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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

A novel regulatory circuit in base excision repair involving AP endonuclease 1, Creb1 and DNA polymerase beta

Authors:
Pei DS, Yang XJ, Liu W, Guikema JE, Schrader CE, Strauss PR
Citation:
Nucleic Acids Res. 2011 Apr 1;39(8):3156-65. Epub 2010 Dec 20
Epub:
Not Epub
Abstract:
DNA repair is required to maintain genome stability in stem cells and early embryos. At critical junctures, oxidative damage to...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pei DS, Yang XJ, Liu W, Guikema JE, Schrader CE, Strauss PR. A novel regulatory circuit in base excision repair involving AP endonuclease 1, Creb1 and DNA polymerase beta. Nucleic Acids Res. 2011 Apr 1;39(8):3156-65. Epub 2010 Dec 20.

Removal of dystroglycan causes severe muscular dystrophy in zebrafish embryos.

Authors:
Parsons MJ, Campos I, Hirst EM, Stemple DL
Citation:
Development 2002 Jul;129(14):3505-12
Epub:
Not Epub
Abstract:
Muscular dystrophy is frequently caused by disruption of the dystrophin-glycoprotein complex (DGC), which links muscle cells to...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Parsons MJ, Campos I, Hirst EM, Stemple DL. Removal of dystroglycan causes severe muscular dystrophy in zebrafish embryos.. Development 2002 Jul;129(14):3505-12.

A Mechanism Regulating the Onset of Sox2 Expression in the Embryonic Neural Plate

Authors:
Papanayotou C, Mey A, Birot AM, Saka Y, Boast S, Smith JC, Samarut J, Stern CD
Citation:
PLoS Biol. 2008 Jan 8;6(1):e2 [Epub ahead of print]
Epub:
Not Epub
Abstract:
In vertebrate embryos, the earliest definitive marker for the neural plate, which will give rise to the entire central nervous...
Delivery Method:
Electroporation
Organism or Cell Type:
chick embryo
Citation Extract:
Papanayotou C, Mey A, Birot AM, Saka Y, Boast S, Smith JC, Samarut J, Stern CD. A Mechanism Regulating the Onset of Sox2 Expression in the Embryonic Neural Plate. PLoS Biol. 2008 Jan 8;6(1):e2 [Epub ahead of print].

A model of Costeff Syndrome reveals metabolic and protective functions of mitochondrial OPA3

Authors:
Pei W, Kratz LE, Bernardini I, Sood R, Yokogawa T, Dorward H, Ciccone C, Kelley RI, Anikster Y, Burgess HA, Huizing M, Feldman B
Citation:
Development. 2010 Aug 1;137(15):2587-96
Epub:
Not Epub
Abstract:
Costeff Syndrome, which is caused by mutations in the OPTIC ATROPHY 3 (OPA3) gene, is an early-onset syndrome characterized by...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pei W, Kratz LE, Bernardini I, Sood R, Yokogawa T, Dorward H, Ciccone C, Kelley RI, Anikster Y, Burgess HA, Huizing M, Feldman B. A model of Costeff Syndrome reveals metabolic and protective functions of mitochondrial OPA3. Development. 2010 Aug 1;137(15):2587-96.

A Model of Glucose-6-Phosphate Dehydrogenase Deficiency in the Zebrafish

Authors:
Patrinostro X, Carter ML, Kramer AC, Lund TC
Citation:
Exp Hematol. 2013 Apr 16. doi:pii: S0301-472X(13)00124-0. 10.1016/j.exphem.2013.04.002. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common genetic defect and enzymopathy worldwide, affecting...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Patrinostro X, Carter ML, Kramer AC, Lund TC. A Model of Glucose-6-Phosphate Dehydrogenase Deficiency in the Zebrafish. Exp Hematol. 2013 Apr 16. doi:pii: S0301-472X(13)00124-0. 10.1016/j.exphem.2013.04.002. [Epub ahead of print].

A positive role for the Ku complex in DNA replication following strand break damage in mammals

Authors:
Park SJ, Ciccone SL, Freie B, Kurimasa A, Chen DJ, Li GC, Clapp DW, Lee SH
Citation:
J Biol Chem. 2003 Nov 15 [Epub ahead of print]
Epub:
Not Epub
Abstract:
Ku70/Ku80 complex is the regulatory subunits of DNA-dependent protein kinase (DNA-PK) and plays an essential role in double...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: HeLa cells
Citation Extract:
Park SJ, Ciccone SL, Freie B, Kurimasa A, Chen DJ, Li GC, Clapp DW, Lee SH. A positive role for the Ku complex in DNA replication following strand break damage in mammals. J Biol Chem. 2003 Nov 15 [Epub ahead of print].

A simple method for delivering morpholino antisense oligos into the cytoplasm of cells

Authors:
Partridge M, Vincent A, Matthews P, Puma J, Stein D, Summerton J
Citation:
Antisense Nucleic Acid Drug Dev. 1996 Fall;6(3):169-75
Epub:
Not Epub
Abstract:
We report a simple and effective means for delivering Morpholino antisense oligos into the cytosol of cultured anchorage-...
Delivery Method:
Scrape Delivery
Organism or Cell Type:
cell culture: Hela and rat FT02B liver cells
Citation Extract:
Partridge M, Vincent A, Matthews P, Puma J, Stein D, Summerton J. A simple method for delivering morpholino antisense oligos into the cytoplasm of cells. Antisense Nucleic Acid Drug Dev. 1996 Fall;6(3):169-75.

A Temporal Chromatin Signature in Human Embryonic Stem Cells Identifies Regulators of Cardiac Development

Authors:
Paige SL, Thomas S, Stoick-Cooper CL, Wang H, Maves L, Sandstrom S, Pabon L, Reinecke H, Pratt G, Keller G, Moon RT, Stamatoyannopoulos J, Murry CE
Citation:
Cell. 2012;[Epub ahead of print] doi:10.1016/j.cell.2012.08.027
Epub:
Not Epub
Abstract:
Directed differentiation of human embryonic stem cells (ESCs) into cardiovascular cells provides a model for studying molecular...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Paige SL, Thomas S, Stoick-Cooper CL, Wang H, Maves L, Sandstrom S, Pabon L, Reinecke H, Pratt G, Keller G, Moon RT, Stamatoyannopoulos J, Murry CE. A Temporal Chromatin Signature in Human Embryonic Stem Cells Identifies Regulators of Cardiac Development. Cell. 2012;[Epub ahead of print] doi:10.1016/j.cell.2012.08.027.

An actin cytoskeleton with evolutionarily conserved functions in the absence of canonical actin-binding proteins

Authors:
Paredez AR, Assaf ZJ, Sept D, Timofejeva L, Dawson SC, Wang CJ, Cande WZ
Citation:
Proc Natl Acad Sci U S A. 2011 Apr 12;108(15):6151-6. Epub 2011 Mar 28.
Epub:
Not Epub
Abstract:
Giardia intestinalis, a human intestinal parasite and member of what is perhaps the earliest-diverging eukaryotic lineage,...
Delivery Method:
Electroporation
Organism or Cell Type:
Giardia intestinalis
Citation Extract:
Paredez AR, Assaf ZJ, Sept D, Timofejeva L, Dawson SC, Wang CJ, Cande WZ. An actin cytoskeleton with evolutionarily conserved functions in the absence of canonical actin-binding proteins. Proc Natl Acad Sci U S A. 2011 Apr 12;108(15):6151-6. Epub 2011 Mar 28..

An antisense oligonucleotide to 1-cys peroxiredoxin causes lipid peroxidation and apoptosis in lung epithelial cells

Authors:
Pak JH, Manevich Y, Kim HS, Feinstein SI, Fisher AB
Citation:
J Biol Chem. 2002 Dec 20;277(51):49927-34. Epub 2002 Oct 07
Epub:
Not Epub
Abstract:
1-cys peroxiredoxin (1-cysPrx), a member of the peroxiredoxin superfamily, reduces phospholipid hydroperoxides as well as...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: L2 cells
Citation Extract:
Pak JH, Manevich Y, Kim HS, Feinstein SI, Fisher AB. An antisense oligonucleotide to 1-cys peroxiredoxin causes lipid peroxidation and apoptosis in lung epithelial cells. J Biol Chem. 2002 Dec 20;277(51):49927-34. Epub 2002 Oct 07.

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