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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Contractile and hemodynamic forces coordinate Notch1b-mediated outflow tract valve formation
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Citation:
JCI Insight. 2019;[in-press preview] doi:10.1172/jci.insight.124460 Epub:
Yes Abstract:
Biomechanical forces and endothelial-to-mesenchymal transition (EndoMT) are known to mediate valvulogenesis. However, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hsu JJ, Vedula V, Baek KI, Chen C, Chen J, Chou MI, Lam J, Subhedar S, Wang J, Ding Y, Chang C-C, Lee J, Demer LL, Tintut Y, Marsden AL, Hsiai TK. Contractile and hemodynamic forces coordinate Notch1b-mediated outflow tract valve formation. JCI Insight. 2019;[in-press preview] doi:10.1172/jci.insight.124460. |
The voltage sensing phosphatase (VSP) localizes to the apical membrane of kidney tubule epithelial cells
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Citation:
PLoS ONE. 2019;14(4):e0209056. doi:10.1371/journal.pone.0209056 Epub:
Not Epub Abstract:
Voltage-sensing phosphatases (VSPs) are transmembrane proteins that couple changes in membrane potential to hydrolysis of... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Ratzan W, Rayaprolu V, Killian SE, Bradley R, Kohout SC. The voltage sensing phosphatase (VSP) localizes to the apical membrane of kidney tubule epithelial cells. PLoS ONE. 2019;14(4):e0209056. doi:10.1371/journal.pone.0209056. |
Sec14l3 potentiates VEGFR2 signaling to regulate zebrafish vasculogenesis
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Citation:
Nat Comm. 2019;10(1):1606 doi:10.1038/s41467-019-09604-0 Epub:
Not Epub Abstract:
Vascular endothelial growth factor (VEGF) regulates vasculogenesis by using its tyrosine kinase receptors. However, little is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gong B, Li Z, Xiao W, Li G, Ding S, Meng A, Jia S. Sec14l3 potentiates VEGFR2 signaling to regulate zebrafish vasculogenesis. Nat Comm. 2019;10(1):1606 doi:10.1038/s41467-019-09604-0. |
Clec14a genetically interacts with Etv2 and Vegf signaling during vasculogenesis and angiogenesis in zebrafish
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Citation:
BMC Dev Biol. 2019 Apr 5;19(1):6. doi: 10.1186/s12861-019-0188-6 Epub:
Not Epub Abstract:
BACKGROUND: C-lectin family 14 Member A (Clec14a) is a transmembrane protein specifically expressed in vascular endothelial... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pociute K, Schumacher JA, Sumanas S. Clec14a genetically interacts with Etv2 and Vegf signaling during vasculogenesis and angiogenesis in zebrafish. BMC Dev Biol. 2019 Apr 5;19(1):6. doi: 10.1186/s12861-019-0188-6. |
Analysis of microRNA functions
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Citation:
Methods Cell Biol. 2019;151:323-334. doi: 10.1016/bs.mcb.2018.10.005. Epub 2018 Dec 11 Epub:
Not Epub Abstract:
MicroRNAs (miRNAs) are small non-coding RNAs that repress the translation and reduce the stability of target mRNAs in animal... Delivery Method:
microinjection Organism or Cell Type:
sea urchin Citation Extract: Remsburg C, Konrad K, Sampilo NF, Song JL. Analysis of microRNA functions. Methods Cell Biol. 2019;151:323-334. doi: 10.1016/bs.mcb.2018.10.005. Epub 2018 Dec 11. |
Loss-of-function approaches in comparative physiology: is there a future for knockdown experiments in the era of genome editing?
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Citation:
J Exp Biol. 2019 Apr 4;222(Pt 7). pii: jeb175737. doi: 10.1242/jeb.175737. Review Epub:
Not Epub Abstract:
Loss-of-function technologies, such as morpholino- and RNAi-mediated gene knockdown, and TALEN- and CRISPR/Cas9-mediated gene... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zimmer AM, Pan YK, Chandrapalan T, Kwong RWM, Perry SF. Loss-of-function approaches in comparative physiology: is there a future for knockdown experiments in the era of genome editing?. J Exp Biol. 2019 Apr 4;222(Pt 7). pii: jeb175737. doi: 10.1242/jeb.175737. Review. |
Prostaglandin signaling regulates renal multiciliated cell specification and maturation
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Citation:
Proc Nat Acad Sci USA. 2019;[Epub ahead of print] doi:10.1073/pnas.1813492116 Epub:
Yes Abstract:
Multiciliated cells (MCCs) are specialized epithelia with apical bundles of motile cilia that direct fluid flow. MCC... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Marra AN, Adeeb BD, Chambers BE, Drummond BE, Ulrich M, Addiego A, Springer M, Poureetezadi SJ, Chambers JM, Ronshaugen M, Wingert RA. Prostaglandin signaling regulates renal multiciliated cell specification and maturation. Proc Nat Acad Sci USA. 2019;[Epub ahead of print] doi:10.1073/pnas.1813492116. |
GPCR-independent activation of G proteins promotes apical cell constriction in vivo
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Citation:
J Cell Biol. 2019;[Epub ahead of print] doi:10.1083/jcb.201811174 Epub:
Yes Abstract:
Heterotrimeric G proteins are signaling switches that control organismal morphogenesis across metazoans. In invertebrates,... Organism or Cell Type:
Xenopus laevis Citation Extract: Marivin A, Morozova V, Walawalkar I, Leyme A, Kretov DA, Cifuentes D, Dominguez I, Garcia-Marcos M. GPCR-independent activation of G proteins promotes apical cell constriction in vivo. J Cell Biol. 2019;[Epub ahead of print] doi:10.1083/jcb.201811174. |
Extracellular Matrix Signaling Through β3 Integrin Mediates Cocaine Cue-induced Transient Synaptic Plasticity and Relapse
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Citation:
Biol Psych. 2019;[Epub ahead of print] doi:10.1016/j.biopsych.2019.03.982 Epub:
Yes Abstract:
Background: Cue-induced relapse to drug use is a primary symptom of cocaine addiction. Cue-induced transient excitatory... Organism or Cell Type:
rats Citation Extract: Garcia-Keller C, Neuhofer D, Bobadilla A-C, Spencer S, Chioma V, Monforton C, Kalivas PW. Extracellular Matrix Signaling Through β3 Integrin Mediates Cocaine Cue-induced Transient Synaptic Plasticity and Relapse. Biol Psych. 2019;[Epub ahead of print] doi:10.1016/j.biopsych.2019.03.982. |
A novel evolutionary conserved mechanism of RNA stability regulates synexpression of primordial germ cell-specific genes prior to the sex-determination stage in medaka
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Citation:
PLoS Biol. 2019;17(4):e3000185. https://doi.org/10.1371/journal.pbio.3000185 Epub:
Not Epub Abstract:
Dmrt1 is a highly conserved transcription factor, which is critically involved in regulation of gonad development of... Delivery Method:
microinjection Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Herpin A, Schmidt C, Kneitz S, Gobé C, Regensburger M, Le Cam A, Montfort J, Adolfi MC, Lillesaar C, Wilhelm D, Kraeussling M, Mourot B, Porcon B, Pannetier M, Pailhoux E, Ettwiller L, Dolle D, Guiguen Y, Schartl M. A novel evolutionary conserved mechanism of RNA stability regulates synexpression of primordial germ cell-specific genes prior to the sex-determination stage in medaka. PLoS Biol. 2019;17(4):e3000185. https://doi.org/10.1371/journal.pbio.3000185. |