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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Inhibition of zebrafish fin regeneration using in vivo electroporation of morpholinos against fgfr1 and msxb

Authors:
Thummel R, Bai S, Sarras MP Jr, Song P, McDermott J, Brewer J, Perry M, Zhang X, Hyde DR, Godwin AR
Citation:
Dev Dyn. 2006 Feb;235(2):336-46.
Epub:
Not Epub
Abstract:
Increased interest in using zebrafish as a model organism has led to a resurgence of fin regeneration studies. This has allowed...
Delivery Method:
microinjection and in vivo electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Thummel R, Bai S, Sarras MP Jr, Song P, McDermott J, Brewer J, Perry M, Zhang X, Hyde DR, Godwin AR. Inhibition of zebrafish fin regeneration using in vivo electroporation of morpholinos against fgfr1 and msxb. Dev Dyn. 2006 Feb;235(2):336-46..

Interplay between the tumor suppressor p53 and TGFbeta signaling shapes embryonic body axes in Xenopus

Authors:
Takebayashi-Suzuki K, Funami J, Tokumori D, Saito A, Watabe T, Miyazono K, Kanda A, Suzuki A
Citation:
Development. 2003 Sep 1;130(17):3929-3939
Epub:
Not Epub
Abstract:
The transcription factor p53 has been shown to mediate cellular responses to diverse stresses such as DNA damage. However, the...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Takebayashi-Suzuki K, Funami J, Tokumori D, Saito A, Watabe T, Miyazono K, Kanda A, Suzuki A. Interplay between the tumor suppressor p53 and TGFbeta signaling shapes embryonic body axes in Xenopus. Development. 2003 Sep 1;130(17):3929-3939.

Islet1 selectively promotes peripheral axon outgrowth in Rohon-Beard primary sensory neurons

Authors:
Tanaka H, Nojima Y, Shoji W, Sato M, Nakayama R, Ohshima T, Okamoto H
Citation:
Dev Dyn. 2010 Nov 24. [Epub ahead of print]
Epub:
Not Epub
Abstract:
We isolated a novel zebrafish mutant, lullaby (llb), and showed that the llb locus encodes the zebrafish orthologue of isl1....
Organism or Cell Type:
zebrafish
Citation Extract:
Tanaka H, Nojima Y, Shoji W, Sato M, Nakayama R, Ohshima T, Okamoto H. Islet1 selectively promotes peripheral axon outgrowth in Rohon-Beard primary sensory neurons. Dev Dyn. 2010 Nov 24. [Epub ahead of print].

Isoform switching of Cdc6 contributes to developmental cell cycle remodeling

Authors:
Tikhmyanova N, Coleman TR
Citation:
Dev Biol. 2003 Aug 15;260(2):362-75
Epub:
Not Epub
Abstract:
Xenopus laevis early development is characterized by rapid and synchronous cleavage cycles, which consist of alternating S and...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Tikhmyanova N, Coleman TR. Isoform switching of Cdc6 contributes to developmental cell cycle remodeling. Dev Biol. 2003 Aug 15;260(2):362-75.

Kermit, a frizzled interacting protein, regulates frizzled 3 signaling in neural crest development

Authors:
Tan C, Deardorff MA, Saint-Jeannet JP, Yang J, Arzoumanian A, Klein PS
Citation:
Development. 2001 Oct 1;128(19):3665-3674.
Epub:
Not Epub
Abstract:
Wnts are a family of secreted glycoproteins that are important for multiple steps in early development. Accumulating evidence...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Tan C, Deardorff MA, Saint-Jeannet JP, Yang J, Arzoumanian A, Klein PS. Kermit, a frizzled interacting protein, regulates frizzled 3 signaling in neural crest development. Development. 2001 Oct 1;128(19):3665-3674..

Knockdown of TGFBI/BIGH3 Corneal Dystrophy-Linked Gene Leads to Developmental Impairment in Zebrafish

Authors:
Tasinato A, Belet D, Munier FL, Neuhauss S and Schorderet DF
Citation:
Invest. Ophthalmol. Vis. Sci., May 2005; 46: 4934
Epub:
Not Epub
Abstract:
Purpose: Over 25 specific mutations in the Transforming Growth Factor beta-induced gene (TGFBI, BIGH3) are so far known to be...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tasinato A, Belet D, Munier FL, Neuhauss S and Schorderet DF. Knockdown of TGFBI/BIGH3 Corneal Dystrophy-Linked Gene Leads to Developmental Impairment in Zebrafish. Invest. Ophthalmol. Vis. Sci., May 2005; 46: 4934.

Knockdown of zebrafish Lgi1a results in abnormal development, brain defects and a seizure-like behavioral phenotype

Authors:
Teng Y, Xie X, Walker S, Rempala G, Kozlowski DJ, Mumm JS, Cowell JK
Citation:
Hum Mol Genet. 2010 Sep 6. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Epilepsy is a common disorder, typified by recurrent seizures with underlying neurological disorders or disease. Approximately...
Organism or Cell Type:
zebrafish
Citation Extract:
Teng Y, Xie X, Walker S, Rempala G, Kozlowski DJ, Mumm JS, Cowell JK. Knockdown of zebrafish Lgi1a results in abnormal development, brain defects and a seizure-like behavioral phenotype. Hum Mol Genet. 2010 Sep 6. [Epub ahead of print].

Lack of de novo phosphatidylinositol synthesis leads to endoplasmic reticulum stress and hepatic steatosis in cdipt-deficient zebrafish

Authors:
Thakur PC, Stuckenholz C, Rivera MR, Davison JM, Yao JK, Amsterdam A, Sadler KC, Bahary N
Citation:
Hepatology. 2011 Aug;54(2):452-62. doi: 10.1002/hep.24349. Epub 2011 May 2
Epub:
Not Epub
Abstract:
Hepatic steatosis is the initial stage of nonalcoholic fatty liver disease (NAFLD) and may predispose to more severe hepatic...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Thakur PC, Stuckenholz C, Rivera MR, Davison JM, Yao JK, Amsterdam A, Sadler KC, Bahary N. Lack of de novo phosphatidylinositol synthesis leads to endoplasmic reticulum stress and hepatic steatosis in cdipt-deficient zebrafish. Hepatology. 2011 Aug;54(2):452-62. doi: 10.1002/hep.24349. Epub 2011 May 2.

Lethal giant larvae 2 regulates development of the ciliated organ Kupffer’s vesicle

Authors:
Tay HG, Schulze SK, Compagnon J, Foley FC, Heisenberg C-P, Yost HJ, Abdelilah-Seyfried S, Amack JD
Citation:
Development. 2013;140:1550-1559. doi:10.1242/dev.087130
Epub:
Not Epub
Abstract:
Motile cilia perform crucial functions during embryonic development and throughout adult life. Development of organs containing...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tay HG, Schulze SK, Compagnon J, Foley FC, Heisenberg C-P, Yost HJ, Abdelilah-Seyfried S, Amack JD. Lethal giant larvae 2 regulates development of the ciliated organ Kupffer’s vesicle. Development. 2013;140:1550-1559. doi:10.1242/dev.087130 .

Loss of CHSY1, a Secreted FRINGE Enzyme, Causes Syndromic Brachydactyly in Humans via Increased NOTCH Signaling

Authors:
Tian J, Ling L, Shboul M, Lee H, O'Connor B, Merriman B, Nelson SF, Cool S, Ababneh OH, Al-Hadidy A, Masri A, Hamamy H, Reversade B
Citation:
Am J Hum Genet. 2010 Dec 1. [Epub ahead of print]
Epub:
Not Epub
Abstract:
We delineated a syndromic recessive preaxial brachydactyly with partial duplication of proximal phalanges to 16.8 Mb over 4...
Organism or Cell Type:
zebrafish
Citation Extract:
Tian J, Ling L, Shboul M, Lee H, O'Connor B, Merriman B, Nelson SF, Cool S, Ababneh OH, Al-Hadidy A, Masri A, Hamamy H, Reversade B. Loss of CHSY1, a Secreted FRINGE Enzyme, Causes Syndromic Brachydactyly in Humans via Increased NOTCH Signaling. Am J Hum Genet. 2010 Dec 1. [Epub ahead of print].

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