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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Insm1a-mediated gene repression is essential for the formation and differentiation of Müller glia-derived progenitors in the injured retina

Authors:
Ramachandran R, Zhao XF, Goldman D
Citation:
Nat Cell Biol. 2012 Oct;14(10):1013-23. doi: 10.1038/ncb2586. Epub 2012 Sep 23
Epub:
Not Epub
Abstract:
In zebrafish, retinal injury stimulates Müller glia (MG) reprograming, allowing them to generate multipotent progenitors that...
Delivery Method:
in vivo: injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Ramachandran R, Zhao XF, Goldman D. Insm1a-mediated gene repression is essential for the formation and differentiation of Müller glia-derived progenitors in the injured retina. Nat Cell Biol. 2012 Oct;14(10):1013-23. doi: 10.1038/ncb2586. Epub 2012 Sep 23.

Integration of Canonical and Noncanonical Wnt Signaling Pathways Patterns the Neuroectoderm Along the Anterior–Posterior Axis of Sea Urchin Embryos

Authors:
Range RC, Angerer RC, Angerer LM
Citation:
PLoS Biol. 2013 11(1):e1001467. doi:10.1371/journal.pbio.1001467
Epub:
Not Epub
Abstract:
The initial regulatory state of most cells in many deuterostome embryos, including those of vertebrates and sea urchins,...
Delivery Method:
Microinjection
Organism or Cell Type:
Sea urchin, Strongylocentrotus purpuratus
Citation Extract:
Range RC, Angerer RC, Angerer LM. Integration of Canonical and Noncanonical Wnt Signaling Pathways Patterns the Neuroectoderm Along the Anterior–Posterior Axis of Sea Urchin Embryos. PLoS Biol. 2013 11(1):e1001467. doi:10.1371/journal.pbio.1001467.

KIF7 mutations cause fetal hydrolethalus and acrocallosal syndromes

Authors:
Putoux A, Thomas S, Coene KL, Davis EE, Alanay Y, Ogur G, Uz E, Buzas D, Gomes C, Patrier S, Bennett CL, Elkhartoufi N, Frison MH, Rigonnot L, Joyé N, Pruvost S, Utine GE, Boduroglu K, Nitschke P, Fertitta L, Thauvin-Robinet C, Munnich A, Cormier-Daire V, Hennekam R, Colin E, Akarsu NA, Bole-Feysot C, Cagnard N, Schmitt A, Goudin N, Lyonnet S, Encha-Razavi F, Siffroi JP, Winey M, Katsanis N, Gonzales M, Vekemans M, Beales PL, Attié-Bitach T
Citation:
Nat Genet. 2011 Jun;43(6):601-6. Epub 2011 May 8
Epub:
Not Epub
Abstract:
KIF7, the human ortholog of Drosophila Costal2, is a key component of the Hedgehog signaling pathway. Here we report mutations...
Organism or Cell Type:
zebrafish
Citation Extract:
Putoux A, Thomas S, Coene KL, Davis EE, Alanay Y, Ogur G, Uz E, Buzas D, Gomes C, Patrier S, Bennett CL, Elkhartoufi N, Frison MH, Rigonnot L, Joyé N, Pruvost S, Utine GE, Boduroglu K, Nitschke P, Fertitta L, Thauvin-Robinet C, Munnich A, Cormier-Daire V, Hennekam R, Colin E, Akarsu NA, Bole-Feysot C, Cagnard N, Schmitt A, Goudin N, Lyonnet S, Encha-Razavi F, Siffroi JP, Winey M, Katsanis N, Gonzales M, Vekemans M, Beales PL, Attié-Bitach T. KIF7 mutations cause fetal hydrolethalus and acrocallosal syndromes. Nat Genet. 2011 Jun;43(6):601-6. Epub 2011 May 8.

Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3

Authors:
Ragvin A, Moro E, Fredman D, Navratilova P, Drivenes O, Engström PG, Alonso ME, Mustienes ED, Skarmeta JL, Tavares MJ, Casares F, Manzanares M, van Heyningen V, Molven A, Njølstad PR, Argenton F, Lenhard B, Becker TS
Citation:
Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):775-780. Epub 2009 Dec 22
Epub:
Not Epub
Abstract:
Genome-wide association studies identified noncoding SNPs associated with type 2 diabetes and obesity in linkage disequilibrium...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ragvin A, Moro E, Fredman D, Navratilova P, Drivenes O, Engström PG, Alonso ME, Mustienes ED, Skarmeta JL, Tavares MJ, Casares F, Manzanares M, van Heyningen V, Molven A, Njølstad PR, Argenton F, Lenhard B, Becker TS. Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3. Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):775-780. Epub 2009 Dec 22.

Loss of Xenopus tropicalis EMSY causes impairment of gastrulation and upregulation of p53

Authors:
Rana AA, Roper SJ, Palmer EA, Smith JC
Citation:
N Biotechnol. 2010 Nov 4. [Epub ahead of print]
Epub:
Not Epub
Abstract:
EMSY interacts directly with BRCA2 and links the BRCA2 pathway to sporadic breast and ovarian cancer. It also interacts with...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Rana AA, Roper SJ, Palmer EA, Smith JC. Loss of Xenopus tropicalis EMSY causes impairment of gastrulation and upregulation of p53. N Biotechnol. 2010 Nov 4. [Epub ahead of print].

LvNumb works synergistically with Notch signaling to specify non-skeletal mesoderm cells in the sea urchin embryo

Authors:
Range RC, Glenn TD, Miranda E, McClay DR
Citation:
Development. 2008 Jul;135(14):2445-54. Epub 2008 Jun 11.
Epub:
Not Epub
Abstract:
Activation of the Notch signaling pathway segregates the non-skeletogenic mesoderm (NSM) from the endomesoderm during sea...
Delivery Method:
Microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Range RC, Glenn TD, Miranda E, McClay DR. LvNumb works synergistically with Notch signaling to specify non-skeletal mesoderm cells in the sea urchin embryo. Development. 2008 Jul;135(14):2445-54. Epub 2008 Jun 11..

Maternal Oct1/2 is required for Nodal and Vg1/Univin expression during dorsal-ventral axis specification in the sea urchin embryo

Authors:
Range R, Lepage T
Citation:
Dev Biol. 2011 Jul 12. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The TGFβ family member Nodal is expressed early in the presumptive ventral ectoderm of the early sea urchin embryo and its...
Organism or Cell Type:
P. lividus
Citation Extract:
Range R, Lepage T. Maternal Oct1/2 is required for Nodal and Vg1/Univin expression during dorsal-ventral axis specification in the sea urchin embryo. Dev Biol. 2011 Jul 12. [Epub ahead of print].

Microarray Analysis of Prothrombin Knockdown in Zebrafish

Authors:
Pudur J
Citation:
Journal of Thrombosis and Haemostasis 2007; Volume 5, Supplement 1 :P1212
Epub:
Not Epub
Abstract:
Prothrombin is the zymogen of thrombin that plays a pivotal role in coagulation. Knockdown of prothrombin in the zebrafish was...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pudur J. Microarray Analysis of Prothrombin Knockdown in Zebrafish. Journal of Thrombosis and Haemostasis 2007; Volume 5, Supplement 1 :P1212.

Mmp23b promotes liver development and hepatocyte proliferation through the tumor necrosis factor pathway in zebrafish

Authors:
Qi F, Song J, Yang H, Gao W, Liu NA, Zhang B, Lin S
Citation:
Hepatology. 2010 Aug 31:2159-2167. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The matrix metalloproteinase (MMP) family of proteins degrades extracellular matrix (ECM) components as well as processes...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Qi F, Song J, Yang H, Gao W, Liu NA, Zhang B, Lin S. Mmp23b promotes liver development and hepatocyte proliferation through the tumor necrosis factor pathway in zebrafish. Hepatology. 2010 Aug 31:2159-2167. [Epub ahead of print].

Multiple Ribosomal Proteins Are Expressed at High Levels in Developing Zebrafish Endoderm and Are Required for Normal Exocrine Pancreas Development

Authors:
Provost E, Weier CA, Leach SD
Citation:
Zebrafish. 2013 May 22. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Ribosomal protein L (rpl) genes are essential for assembly of the 60S subunit of the eukaryotic ribosome and may also carry out...
Organism or Cell Type:
zebrafish
Citation Extract:
Provost E, Weier CA, Leach SD. Multiple Ribosomal Proteins Are Expressed at High Levels in Developing Zebrafish Endoderm and Are Required for Normal Exocrine Pancreas Development. Zebrafish. 2013 May 22. [Epub ahead of print].

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