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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Directional migration of neural crest cells in vivo is regulated by Syndecan-4/Rac1 and non-canonical Wnt signaling/RhoA
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Citation:
Development. 2008 May;135(10):1771-80. Epub 2008 Apr 9. Epub:
Not Epub Abstract:
Directed cell migration is crucial for development, but most of our current knowledge is derived from in vitro studies. We... Citation Extract: Matthews HK, Marchant L, Carmona-Fontaine C, Kuriyama S, Larraín J, Holt MR, Parsons M, Mayor R. Directional migration of neural crest cells in vivo is regulated by Syndecan-4/Rac1 and non-canonical Wnt signaling/RhoA. Development. 2008 May;135(10):1771-80. Epub 2008 Apr 9.. |
Disruption of Eaat2b, a glutamate transporter, results in abnormal motor behaviors in developing zebrafish
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Citation:
Dev Biol. 2011 Nov 6. [Epub ahead of print] Epub:
Not Epub Abstract:
Analysis of zebrafish mutants that have defects in motor behavior can allow entrée into the hindbrain and spinal cord networks... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: McKeown KA, Moreno R, Hall VL, Ribera AB, Downes GB. Disruption of Eaat2b, a glutamate transporter, results in abnormal motor behaviors in developing zebrafish. Dev Biol. 2011 Nov 6. [Epub ahead of print]. |
Diversification of oral and aboral mesodermal regulatory states in pregastrular sea urchin embryos
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Citation:
Dev Biol. 2013 Mar 1;375(1):92-104. doi: 10.1016/j.ydbio.2012.11.033. Epub 2012 Dec 19 Epub:
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Specification of the non-skeletogenic mesoderm (NSM) in sea urchin embryos depends on Delta signaling. Signal reception leads... Delivery Method:
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sea urchin Citation Extract: Materna SC, Ransick A, Li E, Davidson EH. Diversification of oral and aboral mesodermal regulatory states in pregastrular sea urchin embryos. Dev Biol. 2013 Mar 1;375(1):92-104. doi: 10.1016/j.ydbio.2012.11.033. Epub 2012 Dec 19. |
Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization
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Citation:
Circulation. 2009 Aug 18;120(7):553-9. Epub 2009 Aug 3 Epub:
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BACKGROUND: Cardiac repolarization, the process by which cardiomyocytes return to their resting potential after each beat, is a... Delivery Method:
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zebrafish Citation Extract: Milan DJ, Kim AM, Winterfield JR, Jones IL, Pfeufer A, Sanna S, Arking DE, Amsterdam AH, Sabeh KM, Mably JD, Rosenbaum DS, Peterson RT, Chakravarti A, Kääb S, Roden DM, MacRae CA. Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization. Circulation. 2009 Aug 18;120(7):553-9. Epub 2009 Aug 3. |
Drugs that induce repolarization abnormalities cause bradycardia in zebrafish
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Citation:
Circulation. 2003 Mar 18;107(10):1355-8. Epub:
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BACKGROUND: Drug-induced QT prolongation and torsades de pointes remain significant and often unpredictable clinical problems.... Delivery Method:
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zebrafish Citation Extract: Milan DJ, Peterson TA, Ruskin JN, Peterson RT, MacRae CA. Drugs that induce repolarization abnormalities cause bradycardia in zebrafish. Circulation. 2003 Mar 18;107(10):1355-8.. |
Eteplirsen for the treatment of duchenne muscular dystrophy
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Citation:
Ann Neurol. 2013;74(5):637-647 doi:10.1002/ana.23982 Epub:
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Objective In prior open-label studies, eteplirsen, a phosphorodiamidate morpholino oligomer (PMO), enabled dystrophin... Delivery Method:
iv infusion Organism or Cell Type:
human Citation Extract: Mendell J, Rodino-Klapac LR, Sahenk Z, Roush K, Bird L, Lowes LP, Alfano L, Gomez AM, Lewis S, Kota J, Malik V, Shontz K, Walker CM, Flanigan KM, Kean JR, Allen HD, Shilling C, Melia KR, Sazani P, Saoud JB, Kaye EM, The Eteplirsen Study Group. Eteplirsen for the treatment of duchenne muscular dystrophy. Ann Neurol. 2013;74(5):637-647 doi:10.1002/ana.23982. |
Extracellular cleavage of cadherin-11 by ADAM metalloproteases is essential for Xenopus cranial neural crest cell migration
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Citation:
Mol Biol Cell. 2009 Jan;20(1):78-89. Epub 2008 Oct 22. Erratum in: Mol Biol Cell. 2010 May;21(9):1643 Epub:
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Cell adhesion molecules such as cadherins alternate their expression throughout cranial neural crest (CNC) development, yet our... Delivery Method:
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Xenopus laevis Citation Extract: McCusker C, Cousin H, Neuner R, Alfandari D. Extracellular cleavage of cadherin-11 by ADAM metalloproteases is essential for Xenopus cranial neural crest cell migration. Mol Biol Cell. 2009 Jan;20(1):78-89. Epub 2008 Oct 22. Erratum in: Mol Biol Cell. 2010 May;21(9):1643. |
FAK induces expression of Prx1 to promote tenascin-C-dependent fibroblast migration
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Citation:
J Cell Biol. 2003 Apr 28;161(2):393-402 Epub:
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Fibroblast migration depends, in part, on activation of FAK and cellular interactions with tenascin-C (TN-C). Consistent with... Delivery Method:
Special Delivery Organism or Cell Type:
Cell culture: mouse FAK-wild-type fibroblasts from E8.5 mice Citation Extract: McKean DM, Sisbarro L, Ilic D, Kaplan-Alburquerque N, Nemenoff R, Weiser-Evans M, Kern MJ, Jones PL. FAK induces expression of Prx1 to promote tenascin-C-dependent fibroblast migration. J Cell Biol. 2003 Apr 28;161(2):393-402. |
ff1b, the SF1 ortholog, is important for pancreatic islet cell development in zebrafish
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Citation:
Mol Genet Metab. 2010 Oct 1. [Epub ahead of print] Epub:
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The adrenal cortex and pancreatic islets have endocrine functions, producing steroid-based hormones and insulin, respectively.... Organism or Cell Type:
zebrafish Citation Extract: Mazilu JK, Powers JW, Lin S, McCabe ER. ff1b, the SF1 ortholog, is important for pancreatic islet cell development in zebrafish. Mol Genet Metab. 2010 Oct 1. [Epub ahead of print]. |
Fibrillin-2b regulates endocardial morphogenesis in zebrafish
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Citation:
Dev Biol. 2012;[Epub ahead of print] doi:10.1016/j.ydbio.2012.07.015 Epub:
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Scotch tape (sco) is a zebrafish cardiac mutant initially proposed to exhibit a reduced amount of cardiac jelly, the... Delivery Method:
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zebrafish Citation Extract: Mellman K, Huisken J, Dinsmore C, Hoppe C, Stainier DY. Fibrillin-2b regulates endocardial morphogenesis in zebrafish. Dev Biol. 2012;[Epub ahead of print] doi:10.1016/j.ydbio.2012.07.015. |