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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

STAT5 acts as a repressor to regulate early embryonic erythropoiesis

Authors:
Schmerer M, Torregroza I, Pascal A, Umbhauer M, Evans T
Citation:
Blood. 2006 Nov 1;108(9):2989-97. Epub 2006 Jul 11.
Epub:
Not Epub
Abstract:
STAT5 regulates definitive (adult stage) erythropoiesis through its ability to transduce signals from the erythropoietin...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Schmerer M, Torregroza I, Pascal A, Umbhauer M, Evans T. STAT5 acts as a repressor to regulate early embryonic erythropoiesis. Blood. 2006 Nov 1;108(9):2989-97. Epub 2006 Jul 11..

Structural and functional characterization of the zebrafish lamin B receptor

Authors:
Schild-Prufert K, Giegerich M, Schafer M, Winkler C, Krohne G
Citation:
Eur J Cell Biol. 2006 Aug;85(8):813-24. Epub 2006 Jun 6.
Epub:
Not Epub
Abstract:
The lamin B receptor (LBR) is an integral membrane protein of the inner nuclear membrane that is interacting with B-type lamins...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schild-Prufert K, Giegerich M, Schafer M, Winkler C, Krohne G. Structural and functional characterization of the zebrafish lamin B receptor. Eur J Cell Biol. 2006 Aug;85(8):813-24. Epub 2006 Jun 6..

Systemically delivered antisense oligomers upregulate gene expression in mouse tissues

Authors:
Sazani P, Gemignani F, Kang SH, Maier MA, Manoharan M, Persmark M, Bortner D, Kole R
Citation:
Nat Biotechnol. 2002 Dec;20(12):1228-33
Epub:
Not Epub
Abstract:
Systemically injected 2'-O-methoxyethyl (2'-O-MOE)-phosphorothioate and PNA-4K oligomers (peptide nucleic acid with...
Delivery Method:
in vivo: injection
Organism or Cell Type:
Mice: EGFP transgenic
Citation Extract:
Sazani P, Gemignani F, Kang SH, Maier MA, Manoharan M, Persmark M, Bortner D, Kole R. Systemically delivered antisense oligomers upregulate gene expression in mouse tissues. Nat Biotechnol. 2002 Dec;20(12):1228-33.

The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4

Authors:
Sayer JA, Otto EA, O'toole JF, Nurnberg G, Kennedy MA, Becker C, Hennies HC, Helou J, Attanasio M, Fausett BV, Utsch B, Khanna H, Liu Y, Drummond I, Kawakami I, Kusakabe T, Tsuda M, Ma L, Lee H, Larson RG, Allen SJ, Wilkinson CJ, Nigg EA, Shou C, Lillo C, Williams DS, Hoppe B, Kemper MJ, Neuhaus T, Parisi MA, Glass IA, Petry M, Kispert A, Gloy J, Ganner A, Walz G, Zhu X, Goldman D, Nurnberg P, Swaroop A, Leroux MR, Hildebrandt F
Citation:
Nat Genet. 2006 Jun;38(6):674-81. Epub 2006 May 7
Epub:
Not Epub
Abstract:
The molecular basis of nephronophthisis, the most frequent genetic cause of renal failure in children and young adults, and its...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sayer JA, Otto EA, O'toole JF, Nurnberg G, Kennedy MA, Becker C, Hennies HC, Helou J, Attanasio M, Fausett BV, Utsch B, Khanna H, Liu Y, Drummond I, Kawakami I, Kusakabe T, Tsuda M, Ma L, Lee H, Larson RG, Allen SJ, Wilkinson CJ, Nigg EA, Shou C, Lillo C, Williams DS, Hoppe B, Kemper MJ, Neuhaus T, Parisi MA, Glass IA, Petry M, Kispert A, Gloy J, Ganner A, Walz G, Zhu X, Goldman D, Nurnberg P, Swaroop A, Leroux MR, Hildebrandt F. The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4. Nat Genet. 2006 Jun;38(6):674-81. Epub 2006 May 7.

The endosomal protein Appl1 mediates Akt substrate specificity and cell survival in vertebrate development

Authors:
Schenck A, Goto-Silva L, Collinet C, Rhinn M, Giner A, Habermann B, Brand M, Zerial M
Citation:
Cell. 2008 May 2;133(3):486-97
Epub:
Not Epub
Abstract:
During development of multicellular organisms, cells respond to extracellular cues through nonlinear signal transduction...
Organism or Cell Type:
zebrafish
Citation Extract:
Schenck A, Goto-Silva L, Collinet C, Rhinn M, Giner A, Habermann B, Brand M, Zerial M. The endosomal protein Appl1 mediates Akt substrate specificity and cell survival in vertebrate development. Cell. 2008 May 2;133(3):486-97.

The kinesin KIF1B{beta} acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor

Authors:
Schlisio S, Kenchappa RS, Vredeveld LC, George RE, Stewart R, Greulich H, Shahriari K, Nguyen NV, Pigny P, Dahia PL, Pomeroy SL, Maris JM, Look AT, Meyerson M, Peeper DS, Carter BD, Kaelin WG Jr
Citation:
Genes Dev. 2008 Apr 1;22(7):884-93. Epub 2008 Mar 11
Epub:
Not Epub
Abstract:
VHL, NF-1, c-Ret, and Succinate Dehydrogenase Subunits B and D act on a developmental apoptotic pathway that is activated when...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schlisio S, Kenchappa RS, Vredeveld LC, George RE, Stewart R, Greulich H, Shahriari K, Nguyen NV, Pigny P, Dahia PL, Pomeroy SL, Maris JM, Look AT, Meyerson M, Peeper DS, Carter BD, Kaelin WG Jr. The kinesin KIF1B{beta} acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor. Genes Dev. 2008 Apr 1;22(7):884-93. Epub 2008 Mar 11.

The Nedd4-binding protein 3 (N4BP3) is crucial for axonal and dendritic branching in developing neurons

Authors:
Schmeisser MJ, Kühl SJ, Schoen M, Beth NH, Weis TM, Grabrucker AM, Kühl M, Boeckers TM
Citation:
Neural Dev. 2013;[Email ahead of print] doi:10.1186/1749-8104-8-18
Epub:
Not Epub
Abstract:
Background Circuit formation in the nervous system essentially relies on the proper development of neurons and their processes...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Schmeisser MJ, Kühl SJ, Schoen M, Beth NH, Weis TM, Grabrucker AM, Kühl M, Boeckers TM. The Nedd4-binding protein 3 (N4BP3) is crucial for axonal and dendritic branching in developing neurons. Neural Dev. 2013;[Email ahead of print] doi:10.1186/1749-8104-8-18.

The Role of mbx in Zebrafish Brain Development

Authors:
Scharf L
Citation:
BUG Journal. 2003; Vol.6 (MIT)
Epub:
Not Epub
Abstract:
The dividing cells in an embryo need to specialize into particular types of cells as the embryo develops from a single cell...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Scharf L. The Role of mbx in Zebrafish Brain Development. BUG Journal. 2003; Vol.6 (MIT).

Therapeutic potential of antisense oligonucleotides as modulators of alternative splicing

Authors:
Sazani P, Kole R
Citation:
J Clin Invest. 2003 Aug;112(4):481-6
Epub:
Not Epub
Abstract:
An estimated 60% of all human genes undergo alternative splicing, a highly regulated process that produces splice variants with...
Citation Extract:
Sazani P, Kole R. Therapeutic potential of antisense oligonucleotides as modulators of alternative splicing. J Clin Invest. 2003 Aug;112(4):481-6.

Ventx Factors Function as Nanog-Like Guardians of Developmental Potential in Xenopus

Authors:
Scerbo P, Girardot F, Vivien C, Markov GV, Luxardi G, Demeneix B, Kodjabachian L, Coen L
Citation:
PLoS ONE. 2012;7(5): e36855. doi:10.1371/journal.pone.0036855
Epub:
Not Epub
Abstract:
Vertebrate development requires progressive commitment of embryonic cells into specific lineages through a continuum of signals...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Scerbo P, Girardot F, Vivien C, Markov GV, Luxardi G, Demeneix B, Kodjabachian L, Coen L. Ventx Factors Function as Nanog-Like Guardians of Developmental Potential in Xenopus. PLoS ONE. 2012;7(5): e36855. doi:10.1371/journal.pone.0036855.

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