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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Excessive activity of cathepsin K is associated with cartilage defects in a zebrafish model of mucolipidosis II

Authors:
Petrey AC, Flanagan-Steet H, Johnson S, Fan X, De la Rosa M, Haskins ME, Nairn AV, Moremen KW, Steet R
Citation:
Dis Model Mech. 2012 Mar;5(2):177-90. Epub 2011 Nov 1
Epub:
Not Epub
Abstract:
The severe pediatric disorder mucolipidosis II (ML-II; also known as I-cell disease) is caused by defects in mannose 6-...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Petrey AC, Flanagan-Steet H, Johnson S, Fan X, De la Rosa M, Haskins ME, Nairn AV, Moremen KW, Steet R. Excessive activity of cathepsin K is associated with cartilage defects in a zebrafish model of mucolipidosis II. Dis Model Mech. 2012 Mar;5(2):177-90. Epub 2011 Nov 1.

Filopodia are dispensable for endothelial tip cell guidance

Authors:
Phng LK, Stanchi F, Gerhardt H
Citation:
Development. 2013 Oct;140(19):4031-40. doi: 10.1242/dev.097352
Epub:
Not Epub
Abstract:
Actin filaments are instrumental in driving processes such as migration, cytokinesis and endocytosis and provide cells with...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Phng LK, Stanchi F, Gerhardt H. Filopodia are dispensable for endothelial tip cell guidance. Development. 2013 Oct;140(19):4031-40. doi: 10.1242/dev.097352.

Functional genomics tools for the analysis of zebrafish pigment

Authors:
Pickart MA, Sivasubbu S, Nielsen AL, Shriram S, King RA, Ekker SC
Citation:
Pigment Cell Res. 2004 Oct;17(5):461-70
Epub:
Not Epub
Abstract:
Genetic model organisms are increasingly valuable in the post-genomics era to provide a basis for comparative analysis of the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pickart MA, Sivasubbu S, Nielsen AL, Shriram S, King RA, Ekker SC. Functional genomics tools for the analysis of zebrafish pigment. Pigment Cell Res. 2004 Oct;17(5):461-70.

GATA-6 maintains BMP-4 and Nkx2 expression during cardiomyocyte precursor maturation

Authors:
Peterkin T, Gibson A, Patient R
Citation:
EMBO J. 2003 Aug 15;22(16):4260-73
Epub:
Not Epub
Abstract:
GATA-6 is expressed in presumptive cardiac mesoderm before gastrulation, but its role in heart development has been unclear....
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus and zebrafish
Citation Extract:
Peterkin T, Gibson A, Patient R. GATA-6 maintains BMP-4 and Nkx2 expression during cardiomyocyte precursor maturation. EMBO J. 2003 Aug 15;22(16):4260-73.

Genome-wide reverse genetics framework to identify novel functions of the vertebrate secretome

Authors:
Pickart MA, Klee EW, Nielsen AL, Sivasubbu S, Mendenhall EM, Bill BR, Chen E, Eckfeldt CE, Knowlton M, Robu ME, Larson JD, Deng Y, Schimmenti LA, Ellis LB, Verfaillie CM, Hammerschmidt M, Farber SA, Ekker SC
Citation:
PLoS ONE. 2006 Dec 20;1:e104
Epub:
Not Epub
Abstract:
BACKGROUND: Understanding the functional role(s) of the more than 20,000 proteins of the vertebrate genome is a major next step...
Organism or Cell Type:
zebrafish
Citation Extract:
Pickart MA, Klee EW, Nielsen AL, Sivasubbu S, Mendenhall EM, Bill BR, Chen E, Eckfeldt CE, Knowlton M, Robu ME, Larson JD, Deng Y, Schimmenti LA, Ellis LB, Verfaillie CM, Hammerschmidt M, Farber SA, Ekker SC. Genome-wide reverse genetics framework to identify novel functions of the vertebrate secretome. PLoS ONE. 2006 Dec 20;1:e104.

Harmonin (Ush1c) is required in zebrafish Muller glial cells for photoreceptor synaptic development and function

Authors:
Phillips JB, Blanco-Sanchez B, Lentz JJ, Tallafuss A, Khanobdee K, Sampath S, Jacobs ZG, Han PF, Mishra M, Williams DS, Keats BJ, Washbourne P, Westerfield M
Citation:
Dis Model Mech. 2011 Jul 14. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Usher syndrome is the most prevalent cause of hereditary deaf-blindness, characterized by congenital sensorineural hearing...
Organism or Cell Type:
zebrafish
Citation Extract:
Phillips JB, Blanco-Sanchez B, Lentz JJ, Tallafuss A, Khanobdee K, Sampath S, Jacobs ZG, Han PF, Mishra M, Williams DS, Keats BJ, Washbourne P, Westerfield M. Harmonin (Ush1c) is required in zebrafish Muller glial cells for photoreceptor synaptic development and function. Dis Model Mech. 2011 Jul 14. [Epub ahead of print].

Histone deacetylase 1 (HDAC-1) required for the normal formation of craniofacial cartilage and pectoral fins of the zebrafish

Authors:
Pillai R, Coverdale LE, Dubey G, Martin CC
Citation:
Dev Dyn. 2004 Sep 16;231(3):647-654
Epub:
Not Epub
Abstract:
Histone deacetylases interact with nucleosomes to facilitate the formation of transcriptionally repressed chromatin. In the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pillai R, Coverdale LE, Dubey G, Martin CC. Histone deacetylase 1 (HDAC-1) required for the normal formation of craniofacial cartilage and pectoral fins of the zebrafish. Dev Dyn. 2004 Sep 16;231(3):647-654.

How to make a teleost adenohypophysis: Molecular pathways of pituitary development in zebrafish

Authors:
Pogoda HM, Hammerschmidt M
Citation:
Mol Cell Endocrinol. 2009 Mar 28. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The anterior pituitary gland, or adenohypophysis (AH), represents the key component of the vertebrate hypothalamo-hypophyseal...
Organism or Cell Type:
zebrafish
Citation Extract:
Pogoda HM, Hammerschmidt M. How to make a teleost adenohypophysis: Molecular pathways of pituitary development in zebrafish. Mol Cell Endocrinol. 2009 Mar 28. [Epub ahead of print].

Human embryonic stem cell microenvironment suppresses the tumorigenic phenotype of aggressive cancer cells

Authors:
Postovit LM, Margaryan NV, Seftor EA, Kirschmann DA, Lipavsky A, Wheaton WW, Abbott DE, Seftor RE, Hendrix MJ
Citation:
Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4329-34. Epub 2008 Mar 11
Epub:
Not Epub
Abstract:
Embryonic stem cells sustain a microenvironment that facilitates a balance of self-renewal and differentiation. Aggressive...
Citation Extract:
Postovit LM, Margaryan NV, Seftor EA, Kirschmann DA, Lipavsky A, Wheaton WW, Abbott DE, Seftor RE, Hendrix MJ. Human embryonic stem cell microenvironment suppresses the tumorigenic phenotype of aggressive cancer cells. Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4329-34. Epub 2008 Mar 11.

Implication of the proprotein convertase NARC-1/PCSK9 in the development of the nervous system

Authors:
Poirier S, Prat A, Marcinkiewicz E, Paquin J, Chitramuthu BP, Baranowski D, Cadieux B, Bennett HP, Seidah NG
Citation:
J Neurochem. 2006 Aug;98(3):838-50
Epub:
Not Epub
Abstract:
Neural apoptosis-regulated convertase-1/proprotein convertase subtilisin-kexin like-9 (NARC-1/PCSK9) is a proprotein convertase...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Poirier S, Prat A, Marcinkiewicz E, Paquin J, Chitramuthu BP, Baranowski D, Cadieux B, Bennett HP, Seidah NG. Implication of the proprotein convertase NARC-1/PCSK9 in the development of the nervous system. J Neurochem. 2006 Aug;98(3):838-50.

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