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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Methods for introducing morpholinos into the chicken embryo

Authors:
Kos R, Tucker RP, Hall R, Duong TD, Erickson CA
Citation:
Dev Dyn 2003 Mar;226(3):470-7
Epub:
Not Epub
Abstract:
The use of antisense morpholino oligos to inhibit the translation of a target transcript has been applied recently to studies...
Delivery Method:
Electroporation
Organism or Cell Type:
chick embryo
Citation Extract:
Kos R, Tucker RP, Hall R, Duong TD, Erickson CA. Methods for introducing morpholinos into the chicken embryo. Dev Dyn 2003 Mar;226(3):470-7.

Micromanipulation of Gene Expression in the Adult Zebrafish Brain Using Cerebroventricular Microinjection of Morpholino Oligonucleotides

Authors:
Kizil C, Iltzsche A, Kaslin J, Brand M
Citation:
J Vis Exp. 2013;(75):e50415, doi:10.3791/50415
Epub:
Not Epub
Abstract:
Manipulation of gene expression in tissues is required to perform functional studies. In this paper, we demonstrate the...
Delivery Method:
Vivo-Morpholino: cerebroventricular microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kizil C, Iltzsche A, Kaslin J, Brand M. Micromanipulation of Gene Expression in the Adult Zebrafish Brain Using Cerebroventricular Microinjection of Morpholino Oligonucleotides. J Vis Exp. 2013;(75):e50415, doi:10.3791/50415.

miR-21 represses Pdcd4 during cardiac valvulogenesis

Authors:
Kolpa HJ, Peal DS, Lynch SN, Giokas AC, Ghatak S, Misra S, Norris RA, Macrae CA, Markwald RR, Ellinor P, Bischoff J, Milan DJ
Citation:
Development. 2013 May;140(10):2172-80. doi: 10.1242/dev.084475. Epub 2013 Apr 11
Epub:
Not Epub
Abstract:
The discovery of small non-coding microRNAs has revealed novel mechanisms of post-translational regulation of gene expression,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kolpa HJ, Peal DS, Lynch SN, Giokas AC, Ghatak S, Misra S, Norris RA, Macrae CA, Markwald RR, Ellinor P, Bischoff J, Milan DJ. miR-21 represses Pdcd4 during cardiac valvulogenesis. Development. 2013 May;140(10):2172-80. doi: 10.1242/dev.084475. Epub 2013 Apr 11.

misty somites, a maternal effect gene identified by transposon-mediated insertional mutagenesis in zebrafish that is essential for the somite boundary maintenance

Authors:
Kotani T, Kawakami K
Citation:
Dev Biol. 22008 Apr 15;316(2):383-96. Epub 2008 Feb 13.
Epub:
Not Epub
Abstract:
Somite boundary formation is crucial for segmentation of vertebrate somites and vertebrae and skeletal muscle morphogenesis....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kotani T, Kawakami K. misty somites, a maternal effect gene identified by transposon-mediated insertional mutagenesis in zebrafish that is essential for the somite boundary maintenance. Dev Biol. 22008 Apr 15;316(2):383-96. Epub 2008 Feb 13..

Molecular characterization and expression pattern of taurine transporter in zebrafish during embryogenesis

Authors:
Kozlowski DJ, Chen Z, Zhuang L, Fei YJ, Navarre S, Ganapathy V
Citation:
Life Sci. 2008 May 7;82(19-20):1004-11. Epub 2008 Mar 8.
Epub:
Not Epub
Abstract:
Taurine and its transporter (TauT) are expressed in preimplantation embryos, but their role in embryogenesis is not known. To...
Organism or Cell Type:
zebrafish
Citation Extract:
Kozlowski DJ, Chen Z, Zhuang L, Fei YJ, Navarre S, Ganapathy V. Molecular characterization and expression pattern of taurine transporter in zebrafish during embryogenesis. Life Sci. 2008 May 7;82(19-20):1004-11. Epub 2008 Mar 8..

Mutations in SPAG1 Cause Primary Ciliary Dyskinesia Associated with Defective Outer and Inner Dynein Arms

Authors:
Knowles MR, Ostrowski LE, Loges NT, Hurd T, Leigh MW, Huang L, Wolf WE, Carson JL, Hazucha MJ, Yin W, Davis SD, Dell SD, Ferkol TW, Sagel SD, Olivier KN, Jahnke C, Olbrich H, Werner C, Raidt J, Wallmeier J, Pennekamp P, Dougherty GW, Hjeij R, Gee HY, Otto EA, Halbritter J, Chaki M, Diaz KA, Braun DA, Porath JD, Schueler M, Baktai G, Griese M, Turner EH, Lewis AP, Bamshad MJ, Nickerson DA, Hildebrandt F, Shendure J, Omran H, Zariwala MA
Citation:
Am J Hum Genet. 2013;[Epu ahead of print] doi:10.1016/j.ajhg.2013.07.025
Epub:
Not Epub
Abstract:
Primary ciliary dyskinesia (PCD) is a genetically heterogeneous, autosomal-recessive disorder, characterized by oto-sino-...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Knowles MR, Ostrowski LE, Loges NT, Hurd T, Leigh MW, Huang L, Wolf WE, Carson JL, Hazucha MJ, Yin W, Davis SD, Dell SD, Ferkol TW, Sagel SD, Olivier KN, Jahnke C, Olbrich H, Werner C, Raidt J, Wallmeier J, Pennekamp P, Dougherty GW, Hjeij R, Gee HY, Otto EA, Halbritter J, Chaki M, Diaz KA, Braun DA, Porath JD, Schueler M, Baktai G, Griese M, Turner EH, Lewis AP, Bamshad MJ, Nickerson DA, Hildebrandt F, Shendure J, Omran H, Zariwala MA. Mutations in SPAG1 Cause Primary Ciliary Dyskinesia Associated with Defective Outer and Inner Dynein Arms. Am J Hum Genet. 2013;[Epu ahead of print] doi:10.1016/j.ajhg.2013.07.025.

Mys Protein Regulates Protein Kinase A Activity by Interacting with Regulatory Type Ialpha Subunit during Vertebrate Development

Authors:
Kotani T, Iemura S, Natsume T, Kawakami K, Yamashita M
Citation:
J Biol Chem. 2010 Feb 12;285(7):5106-16. Epub 2009 Dec 14
Epub:
Not Epub
Abstract:
During embryonic development, protein kinase A (PKA) plays a key role in cell fate specification by antagonizing the Hedgehog (...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kotani T, Iemura S, Natsume T, Kawakami K, Yamashita M. Mys Protein Regulates Protein Kinase A Activity by Interacting with Regulatory Type Ialpha Subunit during Vertebrate Development. J Biol Chem. 2010 Feb 12;285(7):5106-16. Epub 2009 Dec 14.

Negative regulation of Hedgehog signaling by the cholesterogenic enzyme 7-dehydrocholesterol reductase

Authors:
Koide T, Hayata T, Cho KW
Citation:
Development. 2006 Jun;133(12):2395-405. Epub 2006 May 10
Epub:
Not Epub
Abstract:
Cholesterol regulates Hedgehog (Hh) signaling during early vertebrate development. Smith-Lemli-Opitz syndrome (SLOS) is caused...
Organism or Cell Type:
Xenopus
Citation Extract:
Koide T, Hayata T, Cho KW. Negative regulation of Hedgehog signaling by the cholesterogenic enzyme 7-dehydrocholesterol reductase. Development. 2006 Jun;133(12):2395-405. Epub 2006 May 10.

Neuron navigator 3a regulates liver organogenesis during zebrafish embryogenesis

Authors:
Klein C, Mikutta J, Krueger J, Scholz K, Brinkmann J, Liu D, Veerkamp J, Siegel D, Abdelilah-Seyfried S, le Noble F
Citation:
Development. 2011 Apr 6. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Endodermal organogenesis requires a precise orchestration of cell fate specification and cell movements, collectively...
Organism or Cell Type:
zebrafish
Citation Extract:
Klein C, Mikutta J, Krueger J, Scholz K, Brinkmann J, Liu D, Veerkamp J, Siegel D, Abdelilah-Seyfried S, le Noble F. Neuron navigator 3a regulates liver organogenesis during zebrafish embryogenesis. Development. 2011 Apr 6. [Epub ahead of print].

Nucleocytoplasmic functions of the PDZ-LIM protein family: new insights into organ development

Authors:
Krcmery J, Camarata T, Kulisz A, Simon HG
Citation:
Bioessays. 2010 Feb;32(2):100-8. Review
Epub:
Not Epub
Abstract:
Recent work on the PDZ-LIM protein family has revealed that it has important activities at the cellular level, mediating...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Krcmery J, Camarata T, Kulisz A, Simon HG. Nucleocytoplasmic functions of the PDZ-LIM protein family: new insights into organ development. Bioessays. 2010 Feb;32(2):100-8. Review.

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