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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12511 scientific papers returned from the database with the search filters currently being used below.

Improved Protocol for the Synthesis of Flexibly Protected Morpholino Monomers from Unprotected Ribonucleosides

Authors:
Pattanayak S, Paul S, Nandi B, Sinha S
Citation:
Nucleosides, Nucleotides and Nucleic Acids. 2012;31(11):763-82 doi:10.1080/15257770.2012.724491
Epub:
Not Epub
Abstract:
An inexpensive and much improved protocol has been developed for the synthesis of protected morpholino monomers from...
Citation Extract:
Pattanayak S, Paul S, Nandi B, Sinha S. Improved Protocol for the Synthesis of Flexibly Protected Morpholino Monomers from Unprotected Ribonucleosides. Nucleosides, Nucleotides and Nucleic Acids. 2012;31(11):763-82 doi:10.1080/15257770.2012.724491.

Inhibition of alphavirus infection in cell culture and in mice with antisense morpholino oligomers

Authors:
Paessler S, Rijnbrand R, Stein DA, Ni H, Yun NE, Dziuba N, Borisevich V, Seregin A, Ma Y, Blouch R, Iversen PL, Zacks MA
Citation:
Virology. 2008 Jul 5;376(2):357-70. Epub 2008 May 12.
Epub:
Not Epub
Abstract:
The genus Alphavirus contains members that threaten human health, both as natural pathogens and as potential biological weapons...
Link:
http://www.sciencedirect.com/science/article/pii/S0042682208002043
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice
Citation Extract:
Paessler S, Rijnbrand R, Stein DA, Ni H, Yun NE, Dziuba N, Borisevich V, Seregin A, Ma Y, Blouch R, Iversen PL, Zacks MA. Inhibition of alphavirus infection in cell culture and in mice with antisense morpholino oligomers. Virology. 2008 Jul 5;376(2):357-70. Epub 2008 May 12..

Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction

Authors:
Pera EM, Ikeda A, Eivers E, De Robertis EM
Citation:
Genes Dev. 2003 Dec 15;17(24):3023-8.
Epub:
Not Epub
Abstract:
How do very diverse signaling pathways induce neural differentiation in Xenopus? Anti-BMP (Chordin), FGF8, and IGF2 signals are...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Pera EM, Ikeda A, Eivers E, De Robertis EM. Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction. Genes Dev. 2003 Dec 15;17(24):3023-8..

Interaction between X-Delta-2 and Hox genes regulates segmentation and patterning of the anteroposterior axis

Authors:
Peres JN, McNulty CL, Durston AJ
Citation:
Mech Dev. 2006 Apr;123(4):321-33. Epub 2006 Apr 27.
Epub:
Not Epub
Abstract:
In vertebrates, the paraxial mesoderm already exhibits a complex Hox gene pattern by the time that segmentation occurs and...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Peres JN, McNulty CL, Durston AJ. Interaction between X-Delta-2 and Hox genes regulates segmentation and patterning of the anteroposterior axis. Mech Dev. 2006 Apr;123(4):321-33. Epub 2006 Apr 27..

Isolation of a ventricle-specific promoter for the zebrafish ventricular myosin heavy chain (vmhc) gene and its regulation by GATA factors during embryonic heart development

Authors:
Park JS, Kim HS, Kim JD, Seo J, Chung KS, Lee HS, Huh TL, Jo I, Kim YO
Citation:
Dev Dyn. 2009 May 13;238(6):1574-1581. [Epub ahead of print]
Epub:
Not Epub
Abstract:
We investigated chamber-specific gene expression by isolating a 2.2-kb polymerase chain reaction product containing the 5...
Organism or Cell Type:
zebrafish
Citation Extract:
Park JS, Kim HS, Kim JD, Seo J, Chung KS, Lee HS, Huh TL, Jo I, Kim YO. Isolation of a ventricle-specific promoter for the zebrafish ventricular myosin heavy chain (vmhc) gene and its regulation by GATA factors during embryonic heart development. Dev Dyn. 2009 May 13;238(6):1574-1581. [Epub ahead of print].

Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells

Authors:
Peng JC, Valouev A, Swigut T, Zhang J, Zhao Y, Sidow A, Wysocka J
Citation:
Cell. 2009 Dec 24;139(7):1290-302
Epub:
Not Epub
Abstract:
Polycomb Repressive Complex 2 (PRC2) regulates key developmental genes in embryonic stem (ES) cells and during development....
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Peng JC, Valouev A, Swigut T, Zhang J, Zhao Y, Sidow A, Wysocka J. Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells. Cell. 2009 Dec 24;139(7):1290-302.

Knockdown of FoxO3a induces increased neuronal apoptosis during embryonic development in zebrafish

Authors:
Peng K, Li Y, Long L, Li D, Jia Q, Wang Y, Shen Q, Tang Y, Wen L, Kung HF, Peng Y
Citation:
Neurosci Lett. 2010 Oct 29;484(2):98-103. Epub 2010 Jul 30.
Epub:
Not Epub
Abstract:
Neuronal apoptosis sculpts the developing brain, and nearly all identified classes of neurons seem to be produced \"in...
Organism or Cell Type:
zebrafish
Citation Extract:
Peng K, Li Y, Long L, Li D, Jia Q, Wang Y, Shen Q, Tang Y, Wen L, Kung HF, Peng Y. Knockdown of FoxO3a induces increased neuronal apoptosis during embryonic development in zebrafish. Neurosci Lett. 2010 Oct 29;484(2):98-103. Epub 2010 Jul 30..

L-Leucine improves anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q)MDS by activating the mTOR pathway

Authors:
Payne E, Virgilio M, Narla A, Sun H, Levine M, Paw BH, Berliner N, Look AT, Ebert B, Khanna-Gupta A
Citation:
Blood. 2012 Jun 25. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Haploinsufficiency of ribosomal proteins (RP) has been proposed to be the common basis for the anemia observed in Diamond-...
Organism or Cell Type:
zebrafish
Citation Extract:
Payne E, Virgilio M, Narla A, Sun H, Levine M, Paw BH, Berliner N, Look AT, Ebert B, Khanna-Gupta A. L-Leucine improves anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q)MDS by activating the mTOR pathway. Blood. 2012 Jun 25. [Epub ahead of print].

Lens development depends on a pair of highly conserved Sox21 regulatory elements

Authors:
Pauls S, Smith SF, Elgar G
Citation:
Dev Biol. 2012 Feb 24. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Highly conserved non-coding elements (CNEs) linked to genes involved in embryonic development have been hypothesised to...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pauls S, Smith SF, Elgar G. Lens development depends on a pair of highly conserved Sox21 regulatory elements. Dev Biol. 2012 Feb 24. [Epub ahead of print].

Lhx5 promotes forebrain development and activates transcription of secreted Wnt antagonists

Authors:
Peng G, Westerfield M
Citation:
Development. 2006 Aug;133(16):3191-200. Epub 2006 Jul 19
Epub:
Not Epub
Abstract:
In vertebrate embryos, induction and patterning of the forebrain require the local inhibition of caudalizing signals, such as...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Peng G, Westerfield M. Lhx5 promotes forebrain development and activates transcription of secreted Wnt antagonists. Development. 2006 Aug;133(16):3191-200. Epub 2006 Jul 19.

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