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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Haploinsufficiency of RCBTB1 is Associated with Coats Disease and Familial Exudative Vitreoretinopathy
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Citation:
Hum Mol Genet. 2016 Feb 11. pii: ddw041. [Epub ahead of print] Epub:
Yes Abstract:
Familial exudative vitreoretinopathy (FEVR) belongs to a group of genetically and clinically heterogeneous disorders in retinal... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wu JH, Liu JH, Ko YC, Wang CT, Chung YC, Chu KC, Liu TT, Chao HM, Jiang YJ, Chen SJ, Chung MY. Haploinsufficiency of RCBTB1 is Associated with Coats Disease and Familial Exudative Vitreoretinopathy. Hum Mol Genet. 2016 Feb 11. pii: ddw041. [Epub ahead of print]. |
A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies
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Citation:
Sci Transl Med. 2016;8(328):328ra30 doi:10.1126/scitranslmed.aad7666 Epub:
Not Epub Abstract:
The Src family kinase (SFK) member SRC is a major target in drug development because it is activated in many human cancers, yet... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Turro E, Greene D, Wijgaerts A, Thys C, Lentaigne C, Bariana TK, Westbury SK, Kelly AM, Selleslag D, Stephens JC, Papadia S, Simeoni I, Penkett CJ, Ashford S, Attwood A, Austin S, Bakchoul T, Collins P, Deevi SVV, Favier R, Kostadima M, Lambert MP, Mathias M, Millar CM, Peerlinck K, Perry DJ, Schulman S, Whitehorn D, Wittevrongel C, BRIDGE-BPD Consortium, De Maeyer M, Rendon A, Gomez K, Erber WN, Mumford AD, Nurden P, Stirrups K, Bradley JR, Raymond FL, Laffan MA, Van Geet C, Richardson S, Freson K, Ouwehand WH. A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies. Sci Transl Med. 2016;8(328):328ra30 doi:10.1126/scitranslmed.aad7666. |
Inactivation of 3-hydroxybutyrate dehydrogenase 2 delays zebrafish erythroid maturation by conferring premature mitophagy
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Citation:
Proc Natl Acad Sci U S A. 2016 Feb 29. pii: 201600077. [Epub ahead of print] Epub:
Yes Abstract:
Mitochondria are the site of iron utilization, wherein imported iron is incorporated into heme or iron-sulfur clusters.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Davuluri G, Song P, Liu Z, Wald D, Sakaguchi TF, Green MR, Devireddy L. Inactivation of 3-hydroxybutyrate dehydrogenase 2 delays zebrafish erythroid maturation by conferring premature mitophagy. Proc Natl Acad Sci U S A. 2016 Feb 29. pii: 201600077. [Epub ahead of print]. |
Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs
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Citation:
Toxicol Sci. 2015 Oct;147(2):397-411. doi: 10.1093/toxsci/kfv139. Epub 2015 Jul 3 Epub:
Not Epub Abstract:
Polycyclic aromatic hydrocarbons (PAHs) are priority environmental contaminants that exhibit mutagenic, carcinogenic,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Goodale BC, La Du J, Tilton SC, Sullivan CM, Bisson WH, Waters KM, Tanguay RL. Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs. Toxicol Sci. 2015 Oct;147(2):397-411. doi: 10.1093/toxsci/kfv139. Epub 2015 Jul 3. |
Active DNA demethylation at enhancers during the vertebrate phylotypic period
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Citation:
Nat Genet. 2016 Feb 29. doi: 10.1038/ng.3522. [Epub ahead of print] Epub:
Yes Abstract:
The vertebrate body plan and organs are shaped during a conserved embryonic phase called the phylotypic stage. However, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bogdanović O, Smits AH, de la Calle Mustienes E, Tena JJ, Ford E, Williams R, Senanayake U, Schultz MD, Hontelez S, van Kruijsbergen I, Rayon T, Gnerlich F, Carell T, Veenstra GJ, Manzanares M, Sauka-Spengler T, Ecker JR, Vermeulen M, Gómez-Skarmeta JL, Lister R. Active DNA demethylation at enhancers during the vertebrate phylotypic period. Nat Genet. 2016 Feb 29. doi: 10.1038/ng.3522. [Epub ahead of print]. |
Slow Muscle Precursors Lay Down a Collagen XV Matrix Fingerprint to Guide Motor Axon Navigation
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Citation:
J Neurosci. 2016;36(9):2663-76. doi:10.1523/JNEUROSCI.2847-15.2016 Epub:
Not Epub Abstract:
The extracellular matrix (ECM) provides local positional information to guide motoneuron axons toward their muscle target.... Organism or Cell Type:
zebrafish Citation Extract: Guillon E, Bretaud S, Ruggiero F. Slow Muscle Precursors Lay Down a Collagen XV Matrix Fingerprint to Guide Motor Axon Navigation. J Neurosci. 2016;36(9):2663-76. doi:10.1523/JNEUROSCI.2847-15.2016. |
MARCKS-like protein is an initiating molecule in axolotl appendage regeneration
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Citation:
Nature. 2016;[Epub ahead of print] doi:10.1038/nature16974 Epub:
Yes Abstract:
Identifying key molecules that launch regeneration has been a long-sought goal. Multiple regenerative animals show an initial... Delivery Method:
electroporation, injection then electroporation Organism or Cell Type:
cell culture: A1 myoblasts, axolotl Citation Extract: Sugiura T, Wang H, Barsacchi R, Simon A, Tanaka EM. MARCKS-like protein is an initiating molecule in axolotl appendage regeneration. Nature. 2016;[Epub ahead of print] doi:10.1038/nature16974. |
ES1 is a mitochondrial enlarging factor contributing to form mega-mitochondria in zebrafish cones
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Citation:
Sci Rep. 2016 Mar 1;6:22360. doi: 10.1038/srep22360 Epub:
Not Epub Abstract:
Total mass of mitochondria increases during cell proliferation and differentiation through mitochondrial biogenesis, which... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Masuda T, Wada Y, Kawamura S. ES1 is a mitochondrial enlarging factor contributing to form mega-mitochondria in zebrafish cones. Sci Rep. 2016 Mar 1;6:22360. doi: 10.1038/srep22360. |
Assessing Smoothened-mediated Hedgehog signaling in zebrafish
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Citation:
Methods Cell Biol. 2016;132:147-64. doi: 10.1016/bs.mcb.2015.10.001. Epub 2015 Dec 24 Epub:
Not Epub Abstract:
Smoothened belongs to the class of atypical G protein-coupled receptors and serves as the transducing molecule in Hedgehog (Hh... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tena TC, Philipp M. Assessing Smoothened-mediated Hedgehog signaling in zebrafish. Methods Cell Biol. 2016;132:147-64. doi: 10.1016/bs.mcb.2015.10.001. Epub 2015 Dec 24. |
Knockdown of zebrafish YY1a can downregulate the phosphatidylserine (PS) receptor expression, leading to induce the abnormal brain and heart development
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Citation:
J Biomed Sci. 2016 Feb 29;23(1):31. doi: 10.1186/s12929-016-0248-1 Epub:
Not Epub Abstract:
BACKGROUND: Yin Yang 1 (YY1) is a ubiquitously expressed GLI-Kruppel zinc finger-containing transcriptional regulator. YY1... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Shiu WL, Huang KR, Hung JC, Wu JL, Hong JR. Knockdown of zebrafish YY1a can downregulate the phosphatidylserine (PS) receptor expression, leading to induce the abnormal brain and heart development. J Biomed Sci. 2016 Feb 29;23(1):31. doi: 10.1186/s12929-016-0248-1. |