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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Loss-of-function approaches in comparative physiology: is there a future for knockdown experiments in the era of genome editing?
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Citation:
J Exp Biol. 2019 Apr 4;222(Pt 7). pii: jeb175737. doi: 10.1242/jeb.175737. Review Epub:
Not Epub Abstract:
Loss-of-function technologies, such as morpholino- and RNAi-mediated gene knockdown, and TALEN- and CRISPR/Cas9-mediated gene... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zimmer AM, Pan YK, Chandrapalan T, Kwong RWM, Perry SF. Loss-of-function approaches in comparative physiology: is there a future for knockdown experiments in the era of genome editing?. J Exp Biol. 2019 Apr 4;222(Pt 7). pii: jeb175737. doi: 10.1242/jeb.175737. Review. |
Prostaglandin signaling regulates renal multiciliated cell specification and maturation
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Citation:
Proc Nat Acad Sci USA. 2019;[Epub ahead of print] doi:10.1073/pnas.1813492116 Epub:
Yes Abstract:
Multiciliated cells (MCCs) are specialized epithelia with apical bundles of motile cilia that direct fluid flow. MCC... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Marra AN, Adeeb BD, Chambers BE, Drummond BE, Ulrich M, Addiego A, Springer M, Poureetezadi SJ, Chambers JM, Ronshaugen M, Wingert RA. Prostaglandin signaling regulates renal multiciliated cell specification and maturation. Proc Nat Acad Sci USA. 2019;[Epub ahead of print] doi:10.1073/pnas.1813492116. |
GPCR-independent activation of G proteins promotes apical cell constriction in vivo
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Citation:
J Cell Biol. 2019;[Epub ahead of print] doi:10.1083/jcb.201811174 Epub:
Yes Abstract:
Heterotrimeric G proteins are signaling switches that control organismal morphogenesis across metazoans. In invertebrates,... Organism or Cell Type:
Xenopus laevis Citation Extract: Marivin A, Morozova V, Walawalkar I, Leyme A, Kretov DA, Cifuentes D, Dominguez I, Garcia-Marcos M. GPCR-independent activation of G proteins promotes apical cell constriction in vivo. J Cell Biol. 2019;[Epub ahead of print] doi:10.1083/jcb.201811174. |
Extracellular Matrix Signaling Through β3 Integrin Mediates Cocaine Cue-induced Transient Synaptic Plasticity and Relapse
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Citation:
Biol Psych. 2019;[Epub ahead of print] doi:10.1016/j.biopsych.2019.03.982 Epub:
Yes Abstract:
Background: Cue-induced relapse to drug use is a primary symptom of cocaine addiction. Cue-induced transient excitatory... Organism or Cell Type:
rats Citation Extract: Garcia-Keller C, Neuhofer D, Bobadilla A-C, Spencer S, Chioma V, Monforton C, Kalivas PW. Extracellular Matrix Signaling Through β3 Integrin Mediates Cocaine Cue-induced Transient Synaptic Plasticity and Relapse. Biol Psych. 2019;[Epub ahead of print] doi:10.1016/j.biopsych.2019.03.982. |
A novel evolutionary conserved mechanism of RNA stability regulates synexpression of primordial germ cell-specific genes prior to the sex-determination stage in medaka
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Citation:
PLoS Biol. 2019;17(4):e3000185. https://doi.org/10.1371/journal.pbio.3000185 Epub:
Not Epub Abstract:
Dmrt1 is a highly conserved transcription factor, which is critically involved in regulation of gonad development of... Delivery Method:
microinjection Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Herpin A, Schmidt C, Kneitz S, Gobé C, Regensburger M, Le Cam A, Montfort J, Adolfi MC, Lillesaar C, Wilhelm D, Kraeussling M, Mourot B, Porcon B, Pannetier M, Pailhoux E, Ettwiller L, Dolle D, Guiguen Y, Schartl M. A novel evolutionary conserved mechanism of RNA stability regulates synexpression of primordial germ cell-specific genes prior to the sex-determination stage in medaka. PLoS Biol. 2019;17(4):e3000185. https://doi.org/10.1371/journal.pbio.3000185. |
The maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo
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Citation:
Nat Comm. 2019;10(1):1551. doi:10.1038/s41467-019-09582-3 Epub:
Not Epub Abstract:
The segregation of eukaryotic genomes into euchromatin and heterochromatin represents a fundamental and poorly understood... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Laue K, Rajshekar S, Courtney AJ, Lewis ZA, Goll MG. The maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo. Nat Comm. 2019;10(1):1551. doi:10.1038/s41467-019-09582-3. |
In vivo topology converts competition for cell-matrix adhesion into directional migration
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Citation:
Nat Comm. 2019;10(1):1518. doi:10.1038/s41467-019-09548-5 Epub:
Not Epub Abstract:
When migrating in vivo, cells are exposed to numerous conflicting signals: chemokines, repellents, extracellular matrix, growth... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Bajanca F, Gouignard N, Colle C, Parsons M, Mayor R, Theveneau E. In vivo topology converts competition for cell-matrix adhesion into directional migration. Nat Comm. 2019;10(1):1518. doi:10.1038/s41467-019-09548-5. |
PTC-bearing mRNA elicits a genetic compensation response via Upf3a and COMPASS components
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Citation:
Nature. 2019;[Epub ahead of print] doi:10.1038/s41586-019-1057-y Epub:
Yes Abstract:
The genetic compensation response (GCR) has recently been proposed as a possible explanation for the phenotypic discrepancies... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ma Z, Zhu P, Shi H, Guo L, Zhang Q, Chen Y, Chen S, Zhang Z, Peng J, Chen J. PTC-bearing mRNA elicits a genetic compensation response via Upf3a and COMPASS components. Nature. 2019;[Epub ahead of print] doi:10.1038/s41586-019-1057-y. |
The Neuromodulator Adenosine Regulates Oligodendrocyte Migration at Motor Exit Point Transition Zones
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Citation:
Cell Rep. 2019;27(1):115-128.E5 doi:10.1016/j.celrep.2019.03.013 Epub:
Not Epub Abstract:
During development, oligodendrocyte progenitor cells (OPCs) migrate extensively throughout the spinal cord. However, their... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fontenas L, Welsh TG, Piller M, Coughenour P, Gandhi AV, Prober DA, Kucenas S. The Neuromodulator Adenosine Regulates Oligodendrocyte Migration at Motor Exit Point Transition Zones. Cell Rep. 2019;27(1):115-128.E5 doi:10.1016/j.celrep.2019.03.013. |
Zebrafish Klf4 maintains the ionocyte progenitor population by regulating epidermal stem cell proliferation and lateral inhibition
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Citation:
PLoS Genet. 2019;15(4):e1008058. doi:10.1371/journal.pgen.1008058 Epub:
Not Epub Abstract:
In the skin and gill epidermis of fish, ionocytes develop alongside keratinocytes and maintain body fluid ionic homeostasis... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen Y-C, Liao B-K, Lu Y-F, Liu Y-H, Hsieh F-C, Hwang P-P, Hwang S-PL. Zebrafish Klf4 maintains the ionocyte progenitor population by regulating epidermal stem cell proliferation and lateral inhibition. PLoS Genet. 2019;15(4):e1008058. doi:10.1371/journal.pgen.1008058. |