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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

xCyp26c Induced by Inhibition of BMP Signaling Is Involved in Anterior-Posterior Neural Patterning of Xenopus laevis

Authors:
Yu SB, Umair Z, Kumar S, Lee U, Lee SH, Kim JI, Kim S, Park JB, Lee JY, Kim J
Citation:
Mol Cells. 2016 Feb 29. doi: 10.14348/molcells.2016.0006. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Vertebrate neurogenesis requires inhibition of endogenous bone morphogenetic protein (BMP) signals in the ectoderm. Blocking of...
Link:
http://www.molcells.org/journal/view.html?doi=10.14348/molcells.2016.0006&
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yu SB, Umair Z, Kumar S, Lee U, Lee SH, Kim JI, Kim S, Park JB, Lee JY, Kim J. xCyp26c Induced by Inhibition of BMP Signaling Is Involved in Anterior-Posterior Neural Patterning of Xenopus laevis. Mol Cells. 2016 Feb 29. doi: 10.14348/molcells.2016.0006. [Epub ahead of print].

DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia

Authors:
Li Y, Yagi H, Onuoha EO, Damerla RR, Francis R, Furutani Y, Tariq M, King SM, Hendricks G, Cui C, Saydmohammed M, Lee DM, Zahid M, Sami I, Leatherbury L, Pazour GJ, Ware SM, Nakanishi T, Goldmuntz E, Tsang M, Lo CW
Citation:
PLoS Genet. 2016 Feb 26;12(2):e1005821. doi: 10.1371/journal.pgen.1005821. eCollection 2016 Feb
Epub:
Not Epub
Abstract:
Heterotaxy, a birth defect involving left-right patterning defects, and primary ciliary dyskinesia (PCD), a sinopulmonary...
Link:
http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1005821
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li Y, Yagi H, Onuoha EO, Damerla RR, Francis R, Furutani Y, Tariq M, King SM, Hendricks G, Cui C, Saydmohammed M, Lee DM, Zahid M, Sami I, Leatherbury L, Pazour GJ, Ware SM, Nakanishi T, Goldmuntz E, Tsang M, Lo CW. DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia. PLoS Genet. 2016 Feb 26;12(2):e1005821. doi: 10.1371/journal.pgen.1005821. eCollection 2016 Feb.

Biological outcome and mapping of total factor cascades in response to HIF induction during regenerative angiogenesis

Authors:
Khatib A-M, Lahlil R, Hagedorn M, Delomenie C, Christophe O, Denis C, Siegfried G
Citation:
Oncotarget. 2016;[Epub ahead of print] doi:10.18632/oncotarget.7728
Epub:
Yes
Abstract:
Hypoxia Inducible Factor (HIF) is the main transcription factor that mediates cell response to hypoxia. Howeverthe complex...
Link:
http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path[]=7728&path[]=22486
Delivery Method:
injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Khatib A-M, Lahlil R, Hagedorn M, Delomenie C, Christophe O, Denis C, Siegfried G. Biological outcome and mapping of total factor cascades in response to HIF induction during regenerative angiogenesis. Oncotarget. 2016;[Epub ahead of print] doi:10.18632/oncotarget.7728.

Integration of Multiplexed Microfluidic Electrokinetic Concentrators with a Morpholino Microarray via Reversible Surface Bonding for Enhanced DNA Hybridization

Authors:
Martins D, Wei X, Levicky R, Song Y-AR
Citation:
Anal Chem. 2016;[Epub ahead of print] doi:10.1021/acs.analchem.5b03875
Epub:
Not Epub
Abstract:
We describe a microfluidic concentration device to accelerate the surface hybridization reaction between DNA and morpholinos (...
Link:
http://pubs.acs.org/doi/abs/10.1021/acs.analchem.5b03875
Citation Extract:
Martins D, Wei X, Levicky R, Song Y-AR. Integration of Multiplexed Microfluidic Electrokinetic Concentrators with a Morpholino Microarray via Reversible Surface Bonding for Enhanced DNA Hybridization. Anal Chem. 2016;[Epub ahead of print] doi:10.1021/acs.analchem.5b03875.

Zygotic LvBMP5-8 is required for skeletal patterning and for left-right but not dorsal-ventral specification in the sea urchin embryo

Authors:
Piacentino ML, Chung O, Ramachandran J, Zuch DT, Yu J, Conaway EA, Reyna AE, Bradham CA
Citation:
Dev Biol. 2016 Feb 20. pii: S0012-1606(15)30209-8. doi: 10.1016/j.ydbio.2016.02.015. [Epub ahead of print]
Epub:
Yes
Abstract:
Skeletal patterning in the sea urchin embryo requires coordinated signaling between the pattern-dictating ectoderm and the...
Link:
http://www.sciencedirect.com/science/journal/aip/00121606
Organism or Cell Type:
sea urchin
Citation Extract:
Piacentino ML, Chung O, Ramachandran J, Zuch DT, Yu J, Conaway EA, Reyna AE, Bradham CA. Zygotic LvBMP5-8 is required for skeletal patterning and for left-right but not dorsal-ventral specification in the sea urchin embryo. Dev Biol. 2016 Feb 20. pii: S0012-1606(15)30209-8. doi: 10.1016/j.ydbio.2016.02.015. [Epub ahead of print].

Mutations in Subunits of the Activating Signal Cointegrator 1 Complex Are Associated with Prenatal Spinal Muscular Atrophy and Congenital Bone Fractures

Authors:
Knierim E, Hirata H, Wolf NI, Morales-Gonzalez S, Schottmann G, Tanaka Y, Rudnik-Schöneborn S, Orgeur M, Zerres K, Vogt S, van Riesen A, Gill E, Seifert F, Zwirner A, Kirschner J, Goebel HH, Hübner C, Stricker S, Meierhofer D, Stenzel W, Schuelke M
Citation:
Am J Hum Genet. 2016;[Epub ahead of print] doi:10.1016/j.ajhg.2016.01.006
Epub:
Yes
Abstract:
Transcriptional signal cointegrators associate with transcription factors or nuclear receptors and coregulate tissue-specific...
Link:
http://www.cell.com/ajhg/abstract/S0002-9297%2816%2900012-4
Organism or Cell Type:
zebrafish
Citation Extract:
Knierim E, Hirata H, Wolf NI, Morales-Gonzalez S, Schottmann G, Tanaka Y, Rudnik-Schöneborn S, Orgeur M, Zerres K, Vogt S, van Riesen A, Gill E, Seifert F, Zwirner A, Kirschner J, Goebel HH, Hübner C, Stricker S, Meierhofer D, Stenzel W, Schuelke M. Mutations in Subunits of the Activating Signal Cointegrator 1 Complex Are Associated with Prenatal Spinal Muscular Atrophy and Congenital Bone Fractures. Am J Hum Genet. 2016;[Epub ahead of print] doi:10.1016/j.ajhg.2016.01.006.

Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis

Authors:
Raman M, Sergeev M, Garnaas M, Lydeard JR, Huttlin EL, Goessling W, Shah JV, Harper JW
Citation:
Nat Cell Biol. 2015 Oct;17(10):1356-69. doi: 10.1038/ncb3238. Epub 2015 Sep 21
Epub:
Not Epub
Abstract:
The AAA-ATPase VCP (also known as p97 or CDC48) uses ATP hydrolysis to 'segregate' ubiquitylated proteins from their...
Link:
http://www.nature.com/ncb/journal/v17/n10/full/ncb3238.html
Organism or Cell Type:
zebrafish
Citation Extract:
Raman M, Sergeev M, Garnaas M, Lydeard JR, Huttlin EL, Goessling W, Shah JV, Harper JW. Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis. Nat Cell Biol. 2015 Oct;17(10):1356-69. doi: 10.1038/ncb3238. Epub 2015 Sep 21.

Reticular dysgenesis-associated AK2 protects hematopoietic stem and progenitor cell development from oxidative stress

Authors:
Rissone A, Weinacht KG, la Marca G, Bishop K, Giocaliere E, Jagadeesh J, Felgentreff K, Dobbs K, Al-Herz W, Jones M, Chandrasekharappa S, Kirby M, Wincovitch S, Simon KL, Itan Y, DeVine A, Schlaeger T, Schambach A, Sood R, Notarangelo LD, Candotti F
Citation:
J Exp Med. 2015 Jul 27;212(8):1185-202. doi: 10.1084/jem.20141286. Epub 2015 Jul 6
Epub:
Not Epub
Abstract:
Adenylate kinases (AKs) are phosphotransferases that regulate the cellular adenine nucleotide composition and play a critical...
Link:
http://jem.rupress.org/content/212/8/1185.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rissone A, Weinacht KG, la Marca G, Bishop K, Giocaliere E, Jagadeesh J, Felgentreff K, Dobbs K, Al-Herz W, Jones M, Chandrasekharappa S, Kirby M, Wincovitch S, Simon KL, Itan Y, DeVine A, Schlaeger T, Schambach A, Sood R, Notarangelo LD, Candotti F. Reticular dysgenesis-associated AK2 protects hematopoietic stem and progenitor cell development from oxidative stress. J Exp Med. 2015 Jul 27;212(8):1185-202. doi: 10.1084/jem.20141286. Epub 2015 Jul 6.

DNA methylation analysis of Homeobox genes implicates HOXB7 hypomethylation as risk factor for neural tube defects

Authors:
Rochtus A, Izzi B, Vangeel E, Louwette S, Wittevrongel C, Lambrechts D, Moreau Y, Winand R, Verpoorten C, Jansen K, Van Geet C, Freson K
Citation:
Epigenetics. 2015;10(1):92-101. doi: 10.1080/15592294.2014.998531. Epub 2015 Jan 29
Epub:
Not Epub
Abstract:
Neural tube defects (NTDs) are common birth defects of complex etiology. Though family- and population-based studies have...
Link:
http://www.tandfonline.com/doi/full/10.1080/15592294.2014.998531
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rochtus A, Izzi B, Vangeel E, Louwette S, Wittevrongel C, Lambrechts D, Moreau Y, Winand R, Verpoorten C, Jansen K, Van Geet C, Freson K. DNA methylation analysis of Homeobox genes implicates HOXB7 hypomethylation as risk factor for neural tube defects. Epigenetics. 2015;10(1):92-101. doi: 10.1080/15592294.2014.998531. Epub 2015 Jan 29.

Analysis of mucolipidosis II/III GNPTAB missense mutations identifies domains of UDP-GlcNAc:lysosomal enzyme GlcNAc-1-phosphotransferase involved in catalytic function and lysosomal enzyme recognition

Authors:
Qian Y, van Meel E, Flanagan-Steet H, Yox A, Steet R, Kornfeld S
Citation:
J Biol Chem. 2015 Jan 30;290(5):3045-56. doi: 10.1074/jbc.M114.612507. Epub 2014 Dec 11
Epub:
Not Epub
Abstract:
UDP-GlcNAc:lysosomal enzyme GlcNAc-1-phosphotransferase tags newly synthesized lysosomal enzymes with mannose 6-phosphate...
Link:
http://www.jbc.org/content/290/5/3045.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Qian Y, van Meel E, Flanagan-Steet H, Yox A, Steet R, Kornfeld S. Analysis of mucolipidosis II/III GNPTAB missense mutations identifies domains of UDP-GlcNAc:lysosomal enzyme GlcNAc-1-phosphotransferase involved in catalytic function and lysosomal enzyme recognition. J Biol Chem. 2015 Jan 30;290(5):3045-56. doi: 10.1074/jbc.M114.612507. Epub 2014 Dec 11.

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