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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
QDPR homologues in Danio rerio regulate melanin synthesis, early gliogenesis, and glutamine homeostasis
Citation:
PLoS ONE. 2019;14(4):e0215162. doi:10.1371/journal.pone.0215162 Epub:
Not Epub Abstract:
Dihydropteridine reductase (QDPR) catalyzes the recycling of tetrahydrobiopterin (BH4), a cofactor in dopamine, serotonin, and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Breuer M, Guglielmi L, Zielonka M, Hemberger V, Kölker S, Okun JG, Hoffmann GF, Carl M, Sauer SW, Opladen T. QDPR homologues in Danio rerio regulate melanin synthesis, early gliogenesis, and glutamine homeostasis. PLoS ONE. 2019;14(4):e0215162. doi:10.1371/journal.pone.0215162. |
Visualizing flow in an intact CSF network using optical coherence tomography: implications for human congenital hydrocephalus
Citation:
Sci Rep. 2019;9(1):6196. doi:10.1038/s41598-019-42549-4 Epub:
Not Epub Abstract:
Cerebrospinal fluid (CSF) flow in the brain ventricles is critical for brain development. Altered CSF flow dynamics have been... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Date P, Ackermann P, Furey C, Fink IB, Jonas S, Khokha MK, Kahle KT, Deniz E. Visualizing flow in an intact CSF network using optical coherence tomography: implications for human congenital hydrocephalus. Sci Rep. 2019;9(1):6196. doi:10.1038/s41598-019-42549-4. |
Mutations in ATP13A2 (PARK9) are associated with an amyotrophic lateral sclerosis-like phenotype, implicating this locus in further phenotypic expansion
Citation:
Hum Genomics. 2019;13:19. doi:10.1186/s40246-019-0203-9 Epub:
Not Epub Abstract:
Background: Amyotrophic lateral sclerosis [1] is a genetically heterogeneous neurodegenerative disorder, characterized by late-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Spataro R, Kousi M, Farhan SMK, Willer JR, Ross JP, Patrick A. Dion PA, Rouleau GA, Daly, Neale BM, La Bella V, Katsanis N. Mutations in ATP13A2 (PARK9) are associated with an amyotrophic lateral sclerosis-like phenotype, implicating this locus in further phenotypic expansion. Hum Genomics. 2019;13:19. doi:10.1186/s40246-019-0203-9. |
Horizontal Boundary Cells, a Special Group of Somitic Cells, Play Crucial Roles in the Formation of Dorsoventral Compartments in Teleost Somite
Citation:
Cell Rep. 2019;27(3):928-39.E4. doi:10.1016/j.celrep.2019.03.068 Epub:
Not Epub Abstract:
Establishment of robust gene expression boundary is crucial for creating elaborate morphology during development. However,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Abe K, Shimada A, Tayama S, Nishikawa H, Kaneko T, Tsuda S, Karaiwa A, Matsui T, Ishitani T, Takeda H. Horizontal Boundary Cells, a Special Group of Somitic Cells, Play Crucial Roles in the Formation of Dorsoventral Compartments in Teleost Somite. Cell Rep. 2019;27(3):928-39.E4. doi:10.1016/j.celrep.2019.03.068. |
The transmembrane protein Crb2a regulates cardiomyocyte apicobasal polarity and adhesion in zebrafish
Citation:
Development. 2019;[Epub ahead of print] doi:10.1242/dev.171207 Epub:
Yes Abstract:
Tissue morphogenesis requires changes in cell-cell adhesion as well as in cell shape and polarity. Cardiac trabeculation is a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jiménez-Amilburu V, Stainier DYR. The transmembrane protein Crb2a regulates cardiomyocyte apicobasal polarity and adhesion in zebrafish. Development. 2019;[Epub ahead of print] doi:10.1242/dev.171207. |
Wolf-Hirschhorn Syndrome-Associated Genes Are Enriched in Motile Neural Crest Cells and Affect Craniofacial Development in Xenopus laevis
Citation:
Front Physiol. 2019;10:431 doi:10.3389/fphys.2019.00431 Epub:
Not Epub Abstract:
Wolf-Hirschhorn Syndrome (WHS) is a human developmental disorder arising from a hemizygous perturbation, typically a... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Mills A, Bearce E, Cella R, Kim SW, Selig M, Lee S, Lowery LA. Wolf-Hirschhorn Syndrome-Associated Genes Are Enriched in Motile Neural Crest Cells and Affect Craniofacial Development in Xenopus laevis. Front Physiol. 2019;10:431 doi:10.3389/fphys.2019.00431. |
Mutations in the zebrafish hmgcs1 gene reveal a novel function for isoprenoids during red blood cell development
Citation:
Blood Adv. 2019;3:1244-54. doi:10.1182/bloodadvances.2018024539 Epub:
Not Epub Abstract:
Erythropoiesis is the process by which new red blood cells (RBCs) are formed and defects in this process can lead to anemia or... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hernandez JA, Castro VL, Reyes-Nava N, Montes LP, Quintana AM. Mutations in the zebrafish hmgcs1 gene reveal a novel function for isoprenoids during red blood cell development. Blood Adv. 2019;3:1244-54. doi:10.1182/bloodadvances.2018024539. |
Morphology and genome of a snailfish from the Mariana Trench provide insights into deep-sea adaptation
Citation:
Nature Ecol Evol. 2019;[Epub ahead of print] doi:10.1038/s41559-019-0864-8 Epub:
Yes Abstract:
It is largely unknown how living organisms - especially vertebrates - survive and thrive in the coldness, darkness and high... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang K, Shen Y, Yang Y, Gan X, Liu G, Hu K, Li Y, Gao Z, Zhu L, Yan G, He L, Shan X, Yang L, Lu S, Zeng H, Pan X, Liu C, Yuan Y, Feng C, Xu W, Zhu C, Xiao W, Dong Y, Wang W, Qiu Q, He S. Morphology and genome of a snailfish from the Mariana Trench provide insights into deep-sea adaptation. Nature Ecol Evol. 2019;[Epub ahead of print] doi:10.1038/s41559-019-0864-8. |
Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia
Citation:
Exp Eye Res. 2019;[Epub ahead of print] doi:10.1016/j.exer.2019.03.024 Epub:
Yes Abstract:
During an ENU (N-ethyl-N-nitrosourea) mutagenesis screen, we observed a dominant small-eye mutant mouse with viable homozygotes... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Vetrivel S, Tiso N, Kügler A, Irmler M, Horsch M, Beckers J, Hladik D, Giesert F, Gailus-Durner V, Fuchs H, Sabrautzki S, German Mouse Clinic, Helmholtz Zentrum München, German Research Center for Environmental Health GmbH, Adler T, Treise I, Busch DH, Aguilar-Pimentel A, Ollert M, Götz A, Amarie OV, Stoeger T, Schulz H, Becker L, Klopstock T, Schrewe A, Spielmann N, Bekeredjian R, Garrett L, Hölter SM, Zimprich A, Wurst W, Mayer-Kuckuk P, Hans W, Rozman J, Klingenspor M, Neff F, da Silva-Buttkus P, Calzada-Wack J, Rácz I, Zimmer A, Rathkolb B, Wolf E, Prehn C, Adamski J, Östereicher M, Miller G, Steinkamp R, Lengger C, Maier H, Stoeger C, Leuchtenberger S, Gailus-Durner V, Fuchs H, de Angelis MH, Graw J. Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia. Exp Eye Res. 2019;[Epub ahead of print] doi:10.1016/j.exer.2019.03.024. |
Genetic mosaics and time-lapse imaging identify functions of histone H3.3 residues in mouse oocytes and embryos
Citation:
Development. 2017 Feb 1;144(3):519-528. doi: 10.1242/dev.141390. Epub 2016 Dec 19 Epub:
Not Epub Abstract:
During development from oocyte to embryo, genetic programs in mouse germ cells are reshaped by chromatin remodeling to... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Zhou L, Baibakov B, Canagarajah B, Xiong B, Dean J. Genetic mosaics and time-lapse imaging identify functions of histone H3.3 residues in mouse oocytes and embryos. Development. 2017 Feb 1;144(3):519-528. doi: 10.1242/dev.141390. Epub 2016 Dec 19. |