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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Photoreceptor progenitor dynamics in the zebrafish embryo retina and its modulation by primary cilia and N-cadherin

Authors:
Aparicio G, Rodao M, Badano JL, Zolessi FR
Citation:
Int J Dev Biol. 2020 Aug 25. doi: 10.1387/ijdb.200113fz. Online ahead of print
Epub:
Yes
Abstract:
Photoreceptors of the vertebrate neural retina are originated from the neuroepithelium, and like other neurons, must undergo...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Aparicio G, Rodao M, Badano JL, Zolessi FR. Photoreceptor progenitor dynamics in the zebrafish embryo retina and its modulation by primary cilia and N-cadherin. Int J Dev Biol. 2020 Aug 25. doi: 10.1387/ijdb.200113fz. Online ahead of print.

Tek/Tie2 is not required for cardiovascular development in zebrafish

Authors:
Jiang Z, Carlantoni C, Allanki S, Ebersberger I, Stainier DYR
Citation:
Development. 2020 Sep 14:dev.193029. doi: 10.1242/dev.193029. Online ahead of print
Epub:
Not Epub
Abstract:
Angiopoietin/TIE signalling plays a major role in blood and lymphatic vessel development. In mouse, Tek/Tie2 mutants die...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jiang Z, Carlantoni C, Allanki S, Ebersberger I, Stainier DYR. Tek/Tie2 is not required for cardiovascular development in zebrafish. Development. 2020 Sep 14:dev.193029. doi: 10.1242/dev.193029. Online ahead of print.

IL-10 production by ILC2s requires Blimp-1 and cMaf, modulates cellular metabolism and ameliorates airway hyperreactivity

Authors:
Howard E, Lewis G, Galle-Treger L, Hurrell BP, Helou DG, Shafiei-Jahani P, Painter J, Muench GA, Soroosh P, Akbari O
Citation:
J Allergy Clin Immunol. 2020 Sep 6:S0091-6749(20)31234-3. doi: 10.1016/j.jaci.2020.08.024. Online ahead of print
Epub:
Yes
Abstract:
Background: ILC2s are the dominant innate lymphoid cell population in the lungs at steady state and their release of type 2...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: Murine Group 2 Innate Lymphoid Cells ILC2
Citation Extract:
Howard E, Lewis G, Galle-Treger L, Hurrell BP, Helou DG, Shafiei-Jahani P, Painter J, Muench GA, Soroosh P, Akbari O. IL-10 production by ILC2s requires Blimp-1 and cMaf, modulates cellular metabolism and ameliorates airway hyperreactivity. J Allergy Clin Immunol. 2020 Sep 6:S0091-6749(20)31234-3. doi: 10.1016/j.jaci.2020.08.024. Online ahead of print.

NEAT1 polyA-modulating antisense oligonucleotides reveal opposing functions for both long non-coding RNA isoforms in neuroblastoma

Authors:
Naveed A, Cooper JA, Li R, Hubbard A, Chen J, Liu T, Wilton SD, Fletcher S, Fox AH
Citation:
Cell Mol Life Sci. 2020 Sep 10. doi: 10.1007/s00018-020-03632-6. Online ahead of print
Epub:
Yes
Abstract:
Many long non-coding RNAs (lncRNA) are highly dysregulated in cancer and are emerging as therapeutic targets. One example is...
Delivery Method:
DNA leash and Lipofectamine
Organism or Cell Type:
cell culture: neuroblastoma lines: KELLY, BE2C & SK-N-AS
Citation Extract:
Naveed A, Cooper JA, Li R, Hubbard A, Chen J, Liu T, Wilton SD, Fletcher S, Fox AH. NEAT1 polyA-modulating antisense oligonucleotides reveal opposing functions for both long non-coding RNA isoforms in neuroblastoma. Cell Mol Life Sci. 2020 Sep 10. doi: 10.1007/s00018-020-03632-6. Online ahead of print.

A 12-lipoxygenase-Gpr31 signaling axis is required for pancreatic organogenesis in the zebrafish

Authors:
Hernandez-Perez M, Kulkarni A, Samala N, Sorrell C, El K, Haider I, Mukhtar Aleem A, Holman TR, Rai G, Tersey SA, Mirmira RG, Anderson RM
Citation:
FASEB J. 2020 Sep 12. doi: 10.1096/fj.201902308RR. Online ahead of print.
Epub:
Yes
Abstract:
12-Lipoxygenase (12-LOX) is a key enzyme in arachidonic acid metabolism, and alongside its major product, 12-HETE, plays a key...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hernandez-Perez M, Kulkarni A, Samala N, Sorrell C, El K, Haider I, Mukhtar Aleem A, Holman TR, Rai G, Tersey SA, Mirmira RG, Anderson RM. A 12-lipoxygenase-Gpr31 signaling axis is required for pancreatic organogenesis in the zebrafish. FASEB J. 2020 Sep 12. doi: 10.1096/fj.201902308RR. Online ahead of print..

Using an aquatic model, Xenopus laevis, to uncover the role of chromodomain 1 in craniofacial disorders

Authors:
Wyatt BH, Raymond TO, Lansdon LA, Darbro BW, Murray JC, Manak JR, Dickinson AJG
Citation:
Genesis. 2020 Sep 11:e23394. doi: 10.1002/dvg.23394. Online ahead of print
Epub:
Yes
Abstract:
The chromodomain family member chromodomain 1 (CHD1) has been shown to have numerous critical molecular functions including...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Wyatt BH, Raymond TO, Lansdon LA, Darbro BW, Murray JC, Manak JR, Dickinson AJG. Using an aquatic model, Xenopus laevis, to uncover the role of chromodomain 1 in craniofacial disorders. Genesis. 2020 Sep 11:e23394. doi: 10.1002/dvg.23394. Online ahead of print.

Esco2 and Cohesin Regulate CRL4 Ubiquitin Ligase ddb1 Expression and Thalidomide Teratogenicity

Authors:
Sanchez AC, Thren ED, Iovine MK, Skibbens RV
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.09.02.280149
Epub:
Not Epub
Abstract:
Cornelia de Lange syndrome (CdLS) and Roberts syndrome (RBS) are severe developmental maladies that arise from mutation of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sanchez AC, Thren ED, Iovine MK, Skibbens RV. Esco2 and Cohesin Regulate CRL4 Ubiquitin Ligase ddb1 Expression and Thalidomide Teratogenicity. bioRxiv. 2020;[preprint] doi:10.1101/2020.09.02.280149.

Twinfilin1 controls lamellipodial protrusive activity and actin turnover during vertebrate gastrulation

Authors:
Devitt CC, Lee C, Cox RM, Papoulas O, Alvarado J, Marcotte EM, Wallingford JB
Citation:
bioRxiv. 2020;[preprint] doi:/10.1101/2020.09.03.281659
Epub:
Not Epub
Abstract:
The dynamic control of the actin cytoskeleton is a key aspect of essentially all animal cell movements. Experiments in single...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Devitt CC, Lee C, Cox RM, Papoulas O, Alvarado J, Marcotte EM, Wallingford JB. Twinfilin1 controls lamellipodial protrusive activity and actin turnover during vertebrate gastrulation. bioRxiv. 2020;[preprint] doi:/10.1101/2020.09.03.281659.

A direct link of the Mos-MAPK pathway to Erp1/Emi2 in meiotic arrest of Xenopus laevis eggs

Authors:
Inoue D, Ohe M, Kanemori Y, Nobui T, Sagata N
Citation:
Nature. 2007 Apr 26;446(7139):1100-4. doi: 10.1038/nature05688. Epub 2007 Apr 4
Epub:
Not Epub
Abstract:
In vertebrates, unfertilized eggs (or mature oocytes) are arrested at metaphase of meiosis II by a cytoplasmic activity called...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Inoue D, Ohe M, Kanemori Y, Nobui T, Sagata N. A direct link of the Mos-MAPK pathway to Erp1/Emi2 in meiotic arrest of Xenopus laevis eggs. Nature. 2007 Apr 26;446(7139):1100-4. doi: 10.1038/nature05688. Epub 2007 Apr 4.

Critical Role for Cold Shock Protein YB-1 in Cytokinesis

Authors:
Mehta S, Algie M, Al-Jabry T, McKinney C, Kannan S, Verma CS, Ma W, Zhang J, Bartolec TK, Masamsetti VP, Parker K, Henderson L, Gould ML, Bhatia P, Harfoot R, Chircop M, Kleffmann T, Cohen SB, Woolley AG, Cesare AJ, Braithwaite A
Citation:
Cancers (Basel). 2020 Sep 1;12(9):E2473. doi: 10.3390/cancers12092473
Epub:
Not Epub
Abstract:
High levels of the cold shock protein Y-box-binding protein-1, YB-1, are tightly correlated with increased cell proliferation...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mehta S, Algie M, Al-Jabry T, McKinney C, Kannan S, Verma CS, Ma W, Zhang J, Bartolec TK, Masamsetti VP, Parker K, Henderson L, Gould ML, Bhatia P, Harfoot R, Chircop M, Kleffmann T, Cohen SB, Woolley AG, Cesare AJ, Braithwaite A. Critical Role for Cold Shock Protein YB-1 in Cytokinesis. Cancers (Basel). 2020 Sep 1;12(9):E2473. doi: 10.3390/cancers12092473.

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