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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Transcriptional regulation of Zic3 by heterodimeric AP-1(c-Jun/c-Fos) during Xenopus development

Authors:
Lee SY, Lee HS, Moon JS, Kim JI, Park JB, Lee JY, Park MJ, Kim JB
Citation:
Exp Mol Med. 2004 Oct 31;36(5):468-475
Epub:
Not Epub
Abstract:
The heterodimeric c-Jun/c-Fos, an activator protein-1 (AP-1) has been implicated in mesoderm induction (Dong et al., 1996; Kim...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Lee SY, Lee HS, Moon JS, Kim JI, Park JB, Lee JY, Park MJ, Kim JB. Transcriptional regulation of Zic3 by heterodimeric AP-1(c-Jun/c-Fos) during Xenopus development. Exp Mol Med. 2004 Oct 31;36(5):468-475.

Two additional midline barriers function with midline lefty1 expression to maintain asymmetric Nodal signaling during left-right axis specification in zebrafish

Authors:
Lenhart KF, Lin SY, Titus TA, Postlethwait JH, Burdine RD
Citation:
Development. 2011 Oct;138(20):4405-10. doi: 10.1242/dev.071092
Epub:
Not Epub
Abstract:
Left-right (L/R) patterning is crucial for the proper development of all vertebrates and requires asymmetric expression of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lenhart KF, Lin SY, Titus TA, Postlethwait JH, Burdine RD. Two additional midline barriers function with midline lefty1 expression to maintain asymmetric Nodal signaling during left-right axis specification in zebrafish. Development. 2011 Oct;138(20):4405-10. doi: 10.1242/dev.071092.

Uncoupling VEGFA Functions in Arteriogenesis and Hematopoietic Stem Cell Specification

Authors:
Leung A, Ciau-Uitz A, Pinheiro P, Monteiro R, Zuo J, Vyas P, Patient R, Porcher C
Citation:
Dev Cell. 2013;[Epub ahead of print] http://dx.doi.org/10.1016/j.devcel.2012.12.004
Epub:
Not Epub
Abstract:
VEGFA signaling is critical for endothelial and hematopoietic stem cell (HSC) specification. However, blood defects resulting...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Leung A, Ciau-Uitz A, Pinheiro P, Monteiro R, Zuo J, Vyas P, Patient R, Porcher C. Uncoupling VEGFA Functions in Arteriogenesis and Hematopoietic Stem Cell Specification. Dev Cell. 2013;[Epub ahead of print] http://dx.doi.org/10.1016/j.devcel.2012.12.004.

Using 32-Cell Stage Xenopus Embryos to Probe PCP Signaling

Authors:
Lee HS, Sokol SY, Moody SA, Daar IO
Citation:
Methods Mol Biol. 2012;839:91-104
Epub:
Not Epub
Abstract:
Use of loss-of function (via antisense Morpholino oligonucleotides (MOs)) or over-expression of proteins in epithelial cells...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Lee HS, Sokol SY, Moody SA, Daar IO. Using 32-Cell Stage Xenopus Embryos to Probe PCP Signaling. Methods Mol Biol. 2012;839:91-104.

Wnt1 and wnt10b function redundantly at the zebrafish midbrain-hindbrain boundary.

Authors:
Lekven AC, Buckles GR, Kostakis N, Moon RT
Citation:
Dev Biol 2003 Feb 15;254(2):172-87
Epub:
Not Epub
Abstract:
Wnt signals have been shown to be involved in multiple steps of vertebrate neural patterning, yet the relative contributions of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lekven AC, Buckles GR, Kostakis N, Moon RT. Wnt1 and wnt10b function redundantly at the zebrafish midbrain-hindbrain boundary.. Dev Biol 2003 Feb 15;254(2):172-87.

Xenopus Reduced Folate Carrier Regulates Neural Crest Development Epigenetically

Authors:
Li J, Shi Y, Sun J, Zhang Y, Mao B
Citation:
PLoS ONE. 2011;6(11): e27198. doi:10.1371/journal.pone.0027198
Epub:
Not Epub
Abstract:
Folic acid deficiency during pregnancy causes birth neurocristopathic malformations resulting from aberrant development of...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Li J, Shi Y, Sun J, Zhang Y, Mao B. Xenopus Reduced Folate Carrier Regulates Neural Crest Development Epigenetically. PLoS ONE. 2011;6(11): e27198. doi:10.1371/journal.pone.0027198.

XPteg (Xenopus Proximal Tubules-Expressed Gene) Is Essential for Pronephric Mesoderm Specification and Tubulogenesis

Authors:
Lee SJ, Kim S, Choi SC, Han JK
Citation:
Mech Dev. 2009 Nov 9. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Retinoic acid (RA) signaling is important for the early steps of nephrogenic cell fate specification. Here, we report a novel...
Organism or Cell Type:
Xenopus
Citation Extract:
Lee SJ, Kim S, Choi SC, Han JK. XPteg (Xenopus Proximal Tubules-Expressed Gene) Is Essential for Pronephric Mesoderm Specification and Tubulogenesis. Mech Dev. 2009 Nov 9. [Epub ahead of print].

XRab40 and XCullin5 form a ubiquitin ligase complex essential for the noncanonical Wnt pathway

Authors:
Lee RHK, Iioka H, Ohashi M, Iemura SI, Natsume T, Kinoshita N
Citation:
EMBO J. 2007;26:3592–606
Epub:
Not Epub
Abstract:
Rab GTPases are key regulators of intracellular membrane trafficking. We sought to elucidate the roles of Rab GTPases in...
Organism or Cell Type:
Xenopus
Citation Extract:
Lee RHK, Iioka H, Ohashi M, Iemura SI, Natsume T, Kinoshita N. XRab40 and XCullin5 form a ubiquitin ligase complex essential for the noncanonical Wnt pathway. EMBO J. 2007;26:3592–606.

Zebrafish blowout provides genetic evidence for Patched1-mediated negative regulation of Hedgehog signaling within the proximal optic vesicle of the vertebrate eye

Authors:
Lee J, Willer JR, Willer GB, Smith K, Gregg RG, Gross JM
Citation:
Dev Biol. 2008 Jul 1;319(1):10-22. Epub 2008 Apr 4
Epub:
Not Epub
Abstract:
In this study, we have characterized the ocular defects in the recessive zebrafish mutant blowout that presents with a variably...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee J, Willer JR, Willer GB, Smith K, Gregg RG, Gross JM. Zebrafish blowout provides genetic evidence for Patched1-mediated negative regulation of Hedgehog signaling within the proximal optic vesicle of the vertebrate eye. Dev Biol. 2008 Jul 1;319(1):10-22. Epub 2008 Apr 4.

Zebrafish G protein {gamma}2 is required for VEGF signaling during angiogenesis

Authors:
Leung T, Chen H, Stauffer AM, Giger KE, Sinha S, Horstick EJ, Humbert JE, Hansen CA, Robishaw JD
Citation:
Blood. 2006 Jul 1;108(1):160-6. Epub 2006 Mar 14.
Epub:
Not Epub
Abstract:
Vascular endothelial growth factor (VEGF) is a major mediator of pathological angiogenesis, a process necessary for the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Leung T, Chen H, Stauffer AM, Giger KE, Sinha S, Horstick EJ, Humbert JE, Hansen CA, Robishaw JD. Zebrafish G protein {gamma}2 is required for VEGF signaling during angiogenesis. Blood. 2006 Jul 1;108(1):160-6. Epub 2006 Mar 14..

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