rekechenetskiy A, Falahatian V, Lyubimov AV, Chen YL, Leoh LS, Daniels-Wells TR, Penichet ML, Holler E, Ljubimov AV, Black KL, Ljubimova JY. Blockade of a Laminin-411-Notch Axis with CRISPR/Cas9 or a Nanobioconjugate Inhibits Glioblastoma Growth through Tumor-Microenvironment Cross-talk. Cancer Res. 2019 Mar 15;79(6):1239-1251. doi: 10.1158/0008-5472.CAN-18-2725. Epub 2019 Jan 18.

A critical role for miR-142 in alveolar epithelial lineage formation in mouse lung development

Authors:
Shrestha A, Carraro G, Nottet N, Vazquez-Armendariz AI, Susanne Herold S, Cordero J, Singh I, Jochen Wilhelm J, Barreto G, Morty R, El Agha E, Mari B, Chen C, Jin-San Zhang J-S, Chao C-M, Bellusci S
Citation:
Cell Molec Life Sci. 2019;[Epub] doi:10.1007/s00018-019-03067-8
Epub:
Yes
Abstract:
The respiratory epithelium arises from alveolar epithelial progenitors which differentiate into alveolar epithelial type 1 (AT1...
Link:
https://link.springer.com/article/10.1007%2Fs00018-019-03067-8
Organism or Cell Type:
lung explants
Citation Extract:
Shrestha A, Carraro G, Nottet N, Vazquez-Armendariz AI, Susanne Herold S, Cordero J, Singh I, Jochen Wilhelm J, Barreto G, Morty R, El Agha E, Mari B, Chen C, Jin-San Zhang J-S, Chao C-M, Bellusci S. A critical role for miR-142 in alveolar epithelial lineage formation in mouse lung development. Cell Molec Life Sci. 2019;[Epub] doi:10.1007/s00018-019-03067-8.

Zebrafish Model for Non-Syndromic X-linked Sensorineural Deafness, DFNX1

Authors:
DeSmidt AA, Zou B, Grati M, Yan D, Mittal R, Yao Q, Richmond MT, Denyer S, Liu XZ, Lu Z
Citation:
Anat Rec (Hoboken). 2019 Mar 15. doi: 10.1002/ar.24115. [Epub ahead of print]
Epub:
Yes
Abstract:
Hereditary deafness is often a neurosensory disorder and affects the quality of life of humans. Only three X-linked genes (POU...
Link:
https://onlinelibrary.wiley.com/doi/abs/10.1002/ar.24115
Organism or Cell Type:
zebrafish
Citation Extract:
DeSmidt AA, Zou B, Grati M, Yan D, Mittal R, Yao Q, Richmond MT, Denyer S, Liu XZ, Lu Z. Zebrafish Model for Non-Syndromic X-linked Sensorineural Deafness, DFNX1. Anat Rec (Hoboken). 2019 Mar 15. doi: 10.1002/ar.24115. [Epub ahead of print].

cMet signaling functions during zebrafish hindbrain development

Authors:
Elsen GE, Choi LY, Prince VE, Ho RK
Citation:
Dev Biol. 2008;329(2):541. doi:10.1016/j.ydbio.2008.05.270
Epub:
Not Epub
Abstract:
During development, cMet signaling regulates a range of cellular processes, including growth, survival and migration (...
Link:
https://www.sciencedirect.com/science/article/pii/S0012160608006015
Organism or Cell Type:
zebrafish
Citation Extract:
Elsen GE, Choi LY, Prince VE, Ho RK. cMet signaling functions during zebrafish hindbrain development. Dev Biol. 2008;329(2):541. doi:10.1016/j.ydbio.2008.05.270.

Chemokine signaling links cell cycle progression and cilia formation for left-right symmetry breaking

Authors:
Liu J, Zhu C, Ning G, Yang L, Cao Y, Huang S, Wang Q
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/578351
Epub:
Not Epub
Abstract:
Zebrafish dorsal forerunner cells (DFCs) undergo vigorous proliferation during epiboly and then exit cell cycle to generate...
Link:
https://www.biorxiv.org/content/10.1101/578351v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu J, Zhu C, Ning G, Yang L, Cao Y, Huang S, Wang Q. Chemokine signaling links cell cycle progression and cilia formation for left-right symmetry breaking. bioRxiv. 2019;[preprint] doi:10.1101/578351.

Possible co-option of a VEGF-driven tubulogenesis program for biomineralization in echinoderms

Authors:
Ben-Tabou de-Leon S, Gildor T, Sher N, Roopin M, Morgulis M, Malik A, Dines M, Lalzar M, Khalaily L
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/554683
Epub:
Not Epub
Abstract:
Biomineralization is the process in which living organisms use minerals to form structures that protect and support them....
Link:
https://www.biorxiv.org/content/10.1101/554683v1
Delivery Method:
microinjection
Organism or Cell Type:
Paracentrotus lividus (sea urchin)
Citation Extract:
Ben-Tabou de-Leon S, Gildor T, Sher N, Roopin M, Morgulis M, Malik A, Dines M, Lalzar M, Khalaily L. Possible co-option of a VEGF-driven tubulogenesis program for biomineralization in echinoderms. bioRxiv. 2019;[preprint] doi:10.1101/554683.

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