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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Hairy/E(spl)-related (Her) genes are central components of the segmentation oscillator and display redundancy with the Delta/Notch signaling pathway in the formation of anterior segmental boundaries in the zebrafish

Authors:
Oates AC, Ho RK
Citation:
Development 2002 Jun;129(12):2929-46
Epub:
Not Epub
Abstract:
We have examined the expression of a Hairy/E(spl)-related (Her) gene, her7, in the zebrafish and show that its expression in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Oates AC, Ho RK. Hairy/E(spl)-related (Her) genes are central components of the segmentation oscillator and display redundancy with the Delta/Notch signaling pathway in the formation of anterior segmental boundaries in the zebrafish. Development 2002 Jun;129(12):2929-46.

Hhip regulates zebrafish muscle development by both sequestering Hedgehog and modulating localization of Smoothened.

Authors:
Ochi H, Pearson BJ, Chuang PT, Hammerschmidt M, Westerfield M.
Citation:
Dev Biol. 2006 Sep 1;297(1):127-40. Epub 2006 May 6.
Epub:
Not Epub
Abstract:
Sharp borders between cells with different developmental fates are important for patterning of invertebrates, but are not well...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ochi H, Pearson BJ, Chuang PT, Hammerschmidt M, Westerfield M.. Hhip regulates zebrafish muscle development by both sequestering Hedgehog and modulating localization of Smoothened.. Dev Biol. 2006 Sep 1;297(1):127-40. Epub 2006 May 6..

HSPG synthesis by zebrafish Ext2 and Extl3 is required for Fgf10 signalling during limb development

Authors:
Norton WH, Ledin J, Grandel H, Neumann CJ
Citation:
Development. 2005 Nov;132(22):4963-73. Epub 2005 Oct 12
Epub:
Not Epub
Abstract:
Heparan sulphate proteoglycans (HSPGs) are known to be crucial for signalling by the secreted Wnt, Hedgehog, Bmp and Fgf...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Norton WH, Ledin J, Grandel H, Neumann CJ. HSPG synthesis by zebrafish Ext2 and Extl3 is required for Fgf10 signalling during limb development. Development. 2005 Nov;132(22):4963-73. Epub 2005 Oct 12.

Identification of nesfatin-1 as a satiety molecule in the hypothalamus

Authors:
Oh-I S, Shimizu H, Satoh T, Okada S, Adachi S, Inoue K, Eguchi H, Yamamoto M, Imaki T, Hashimoto K, Tsuchiya T, Monden T, Horiguchi K, Yamada M, Mori M
Citation:
Nature. 2006 Oct 12;443(7112):709-12. Epub 2006 Oct 1
Epub:
Not Epub
Abstract:
The brain hypothalamus contains certain secreted molecules that are important in regulating feeding behaviour. Here we show...
Delivery Method:
in vivo: intracerebroventricular injection
Organism or Cell Type:
Rat
Citation Extract:
Oh-I S, Shimizu H, Satoh T, Okada S, Adachi S, Inoue K, Eguchi H, Yamamoto M, Imaki T, Hashimoto K, Tsuchiya T, Monden T, Horiguchi K, Yamada M, Mori M. Identification of nesfatin-1 as a satiety molecule in the hypothalamus. Nature. 2006 Oct 12;443(7112):709-12. Epub 2006 Oct 1.

Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy

Authors:
O'Toole JF, Liu Y, Davis EE, Westlake CJ, Attanasio M, Otto EA, Seelow D, Nurnberg G, Becker C, Nuutinen M, Kärppä M, Ignatius J, Uusimaa J, Pakanen S, Jaakkola E, van den Heuvel LP, Fehrenbach H, Wiggins R, Goyal M, Zhou W, Wolf MT, Wise E, Helou J, Allen SJ, Murga-Zamalloa CA, Ashraf S, Chaki M, Heeringa S, Chernin G, Hoskins BE, Chaib H, Gleeson J, Kusakabe T, Suzuki T, Isaac RE, Quarmby LM, Tennant B, Fujioka H, Tuominen H, Hassinen I, Lohi H, van Houten JL, Rotig A, Sayer JA, Rolinski B, Freisinger P, Madhavan SM, Herzer M, Madignier F, Prokisch H, Nurnberg P, Jackson P, Khanna H, Katsanis N, Hildebrandt F
Citation:
J Clin Invest. 2010 Feb 22. pii: 40076. doi: 10.1172/JCI40076. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The autosomal recessive kidney disease nephronophthisis (NPHP) constitutes the most frequent genetic cause of terminal renal...
Organism or Cell Type:
zebrafish
Citation Extract:
O'Toole JF, Liu Y, Davis EE, Westlake CJ, Attanasio M, Otto EA, Seelow D, Nurnberg G, Becker C, Nuutinen M, Kärppä M, Ignatius J, Uusimaa J, Pakanen S, Jaakkola E, van den Heuvel LP, Fehrenbach H, Wiggins R, Goyal M, Zhou W, Wolf MT, Wise E, Helou J, Allen SJ, Murga-Zamalloa CA, Ashraf S, Chaki M, Heeringa S, Chernin G, Hoskins BE, Chaib H, Gleeson J, Kusakabe T, Suzuki T, Isaac RE, Quarmby LM, Tennant B, Fujioka H, Tuominen H, Hassinen I, Lohi H, van Houten JL, Rotig A, Sayer JA, Rolinski B, Freisinger P, Madhavan SM, Herzer M, Madignier F, Prokisch H, Nurnberg P, Jackson P, Khanna H, Katsanis N, Hildebrandt F. Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy. J Clin Invest. 2010 Feb 22. pii: 40076. doi: 10.1172/JCI40076. [Epub ahead of print].

Inhibition of porcine reproductive and respiratory syndrome virus infection in piglets by a peptide-conjugated morpholino oligomer

Authors:
Opriessnig T, Patel D, Wang R, Halbur PG, Meng XJ, Stein DA, Zhang YJ
Citation:
Antiviral Res. 2011 Jul;91(1):36-42. doi: 10.1016/j.antiviral.2011.04.012. Epub 2011 Apr 30. PMID: 21554902
Epub:
Not Epub
Abstract:
Porcine reproductive and respiratory syndrome (PRRS) causes substantial economic losses to the swine industry in many countries...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0166354211002919
Delivery Method:
Peptide-coupled intranasal
Organism or Cell Type:
pig
Citation Extract:
Opriessnig T, Patel D, Wang R, Halbur PG, Meng XJ, Stein DA, Zhang YJ. Inhibition of porcine reproductive and respiratory syndrome virus infection in piglets by a peptide-conjugated morpholino oligomer. Antiviral Res. 2011 Jul;91(1):36-42. doi: 10.1016/j.antiviral.2011.04.012. Epub 2011 Apr 30. PMID: 21554902.

Interpretation of the FGF8 morphogen gradient is regulated by endocytic trafficking

Authors:
Nowak M, Machate A, Yu SR, Gupta M, Brand M
Citation:
Nat Cell Biol. 2011 Feb;13(2):153-8. Epub 2011 Jan 23
Epub:
Not Epub
Abstract:
Forty years ago, it was proposed that during embryonic development and organogenesis, morphogen gradients provide positional...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nowak M, Machate A, Yu SR, Gupta M, Brand M. Interpretation of the FGF8 morphogen gradient is regulated by endocytic trafficking. Nat Cell Biol. 2011 Feb;13(2):153-8. Epub 2011 Jan 23.

Kinectin-dependent assembly of translation elongation factor-1 complex on endoplasmic reticulum regulates protein synthesis

Authors:
Ong LL, Lin PC, Zhang X, Chia SM, Yu H
Citation:
J Biol Chem. 2006 Nov 3;281(44):33621-34. Epub 2006 Sep 1.
Epub:
Not Epub
Abstract:
Kinectin is an integral membrane protein with many isoforms primarily found on the endoplasmic reticulum. It has been found to...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: HeLa cells
Citation Extract:
Ong LL, Lin PC, Zhang X, Chia SM, Yu H. Kinectin-dependent assembly of translation elongation factor-1 complex on endoplasmic reticulum regulates protein synthesis. J Biol Chem. 2006 Nov 3;281(44):33621-34. Epub 2006 Sep 1..

Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins

Authors:
Omran H, Kobayashi D, Olbrich H, Tsukahara T, Loges NT, Hagiwara H, Zhang Q, Leblond G, O'Toole E, Hara C, Mizuno H, Kawano H, Fliegauf M, Yagi T, Koshida S, Miyawaki A, Zentgraf H, Seithe H, Reinhardt R, Watanabe Y, Kamiya R, Mitchell DR, Takeda H
Citation:
Nature. 2008 Dec 4;456(7222):611-6
Epub:
Not Epub
Abstract:
Cilia/flagella are highly conserved organelles that play diverse roles in cell motility and sensing extracellular signals....
Delivery Method:
Microinjection
Organism or Cell Type:
medaka embryos
Citation Extract:
Omran H, Kobayashi D, Olbrich H, Tsukahara T, Loges NT, Hagiwara H, Zhang Q, Leblond G, O'Toole E, Hara C, Mizuno H, Kawano H, Fliegauf M, Yagi T, Koshida S, Miyawaki A, Zentgraf H, Seithe H, Reinhardt R, Watanabe Y, Kamiya R, Mitchell DR, Takeda H. Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins. Nature. 2008 Dec 4;456(7222):611-6.

Lbx2 regulates formation of myofibrils

Authors:
Ochi H, Westerfield M
Citation:
BMC Dev Biol. 2009 Feb 12;9(1):13. [Epub ahead of print]
Epub:
Not Epub
Abstract:
ABSTRACT: BACKGROUND: Skeletal muscle differentiation requires assembly of contractile proteins into organized myofibrils. The...
Organism or Cell Type:
zebrafish
Citation Extract:
Ochi H, Westerfield M. Lbx2 regulates formation of myofibrils. BMC Dev Biol. 2009 Feb 12;9(1):13. [Epub ahead of print].

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