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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

B7-h1 is expressed by human endothelial cells and suppresses T cell cytokine synthesis

Authors:
Mazanet MM, Hughes CC
Citation:
J Immunol. 2002 Oct 1;169(7):3581-8
Epub:
Not Epub
Abstract:
Human endothelial cells (ECs) provide costimulatory signals sufficient to activate resting memory T cells to produce IL-2 and...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture:human endothelial cells (ECs)
Citation Extract:
Mazanet MM, Hughes CC. B7-h1 is expressed by human endothelial cells and suppresses T cell cytokine synthesis. J Immunol. 2002 Oct 1;169(7):3581-8.

Backbone Modification of Nucleic Acids: Synthesis, Structure and Therapeutic Applications

Authors:
Micklefield J
Citation:
Curr Med Chem. 2001 Aug;8(10):1157-79.
Epub:
Not Epub
Abstract:
Nucleic acids have been extensively modified by replacing the phosphodiester group or the whole sugar phosphodiester with...
Delivery Method:
not applicable
Organism or Cell Type:
not applicable
Citation Extract:
Micklefield J. Backbone Modification of Nucleic Acids: Synthesis, Structure and Therapeutic Applications. Curr Med Chem. 2001 Aug;8(10):1157-79..

Bbs8, together with the planar cell polarity protein Vangl2, is required to establish left-right asymmetry in zebrafish

Authors:
May-Simera HL, Kai M, Hernandez V, Osborn DP, Tada M, Beales PL
Citation:
Dev Biol. 2010 Jul 16. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Laterality defects such as situs inversus are not uncommonly encountered in humans, either in isolation or as part of another...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
May-Simera HL, Kai M, Hernandez V, Osborn DP, Tada M, Beales PL. Bbs8, together with the planar cell polarity protein Vangl2, is required to establish left-right asymmetry in zebrafish. Dev Biol. 2010 Jul 16. [Epub ahead of print].

C1q-like inhibits p53-mediated apoptosis and controls normal hematopoiesis during zebrafish embryogenesis

Authors:
Mei J, Zhang QY, Li Z, Lin S, Gui JF
Citation:
Dev Biol. 2008 Jul 15;319(2):273-84. Epub 2008 Apr 25.
Epub:
Not Epub
Abstract:
Except for the complement C1q, the immunological functions of other C1q family members have remained unclear. Here we describe...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mei J, Zhang QY, Li Z, Lin S, Gui JF. C1q-like inhibits p53-mediated apoptosis and controls normal hematopoiesis during zebrafish embryogenesis. Dev Biol. 2008 Jul 15;319(2):273-84. Epub 2008 Apr 25..

Canopy1, a positive feedback regulator of FGF signaling, controls progenitor cell clustering during Kupffer's vesicle organogenesis

Authors:
Matsui T, Thitamadee S, Murata T, Kakinuma H, Nabetani T, Hirabayashi Y, Hirate Y, Okamoto H, Bessho Y
Citation:
Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):9881-6. Epub 2011 May 31
Epub:
Not Epub
Abstract:
The assembly of progenitor cells is a crucial step for organ formation during vertebrate development. Kupffer's vesicle (...
Organism or Cell Type:
zebrafish
Citation Extract:
Matsui T, Thitamadee S, Murata T, Kakinuma H, Nabetani T, Hirabayashi Y, Hirate Y, Okamoto H, Bessho Y. Canopy1, a positive feedback regulator of FGF signaling, controls progenitor cell clustering during Kupffer's vesicle organogenesis. Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):9881-6. Epub 2011 May 31.

Caspy: A Zebrafish caspase activated by ASC oligomerization required for pharyngeal Arch development

Authors:
Masumoto J, Zhou W, Chen FF, Su F, Kuwada JY, Hidaka E, Katsuyama T, Sagara J, Taniguchi S, Ngo-Hazelett P, Postlethwait JH, Nunez G, Inohara N
Citation:
J Biol Chem. 2003 Feb 7;278(6):4268-76. Epub 2002 Dec 02.
Epub:
Not Epub
Abstract:
The pyrin domain was identified recently in multiple proteins that are associated with apoptosis and/or inflammation, but the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Masumoto J, Zhou W, Chen FF, Su F, Kuwada JY, Hidaka E, Katsuyama T, Sagara J, Taniguchi S, Ngo-Hazelett P, Postlethwait JH, Nunez G, Inohara N. Caspy: A Zebrafish caspase activated by ASC oligomerization required for pharyngeal Arch development. J Biol Chem. 2003 Feb 7;278(6):4268-76. Epub 2002 Dec 02..

Cationic phosphorodiamidate morpholino oligomers efficiently prevent growth of Escherichia coli in vitro and in vivo

Authors:
Mellbye BL, Weller DD, Hassinger JN, Reeves MD, Lovejoy CE, Iversen PL, Geller BL
Citation:
J Antimicrob Chemother. 2009 Nov 1. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Objectives Phosphorodiamidate morpholino oligomers (PMOs) are uncharged DNA analogues that can inhibit bacterial growth by a...
Delivery Method:
Cationic backbone modifications
Organism or Cell Type:
Escherichia coli, Escerichia coli infection in mice
Citation Extract:
Mellbye BL, Weller DD, Hassinger JN, Reeves MD, Lovejoy CE, Iversen PL, Geller BL. Cationic phosphorodiamidate morpholino oligomers efficiently prevent growth of Escherichia coli in vitro and in vivo. J Antimicrob Chemother. 2009 Nov 1. [Epub ahead of print].

CCDC39 is required for assembly of inner dynein arms and the dynein regulatory complex and for normal ciliary motility in humans and dogs

Authors:
Merveille AC, Davis EE, Becker-Heck A, Legendre M, Amirav I, Bataille G, Belmont J, Beydon N, Billen F, Clément A, Clercx C, Coste A, Crosbie R, de Blic J, Deleuze S, Duquesnoy P, Escalier D, Escudier E, Fliegauf M, Horvath J, Hill K, Jorissen M, Just J, Kispert A, Lathrop M, Loges NT, Marthin JK, Momozawa Y, Montantin G, Nielsen KG, Olbrich H, Papon JF, Rayet I, Roger G, Schmidts M, Tenreiro H, Towbin JA, Zelenika D, Zentgraf H, Georges M, Lequarr� AS, Katsanis N, Omran H, Amselem S
Citation:
Nat Genet. 2010 Dec 5. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Primary ciliary dyskinesia (PCD) is an inherited disorder characterized by recurrent infections of the upper and lower...
Organism or Cell Type:
zebrafish
Citation Extract:
Merveille AC, Davis EE, Becker-Heck A, Legendre M, Amirav I, Bataille G, Belmont J, Beydon N, Billen F, Clément A, Clercx C, Coste A, Crosbie R, de Blic J, Deleuze S, Duquesnoy P, Escalier D, Escudier E, Fliegauf M, Horvath J, Hill K, Jorissen M, Just J, Kispert A, Lathrop M, Loges NT, Marthin JK, Momozawa Y, Montantin G, Nielsen KG, Olbrich H, Papon JF, Rayet I, Roger G, Schmidts M, Tenreiro H, Towbin JA, Zelenika D, Zentgraf H, Georges M, Lequarr� AS, Katsanis N, Omran H, Amselem S . CCDC39 is required for assembly of inner dynein arms and the dynein regulatory complex and for normal ciliary motility in humans and dogs. Nat Genet. 2010 Dec 5. [Epub ahead of print].

Cdc2-Cyclin B triggers H3 kinase activation of aurora-A in xenopus oocytes.

Authors:
Maton G, Thibier C, Castro A, Lorca T, Prigent C, Jessus C.
Citation:
J Biol Chem. 2003 Jun 13;278(24):21439-49. Epub 2003 Apr 01.
Epub:
Not Epub
Abstract:
Xenopus oocytes are arrested in meiotic prophase I and resume meiotic divisions in response to progesterone. Progesterone...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Maton G, Thibier C, Castro A, Lorca T, Prigent C, Jessus C.. Cdc2-Cyclin B triggers H3 kinase activation of aurora-A in xenopus oocytes.. J Biol Chem. 2003 Jun 13;278(24):21439-49. Epub 2003 Apr 01..

Celf1 regulation of dmrt2a is required for somite symmetry and left-right patterning during zebrafish development

Authors:
Matsui T, Sasaki A, Akazawa N, Otani H, Bessho Y
Citation:
Development. 2012 Aug 16. [Epub ahead of print]
Epub:
Not Epub
Abstract:
RNA-binding proteins (RBPs) bind to numerous and diverse mRNAs to control gene expression post-transcriptionally, although the...
Organism or Cell Type:
zebrafish
Citation Extract:
Matsui T, Sasaki A, Akazawa N, Otani H, Bessho Y. Celf1 regulation of dmrt2a is required for somite symmetry and left-right patterning during zebrafish development. Development. 2012 Aug 16. [Epub ahead of print].

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