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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Combining Cep290 and Mkks ciliopathy alleles in mice rescues sensory defects and restores ciliogenesis
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Citation:
J Clin Invest. 2012;[Epub ahead of print] doi:10.1172/JCI60981 Epub:
Not Epub Abstract:
Cilia are highly specialized microtubule-based organelles that have pivotal roles in numerous biological processes, including... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Rachel RA, May-Simera HL, Veleri S, Gotoh N, Choi BY, Murga-Zamalloa C, McIntyre JC, Marek J, Lopez I, Hackett AN, Brooks M, den Hollander AI, Beales PL, Li T, Jacobson SG, Sood R, Martens JR, Liu P, Friedman TB, Khanna H, Koenekoop RK, Kelley MW, Swaroop A. Combining Cep290 and Mkks ciliopathy alleles in mice rescues sensory defects and restores ciliogenesis. J Clin Invest. 2012;[Epub ahead of print] doi:10.1172/JCI60981 . |
Defining Synphenotype Groups in Xenopus tropicalis by Use of Antisense Morpholino Oligonucleotides
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Citation:
PLoS Genet. 2006 Nov 17;2(11):e193. Epub 2006 Oct 4. Epub:
Not Epub Abstract:
To identify novel genes involved in early development, and as proof-of-principle of a large-scale reverse genetics approach in... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Rana AA, Collart C, Gilchrist MJ, Smith JC. Defining Synphenotype Groups in Xenopus tropicalis by Use of Antisense Morpholino Oligonucleotides. PLoS Genet. 2006 Nov 17;2(11):e193. Epub 2006 Oct 4.. |
Distinct functions for different scl isoforms in zebrafish primitive and definitive hematopoiesis
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Citation:
PLoS Biol. 2007 May;5(5):e132 Epub:
Not Epub Abstract:
The stem-cell leukemia (SCL, also known as TAL1) gene encodes a basic helix-loop-helix transcription factor that is essential... Organism or Cell Type:
zebrafish Citation Extract: Qian F, Zhen F, Xu J, Huang M, Li W, Wen Z. Distinct functions for different scl isoforms in zebrafish primitive and definitive hematopoiesis. PLoS Biol. 2007 May;5(5):e132. |
DNA demethylase activity maintains intestinal cells in an undifferentiated state following loss of APC
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Citation:
Cell. 2010 Sep 17;142(6):930-42 Epub:
Not Epub Abstract:
Although genome-wide hypomethylation is a hallmark of many cancers, roles for active DNA demethylation during tumorigenesis are... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Rai K, Sarkar S, Broadbent TJ, Voas M, Grossmann KF, Nadauld LD, Dehghanizadeh S, Hagos FT, Li Y, Toth RK, Chidester S, Bahr TM, Johnson WE, Sklow B, Burt R, Cairns BR, Jones DA. DNA demethylase activity maintains intestinal cells in an undifferentiated state following loss of APC. Cell. 2010 Sep 17;142(6):930-42. |
DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45
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Citation:
Cell. 2008 Dec 26;135(7):1201-12 Epub:
Not Epub Abstract:
Evidence for active DNA demethylation in vertebrates is accumulating, but the mechanisms and enzymes remain unclear. Using... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Rai K, Huggins IJ, James SR, Karpf AR, Jones DA, Cairns BR. DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45. Cell. 2008 Dec 26;135(7):1201-12. |
Dnmt2 functions in the cytoplasm to promote liver, brain, and retina development in zebrafish
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Citation:
Genes Dev. 2007 Feb 1;21(3):261-6 Epub:
Not Epub Abstract:
The roles of DNA methyltransferase-2 (DNMT2) enzymes are controversial; whether DNMT2 functions primarily as a nuclear DNA... Organism or Cell Type:
zebrafish Citation Extract: Rai K, Chidester S, Zavala CV, Manos EJ, James SR, Karpf AR, Jones DA, Cairns BR. Dnmt2 functions in the cytoplasm to promote liver, brain, and retina development in zebrafish. Genes Dev. 2007 Feb 1;21(3):261-6. |
Dnmt3 and G9a cooperate for tissue-specific development in zebrafish
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Citation:
J Biol Chem. 2009 Nov 29. [Epub ahead of print] Epub:
Not Epub Abstract:
Although DNA methylation is critical for proper embryonic and tissue-specific development, how different DNA methyltransferases... Organism or Cell Type:
zebrafish Citation Extract: Rai K, Jafri IF, Chidester S, James SR, Karpf AR, Cairns BR, Jones DA. Dnmt3 and G9a cooperate for tissue-specific development in zebrafish. J Biol Chem. 2009 Nov 29. [Epub ahead of print]. |
Endocrine-committed progenitor cells retain their differentiation potential in the absence of neurogenin-3 expression
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Citation:
Biochem Biophys Res Commun. 2010 Jun 11;396(4):1036-41. doi: 10.1016/j.bbrc.2010.05.058. Epub 2010 May 13 Epub:
Not Epub Abstract:
Neurogenin-3 (ngn-3) expression is critical for endocrine development in the developing pancreas. We found that when ngn-3 was... Delivery Method:
oligo bathing Organism or Cell Type:
Mouse pancreas explant Citation Extract: Prasadan K, Tulachan S, Guo P, Shiota C, Shah S, Gittes G. Endocrine-committed progenitor cells retain their differentiation potential in the absence of neurogenin-3 expression. Biochem Biophys Res Commun. 2010 Jun 11;396(4):1036-41. doi: 10.1016/j.bbrc.2010.05.058. Epub 2010 May 13. |
Endoderm-derived Sonic hedgehog and mesoderm Hand2 expression are required for enteric nervous system development in zebrafish
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Citation:
Dev Biol. 2008 Jun 1;318(1):52-64. Epub 2008 Mar 20 Epub:
Not Epub Abstract:
The zebrafish enteric nervous system (ENS), like those of all other vertebrate species, is principally derived from the vagal... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Reichenbach B, Delalande JM, Kolmogorova E, Prier A, Nguyen T, Smith CM, Holzschuh J, Shepherd IT. Endoderm-derived Sonic hedgehog and mesoderm Hand2 expression are required for enteric nervous system development in zebrafish. Dev Biol. 2008 Jun 1;318(1):52-64. Epub 2008 Mar 20. |
Exploring Zebrafish Genomic, Functional and Phenotypic Data Using ZFIN
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Citation:
Curr Protoc Bioinformatics. 2010 Sep;Chapter 1:Unit1.18 Epub:
Not Epub Abstract:
The zebrafish model organism database (ZFIN) provides a Web resource of zebrafish genomic, genetic, developmental, and... Organism or Cell Type:
zebrafish Citation Extract: Ramachandran S, Ruef B, Pich C, Sprague J. Exploring Zebrafish Genomic, Functional and Phenotypic Data Using ZFIN. Curr Protoc Bioinformatics. 2010 Sep;Chapter 1:Unit1.18. |