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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Systemic Delivery of a Peptide-Linked Morpholino Oligonucleotide Neutralizes Mutant RNA Toxicity in a Mouse Model of Myotonic Dystrophy
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Citation:
Nucleic Acid Ther. 2013 Jan 11. [Epub ahead of print] Epub:
Not Epub Abstract:
Expansions of CUG trinucleotide sequences in RNA transcripts provide the basis for toxic RNA gain-of-function that leads to... Delivery Method:
peptide-coupled Organism or Cell Type:
mouse HSA(LR) Citation Extract: Leger AJ, Mosquea LM, Clayton NP, Wu IH, Weeden T, Nelson CA, Phillips L, Roberts E, Piepenhagen PA, Cheng SH, Wentworth BM. Systemic Delivery of a Peptide-Linked Morpholino Oligonucleotide Neutralizes Mutant RNA Toxicity in a Mouse Model of Myotonic Dystrophy. Nucleic Acid Ther. 2013 Jan 11. [Epub ahead of print]. |
TACE/ADAM-17 Phosphorylation by PKC-Epsilon Mediates Premalignant Changes in Tobacco Smoke-Exposed Lung Cells
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Citation:
PLoS ONE. 2011;6(3):e17489. doi:10.1371/journal.pone.0017489 Epub:
Not Epub Abstract:
Background Tobacco smoke predisposes humans and animals to develop lung tumors, but the molecular events responsible for this... Organism or Cell Type:
cell culture: NCIH292 Citation Extract: Lemjabbar-Alaoui H, Sidhu SS, Mengistab A, Gallup M, Basbaum C. TACE/ADAM-17 Phosphorylation by PKC-Epsilon Mediates Premalignant Changes in Tobacco Smoke-Exposed Lung Cells. PLoS ONE. 2011;6(3):e17489. doi:10.1371/journal.pone.0017489. |
The Function of Heterodimeric AP-1 Comprised of c-Jun and c-Fos in Activin Mediated Spemann Organizer Gene Expression
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Citation:
PLoS ONE. 2011;6(7):e21796. doi:10.1371/journal.pone.0021796 Epub:
Not Epub Abstract:
Background Activator protein-1 (AP-1) is a mediator of BMP or FGF signaling during Xenopus embryogenesis. However, specific... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Lee SY, Yoon J, Lee HS, Hwang YS, Cha S-W, Jeong CH, Kim JI, Park JB, Lee JY, Kim SC, Park MJ, Dong Z, Kim J. The Function of Heterodimeric AP-1 Comprised of c-Jun and c-Fos in Activin Mediated Spemann Organizer Gene Expression. PLoS ONE. 2011;6(7):e21796. doi:10.1371/journal.pone.0021796. |
The Meckel syndrome protein meckelin (TMEM67) is a key regulator of cilia function but is not required for tissue planar polarity
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Citation:
Hum Mol Genet. 2013 Feb 7. [Epub ahead of print] Epub:
Not Epub Abstract:
Meckel syndrome (MKS) is a lethal disorder associated with renal cystic disease, encephalocele, ductal plate malformation, and... Organism or Cell Type:
zebrafish Citation Extract: Leightner AC, Hommerding CJ, Peng Y, Salisbury JL, Gainullin VG, Czarnecki PG, Sussman CR, Harris PC. The Meckel syndrome protein meckelin (TMEM67) is a key regulator of cilia function but is not required for tissue planar polarity. Hum Mol Genet. 2013 Feb 7. [Epub ahead of print]. |
The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction
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Citation:
Development. 2009 Oct;136(19):3267-78 Epub:
Not Epub Abstract:
Wnt signalling is required for neural crest (NC) induction; however, the direct targets of the Wnt pathway during NC induction... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Li B, Kuriyama S, Moreno M, Mayor R. The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction. Development. 2009 Oct;136(19):3267-78. |
The RNA-binding protein Seb4/RBM24 is a direct target of MyoD and is required for myogenesis during Xenopus early development
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Citation:
Mech Dev. 2010 Mar 22. [Epub ahead of print] Epub:
Not Epub Abstract:
RNA-binding proteins play an important role to post-transcriptionally regulate gene expression. During early development they... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Li HY, Bourdelas A, Carron C, Shi DL. The RNA-binding protein Seb4/RBM24 is a direct target of MyoD and is required for myogenesis during Xenopus early development. Mech Dev. 2010 Mar 22. [Epub ahead of print]. |
The role of XTRAP-gamma in Xenopus pronephros development
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Citation:
Int J Dev Biol. 2005 Jun;49(4):401-408 Epub:
Not Epub Abstract:
We isolated and characterized the Xenopus translocon-associated protein XTRAP-gamma, one of four subunits of the translocon-... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Li DH, Chan T, Satow R, Komazaki S, Hashizume K, Asashima M. The role of XTRAP-gamma in Xenopus pronephros development. Int J Dev Biol. 2005 Jun;49(4):401-408. |
The shroom family proteins play broad roles in the morphogenesis of thickened epithelial sheets
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Citation:
Dev Dyn. 2009 Jun;238(6):1480-91 Epub:
Not Epub Abstract:
Thickened epithelial sheets are found in a wide variety of organ systems and the mechanisms governing their morphogenesis... Organism or Cell Type:
Xenopus laevis Citation Extract: Lee C, Le MP, Wallingford JB. The shroom family proteins play broad roles in the morphogenesis of thickened epithelial sheets. Dev Dyn. 2009 Jun;238(6):1480-91. |
The zebrafish forkhead transcription factor Foxi1 specifies epibranchial placode-derived sensory neurons
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Citation:
Development. 2003 Jun;130(12):2669-79 Epub:
Not Epub Abstract:
Vertebrate epibranchial placodes give rise to visceral sensory neurons that transmit vital information such as heart rate,... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Lee SA, Shen EL, Fiser A, Sali A, Guo S. The zebrafish forkhead transcription factor Foxi1 specifies epibranchial placode-derived sensory neurons. Development. 2003 Jun;130(12):2669-79. |
The zebrafish homologue of mammalian chimerin Rac-GAPs is implicated in epiboly progression during development
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Citation:
Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5373-8. Epub 2006 Mar 28. Epub:
Not Epub Abstract:
In this paper, we report an in vivo model for the chimerins, a family of Rac GTPase-activating proteins (Rac-GAPs) that are... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Leskow FC, Holloway BA, Wang H, Mullins MC, Kazanietz MG. The zebrafish homologue of mammalian chimerin Rac-GAPs is implicated in epiboly progression during development. Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5373-8. Epub 2006 Mar 28.. |