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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Delivery of NADPH-Cytochrome P450 Reductase Antisense Oligos Using Avidin-Biotin Approach

Authors:
Pillai VC, Yesudas R, Shaik IH, Thekkumkara TJ, Bickel U, Srivenugopal KS, Mehvar R
Citation:
Bioconjug Chem. 2010 Jan 11. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Although avidin-mediated intracellular delivery of oligonucleotides or proteins has been shown before, the efficacy studies are...
Delivery Method:
Avadin-biotin system, Endo-Porter
Organism or Cell Type:
Rat liver epithelial cells
Citation Extract:
Pillai VC, Yesudas R, Shaik IH, Thekkumkara TJ, Bickel U, Srivenugopal KS, Mehvar R. Delivery of NADPH-Cytochrome P450 Reductase Antisense Oligos Using Avidin-Biotin Approach. Bioconjug Chem. 2010 Jan 11. [Epub ahead of print].

Design of Phosphorodiamidate Morpholino Oligomers (PMOs) for the Induction of Exon Skipping of the Human DMD Gene

Authors:
Popplewell LJ, Trollet C, Dickson G, Graham IR
Citation:
Mol Ther. 2009 Jan 13. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is caused by out-of-frame mutations of the human DMD gene. Antisense oligonucleotides (AOs)...
Link:
https://www.sciencedirect.com/science/article/pii/S152500161631543X
Organism or Cell Type:
cell culture: human skeletal muscle
Citation Extract:
Popplewell LJ, Trollet C, Dickson G, Graham IR. Design of Phosphorodiamidate Morpholino Oligomers (PMOs) for the Induction of Exon Skipping of the Human DMD Gene. Mol Ther. 2009 Jan 13. [Epub ahead of print] .

Developmental, molecular and genetic dissection of INa in vivo in embryonic zebrafish sensory neurons.

Authors:
Pineda RH, Heiser RA, Ribera AB
Citation:
J Neurophysiol. 2005 Jun;93(6):3582-93. Epub 2005 Jan 26
Epub:
Not Epub
Abstract:
The presence of multiple Nav1 isotypes within a neuron and the lack of specific blockers hamper identification of the in vivo...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pineda RH, Heiser RA, Ribera AB. Developmental, molecular and genetic dissection of INa in vivo in embryonic zebrafish sensory neurons.. J Neurophysiol. 2005 Jun;93(6):3582-93. Epub 2005 Jan 26.

Discovery of therapeutic targets by phenotype-based zebrafish screens

Authors:
Peterson RT
Citation:
Drug Discovery Today: Technologies. 2004 1(1):49-54
Epub:
Not Epub
Abstract:
The easy identification of phenotypes in the transparent zebrafish embryo has enabled numerous genetic, antisense morpholino...
Organism or Cell Type:
zebrafish
Citation Extract:
Peterson RT. Discovery of therapeutic targets by phenotype-based zebrafish screens. Drug Discovery Today: Technologies. 2004 1(1):49-54.

Disruptions of Global and Jagged1-Mediated Notch Signaling Affect Thyroid Morphogenesis in the Zebrafish

Authors:
Porazzi P, Marelli F, Benato F, de Filippis T, Calebiro D, Argenton F, Tiso N, Persani L
Citation:
Endocrinology. 2012 Sep 24. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The mechanisms underlying the early steps of thyroid development are largely unknown. In search for novel candidate genes...
Organism or Cell Type:
zebrafish
Citation Extract:
Porazzi P, Marelli F, Benato F, de Filippis T, Calebiro D, Argenton F, Tiso N, Persani L. Disruptions of Global and Jagged1-Mediated Notch Signaling Affect Thyroid Morphogenesis in the Zebrafish. Endocrinology. 2012 Sep 24. [Epub ahead of print].

Dkk3 is required for TGF-beta signaling during Xenopus mesoderm induction

Authors:
Pinho S, Niehrs C
Citation:
Differentiation. 2007 Dec;75(10):957-67. Epub 2007 May 9.
Epub:
Not Epub
Abstract:
The Dickkopf (Dkk) family is composed of four main members (Dkk1-4), which typically regulate Wnt/beta-catenin signaling. An...
Organism or Cell Type:
Xenopus
Citation Extract:
Pinho S, Niehrs C. Dkk3 is required for TGF-beta signaling during Xenopus mesoderm induction. Differentiation. 2007 Dec;75(10):957-67. Epub 2007 May 9..

Do zebrafish Rh proteins act as dual ammonia-CO(2) channels?

Authors:
Perry SF, Braun MH, Noland M, Dawdy J, Walsh PJ
Citation:
J Exp Zool A Ecol Genet Physiol. 2010 Aug 3. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Transfer of the small gaseous molecules CO(2) and NH(3) across biological membranes, long thought to occur solely by simple...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Perry SF, Braun MH, Noland M, Dawdy J, Walsh PJ. Do zebrafish Rh proteins act as dual ammonia-CO(2) channels?. J Exp Zool A Ecol Genet Physiol. 2010 Aug 3. [Epub ahead of print].

Dorsal-Ventral patterning: Crescent is a dorsally secreted Frizzled-related protein that competitively inhibits Tolloid proteases

Authors:
Ploper D, Lee HX, De Robertis EM
Citation:
Dev Biol. 2011 Feb 2. [Epub ahead of print]
Epub:
Not Epub
Abstract:
In Xenopus, dorsal-ventral (D-V) patterning can self-regulate after embryo bisection. This is mediated by an extracellular...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Ploper D, Lee HX, De Robertis EM. Dorsal-Ventral patterning: Crescent is a dorsally secreted Frizzled-related protein that competitively inhibits Tolloid proteases. Dev Biol. 2011 Feb 2. [Epub ahead of print].

Dvr1 transfers left-right asymmetric signals from Kupffer's vesicle to lateral plate mesoderm in zebrafish

Authors:
Peterson AG, Wang X, Joseph Yost H
Citation:
Dev Biol. 2013 Jun 17. doi:pii: S0012-1606(13)00328-X. 10.1016/j.ydbio.2013.06.011. [Epub ahead of print]
Epub:
Not Epub
Abstract:
An early step in establishing left-right (LR) symmetry in zebrafish is the generation of asymmetric fluid flow by Kupffer'...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Peterson AG, Wang X, Joseph Yost H. Dvr1 transfers left-right asymmetric signals from Kupffer's vesicle to lateral plate mesoderm in zebrafish. Dev Biol. 2013 Jun 17. doi:pii: S0012-1606(13)00328-X. 10.1016/j.ydbio.2013.06.011. [Epub ahead of print].

Dynamic coupling of pattern formation and morphogenesis in the developing vertebrate retina

Authors:
Picker A, Cavodeassi F, Machate A, Bernauer S, Hans S, Abe G, Kawakami K, Wilson SW, Brand M
Citation:
PLoS Biol. 2009 Oct;7(10):e1000214. Epub 2009 Oct 13
Epub:
Not Epub
Abstract:
During embryonic development, pattern formation must be tightly synchronized with tissue morphogenesis to coordinate the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Picker A, Cavodeassi F, Machate A, Bernauer S, Hans S, Abe G, Kawakami K, Wilson SW, Brand M. Dynamic coupling of pattern formation and morphogenesis in the developing vertebrate retina. PLoS Biol. 2009 Oct;7(10):e1000214. Epub 2009 Oct 13.

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