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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Monorail/Foxa2 regulates floorplate differentiation and specification of oligodendrocytes, serotonergic raphe neurones and cranial motoneurones

Authors:
Norton WH, Mangoli M, Lele Z, Pogoda HM, Diamond B, Mercurio S, Russell C, Teraoka H, Stickney HL, Rauch GJ, Heisenberg CP, Houart C, Schilling TF, Frohnhoefer HG, Rastegar S, Neumann CJ, Gardiner RM, Strahle U, Geisler R, Rees M, Talbot WS, Wilson SW
Citation:
Development. 2005 Feb;132(4):645-58
Epub:
Not Epub
Abstract:
In this study, we elucidate the roles of the winged-helix transcription factor Foxa2 in ventral CNS development in zebrafish....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Norton WH, Mangoli M, Lele Z, Pogoda HM, Diamond B, Mercurio S, Russell C, Teraoka H, Stickney HL, Rauch GJ, Heisenberg CP, Houart C, Schilling TF, Frohnhoefer HG, Rastegar S, Neumann CJ, Gardiner RM, Strahle U, Geisler R, Rees M, Talbot WS, Wilson SW. Monorail/Foxa2 regulates floorplate differentiation and specification of oligodendrocytes, serotonergic raphe neurones and cranial motoneurones. Development. 2005 Feb;132(4):645-58.

Morpholino Gene Knockdown in Adult Fundulus heteroclitus: Role of SGK1 in Seawater Acclimation

Authors:
Notch EG, Shaw JR, Coutermarsh BA, Dzioba M, Stanton BA
Citation:
PLoS ONE. 2011;6(12): e29462. doi:10.1371/journal.pone.0029462
Epub:
Not Epub
Abstract:
The Atlantic killifish (Fundulus heteroclitus) is an environmental sentinel organism used extensively for studies on...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Fundulus heteroclitus
Citation Extract:
Notch EG, Shaw JR, Coutermarsh BA, Dzioba M, Stanton BA. Morpholino Gene Knockdown in Adult Fundulus heteroclitus: Role of SGK1 in Seawater Acclimation. PLoS ONE. 2011;6(12): e29462. doi:10.1371/journal.pone.0029462.

Morpholino knockdown of the ubiquitously expressed transmembrane serine protease TMPRSS4a in zebrafish embryos exhibits severe defects in organogenesis and cell adhesion

Authors:
Ohler A, Becker-Pauly C
Citation:
Biol Chem. 2011 Jun;392(7):653-64
Epub:
Not Epub
Abstract:
Over the past years the members of the type II transmembrane serine protease (TTSP) family have emerged as new players in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ohler A, Becker-Pauly C. Morpholino knockdown of the ubiquitously expressed transmembrane serine protease TMPRSS4a in zebrafish embryos exhibits severe defects in organogenesis and cell adhesion. Biol Chem. 2011 Jun;392(7):653-64.

Multiple Signaling Pathways Coordinate to Induce a Threshold Response in a Chordate Embryo

Authors:
Ohta N, Satou Y
Citation:
PLoS Genet. 2013;9(10):e1003818. doi:10.1371/journal.pgen.1003818
Epub:
Not Epub
Abstract:
In animal development, secreted signaling molecules evoke all-or-none threshold responses of target gene transcription to...
Delivery Method:
Microinjection
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Ohta N, Satou Y. Multiple Signaling Pathways Coordinate to Induce a Threshold Response in a Chordate Embryo. PLoS Genet. 2013;9(10):e1003818. doi:10.1371/journal.pgen.1003818.

NeuroD regulates proliferation of photoreceptor progenitors in the retina of the zebrafish

Authors:
Ochocinska MJ, Hitchcock PF
Citation:
Mech Dev. 2008 Dec 14. [Epub ahead of print]
Epub:
Not Epub
Abstract:
neuroD is a member of the family of proneural genes, which function to regulate the cell cycle, cell fate determination and...
Organism or Cell Type:
zebrafish
Citation Extract:
Ochocinska MJ, Hitchcock PF. NeuroD regulates proliferation of photoreceptor progenitors in the retina of the zebrafish. Mech Dev. 2008 Dec 14. [Epub ahead of print].

NLK, an essential effector of anterior formation, functions downstream of p38 MAP kinase

Authors:
Ohnishi E, Goto T, Sato A, Kim MS, Iemura SI, Ishitani T, Natsume T, Ohnishi J, Shibuyaup H
Citation:
Mol Cell Biol. 2009 Nov 23. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Nemo-like kinase (NLK) is known to function as a mitogen-activated protein kinase (MAPK)-like kinase. However, the upstream...
Organism or Cell Type:
Xenopus
Citation Extract:
Ohnishi E, Goto T, Sato A, Kim MS, Iemura SI, Ishitani T, Natsume T, Ohnishi J, Shibuyaup H. NLK, an essential effector of anterior formation, functions downstream of p38 MAP kinase. Mol Cell Biol. 2009 Nov 23. [Epub ahead of print].

oko meduzy and related crumbs genes are determinants of apical cell features in the vertebrate embryo

Authors:
Omori Y, Malicki J
Citation:
Curr Biol. 2006 May 23;16(10):945-57
Epub:
Not Epub
Abstract:
BACKGROUND: Polarity is an essential attribute of most eukaryotic cells. One of the most prominent features of cell polarity in...
Organism or Cell Type:
zebrafish
Citation Extract:
Omori Y, Malicki J. oko meduzy and related crumbs genes are determinants of apical cell features in the vertebrate embryo. Curr Biol. 2006 May 23;16(10):945-57.

Perp is required for tissue-specific cell survival during zebrafish development

Authors:
Nowak M, Koster C, Hammerschmidt M
Citation:
Cell Death Differ. 2005 Jan;12(1):52-64
Epub:
Not Epub
Abstract:
The tumor suppressor p53 has two alternative effects, causing either cell cycle arrest or apoptosis. These different effects...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nowak M, Koster C, Hammerschmidt M. Perp is required for tissue-specific cell survival during zebrafish development. Cell Death Differ. 2005 Jan;12(1):52-64.

Plastin 3 is a protective modifier of autosomal recessive spinal muscular atrophy

Authors:
Oprea GE, Kröber S, McWhorter ML, Rossoll W, Müller S, Krawczak M, Bassell GJ, Beattie CE, Wirth B
Citation:
Science. 2008 Apr 25;320(5875):524-7
Epub:
Not Epub
Abstract:
Homozygous deletion of the survival motor neuron 1 gene (SMN1) causes spinal muscular atrophy (SMA), the most frequent genetic...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Oprea GE, Kröber S, McWhorter ML, Rossoll W, Müller S, Krawczak M, Bassell GJ, Beattie CE, Wirth B. Plastin 3 is a protective modifier of autosomal recessive spinal muscular atrophy. Science. 2008 Apr 25;320(5875):524-7.

Polycystin-2 immunolocalization and function in zebrafish

Authors:
Obara T, Mangos S, Liu Y, Zhao J, Wiessner S, Kramer-Zucker AG, Olale F, Schier AF, Drummond IA
Citation:
J Am Soc Nephrol. 2006 Oct;17(10):2706-18. Epub 2006 Aug 30
Epub:
Not Epub
Abstract:
Polycystin-2 functions as a cation-permeable transient receptor potential ion channel in kidney epithelial cells and when...
Organism or Cell Type:
zebrafish
Citation Extract:
Obara T, Mangos S, Liu Y, Zhao J, Wiessner S, Kramer-Zucker AG, Olale F, Schier AF, Drummond IA. Polycystin-2 immunolocalization and function in zebrafish. J Am Soc Nephrol. 2006 Oct;17(10):2706-18. Epub 2006 Aug 30.

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