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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Peroxisomes in zebrafish: distribution pattern and knockdown studies

Authors:
Krysko O, Stevens M, Langenberg T, Fransen M, Espeel M, Baes M
Citation:
Histochem Cell Biol. 2010 Jun 17. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Peroxisomes are organelles that are essential for normal development in men and mice. In order to explore whether zebrafish...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Krysko O, Stevens M, Langenberg T, Fransen M, Espeel M, Baes M. Peroxisomes in zebrafish: distribution pattern and knockdown studies. Histochem Cell Biol. 2010 Jun 17. [Epub ahead of print].

Positive and negative regulation of the transforming growth factor beta/activin target gene goosecoid by the TFII-I family of transcription factors.

Authors:
Ku M, Sokol SY, Wu J, Tussie-Luna MI, Roy AL, Hata A.
Citation:
Mol Cell Biol. 2005 Aug;25(16):7144-57.
Epub:
Not Epub
Abstract:
Goosecoid (Gsc) is a homeodomain-containing transcription factor present in a wide variety of vertebrate species and known to...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ku M, Sokol SY, Wu J, Tussie-Luna MI, Roy AL, Hata A.. Positive and negative regulation of the transforming growth factor beta/activin target gene goosecoid by the TFII-I family of transcription factors.. Mol Cell Biol. 2005 Aug;25(16):7144-57..

Progranulin is Neurotrophic In Vivo and Protects against a Mutant TDP-43 Induced Axonopathy

Authors:
Laird AS, Van Hoecke A, De Muynck L, Timmers M, Van Den Bosch L, Van Damme P, Robberecht W
Citation:
PLoS One. 2010 Oct 13;5(10). pii: e13368
Epub:
Not Epub
Abstract:
Mislocalization, aberrant processing and aggregation of TAR DNA-binding protein 43 (TDP-43) is found in the neurons affected by...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Laird AS, Van Hoecke A, De Muynck L, Timmers M, Van Den Bosch L, Van Damme P, Robberecht W. Progranulin is Neurotrophic In Vivo and Protects against a Mutant TDP-43 Induced Axonopathy. PLoS One. 2010 Oct 13;5(10). pii: e13368.

Provitamin A conversion to retinal via the beta,beta-carotene-15,15'-oxygenase (bcox) is essential for pattern formation and differentiation during zebrafish embryogenesis.

Authors:
Lampert JM, Holzschuh J, Hessel S, Driever W, Vogt K, Von Lintig J
Citation:
Development 2003 May;130(10):2173-86
Epub:
Not Epub
Abstract:
The egg yolk of vertebrates contains carotenoids, which account for its characteristic yellow color in some species. Such plant...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lampert JM, Holzschuh J, Hessel S, Driever W, Vogt K, Von Lintig J. Provitamin A conversion to retinal via the beta,beta-carotene-15,15'-oxygenase (bcox) is essential for pattern formation and differentiation during zebrafish embryogenesis.. Development 2003 May;130(10):2173-86.

Pygopus is required for embryonic brain patterning in Xenopus.

Authors:
Lake BB, Kao KR
Citation:
Dev Biol. 2003 Sep 1;261(1):132-48
Epub:
Not Epub
Abstract:
We have identified two Xenopus mRNAs that encode proteins homologous to a component of the Wnt/beta-catenin transcriptional...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Lake BB, Kao KR. Pygopus is required for embryonic brain patterning in Xenopus.. Dev Biol. 2003 Sep 1;261(1):132-48.

Pyrimidine morpholino oligonucleotides form a stable triple helix in the absence of magnesium ions

Authors:
Lacroix L, Arimondo PB, Takasugi M, Helene C, Mergny JL
Citation:
Biochem Biophys Res Commun 2000 Apr 13;270(2):363-9
Epub:
Not Epub
Abstract:
Oligonucleotides can be used as sequence-specific DNA ligands by forming a local triple helix. In order to form more stable...
Delivery Method:
not applicable
Organism or Cell Type:
not applicable
Citation Extract:
Lacroix L, Arimondo PB, Takasugi M, Helene C, Mergny JL. Pyrimidine morpholino oligonucleotides form a stable triple helix in the absence of magnesium ions. Biochem Biophys Res Commun 2000 Apr 13;270(2):363-9.

Rap1 promotes VEGFR2 activation and angiogenesis by a mechanism involving integrin αvβ3

Authors:
Lakshmikanthan S, Sobczak M, Chun C, Henschel A, Dargatz J, Ramchandran R, Chrzanowska-Wodnicka M
Citation:
Blood. 2011;[Epub ahead of print June 2, 2011] doi:10.1182/blood-2011-04-349282
Epub:
Not Epub
Abstract:
Vascular Endothelial Growth Factor (VEGF) acting through Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) on endothelial...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lakshmikanthan S, Sobczak M, Chun C, Henschel A, Dargatz J, Ramchandran R, Chrzanowska-Wodnicka M. Rap1 promotes VEGFR2 activation and angiogenesis by a mechanism involving integrin αvβ3. Blood. 2011;[Epub ahead of print June 2, 2011] doi:10.1182/blood-2011-04-349282.

Regional differences in BMP-dependence of dorsoventral patterning in the leech Helobdella

Authors:
Kuo DH, Shankland M, Weisblat DA
Citation:
Dev Biol. 2012 Aug 1;368(1):86-94. doi: 10.1016/j.ydbio.2012.05.021. Epub 2012 May 26
Epub:
Not Epub
Abstract:
In the leech Helobdella, the ectoderm exhibits a high degree of morphological homonomy between body segments, but pattern...
Delivery Method:
Microinjection
Organism or Cell Type:
Helobdella (leech)
Citation Extract:
Kuo DH, Shankland M, Weisblat DA. Regional differences in BMP-dependence of dorsoventral patterning in the leech Helobdella. Dev Biol. 2012 Aug 1;368(1):86-94. doi: 10.1016/j.ydbio.2012.05.021. Epub 2012 May 26.

Regulation of primitive hematopoiesis in zebrafish embryos by the death receptor gene

Authors:
Kwan TT, Liang R, Verfaillie CM, Ekker SC, Chan LC, Lin S, Leung AY
Citation:
Exp Hematol. 2006 Jan;34(1):27-34
Epub:
Not Epub
Abstract:
OBJECTIVE: We investigated the regulatory mechanism of primitive hematopoiesis in zebrafish (Danio rerio) embryos with...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kwan TT, Liang R, Verfaillie CM, Ekker SC, Chan LC, Lin S, Leung AY. Regulation of primitive hematopoiesis in zebrafish embryos by the death receptor gene. Exp Hematol. 2006 Jan;34(1):27-34.

Restoration of hemoglobin A synthesis in erythroid cells from peripheral blood of thalassemic patients

Authors:
Lacerra G, Sierakowska H, Carestia C, Fucharoen S, Summerton J, Weller D, Kole R
Citation:
Proc Natl Acad Sci U S A 2000 Aug 15;97(17):9591-6
Epub:
Not Epub
Abstract:
Mononuclear cells from peripheral blood of thalassemic patients were treated with morpholino oligonucleotides antisense to...
Delivery Method:
syringe loading
Organism or Cell Type:
cell culture: human mononuclear cells
Citation Extract:
Lacerra G, Sierakowska H, Carestia C, Fucharoen S, Summerton J, Weller D, Kole R. Restoration of hemoglobin A synthesis in erythroid cells from peripheral blood of thalassemic patients. Proc Natl Acad Sci U S A 2000 Aug 15;97(17):9591-6.

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